Sagol Institute

2026 Awardees

Sagol Institute for Longevity Research — Submission 2026

We are delighted to share the 2026 awardees in the Sagol Institute for Longevity Research internal grants. Our warm congratulations. The proposals span aging biology; from molecular and cellular mechanisms to organ-level trajectories, biomarkers, and emerging therapeutic strategies; and in many cases seem to spark new longevity research across the Institute. We thank every group for their contributions and look forward to the discoveries ahead.

WIS Scientist(s)	Title
Zelzer Elazar	Deciphering the Cellular, Molecular, and Mechanical Mechanisms Underlying Muscle Spindle Aging
Shlush Liran	Aging-Associated Disruption of Histone Acetylation Fuels Genome Instability in Hematopoiesis
Sharon Michal	Organ-Specific Aging Trajectories and Their Rewiring in Neurodegeneration
Segal Eran	Developing Scalable and Non-Invasive Biomarkers of Aging
Schwartz Schraga	The Molecular Aging of RNA: Time-Dependent Modification Accumulation as a Hallmark of Aging RNA
Reiner Orly	BHB-Driven Epigenetic Reprogramming in Human Brain Organoids: Modulating APOE-Dependent Neurodegenerative Trajectories
Neeman Michal	Spatial mapping of regulated cell death and metabolic stress signatures across follicle activation states in the aging mouse ovary
London Nir	Covalent pharmacological activation of ATM as an anti-aging strategy
Lansky Shifra	Structural and dynamic characterization of Caveolin-1, a key component in aging
Kimchi Tali	Defying age: Modeling longevity and resistance to age-related solitude in the blind mole-rat
Hornstein Eran, Magen Iddo	RANBP17-dependent molecular aging impacts TDP-43 pathology and aggravates ALS pathology
Hanna Jacob (Yaqub)	Synthetic embryo-derived female gonads as a biomedical treatment for age-related oocyte deficiencies
Gross Atan	Targeting mitochondrial MTCH2 as a novel approach to improve age-associated metabolic disorders
Erez Ayelet	Targeting aging-driven liver metabolism to mitigate cancer and cachexia
Amit Ido	Decoding and Targeting Pathogenic Immune Circuits in Neurodegeneration with Programmable CAR-T Therapy