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    Authors: Emde A. M., Pradeep C., Ferraro D. A., Ben Chetrit C. N., Sela M., Ribba B., Kam Z. & Yarden Y. (2011), Oncogene. 30, 14, p. 1631-1642
  • p53 coordinates cranial neural crest cell growth and epithelial-mesenchymal transition/delamination processes

    Authors: Rinon A., Molchadsky A., Nathan E., Yovel G., Rotter V., Sarig R. & Tzahor E. (2011), Development. 138, 9, p. 1827-1838
  • Simultaneous Inhibition of Estrogen Receptor and the HER2 Pathway in Breast Cancer: Effects of HER2 Abundance

    Authors: Emde A., Mahlknecht G., Maslak K., Ribba B., Sela M., Possinger K. & Yarden Y. (2011), Translational Oncology. 4, 5, p. 293-300
  • Mutant p53 Gain-of-Function in Cancer

    Authors: Oren M. & Rotter V. (2010), Cold Spring Harbor perspectives in biology. 2, 2
  • The ribosome as drug target: lessons from 3D structures

    Authors: Zaytzev-Bashan A., Zimmerman E., Belousoff M., Rozenberg H., Davidovich C., Wekselman I., Shapira T., Krupkin M. & Yonath A. (2010), Bulletin of the Israel Chemical Society. 25, p. 10-18
  • p53 is balancing development, differentiation and de-differentiation to assure cancer prevention

    Authors: Molchadsky A., Rivlin N., Brosh R., Rotter V. & Sarig R. (2010), Carcinogenesis. 31, 9, p. 1501-1508
  • Substrate Competitive GSK-3 Inhibitors - strategy and Implications

    Authors: Eldar-Finkelman H., Licht-Murava A., Pietrokovski S. & Eisenstein M. (2010),
  • Self-targeting by CRISPR: gene regulation or autoimmunity?

    Authors: Stern A., Keren L., Wurtzel O., Amitai G. & Sorek R. (2010), Trends in Genetics. 26, 8, p. 335-340
  • Modulation of the Vitamin D3 Response by Cancer-Associated Mutant p53

    Authors: Stambolsky P., Tabach Y., Fontemaggi G., Weisz L., Maor-Aloni R., Sigfried Z., Shiff I., Kogan I., Shay M., Kalo E., Blandino G., Simon I., Oren M. & Rotter V. (2010), Cancer Cell. 17, 3, p. 273-285
  • Steps in reductive activation of the disulfide-generating enzyme Ero1p

    Authors: Heldman N., Vonshak O., Sevier C. S., Vitu E., Mehlman T. & Fass D. (2010), Protein Science. 19, 10, p. 1863-1876
  • Tailored cancer immunotherapy using combinations of chemotherapy and a mixture of antibodies against EGF-receptor ligands

  • The Rebirth of a Phoenix: Ovarian Cancers Are Addicted to ErbB-3

    Authors: Mills G. B. & Yarden Y. (2010), Cancer Cell. 17, 3, p. 217-218
  • Cytokine-receptor interactions as drug targets

    Authors: Schreiber G. & Walter M. R. (2010), Current Opinion in Chemical Biology. 14, 4, p. 511-519
  • Polar Bears, Antibiotics, and the Evolving Ribosome (Nobel Lecture)

  • Prokaryotic transcriptomics: a new view on regulation, physiology and pathogenicity

    Authors: Sorek R. & Cossart P. (2010), Nature Reviews Genetics. 11, 1, p. 9-16
  • A Novel Translocation Breakpoint within the BPTF Gene Is Associated with a Pre-Malignant Phenotype

    Authors: Buganim Y., Goldstein I., Lipson D., Milyavsky M., Polak-Charcon S., Mardoukh C., Solomon H., Kalo E., Madar S., Brosh R., Perelman M., Navon R., Goldfinger N., Barshack I., Yakhini Z. & Rotter V. (2010), PLoS One. 5, 3, e9657
  • Repression of transposable-elements - a microRNA anti-cancer defense mechanism?

    Authors: Shalgi R., Pilpel Y. & Oren M. (2010), Trends in Genetics. 26, 6, p. 253-259
  • Direct Visualization of Protease Action on Collagen Triple Helical Structure

    Authors: Rosenblum G., Van den Steen d. S. P. E., Cohen S., Bitler A., Brand D. D., Opdenakker G. & Sagi I. (2010), PLoS One. 5, 6, e11043
  • Glatiramer acetate reduces Th-17 inflammation and induces regulatory T-cells in the CNS of mice with relapsing-remitting or chronic EAE

    Authors: Aharoni R., Eilam R., Stock A., Vainshtein A., Shezen E., Gal H., Friedman N. & Arnon R. (2010), Journal of Neuroimmunology. 225, 2-Jan, p. 100-111
  • Structural and functional bases for allosteric control of MMP activities: Can it pave the path for selective inhibition?

    Authors: Sela-Passwell N., Rosenblum G., Shoham T. & Sagi I. (2010), Biochimica Et Biophysica Acta-Molecular Cell Research. 1803, 1, p. 29-38
  • The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics

    Authors: Auerbach T., Mermershtain I., Davidovich C., Bashan A., Belousoff M., Wekselman I., Zimmerman E., Xiong L., Klepacki D., Arakawa K., Kinashi H., Mankin A. S. & Yonath A. (2010), Proceedings of the National Academy of Sciences of the United States of America. 107, 5, p. 1983-1988
  • Oncogenic mutant forms of EGFR: Lessons in signal transduction and targets for cancer therapy

    Authors: Pines G., Koestler W. J. & Yarden Y. (2010), FEBS Letters. 584, 12, p. 2699-2706
  • Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling

    Authors: Spangler J. B., Neil J. R., Abramovitch S., Yarden Y., White F. M., Lauffenburger D. A. & Wittrup K. D. (2010), Proceedings of the National Academy of Sciences of the United States of America. 107, 30, p. 13252-13257
  • p53 Regulates the Ras Circuit to Inhibit the Expression of a Cancer-Related Gene Signature by Various Molecular Pathways

    Authors: Buganim Y., Solomon H., Rais Y., Kistner D., Nachmany I., Brait M., Madar S., Goldstein I., Kalo E., Adam N., Gordin M., Rivlin N., Kogan I., Brosh R., Sefadia-Elad G., Goldfinger N., Sidransky D., Kloog Y. & Rotter V. (2010), Cancer Research. 70, 6, p. 2274-2284
  • A Small Molecule Inhibitor of Endoplasmic Reticulum Oxidation 1 (ERO1) with Selectively Reversible Thiol Reactivity

    Authors: Blais J. D., Chin K., Zito E., Zhang Y., Heldman N., Harding H. P., Fass D., Thorpe C. & Ron D. (2010), Journal of Biological Chemistry. 285, 27, p. 20993-21003
  • Ancient machinery embedded in the contemporary ribosome

    Authors: Belousoff M. J., Davidovich C., Zimmerman E., Caspi Y., Wekselman I., Rozenszajn L., Shapira T., Sade-Falk O., Taha L., Bashan A., Weiss M. S. & Yonath A. (2010), Biochemical Society Transactions. 38, p. 422-427
  • Mutation Detection with Next-Generation Resequencing through a Mediator Genome

    Authors: Wurtzel O., Dori-Bachash M., Pietrokovski S., Jurkevitch E. & Sorek R. (2010), PLoS One. 5, 12, e15628
  • TAF4b and Jun/Activating Protein-1 Collaborate to Regulate the Expression of Integrin alpha 6 and Cancer Cell Migration Properties

    Authors: Kalogeropoulou M., Voulgari A., Kostourou V., Sandaltzopoulos R., Dikstein R., Davidson I., Tora L. & Pintzas A. (2010), Molecular Cancer Research. 8, 4, p. 554-568
  • The HER2 and EGFR alliance in cancer: defects in system control

    Authors: Yarden Y. (2010), Ejc Supplements. 8, 5, p. 2-3
  • p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation

    Authors: Scherz-Shouval R., Weidberg H., Gonen C., Wilder S., Elazar Z. & Oren M. (2010), Proceedings of the National Academy of Sciences of the United States of America. 107, 43, p. 18511-18516
  • An Orange Ripening Mutant Links Plastid NAD(P)H Dehydrogenase Complex Activity to Central and Specialized Metabolism during Tomato Fruit Maturation

    Authors: Nashilevitz S., Melamed-Bessudo C., Izkovich Y., Rogachev I., Osorio S., Itkin M., Adato A., Pankratov I., Hirschberg J., Fernie A. R., Wolf S., Usadel B., Levy A., Rumeau D. & Aharoni A. (2010), Plant Cell. 22, 6, p. 1977-1997
  • Interference with the p53 family network contributes to the gain of oncogenic function of mutant p53 in hepatocellular carcinoma

    Authors: Schilling T., Kairat A., Melino G., Krammer P. H., Stremmel W., Oren M. & Mueller M. (2010), Biochemical and Biophysical Research Communications. 394, 3, p. 817-823
  • Reduced interferon receptor levels resulting from either knockdown or prolonged Type I interferon treatment promote a shift in cellular responsiveness

    Authors: Harari D., Levin D., Abramovich R. & Schreiber G. (2010),
  • Involvement of stromal p53 in tumor-stroma interactions

    Authors: Bar J., Moskovits N. & Oren M. (2010), SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. 21, 1, p. 47-54
  • Roles for Growth Factors in Cancer Progression

    Authors: Witsch E., Sela M. & Yarden Y. (2010), Physiology. 25, 2, p. 85-101
  • Hunting for Alternative Disulfide Bond Formation Pathways: Endoplasmic Reticulum Janitor Turns Professor and Teaches a Lesson

    Authors: Fass D. (2010), Molecular Cell. 40, 5, p. 685-686
  • QSOX contains a pseudo-dimer of functional and degenerate sulfhydryl oxidase domains

    Authors: Alon A., Heckler E. J., Thorpe C. & Fass D. (2010), FEBS Letters. 584, 8, p. 1521-1525
  • Cytosolic Disulfide Bond Formation in Cells Infected with Large Nucleocytoplasmic DNA Viruses

    Authors: Hakim M. & Fass D. (2010), Antioxidants & Redox Signaling. 13, 8, p. 1261-1271
  • Splicing of the Mycobacteriophage Bethlehem DnaB Intein IDENTIFICATION OF A NEW MECHANISTIC CLASS OF INTEINS THAT CONTAIN AN OBLIGATE BLOCK F NUCLEOPHILE

    Authors: Tori K., Dassa B., Johnson M. A., Southworth M. W., Brace L. E., Ishino Y., Pietrokovski S. & Perler F. B. (2010), Journal of Biological Chemistry. 285, 4, p. 2515-2526
  • The E2 Ubiquitin-conjugating Enzymes Direct Polyubiquitination to Preferred Lysines

    Authors: David Y., Ziv T., Admon A. & Navon A. (2010), Journal of Biological Chemistry. 285, 12, p. 8595-8604
  • Transcriptional control of the proliferation cluster by the tumor suppressor p53

    Authors: Brosh R. & Rotter V. (2010), Molecular BioSystems. 6, 1, p. 17-29
  • p53-dependent transcriptional regulation of EDA2R and its involvement in chemotherapy-induced hair loss

    Authors: Brosh R., Sarig R., Bar Natan N. E., Molchadsky A., Madar S., Bornstein C., Buganim Y., Shapira T., Goldfinger N., Paus R. & Rotter V. (2010), FEBS Letters. 584, 11, p. 2473-2477
  • The Intrinsic Protein Flexibility of Endogenous Protease Inhibitor TIMP-1 Controls Its Binding Interface and Affects Its Function

    Authors: Grossman M., Tworowski D., Dym O., Lee M., Levy Y., Murphy G. & Sagi I. (2010), Biochemistry. 49, 29, p. 6184-6192
  • The Biological Framework: Translational Research from Bench to Clinic

    Authors: Yarden Y. (2010), Oncologist. 15, p. 1-7
  • A single-base resolution map of an archaeal transcriptome

    Authors: Wurtzel O., Sapra R., Chen F., Zhu Y., Simmons B. A. & Sorek R. (2010), Genome Research. 20, 1, p. 133-141
  • A comparison of the binding of Interferon alpha subtypes to isolated IFNAR1 and IFNAR2 with activity in antiviral and antiproliferative assays

    Authors: Lavoie T. B., Abramovich R., Cabatu S. C., DiGioia G., Moolchan K., Pestka S. & Schreiber G. (2010),