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    RNA transmission between honeybees and their microbiome

    Date:
    02
    Thursday
    May
    2024
    Lecture / Seminar
    Time: 15:00-16:00
    Location: Nella and Leon Benoziyo Building for Biological Sciences
    Lecturer: Dr. Eyal Maori
    Organizer: Department of Biomolecular Sciences
    Contact: levana.ayvazo@weizmann.ac.il
    Abstract: Transmissible RNA has emerged as a means of communication between organisms, bot ... Read more Transmissible RNA has emerged as a means of communication between organisms, both within and across different kingdoms of life. Donor organisms transmit long base-paired RNA, tRNA-fragments, and other small RNAs to elicit RNAi responses in recipient individuals, affecting their gene expression and phenotypes. Honeybees offer a unique opportunity to study RNA transmission since they possess a transmissible RNA pathway through which they share RNAs between individuals and across generations via the secretion and ingestion of worker- and royal jelly. We hypothesised that members of the gut microbiome exploit the same pathway and transmit RNA to their honeybee host. We show that RNA originating from a gut-restricted bacterium, Snodgrassella alvi (S. alvi), can be detected in worker- and royal jellies. Endogenous S. alvi RNAs are present also in systemic larval tissues in the absence of bacterial genomic DNA, indicating jelly-mediated microbiome RNA uptake and systemic spread within recipient larvae. Characterisation of transmissible S. alvi RNA reveals enrichment of specific rRNA and tRNA fragments in systemic larval tissues. The transmitted RNA fragments could potentially be involved in RNAi and have the capacity to target honeybee pathogens, such as Nosema and viruses. An expanded transmissible RNA pathway and its potential cooperative roles in honeybee- microbiome interactions will be discussed.
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    The Language of Bacterial Pathogens, Commensals, and Biomedical Potentials

    Date:
    08
    Thursday
    February
    2024
    Lecture / Seminar
    Time: 15:00-16:00
    Location: Nella and Leon Benoziyo Building for Biological Sciences
    Lecturer: Dr. Neta Sal-Man
    Organizer: Department of Biomolecular Sciences
    Contact: levana.ayvazo@weizmann.ac.il
    Abstract: Reported cases of diarrheal samples exhibiting co-infections or multiple infecti ... Read more Reported cases of diarrheal samples exhibiting co-infections or multiple infections with two or more infectious agents are on the rise, likely due to advances in bacterial diagnostic techniques. Our work aims to decode the communication between bacterial pathogens within the digestive system and investigates whether they compete or cooperate. Additionally, we examine how commensal strains of the microbiome intercept this communication through specific metabolites
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    Microbiota and cancer treatment - an ecological journey

    Date:
    29
    Thursday
    June
    2023
    Lecture / Seminar
    Time: 14:00-15:00
    Location: Max and Lillian Candiotty Building
    Lecturer: Dr. Ben Boursi
    Organizer: Dwek Institute for Cancer Therapy Research
    Contact: michal.av@weizmann.ac.il
    Details: Meeting URL: https://weizmann.zoom.us/j/5065402023?pwd=a3Z6KzRCU0xJaUFoM2Y5emZwZ ... Read more Meeting URL: https://weizmann.zoom.us/j/5065402023?pwd=a3Z6KzRCU0xJaUFoM2Y5emZwZm1oZz09
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    Microbiome Metabolites: Syntheses and Surprises

    Date:
    06
    Tuesday
    June
    2023
    Lecture / Seminar
    Time: 14:00-15:00
    Location: Gerhard M.J. Schmidt Lecture Hall
    Lecturer: Prof. Karl Gademann
    Organizer: Department of Chemical and Structural Biology
    Contact: nicole.dorfman@weizmann.ac.il

    Special guest seminar

    Date:
    04
    Sunday
    June
    2023
    Lecture / Seminar
    Time: 00:00
    Title: T cell memory, metabolism and the microbiome
    Location: Max and Lillian Candiotty Building
    Lecturer: Professor Sammy Bedoui
    Organizer: Department of Immunology and Regenerative Biology
    Contact: ronen.alon@weizmann.ac.il

    A meta'omics perspective on the functional potential and regulation of metabolic activity in the global ocean microbiome

    Date:
    31
    Tuesday
    January
    2023
    Lecture / Seminar
    Time: 11:30-12:30
    Location: Nella and Leon Benoziyo Building for Biological Sciences
    Lecturer: Prof. Shinichi Sunagawa
    Organizer: Department of Plant and Environmental Sciences
    Contact: david.zeevi@weizmann.ac.il
    Details: Host: Dr. David Zeevi