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  • The Effect of Zinc on Amyloid beta-protein Assembly and Toxicity: a Mechanistic Investigation

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  • Increasing the potency and breadth of an HIV antibody by using structure-based rational design

    Authors: Diskin R., Scheid J. F., Marcovecchio P. M., West A. P., Klein F., Gao H., Gnanapragasam P. N., Abadir A., Seaman M. S., Nussenzweig M. C. & Bjorkman P. J. (2011), Science. 334, 6060, p. 1289-1293
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  • New opportunities in drug design of metalloproteinase inhibitors: combination between structure-function experimental approaches and systems biology

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  • Probing conformational variations at the ATPase site of the RNA helicase DbpA by high-field electron-nuclear double resonance spectroscopy

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  • Peptides and Polypeptides as Immunomodulators and Their Consequential Therapeutic Effect in Multiple Sclerosis and Other Autoimmune Diseases

    Authors: Arnon R., Sela M. & Aharoni R. (2011), Peptide Drug Discovery and Development. p. 313-335
  • Computational design of proteins targeting the conserved stem region of influenza hemagglutinin

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  • Metabolic engineering of the plant primary-secondary metabolism interface

    Authors: Aharoni A. & Galili G. (2011), Current Opinion in Biotechnology. 22, 2, p. 239-244
  • Two Phases of Mitogenic Signaling Unveil Roles for p53 and EGR1 in Elimination of Inconsistent Growth Signals

    Authors: Zwang Y., Sas-Chen A., Drier Y., Shay T., Avraham R., Lauriola M., Shema E., Lidor Nili N. E., Jacob-Hirsch J., Amariglio N., Lu Y., Mills G. B., Rechavi G., Oren M., Domany E. & Yarden Y. (2011), Molecular Cell. 42, 4, p. 524-535
  • Distinct molecular regulation of glycogen synthase kinase-3α isozyme controlled by its N-terminal region functional role in CALCIUM/CALPAIN signaling

    Authors: Azoulay-Alfaguter I., Yaffe Y., Licht-Murava A., Urbanska M., Jaworsk J., Pietrokovski S., Hirschberg K. & Eldar-Finkelman H. (2011), Journal of Biological Chemistry. 286, 15, p. 13470-13480
  • Selective loss of glycogen synthase kinase-3α in birds reveals distinct roles for GSK-3 isozymes in tau phosphorylation

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    Authors: Ben-Zeev B., Aharoni R., Nissenkorn A. & Arnon R. (2011), Medical Hypotheses. 76, 2, p. 190-193
  • Anchoring of bacterial effectors to host membranes through host-mediated lipidation by prenylation: a common paradigm

    Authors: Al-Quadan T., Price C. T., London N., Schueler-Furman O. & AbuKwaik Y. (2011), Trends in microbiology (Regular ed.). 19, 12, p. 573-579
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  • Amplification of the 20q chromosomal arm occurs early in tumorigenic transformation and may initiate cancer

    Authors: Tabach Y., Kogan-Sakin I., Buganim Y., Solomon H., Goldfinger N., Hovland R., Ke X., Oyan A. M., Kalland K., Rotter V. & Domany E. (2011), PLoS ONE. 6, 1, e14632
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  • Structural linkage between ligand discrimination and receptor activation by Type i interferons

    Authors: Thomas C., Moraga I., Levin D., Krutzik P. O., Podoplelova Y., Trejo A., Lee C., Yarden G., Vleck S. E., Glenn J. S., Nolan G. P., Piehler J., Schreiber G. & Garcia K. C. (2011), Cell. 146, 4, p. 621-632
  • Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

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  • Combining epitope-distinct antibodies to HER2: Cooperative inhibitory effects on invasive growth

    Authors: Emde A. M., Pradeep C., Ferraro D. A., Ben Chetrit C. N., Sela M., Ribba B., Kam Z. & Yarden Y. (2011), Oncogene. 30, 14, p. 1631-1642
  • P53 coordinates cranial neural crest cell growth and epithelial-mesenchymal transition/delamination processes

    Authors: Rinon A., Molchadsky A., Nathan E., Yovel G., Rotter V., Sarig R. & Tzahor E. (2011), Development. 138, 9, p. 1827-1838
  • Ribosomes: Ribozymes that survived evolution pressures but is paralyzed by tiny antibiotics

  • Generation and characterization of peptide mimotopes specific for anti erbb-2 monoclonal antibodies

    Authors: Witsch E. J., Mahlknecht G., Wakim J., Sertchook R., Bublil E., Yarden Y. & Sela M. (2011), International Immunology. 23, 6, p. 391-403
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    Authors: Emde A., Mahlknecht G., Maslak K., Ribba B., Sela M., Possinger K. & Yarden Y. (2011), Translational Oncology. 4, 5, p. 293-300
  • Mutant p53 gain-of-function in cancer.

  • The ribosome as drug target: lessons from 3D structures

    Authors: Zaytzev-Bashan A., Zimmerman E., Belousoff M., Rozenberg H., Davidovich C., Wekselman I., Shapira T., Krupkin M. & Yonath A. (2010), Bulletin of the Israel Chemical Society. 25, p. 10-18
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    Authors: Diskin R., Marcovecchio P. M. & Bjorkman P. J. (2010), Nature Structural & Molecular Biology. 17, 5, p. 608-613
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  • Substrate Competitive GSK-3 Inhibitors {single bond} strategy and Implications

    Authors: Eldar-Finkelman H., Licht-Murava A., Pietrokovski S. & Eisenstein M. (2010), Biochimica Et Biophysica Acta-Proteins And Proteomics. 1804, 3, p. 598-603
  • Erratum: Modulation of the Vitamin D3 Response by Cancer-Associated Mutant p53 (DOI:10.1016/j.ccr.2009.11.025)

    Authors: Stambolsky P., Tabach Y., Fontemaggi G., Weisz L., Maor-Aloni R., Siegfried Z., Shiff I., Kogan I., Shay M., Kalo E., Blandino G., Simon I., Oren M. & Rotter V. (2010),
  • Self-targeting by CRISPR: Gene regulation or autoimmunity?

    Authors: Stern A., Keren L., Wurtzel O., Amitai G. & Sorek R. (2010),
  • Modulation of the Vitamin D3 Response by Cancer-Associated Mutant p53

    Authors: Stambolsky P., Tabach Y., Fontemaggi G., Weisz L., Maor-Aloni R., Sigfried Z., Shiff I., Kogan I., Shay M., Kalo E., Blandino G., Simon I., Oren M. & Rotter V. (2010), Cancer Cell. 17, 3, p. 273-285
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    Authors: Heldman N., Vonshak O., Sevier C. S., Vitu E., Mehlman T. & Fass D. (2010), Protein Science. 19, 10, p. 1863-1876
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    Authors: Christoffersen N. R., Shalgi R., Frankel L. B., Leucci E., Lees M., Klausen M., Pilpel Y., Nielsen F. C., Oren M. & Lund A. H. (2010), Cell Death and Differentiation. 17, 2, p. 236-245
  • Tailored cancer immunotherapy using combinations of chemotherapy and a mixture of antibodies against EGF-receptor ligands

  • The Rebirth of a Phoenix: Ovarian Cancers Are Addicted to ErbB-3

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    Authors: Peleg Z., Saranga Y., Fahima T., Aharoni A. & Elbaum R. (2010), Physiologia Plantarum. 140, 1, p. 10-20
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    Authors: Solomon H., Brosh R., Buganim Y. & Rotter V. (2010), Discovery medicine. 48, p. 448-454
  • The EGFR/ErbB family in Breast cancer: From signalling to therapy

  • The proto-ribosome: An ancient nano-machine for peptide bond formation

    Authors: Davidovich C., Belousoff M., Wekselman I., Shapira T., Krupkin M., Zimmerman E., Bashan A. & Yonath A. (2010), Israel Journal of Chemistry. 50, 1, p. 29-35
  • Cytokine-receptor interactions as drug targets

    Authors: Schreiber G. & Walter M. R. (2010), Current Opinion in Chemical Biology. 14, 4, p. 511-519
  • Polar bears, antibiotics, and the evolving ribosome (nobel lecture)

  • A novel translocation breakpoint within the BPTF gene is associated with a pre-malignant phenotype

    Authors: Buganim Y., Goldstein I., Lipson D., Milyavsky M., Polak-Charcon S., Mardoukh C., Solomon H., Kalo E., Madar S., Brosh R., Perelman M., Navon R., Goldfinger N., Barshack I., Yakhini Z. & Rotter V. (2010), PLoS ONE. 5, 3, e9657
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  • Direct visualization of protease action on collagen triple helical structure

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  • Glatiramer acetate reduces Th-17 inflammation and induces regulatory T-cells in the CNS of mice with relapsing-remitting or chronic EAE

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    Authors: Sela-Passwell N., Rosenblum G., Shoham T. & Sagi I. (2010), Biochimica et Biophysica Acta - Molecular Cell Research. 1803, 1, p. 29-38
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    Authors: Raveh B., London N. & Schueler-Furman O. (2010), Proteins, structure, function, and bioinformatics. 78, 9, p. 2029-2040
  • Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling

    Authors: Spangler J. B., Neil J. R., Abramovitch S., Yarden Y., White F. M., Lauffenburger D. A. & Wittrup K. D. (2010), Proceedings of the National Academy of Sciences of the United States of America. 107, 30, p. 13252-13257
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