All years
All Publications
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Survivorship Data in Prostate Cancer: Where Are We and Where Do We Need To Be?
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Competitive fungal commensalism mitigates candidiasis pathology
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Genome-wide association studies and polygenic risk score phenome-wide association studies across complex phenotypes in the human phenotype project
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Flagellar stator genes control a trophic shift from obligate to facultative predation and biofilm formation in a bacterial predator
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Egg multivesicular bodies elicit an LC3-associated phagocytosis-like pathway to degrade paternal mitochondria after fertilization
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Expanding and Enriching the LncRNA GeneDisease Landscape Using the GeneCaRNA Database
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Loss-of-function cancer-linked mutations in the EIF4G2 non-canonical translation initiation factor
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The GARD Prebiotic Reproduction Model Described in Order and Complexity
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Endocrinology in the multi-omics era
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Identification of gut microbiome features associated with host metabolic health in a large population-based cohort
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Quantification of beta cell carrying capacity in prediabetes
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Diabetes Telemedicine Mediterranean Diet (DiaTeleMed) Study: study protocol for a fully remote randomized clinical trial evaluating personalized dietary management in individuals with type 2 diabetes
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PIONEER big data platform for prostate cancer: lessons for advancing future real-world evidence research
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Phenome-wide associations of human aging uncover sex-specific dynamics
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Continuous glucose monitoring and intrapersonal variability in fasting glucose
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Pangenomes of human gut microbiota uncover links between genetic diversity and stress response
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Sex-specific dietary habits and their association with weight change in healthy adults
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Melanoma and microbiota: Current understanding and future directions
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CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods
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Cohort profile: Study design and baseline characteristics of an observational longitudinal weight loss cohort and biorepository of patients undergoing sleeve gastrectomy in the USA
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Bacterial SNPs in the human gut microbiome associate with host BMI
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A pathogenic variant in the uncharacterized RNF212B gene results in severe aneuploidy male infertility and repeated IVF failure
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A randomized clinical trial comparing low-fat with precision nutritionbased diets for weight loss: impact on glycemic variability and HbA1c
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Structural and biochemical analysis of a novel atypically split intein reveals a conserved histidine specific to cysteine-less inteins
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Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies
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Attractor dynamics drives self-reproduction in protobiological catalytic networks
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Impact of dietary interventions on pre-diabetic oral and gut microbiome, metabolites and cytokines
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Unanswered questions in prostate cancer - findings of an international multi-stakeholder consensus by the PIONEER consortium
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Gut microbiome modulates the effects of a personalised postprandial-targeting (PPT) diet on cardiometabolic markers: a diet intervention in pre-diabetes
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Collectively autocatalytic sets
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Wearable and digital devices to monitor and treat metabolic diseases
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Phage-display immunoprecipitation sequencing of the antibody epitope repertoire in inflammatory bowel disease reveals distinct antibody signatures
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Apoptotic cell death in diseaseCurrent understanding of the NCCD 2023
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Lifes Emergence by Protocellular Mutually Catalytic Networks
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How Well do Polygenic Risk Scores Identify Men at High Risk for Prostate Cancer? Systematic Review and Meta-Analysis
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CGMap: Characterizing continuous glucose monitor data in thousands of non-diabetic individuals: Characterizing continuous glucose monitor data in thousands of non-diabetic individuals
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Head-to-head efficacy and safety of rivaroxaban, apixaban, and dabigatran in an observational nationwide targeted trial
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Phage display sequencing reveals that genetic, environmental, and intrinsic factors influence variation of human antibody epitope repertoire
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Allergenic food protein consumption is associated with systemic IgG antibody responses in non-allergic individuals
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An expanded reference map of the human gut microbiome reveals hundreds of previously unknown species
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Soluble Receptor for Advanced Glycation End Products (sRAGE) Isoforms Predict Changes in Resting Energy Expenditure in Adults with Obesity during Weight Loss
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Genome-Wide Association Analysis of Over 170,000 Individuals from the UK Biobank Identifies Seven Loci Associated with Dietary Approaches to Stop Hypertension (DASH) Diet
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Systemic antibody responses against human microbiota flagellins are overrepresented in chronic fatigue syndrome patients
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BIPSA code base for designing and coding of a Phage ImmunoPrecipitation Oligo Library
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Antibody signatures in inflammatory bowel disease: current developments and future applications
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Effects of personalized diets by prediction of glycemic responses on glycemic control and metabolic health in newly diagnosed T2DM: a randomized dietary intervention pilot trial
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Prediction of type 2 diabetes mellitus onset using logistic regression-based scorecards
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BREAst Cancer Personalised NuTrition (BREACPNT): dietary intervention in breast cancer survivors treated with endocrine therapy a protocol for a randomised clinical trial
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Prediction of Personal Glycemic Responses to Food for Individuals With Type 1 Diabetes Through Integration of Clinical and Microbial Data
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Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3UTR protect against ALS
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Phenotypic correlates of the working dog microbiome
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Recording bacterial responses to changes in the gut environment
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Effect of a Personalized Diet to Reduce Postprandial Glycemic Response vs a Low-fat Diet on Weight Loss in Adults with Abnormal Glucose Metabolism and Obesity: A Randomized Clinical Trial
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Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance
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Microbiome and metabolome features of the cardiometabolic disease spectrum
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Micellar Composition Affects Lipid Accretion Kinetics in Molecular Dynamics Simulations: Support for Lipid Network Reproduction
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The Gut Microbiome of Adults With Type 1 Diabetes and Its Association With the Host Glycemic Control
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Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease
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Research gaps and opportunities in precision nutrition: an NIH workshop report
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Estimating the effect of cesarean delivery on long-term childhood health across two countries
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DOP53 In-depth characterisation of the serum antibody epitope repertoire in Inflammatory Bowel Disease by high-throughput phage-displayed immunoprecipitation sequencing
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Nowcasting the spread of SARS-CoV-2
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An atlas of robust microbiome associations with phenotypic traits based on large-scale cohorts from two continents
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The GeneCards Suite
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Pls1 Is a Peroxisomal Matrix Protein with a Role in Regulating Lysine Biosynthesis
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Clinical efficacy of fecal microbial transplantation treatment in adults with moderate-to-severe atopic dermatitis
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New Approaches to Profile the Microbiome for Treatment of Neurodegenerative Disease
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Evidence for cutaneous dysbiosis in dystrophic epidermolysis bullosa
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SARS-CoV-2 antibody testing for estimating COVID-19 prevalence in the population
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Structured elements drive extensive circular RNA translation
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Estimating heritability of glycaemic response to metformin using nationwide electronic health records and population-sized pedigree
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Identification of bacteria-derived HLA-bound peptides in melanoma
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GeneCaRNA: A Comprehensive Gene-centric Database of Human Non-coding RNAs in the GeneCards Suite
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The gut microbiome: a key player in the complexity of amyotrophic lateral sclerosis (ALS)
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Personalized Postprandial Glucose ResponseTargeting Diet Versus Mediterranean Diet for Glycemic Control in Prediabetes
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The Key Role of Patient Involvement in the Development of Core Outcome Sets in Prostate Cancer
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Diversity and functional landscapes in the microbiota of animals in the wild
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Self-reproducing catalytic micelles as nanoscopic protocell precursors
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Potential role of indolelactate and butyrate in multiple sclerosis revealed by integrated microbiome-metabolome analysis
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Hospital load and increased COVID-19 related mortality in Israel
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Cross-reactive antibodies against human coronaviruses and the animal coronavirome suggest diagnostics for future zoonotic spillovers
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10 K: a largescale prospective longitudinal study in Israel
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COVID-19 dynamics after a national immunization program in Israel
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Population-wide diversity and stability of serum antibody epitope repertoires against human microbiota
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Anosmia, ageusia, and other COVID-19-like symptoms in association with a positive SARS-CoV-2 test, across six national digital surveillance platforms: an observational study
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New Approaches to Profile the Microbiome for Treatment of Neurodegenerative Disease
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A Prediction Model to Prioritize Individuals for a SARS-CoV-2 Test Built from National Symptom Surveys
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Stress-related emotional and behavioural impact following the first COVID-19 outbreak peak
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Dynamic lipid aptamers: non-polymeric chemical path to early life
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Prediction of Childhood Obesity from Nationwide Health Records
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The long-term genetic stability and individual specificity of the human gut microbiome
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Editor Profile: Eli Arama
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Unified platform for genetic and serological detection of COVID-19 with single-molecule technology
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Signals of hope: gauging the impact of a rapid national vaccination campaign
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Reporting guidelines for human microbiome research: the STORMS checklist
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DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells
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Large-scale association analyses identify host factors influencing human gut microbiome composition
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Challenges of conducting a remote behavioral weight loss study: Lessons learned and a practical guide
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Biochemical and Structural Characterization of an Unusual and Naturally Split Class 3 Intein
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Rationale and design of a randomised controlled trial testing the effect of personalised diet in individuals with pre-diabetes or type 2 diabetes mellitus treated with metformin
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Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth
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A reference map of potential determinants for the human serum metabolome
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Building an international consortium for tracking coronavirus health status
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Axes of a revolution: challenges and promises of big data in healthcare
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A framework for identifying regional outbreak and spread of COVID-19 from one-minute population-wide surveys
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The human tumor microbiome is composed of tumor type-specific intracellular bacteria
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Rare Variant Burden Analysis within Enhancers Identifies CAV1 as an ALS Risk Gene
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The gut microbiome and individual-specific responses to diet
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High-throughput interrogation of programmed ribosomal frameshifting in human cells
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Visualizing the structure and motion of the long noncoding RNA HOTAIR
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Introducing PIONEER: a project to harness big data in prostate cancer research
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The road ahead in genetics and genomics
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A unified nomenclature for vertebrate olfactory receptors
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Gene Architecture and Sequence Composition Underpin Selective Dependency of Nuclear Export of Long RNAs on NXF1 and the TREX Complex
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Non-lethal message from the Holy Land: The first international conference on nonapoptotic roles of apoptotic proteins
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Identifying gut microbes that affect human health
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Clinically Accurate Prediction of Glucose Levels in Patients with Type 1 Diabetes
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Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome
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Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome (vol 182, pg 1460, 2020): Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome (Cell (2020) 182(6) (14601473.e17), (S0092867420309983), (10.1016/j.cell.2020.08.007))
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Prediction of gestational diabetes based on nationwide electronic health records
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Rich data sets could end costly drug discovery
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Longitudinal symptom dynamics of COVID-19 infection
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A new MEIOB mutation is a recurrent cause for azoospermia and testicular meiotic arrest
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Noncoding deletions reveal a gene that is critical for intestinal function
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Potential roles of gut microbiome and metabolites in modulating ALS in mice
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Genome analysis and knowledge-driven variant interpretation with TGex
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Systematic interrogation of human promoters
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The rationale and design of the personal diet study, a randomized clinical trial evaluating a personalized approach to weight loss in individuals with pre-diabetes and early-stage type 2 diabetes
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Protobiotic Systems Chemistry Analyzed by Molecular Dynamics
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Enceladus: First Observed Primordial Soup Could Arbitrate Origin-of-Life Debate
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Dissecting splicing decisions and cell-to-cell variability with designed sequence libraries
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A cancer associated somatic mutation in LC3B attenuates its binding to E1-like ATG7 protein and subsequent lipidation
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The pros, cons, and many unknowns of probiotics
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Erratum: Deciphering the rules by which 5-UTR sequences affect protein expression in yeast (Proceedings of the National Academy of Sciences of the United States of America (2013) 110 (E2792E2801) DOI: 10.1073/pnas.1222534110)
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Sequence determinants of polyadenylation-mediated regulation
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A mesophilic cysteine-less split intein for protein trans-splicing applications under oxidizing conditions
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Environment dominates over host genetics in shaping human gut microbiota
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What Can Immunologists Learn from Systems Approaches?
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International conference on Cell Death in Cancer and Toxicology 2018 (CDCT-2018)
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Role of the gut microbiota in nutrition and health
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The Helix Twist: Damage and Repair Follows the DNA Minor Groove
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Probiotics administration following sleeve gastrectomy surgery: a randomized double-blind trial
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Prediction of acute myeloid leukaemia risk in healthy individuals
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Mutations in AIFM1 cause an X-linked childhood cerebellar ataxia partially responsive to riboflavin
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Replication of Simulated Prebiotic Amphiphilic Vesicles in a Finite Environment Exhibits Complex Behavior That Includes High Progeny Variability and Competition
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A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation
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Functional characterization of the p53 "mutome"
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Caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion
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Meta-analysis of human genome-microbiome association studies: The MiBioGen consortium initiative
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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
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Systems protobiology: origin of life in lipid catalytic networks
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Unraveling the determinants of microRNA mediated regulation using a massively parallel reporter assay
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GeneHancer: Genome-wide integration of enhancers and target genes in GeneCards
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CDPs: caspase-dependent non-lethal cellular processes
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Controlling caspase activity in life and death
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Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators
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MalaCards: an amalgamated human disease compendium with diverse clinical and genetic annotation and structured search
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The landscape of sex-differential transcriptome and its consequent selection in human adults
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p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis
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Identification and Characterization of Differentially-Regulated Type IVb Pilin Genes Necessary for Predation in Obligate Bacterial Predators /631/326/1320 /631/326/325 /38 article
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Sequence features of viral and human Internal Ribosome Entry Sites predictive of their activity
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Involvement of a gut-retina axis in protection against dietary glycemia-induced age-related macular degeneration
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Development of a screening system for inteins active in protein splicing based on intein insertion into the LacZ alpha-peptide
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A familial study of azoospermic men identifies three novel causative mutations in three new human azoospermia genes
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Systematic Investigation of Transcription Factor Activity in the Context of Chromatin Using Massively Parallel Binding and Expression Assays
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Rational confederation of genes and diseases: NGS interpretation via GeneCards, MalaCards and VarElect
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Next-generation sequencing of patients with congenital anosmia
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TECPR2 mutations cause a new subtype of familial dysautonomia like hereditary sensory autonomic neuropathy with intellectual disability
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A role for TENM1 mutations in congenital general anosmia
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GeneAnalytics: An Integrative Gene Set Analysis Tool for Next Generation Sequencing, RNAseq and Microarray Data
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The GeneCards suite: From gene data mining to disease genome sequence analyses
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A Krebs Cycle Component Limits Caspase Activation Rate through Mitochondrial Surface Restriction of CRL Activation
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
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Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations
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The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles
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Identification of a Functional Risk Variant for Pemphigus Vulgaris in the ST18 Gene
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The de-ubiquitylating enzyme DUBA is essential for spermatogenesis in Drosophila
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VarElect: The phenotype-based variation prioritizer of the GeneCards Suite
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Genic insights from integrated human proteomics in GeneCards.
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An extended cyclic di-GMP network in the predatory bacterium Bdellovibrio bacteriovorus
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Integrated identification of disease-gene links and their utility in next-generation sequencing interpretation
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The human olfactory transcriptome
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ORDB, HORDE, ODORactor and other on-line knowledge resources of olfactory receptor-odorant interactions
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Cancer therapeutic approach based on conformational stabilization of mutant p53 protein by small peptides
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A minimalistic resource allocation model to explain ubiquitous increase in protein expression with growth rate
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Massively Parallel Interrogation of the Effects of Gene Expression Levels on Fitness
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Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace
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Comparative genetics: Systematic discovery of cap-independent translation sequences in human and viral genomes
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Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples
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Whole-exome sequencing in undiagnosed genetic diseases: Interpreting 119 trios
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Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling
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Exome sequencing as a differential diagnosis tool: Resolving mild trichohepatoenteric syndrome
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Noise in gene expression is coupled to growth rate
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A day in the life of the meta-organism: Diurnal rhythms of the intestinal microbiome and its host
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PathCards: Multi-source consolidation of human biological pathways
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Cell-cycle progress in obligate predatory bacteria is dependent upon sequential sensing of prey recognition and prey quality cues
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Personalized Nutrition by Prediction of Glycemic Responses
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Non-caloric artificial sweeteners and the microbiome: Findings and challenges
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Systematic Dissection of the Sequence Determinants of Gene 3 End Mediated Expression Control
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Core promoter sequence in yeast is a major determinant of expression level
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Absence of α-and β-dystroglycan is associated with Walker-Warburg syndrome
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GenoExp: A web tool for predicting gene expression levels from single nucleotide polymorphisms
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Editorial overview: Genome architecture and expression
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Unraveling determinants of transcription factor binding outside the core binding site
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Artificial Sweeteners Induce Glucose Intolerance by Altering the Gut Microbiota: Editorial comment
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Artificial sweeteners induce glucose intolerance by altering the gut microbiota
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A shared architecture for promoters and enhancers
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MOPED enables discoveries through consistently processed proteomics data
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In pursuit of design principles of regulatory sequences
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Host-parasite network structure is associated with community-level immunogenetic diversity
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Paternal mitochondrial destruction after fertilization is mediated by a common endocytic and autophagic pathway in drosophila
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Probing the effect of promoters on noise in gene expression using thousands of designed sequences
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The grammar of transcriptional regulation
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Reduced selection and accumulation of deleterious mutations in genes exclusively expressed in men
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An atypical naturally split intein engineered for highly efficient protein labeling
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Transkingdom control of microbiota diurnal oscillations promotes metabolic homeostasis
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Multispecies population dynamics of prebiotic compositional assemblies
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Molecular dissection of the genetic mechanisms that underlie expression conservation in orthologous yeast ribosomal promoters
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In and out: an analysis of epibiotic vs periplasmic bacterial predators
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MalaCards: A Comprehensive automatically-mined Database of human diseases
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Landscape and variation of RNA secondary structure across the human transcriptome
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Quasispecies in population of compositional assemblies
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Alternative germ cell death pathway in drosophila involves HtrA2/Omi, lysosomes, and a caspase-9 counterpart
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Determinants of nucleosome positioning
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Non-redundant compendium of human ncRNA genes in GeneCards
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An overview of synergistic data tools for biological scrutiny
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General Olfactory Sensitivity Database (GOSdb): Candidate Genes and their Genomic Variations
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TECPR2:A new autophagy link for neurodegeneration
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Promoter Sequence Determines the Relationship between Expression Level and Noise
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Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise
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The MATCHIT automaton: Exploiting compartmentalization for the synthesis of branched polymers
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Measurements of the Impact of 3 End Sequences on Gene Expression Reveal Wide Range and Sequence Dependent Effects
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Promoters maintain their relative activity levels under different growth conditions
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Nucleosome maps of the human cytomegalovirus genome reveal a temporal switch in chromatin organization linked to a major IE protein
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MalaCards: An integrated compendium for diseases and their annotation
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Deficiency of Asparagine Synthetase Causes Congenital Microcephaly and a Progressive Form of Encephalopathy
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Robust Prediction of Expression Differences among Human Individuals Using Only Genotype Information
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Predicting Disease Risk Using Bootstrap Ranking and Classification Algorithms
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Deciphering the rules by which 5'-UTR sequences affect protein expression in yeast
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Fixated on fixation - using ChIP to interrogate the dynamics of chromatin interactions
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Oriented covalent immobilization of antibodies for measurement of intermolecular binding forces between zipper-like contact surfaces of split inteins
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HORDE: Comprehensive resource for olfactory receptor genomics
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Sequence features of yeast and human core promoters that are predictive of maximal promoter activity
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By their genes ye shall know them: Genomic signatures of predatory bacteria
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Inferring gene expression from ribosomal promoter sequences, a crowdsourcing approach
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Mutation in TECPR2 reveals a role for autophagy in hereditary spastic paraparesis
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Is There an Optimal Level of Open-Endedness in Prebiotic Evolution?
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New insights into replication origin characteristics in metazoans
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Sporoptosis: Sowing the Seeds of Nuclear Destruction
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Association of the type 2 diabetes mellitus susceptibility gene, TCF7L2, with schizophrenia in an Arab-Israeli family sample
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From catalogue to function
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Personal receptor repertoires: olfaction as a model
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Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters
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Cell lineage analysis of the mammalian female germline
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Genome-wide Measurement of RNA Folding Energies
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DOCK4 and CEACAM21 as novel schizophrenia candidate genes in the Jewish population
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Genome sequence of the pattern-forming social bacterium: Paenibacillus dendritiformis C454 Chiral Morphotype
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Caspase levels and execution efficiencies determine the apoptotic potential of the cell
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MOPED: Model Organism Protein Expression Database
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Evolutionary grass roots for odor recognition
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Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeast
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Excess Mutual Catalysis Is Required for Effective Evolvability
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The NAB-Brk signal bifurcates at JNK to independently induce apoptosis and compensatory proliferation
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There Is More to Life than Death: A Moonlighting Function of a Bcl-2 Member
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High nucleosome occupancy is encoded at X-linked gene promoters in C. elegans
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In-silico human genomics with GeneCards
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New modularity of DAP-kinases: Alternative splicing of the DRP-1 gene produces a Zipk-like isoform
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Replication of simulated prebiotic amphiphile vesicles controlled by experimental lipid physicochemical properties
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Computational Prediction of RNA Structural Motifs Involved in Post-Transcriptional Regulatory Processes
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Compensation for differences in gene copy number among yeast ribosomal proteins is encoded within their promoters
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Mapping of molecular pathways, biomarkers and drug targets for diabetic nephropathy
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Synthetic lethal hubs associated with vincristine resistant neuroblastoma
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Myosin drives autophagy in a pathway linking Atg1 to Atg9
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Understanding the transcriptome through RNA structure
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Activity, specificity and structure of I-Bth0305I: A representative of a new homing endonuclease family
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Identification of plant RAD52 homologs and characterization of the arabidopsis thaliana RAD52-like genes
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Atg8: An autophagy-related ubiquitin-like protein family
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Distinct molecular regulation of glycogen synthase kinase-3α isozyme controlled by its N-terminal region functional role in CALCIUM/CALPAIN signaling
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Selective loss of glycogen synthase kinase-3α in birds reveals distinct roles for GSK-3 isozymes in tau phosphorylation
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Omics Data Management and Annotation
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How Transcription Factors Identify Regulatory Sites in Genomic Sequence
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Identification of new schizophrenia susceptibility loci in an ethnically homogeneous, family-based, Arab-Israeli sample
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Axonal degeneration is regulated by the apoptotic machinery or a NAD +-sensitive pathway in insects and mammals
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Spontaneous chiral symmetry breaking in early molecular networks
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Long noncoding RNA as modular scaffold of histone modification complexes
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A novel F-box protein is required for caspase activation during cellular remodeling in Drosophila
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Substrate Competitive GSK-3 Inhibitors {single bond} strategy and Implications
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Gradients of a Ubiquitin E3 Ligase Inhibitor and a Caspase Inhibitor Determine Differentiation or Death in Spermatids
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Lymphoblast and brain expression of AHI1 and the novel primate-specific gene, C6orf217, in schizophrenia and bipolar disorder
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Nucleosome sequence preferences influence in vivo nucleosome organization
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Contribution of histone sequence preferences to nucleosome organization: Proposed definitions and methodology
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Meig1 deficiency causes a severe defect in mouse spermatogenesis
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Fine mapping of AHI1 as a schizophrenia susceptibility gene: From association to evolutionary evidence
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GeneCards Version 3: the human gene integrator.
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Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project
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Replication and darwinian selection define life's origin
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Systematic inference of copy-number genotypes from personal genome sequencing data reveals extensive olfactory receptor gene content diversity
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Overlapping codes within protein-coding sequences
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Genome sequence of the pattern forming Paenibacillus vortex bacterium reveals potential for thriving in complex environments
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Mutation detection with next-generation resequencing through a mediator genome
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p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy
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Genome-wide measurement of RNA secondary structure in yeast
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Widespread compensatory evolution conserves DNA-encoded nucleosome organization in yeast
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Splicing of the mycobacteriophage bethlehem DnaB intein: Identification of a new mechanistic class of inteins that contain an obligate block f nucleophile
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High nucleosome occupancy is encoded at human regulatory sequences
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The DNA-encoded nucleosome organization of a eukaryotic genome
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Proteome-wide prediction of acetylation substrates
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GeneDecks: Paralog hunting and gene-set distillation with genecards annotation
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Drosophila Past1 is involved in endocytosis and is required for germline development and survival of the adult fly
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Common peptides shed light on evolution of Olfactory Receptors
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Fractured genes: A novel genomic arrangement involving new split inteins and a new homing endonuclease family
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Poly(dA:dT) tracts: major determinants of nucleosome organization
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GIFtS: Annotation landscape analysis with GeneCards
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Human olfaction: from genomic variation to phenotypic diversity
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Mutations and lethality in simulated prebiotic networks
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Gene expression divergence in yeast is coupled to evolution of DNA-encoded nucleosome organization
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Incorporating nucleosomes into thermodynamic models of transcription regulation
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Evidence for an interaction of schizophrenia susceptibility loci on chromosome 6q23.3 and 10q24.33-q26.13 in Arab Israeli families
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Can't live without them, can live with them: Roles of caspases during vital cellular processes
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Further evidence for association of the RGS2 gene with antipsychotic-induced parkinsonism: Protective role of a functional polymorphism in the 3-untranslated region
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Modeling interactions between adjacent nucleosomes improves genome-wide predictions of nucleosome occupancy
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From DNA sequence to transcriptional behaviour: A quantitative approach
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What controls nucleosome positions?
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Bacterial intein-like domains of predatory bacteria: A new domain type characterized in Bdellovibrio bacteriovorus
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Geometric constraints on neuronal connectivity facilitate a concise synaptic adhesive code
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Genome analysis of the platypus reveals unique signatures of evolution (Nature (2008) 453, (175-183))
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High-resolution copy-number variation map reflects human olfactory receptor diversity and evolution
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Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation
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Proteome-Based Comparative Analyses of Growth Stages Reveal New Cell Cycle-Dependent Functions in the Predatory Bacterium Bdellovibrio bacteriovorus
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Reconstruction of Cell Lineage Trees in Mice
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Preferentially Quantized Linker DNA Lengths in Saccharomyces cerevisiae
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Predicting expression patterns from regulatory sequence in Drosophila segmentation
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A feature-based approach to modeling protein-DNA interactions
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Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells
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New Insights into the Autoinhibition Mechanism of Glycogen Synthase Kinase-3β
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Why do young women smoke? V. Role of direct and interactive effects of nicotinic cholinergic receptor gene variation on neurocognitive function
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Using expression profiles of Caenorhabditis elegans neurons to identify genes that mediate synaptic connectivity
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Distinct modes of regulation by chromatin encoded through nucleosome positioning signals
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Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells
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Revealing targeted therapy for human cancer by gene module maps
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Systematic functional characterization of cis-regulatory motifs in human core promoters
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Reversal of aging by NFκB blockade
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Genome-wide linkage scan, fine mapping, and haplotype analysis in a large, inbred, Arab Israeli pedigree suggest a schizophrenia susceptibility locus on chromosome 20p13
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Computational prediction of RNA structural motifs involved in posttranscriptional regulatory processes
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A multi-scaled approach to artificial life simulation with P Systems and Dissipative Particle Dynamics
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Stemness, cancer and cancer stem cells
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Estimating cell depth from somatic mutations
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Novel definition files for human GeneChips based on GeneAnnot
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Association of the dopamine receptor interacting protein gene, NEF3, with early response to antipsychotic medication
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Coevolution of compositional protocells and their environment
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A feature-based approach to modeling protein-DNA interactions
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Pharmacogenetics of glatiramer acetate therapy for multiple sclerosis reveals drug-response markers
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Haplotype structure and selection of the MDM2 oncogene in humans
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Mutations in olfactory signal transduction genes are not a major cause of human congenital general anosmia
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A module of negative feedback regulators defines growth factor signaling
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Trans protein splicing of cyanobacterial split inteins in endogenous and exogenous combinations
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A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila
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The role of site accessibility in microRNA target recognition
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Rapid assessment of correlated amino acids from pair-to-pair (P2P) substitution matrices
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The Drosophila caspases strica and dronc function redundantly in programmed cell death during oogenesis
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Search for hand osteoarthritis susceptibility locus on chromosome 6p12.3-p12.1
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Genetic elucidation of human hyperosmia to isovaleric acid
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Occurrence of protein structure elements in conserved sequence regions
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Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs
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Zinc-ion binding and cytokine activity regulation pathways predicts outcome in relapsing-remitting multiple sclerosis
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Refining intra-protein contact prediction by graph analysis
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A transcriptional program mediating entry into cellular quiescence
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A pair-to-pair amino acids substitution matrix and its applications for protein structure prediction
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InSite: A computational method for identifying protein-protein interaction binding sites on a proteome-wide scale
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Question 7: The first units of life were not simple cells
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Molecular Recognition in Biology: Models for Analysis of Protein-Ligand Interactions
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Decoding global gene expression programs in liver cancer by noninvasive imaging
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Association of the RGS2 gene with extrapyramidal symptoms induced by treatment with antipsychotic medication
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Motif module map reveals enforcement of aging by continual NF-κB activity
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ZIPK: A unique case of murine-specific divergence of a conserved vertebrate gene
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Widespread ectopic expression of olfactory receptor genes
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Detection of apoptosis by terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling and acridine orange in Drosophila embryos and adult male gonads
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Expoldb: Expression linked polymorphism database with inbuilt tools for analysis of expression and simple repeats
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The association of DNA sequence variation at the MAOA genetic locus with quantitative behavioural traits in normal males
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Variations in the human olfactory receptor pathway
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ATM haplotypes and breast cancer risk in Jewish high-risk women
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The two Drosophila cytochrome C proteins can function in both respiration and caspase activation
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Why do young women smoke? I. Direct and interactive effects of environment, psychological characteristics and nicotinic cholinergic receptor genes
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Ancient genomic architecture for mammalian olfactory receptor clusters
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Cytochrome c-d regulates developmental apoptosis in the Drosophila retina
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Genetic basis of olfactory deficits
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Nuclear import of Ho endonuclease utilizes two nuclear localization signals and four importins of the ribosomal import system
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The trace amine receptor 4 gene is not associated with schizophrenia in a sample linked to chromosome 6q23 [3]
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Hsp90 recognizes a common surface on client kinases
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AHI1, a pivotal neurodevelopmental gene, and C6orf217 are associated with susceptibility to schizophrenia
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Compositional complementarity and prebiotic ecology in the origin of life
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A genomic code for nucleosome positioning
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A probabilistic classifier for olfactory receptor pseudogenes
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LEMD3: The gene responsible for bone density disorders (osteopoikilosis)
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Assessing natural variations in gene expression in humans by comparing with monozygotic twins using microarrays
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Mitochondrial carrier homolog 2 is a target of tBID in cells signaled to die by tumor necrosis factor alpha
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Enhanced statistics for local alignment of multiple alignments improves prediction of protein function and structure
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Genotype phenotype correlations in Israeli colorectal cancer patients
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Algal viruses with distinct intraspecies host specificities include identical intein elements
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Genome-wide midrange transcription profiles reveal expression level relationships in human tissue specification
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The autophagy-associated Atg8 gene family operates both under favourable growth conditions and under starvation stresses in Arabidopsis plants
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GeneTide - Terra Incognita Discovery Endeavor: A new transcriptome focused member of the GeneCards/GeneNote suite of databases
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Modular genes with metazoan-specific domains have increased tissue specificity
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Polymer gard: Computer simulation of covalent bond formation in reproducing molecular assemblies
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Separating the contribution of translational and rotational diffusion to protein association
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Alternative splicing and gene duplication are inversely correlated evolutionary mechanisms
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Conservation anchors in the vertebrate genome
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Early systems biology and prebiotic networks
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One-Block CYRCA: An automated procedure for identifying multiple-block alignments from single block queries
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Graded artificial chemistry in restricted boundaries
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Protein splicing and auto-cleavage of bacterial intein-like domains lacking a C '-flanking nucleophilic residue
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The lipid world: From catalytic and informational headgroups to micelle replication and evolution without nucleic acids
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GeneAnnot: Comprehensive two-way linking between oligonucleotide array probesets and GeneCards genes
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Genomic profiling of interpopulation diversity guides prioritization of candidate-genes for autoimmunity
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The canine olfactory subgenome
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The olfactory receptor universe - From whole genome analysis to structure and evolution
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Prospects of a computational origin of life endeavor
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Protein Splicing of Inteins with Atypical Glutamine and Aspartate C-terminal Residues
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NIPBL gene responsible for Cornelia de Lange syndrome, a severe developmental disorder
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A new gene for the Charcot-Marie-Tooth disorder
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5-lipoxygenase activating protein (ALOX5AP): Association with cardiovascular infarction and stroke
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Prediction of the odorant binding site of olfactory receptor proteins by human-mouse comparisons
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Is the G72/G30 locus associated with schizophrenia? Single nucleotide polymorphisms, haplotypes, and gene expression analysis
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Recent innovations in the genecards suite
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Network analysis of protein structures identifies functional residues
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Loss of olfactory receptor genes coincides with the acquisition of full trichromatic vision in primates
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Probability rule for chiral recognition
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New type of polyubiquitin-like genes with intein-like autoprocessing domains
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Computer simulation of protocells
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An eNose algorithm for identifying chemicals and determining their concentration
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GeneLoc: Exon-based integration of human genome maps
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Human Olfactory Receptors
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Mesobiotic emergence: Molecular and ensemble complexity in early evolution
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A feature extraction method for chemical sensors in electronic noses
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Human specific loss of olfactory receptor genes
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GeneNote: Whole genome expression profiles in normal human tissues
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Module networks: Identifying regulatory modules and their condition-specific regulators from gene expression data
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From subgenome analysis to protein structure
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Natural selection on the olfactory receptor gene family in humans and chimpanzees
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Human gene-centric databases at the Weizmann Institute of science: GeneCards, UDB, CroW 21 and HORDE
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Distribution and function of new bacterial intein-like protein domains
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Caspase activity and a specific cytochrome c are required for sperm differentiation in Drosophila
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Towards an odor communication system
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Distribution of split DnaE inteins in cyanobacteria
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Different noses for different people
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New types of conserved sequence domains in DNA-binding regions of homing endonucleases
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A new gene causing sudden cardiac death in children from a Bedouin tribe in North Israel
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USH3A transcripts encode clarin-1, a four-transmembrane-domain protein with a possible role in sensory synapses
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GeneCards™ 2002: Towards a complete, object-oriented, human gene compendium
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Evidence for positive selection and population structure at the human MAO-A gene
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Pharmacogenetic development of personalized medicine: Multiple sclerosis treatment as a model
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Test of a statistical model for molecular recognition in biological repertoires
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Population differences in haplotype structure within a human olfactory receptor gene cluster
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DEFOG: A practical scheme for deciphering families of genes
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Computational capacity of an odorant discriminator: The linear separability of curves
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The human olfactory subgenome: from sequence to structure and evolution
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Exact Inference in Networks with Discrete Children of Continuous Parents
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Consistency analysis of similarity between multiple alignments: Prediction of protein function and fold structure from analysis of local sequence motifs
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Architecture and anatomy of the genomic locus encoding the human leukemia-associated transcription factor RUNX1/AML1
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Visualizing large-scale genomic sequences: The GESTALT workbench produces interactive genome graphs for quick and intuitive sequence interpretation
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Mouse-human orthology relationships in an olfactory receptor gene cluster
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The Lipid World
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Estimating the size of the olfactory repertoire
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A missense mutation in a highly conserved region of CASQ2 is associated with autosomal recessive catecholamine-induced polymorphic ventricular tachycardia in Bedouin families from Israel
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Initial sequencing and analysis of the human genome
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The UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase gene is mutated in recessive hereditary inclusion body myopathy
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The molecular roots of compositional inheritance
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Intein spread and extinction in evolution
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Mucolipidosis type IV: Novel MCOLN1 mutations in Jewish and Mon-Jewish patients and the frequency of the disease in the Ashkenazi Jewish population
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The RUNX3 gene - Sequence, structure and regulated expression
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The complete human olfactory subgenome
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Doublecortin mutations cluster in evolutionarily conserved functional domains
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Compositional genomes: Prebiotic information transfer in mutually catalytic noncovalent assemblies
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Identification of the gene causing mucolipidosis type IV
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Identification and characterization of coding single-nucleotide polymorphisms within a human olfactory receptor gene cluster
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Prebiotic evolution of amphiphilic assemblies far from equilibrium: From compositional information to sequence-based biopolymers
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Composing life
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The genomic structure of human olfactory receptor genes
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Harvesting the human genome: The Israeli perspective
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Increased coverage of protein families with the Blocks Database servers
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GESTALT: A workbench for automatic integration and visualization of large-scale genomic sequence analyses
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The olfactory receptor gene superfamily: Data mining, classification, and nomenclature
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Dichotomy of single-nucleotide polymorphism haplotypes in olfactory receptor genes and pseudogenes
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Sequence, structure, and evolution of a complete human olfactory receptor gene cluster
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Blocks-based methods for detecting protein homology
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Fine-tuning an engineered intein
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Blocks+: A non-redundant database of protein alignment blocks derived from multiple compilations
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kPROT: A knowledge-based scale for the propensity of residue orientation in transmembrane segments. Application to membrane protein structure prediction
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The variable and conserved interfaces of modeled olfactory receptor proteins
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Isolation and characterization of a split B-type DNA polymerase from the archaeon Methanobacterium thermoautotrophicum ΔH
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GARDobes: Primordial cell nano-precursors with organic catalysis, compositional genome and capacity to evolve
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Molecular biology of olfactory receptors
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Primate evolution of an olfactory receptor cluster: Diversification by gene conversion and recent emergence of pseudogenes
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Configuration of the catalytic GIY-YIG domain of intron endonuclease I-Tevl: Coincidence of computational and molecular findings
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Olfaction: Good reception in fruitfly antennae