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All Publications

  • Plasmid-encoded toxin defence mediates mutualistic microbial interactions

    Authors: Moraïs S., Mazor M., Tovar-Herrera O., Zehavi T., Zorea A., Ifrach M., Bogumil D., Brandis A., Walter J., Elia N., Gur E. & Mizrahi I. (2024), Nature Microbiology. 9, p. 108-119

  • Competitive fungal commensalism mitigates candidiasis pathology

    Authors: Sekeresova Kralova J., Donic C., Dassa B., Livyatan I., Jansen P. M., Ben-Dor S., Fidel L., Trzebanski S., Narunsky-Haziza L., Asraf O., Brenner O., Dafni H., Jona G., Boura-Halfon S., Stettner N., Segal E., Brunke S., Pilpel Y., Straussman R., Zeevi D., Bacher P., Hube B., Shlezinger N. & Jung S. (2024), Journal of Experimental Medicine. 221, 5, e20231686

  • Embracing cancer complexity: Hallmarks of systemic disease

    Authors: Swanton C., Bernard E., Abbosh C., André F., Auwerx J., Balmain A., Bar-Sagi D., Bernards R., Bullman S., DeGregori J., Elliott C., Erez A., Evan G., Febbraio M. A., Hidalgo A., Jamal-Hanjani M., Joyce J. A., Kaiser M., Lamia K., Locasale J. W., Loi S., Malanchi I., Merad M., Musgrave K., Patel K. J., Quezada S., Wargo J. A., Weeraratna A., White E., Winkler F., Wood J. N., Vousden K. H. & Hanahan D. (2024), Cell. 187, 7, p. 1589-1616

  • Complement(ing) the microbiome in infants through breastmilk

    Authors: Nobs S. P. & Elinav E. (2024), Cell Research.

  • Integrated Metabolomics and Proteomics of Symptomatic and Early Presymptomatic States of Colitis

    Authors: Shimshoni E., Solomonov I., Sagi I. & Ghini V. (2024), Journal of Proteome Research. 23, 4, p. 1420-1432

  • Melanoma and microbiota: Current understanding and future directions

    Authors: Routy B., Jackson T., Mählmann L., Baumgartner C. K., Blaser M., Byrd A., Corvaia N., Couts K., Davar D., Derosa L., Hang H. C., Hospers G., Isaksen M., Kroemer G., Malard F., McCoy K. D., Meisel M., Pal S., Ronai Z., Segal E., Sepich-Poore G. D., Shaikh F., Sweis R. F., Trinchieri G., van den Brink M., Weersma R. K., Whiteson K., Zhao L., McQuade J., Zarour H. & Zitvogel L. (2024), Cancer Cell. 42, 1, p. 16-34

  • Fine-tuning the gut ecosystem: the current landscape and outlook of artificial microbiome therapeutics

    Authors: Porcari S., Fusco W., Spivak I., Fiorani M., Gasbarrini A., Elinav E., Cammarota G. & Ianiro G. (2024), The Lancet Gastroenterology and Hepatology. 9, 5, p. 460-475

  • Bacterial SNPs in the human gut microbiome associate with host BMI

    Authors: Zahavi L., Lavon A., Reicher L., Shoer S., Godneva A., Leviatan S., Rein M., Weissbrod O., Weinberger A. & Segal E. (2023), Nature Medicine. 29, 11, p. 2785-2792

  • Microbiome-phage interactions in inflammatory bowel disease

    Authors: Federici S., Kviatcovsky D., Valdés-Mas R. & Elinav E. (2023), Clinical Microbiology and Infection. 29, 6, p. 682-688

  • TET2 and TET3 loss disrupts small intestine differentiation and homeostasis

    Authors: Ansari I., Solé-Boldo L., Ridnik M., Gutekunst J., Gilliam O., Korshko M., Liwinski T., Jickeli B., Weinberg-Corem N., Shoshkes-Carmel M., Pikarsky E., Elinav E., Lyko F. & Bergman Y. (2023), Nature Communications. 14, 1, 4005

  • A non-antibiotic-disrupted gut microbiome is associated with clinical responses to CD19-CAR-T cell cancer immunotherapy

    Authors: Stein-Thoeringer C. K., Saini N. Y., Zamir E., Blumenberg V., Schubert M. L., Mor U., Fante M. A., Schmidt S., Hayase E., Hayase T., Rohrbach R., Chang C. C., McDaniel L., Flores I., Gaiser R., Edinger M., Wolff D., Heidenreich M., Strati P., Nair R., Chihara D., Fayad L. E., Ahmed S., Iyer S. P., Steiner R. E., Jain P., Nastoupil L. J., Westin J., Arora R., Wang M. L., Turner J., Menges M., Hidalgo-Vargas M., Reid K., Dreger P., Schmitt A., Müller-Tidow C., Locke F. L., Davila M. L., Champlin R. E., Flowers C. R., Shpall E. J., Poeck H., Neelapu S. S., Schmitt M., Subklewe M., Jain M. D., Jenq R. R. & Elinav E. (2023), Nature Medicine. 29, 4, p. 906-916

  • Dietary fibers & immunity-more than meets the eye

    Authors: Cohen Y. & Elinav E. (2023),

  • Microbiota-dependent and -independent postnatal development of salivary immunity

    Authors: Zubeidat K., Jaber Y., Saba Y., Barel O., Naamneh R., Netanely Y., Horev Y., Eli-berchoer L., Shhadeh A., Yosef O., Arbib E., Betser-Cohen G., Nadler C., Shapiro H., Elinav E., Aframian D. J., Wilensky A. & Hovav A. (2023), Cell reports (Cambridge). 42, 1, 111981

  • Impact of caloric restriction on the gut microbiota

    Authors: Kern L., Kviatcovsky D., He Y. & Elinav E. (2023), Current Opinion in Microbiology. 73, 102287

  • Utilization of the microbiome in personalized medicine

    Authors: Ratiner K., Ciocan D., Abdeen S. K. & Elinav E. (2023), Nature Reviews Microbiology.

  • Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

    Authors: Kotsiliti E., Leone V., Schuehle S., Govaere O., Li H., Wolf M. J., Horvatic H., Bierwirth S., Hundertmark J., Inverso D., Zizmare L., Sarusi-Portuguez A., Gupta R., O'Connor T., Giannou A. D., Shiri A. M., Schlesinger Y., Beccaria M. G., Rennert C., Pfister D., Öllinger R., Gadjalova I., Ramadori P., Rahbari M., Rahbari N., Healy M. E., Fernández-Vaquero M., Yahoo N., Janzen J., Singh I., Fan C., Liu X., Rau M., Feuchtenberger M., Schwaneck E., Wallace S. J., Cockell S., Wilson-Kanamori J., Ramachandran P., Kho C., Kendall T. J., Leblond A. L., Keppler S. J., Bielecki P., Steiger K., Hofmann M., Rippe K., Zitzelsberger H., Weber A., Malek N., Luedde T., Vucur M., Augustin H. G., Flavell R., Parnas O., Rad R., Pabst O., Henderson N. C., Huber S., Macpherson A., Knolle P., Claassen M., Geier A., Trautwein C., Unger K., Elinav E., Waisman A., Abdullah Z., Haller D., Tacke F., Anstee Q. M. & Heikenwalder M. (2023), Journal of Hepatology. 79, 2, p. 296-313

  • Engineering bacteria to modulate host metabolism

    Authors: Ciocan D. & Elinav E. (2023), Acta Physiologica. 238, 3, e14001

  • Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

    Authors: Kennedy K. M., de Goffau M. C., Perez-Muñoz M. E., Arrieta M., Bäckhed F., Bork P., Braun T., Bushman F. D., Dore J., de Vos W. M., Earl A. M., Eisen J. A., Elovitz M. A., Ganal-Vonarburg S. C., Gänzle M. G., Garrett W. S., Hall L. J., Hornef M. W., Huttenhower C., Konnikova L., Lebeer S., Macpherson A. J., Massey R. C., McHardy A. C., Koren O., Lawley T. D., Ley R. E., O'Mahony L., O'Toole P. W., Pamer E. G., Parkhill J., Raes J., Rattei T., Salonen A., Segal E., Segata N., Shanahan F., Sloboda D. M., Smith G. C. S., Sokol H., Spector T. D., Surette M. G., Tannock G. W., Walker A. W., Yassour M. & Walter J. (2023), Nature. 613, 7945, p. 639-649

  • Impact of dietary interventions on pre-diabetic oral and gut microbiome, metabolites and cytokines

    Authors: Shoer S., Shilo S., Godneva A., Ben-Yacov O., Rein M., Wolf B. C., Lotan-Pompan M., Bar N., Weiss E. I., Houri-Haddad Y., Pilpel Y., Weinberger A. & Segal E. (2023), Nature Communications. 14, 5384

  • Daily turnover of active giant virus infection during algal blooms revealed by single-cell transcriptomics

    Authors: Hevroni G., Vincent F., Ku C., Sheyn U. & Vardi A. (2023), Science advances. 9, 41, eadf7971

  • Gut microbiome modulates the effects of a personalised postprandial-targeting (PPT) diet on cardiometabolic markers: a diet intervention in pre-diabetes

    Authors: Ben-Yacov O., Godneva A., Rein M., Shilo S., Lotan-Pompan M., Weinberger A. & Segal E. (2023), Gut. 72, 8, p. 1486-1496

  • CAR-T Cell Therapy and the Gut Microbiota

    Authors: Asokan S., Cullin N., Stein-Thoeringer C. K. & Elinav E. (2023), Cancers. 15, 3, 794

  • Tissue-specific macrophage immunometabolism

    Authors: Ben-Arosh H. & Avraham R. (2023), Current Opinion in Immunology. 84, 102369

  • Immunometabolism at the crossroads of obesity and cancer—a Keystone Symposia report

    Authors: Cable J., Rathmell J. C., Pearce E. L., Ho P. C., Haigis M. C., Mamedov M. R., Wu M. J., Kaech S. M., Lynch L., Febbraio M. A., Bapat S. P., Hong H. S., Zou W., Belkaid Y., Sullivan Z. A., Keller A., Wculek S. K., Green D. R., Postic C., Amit I., Benitah S. A., Jones R. G., Reina-Campos M., Torres S. V., Beyaz S., Brennan D., O'Neill L. A., Perry R. J. & Brenner D. (2023), Annals of the New York Academy of Sciences. 1523, 1, p. 38-50

  • Plant and microbial sciences as key drivers in the development of metabolomics research

    Authors: Aharoni A., Goodacre R. & Fernie A. R. (2023), Proceedings of the National Academy of Sciences - PNAS. 120, 12, e221738312

  • Circadian regulation of liver function: from molecular mechanisms to disease pathophysiology

    Authors: Bolshette N., Ibrahim H., Reinke H. & Asher G. (2023), Nature Reviews Gastroenterology and Hepatology. 20, 11, p. 695-707

  • Viral infection switches the balance between bacterial and eukaryotic recyclers of organic matter during coccolithophore blooms

    Authors: Vincent F., Gralka M., Schleyer G., Schatz D., Cabrera-Brufau M., Kuhlisch C., Sichert A., Vidal-Melgosa S., Mayers K., Barak-Gavish N., Flores J. M., Masdeu-Navarro M., Egge J. K., Larsen A., Hehemann J., Marrasé C., Simó R., Cordero O. X. & Vardi A. (2023), Nature Communications. 14, 510

  • Fungi and cancer

    Authors: Saftien A., Puschhof J. & Elinav E. (2023), Gut. 72, 7, p. 1410-1425

  • Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn's disease, and celiac disease

    Authors: Braun T., Sosnovski K. E., Amir A., BenShoshan M., VanDussen K. L., Karns R., Levhar N., Abbas-Egbariya H., Hadar R., Efroni G., Castel D., Avivi C., Rosen M. J., Grifiths A. M., Walters T. D., Mack D. R., Boyle B. M., Ali S. A., Moore S. R., Schirmer M., Xavier R. J., Kugathasan S., Jegga A. G., Weiss B., Mayer C., Barshack I., Ben-Horin S., Ulitsky I., Beucher A., Ferrer J., Hyams J. S., Denson L. A. & Haberman Y. (2023), JCI Insight. 8, 14, e170181

  • Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation

    Authors: Zheng D., Mohapatra G., Kern L., He Y., Shmueli M. D., Valdés-Mas R., Kolodziejczyk A. A., Próchnicki T., Vasconcelos M. B., Schorr L., Hertel F., Lee Y. S., Rufino M. C., Ceddaha E., Shimshy S., Hodgetts R. J., Dori-Bachash M., Kleimeyer C., Goldenberg K., Heinemann M., Stettner N., Harmelin A., Shapiro H., Puschhof J., Chen M., Flavell R. A., Latz E., Merbl Y., Abdeen S. K. & Elinav E. (2023), Nature Immunology. 24, 4, p. 585-594

  • Phage-display immunoprecipitation sequencing of the antibody epitope repertoire in inflammatory bowel disease reveals distinct antibody signatures

    Authors: Bourgonje A. R., Andreu-Sánchez S., Vogl T., Hu S., Vich Vila A., Gacesa R., Leviatan S., Kurilshikov A., Klompus S., Kalka I. N., van Dullemen H. M., Weinberger A., Visschedijk M. C., Festen E. A., Faber K. N., Wijmenga C., Dijkstra G., Segal E., Fu J., Zhernakova A. & Weersma R. K. (2023), Immunity. 56, 6, p. 1393-1409.e6

  • Blood coagulation and beyond: Position paper from the Fourth Maastricht Consensus Conference on Thrombosis

    Authors: Akbulut A. C., Arisz R. A., Baaten C. C., Baidildinova G., Barakzie A., Bauersachs R., Berg J. t., van den Broek W. W., Boer H. C., Bonifay A., Bröker V., Buka R. J., Cate H. t., Cate-Hoek A. J., Cointe S., Luca C. D., Simone I. D., Diaz R. V., Dignat-George F., Freson K., Gazzaniga G., van Gorp E. C., Habibi A., Henskens Y. M., Iding A. F., Khan A., Koenderink G. H., Konkoth A., Lacroix R., Lahiri T., Lam W., Lamerton R. E., Lorusso R., Luo Q., Maas C., Mccarty O. J., van der Meijden P. E., Meijers J. C., Mohapatra A. K., Nevo N., Robles A. P., Poncelet P., Reinhardt C., Ruf W., Saraswat R., Schönichen C., Schutgens R., Simioni P., Spada S., Spronk H. M., Tazhibayeva K., Thachil J., Vallier L., Veninga A., Verhamme P., Visser C., Watson S. P., Wenzel P., Willems R. A., Willers A., Zhang P., Zifkos K. & Zonneveld A. J. v. (2023), Thrombosis and Haemostasis. 123, 8, p. 808-839

  • Small Intestinal Microbiota Oscillations, Host Effects and Regulation—A Zoom into Three Key Effector Molecules

    Authors: Ratiner K., Fachler-Sharp T. & Elinav E. (2023), Biology (Basel, Switzerland). 12, 1, 142

  • Lactation-associated macrophages exist in murine mammary tissue and human milk

    Authors: Cansever D., Petrova E., Krishnarajah S., Mussak C., Welsh C. A., Mildenberger W., Mulder K., Kreiner V., Roussel E., Stifter S. A., Andreadou M., Zwicky P., Jurado N. P., Rehrauer H., Tan G., Liu Z., Blériot C., Ronchi F., Macpherson A. J., Ginhoux F., Natalucci G., Becher B. & Greter M. (2023), Nature Immunology. 24, 7, p. 1098-1109

  • Human microbiome research: Growing pains and future promises

    Authors: Puschhof J. & Elinav E. (2023), PLoS Biology. 21, 3, e3002053

  • A microbial workout

    Authors: Kviatcovsky D. & Elinav E. (2023),

  • TRAF3 suppression encourages B cell recruitment and prolongs survival of microbiome-intact mice with ovarian cancer

    Authors: Zorea J., Motro Y., Mazor R. D., Carmi Y. K., Shulman Z., Mahajna J., Moran-Gilad J. & Elkabets M. (2023), Journal of Experimental and Clinical Cancer Research. 42, 107

  • Short-term dietary changes can result in mucosal and systemic immune depression

    Authors: Siracusa F., Schaltenberg N., Kumar Y., Lesker T. R., Steglich B., Liwinski T., Cortesi F., Frommann L., Diercks B. P., Bönisch F., Fischer A. W., Scognamiglio P., Pauly M. J., Casar C., Cohen Y., Pelczar P., Agalioti T., Delfs F., Worthmann A., Wahib R., Jagemann B., Mittrücker H. W., Kretz O., Guse A. H., Izbicki J. R., Lassen K. G., Strowig T., Schweizer M., Villablanca E. J., Elinav E., Huber S., Heeren J. & Gagliani N. (2023), Nature Immunology. 24, 9, p. 1473-1486

  • Diversity of the Pacific Ocean coral reef microbiome

    Authors: Galand P. E., Ruscheweyh H. J., Salazar G., Hochart C., Henry N., Hume B. C., Oliveira P. H., Perdereau A., Labadie K., Belser C., Boissin E., Romac S., Poulain J., Bourdin G., Iwankow G., Moulin C., Armstrong E. J., Paz-García D. A., Ziegler M., Agostini S., Banaigs B., Boss E., Bowler C., de Vargas C., Douville E., Flores M., Forcioli D., Furla P., Gilson E., Lombard F., Pesant S., Reynaud S., Thomas O. P., Troublé R., Zoccola D., Voolstra C. R., Thurber R. V., Sunagawa S., Wincker P., Allemand D. & Planes S. (2023), Nature Communications. 14, 3039

  • Calcium carbonate mineralization is essential for biofilm formation and lung colonization

    Authors: Cohen-Cymberknoh M., Kolodkin-Gal D., Keren-Paz A., Peretz S., Brumfeld V., Kapishnikov S., Suissa R., Shteinberg M., McLeod D., Maan H., Patrauchan M., Zamir G., Kerem E. & Kolodkin-Gal I. (2022), iScience. 25, 5, 104234

  • An expanded reference map of the human gut microbiome reveals hundreds of previously unknown species

    Authors: Leviatan S., Shoer S., Rothschild D., Gorodetski M. & Segal E. (2022), Nature Communications. 13, 3863

  • Urbanization comprehensively impairs biological rhythms in coral holobionts

    Authors: Rosenberg Y., Simon-Blecher N., Lalzar M., Yam R., Shemesh A., Alon S., Perna G., Cardenas A., Voolstra C. R., Miller D. J. & Levy O. (2022), Global Change Biology. 28, 10

  • Cancer microbiome

    Authors: Zitvogel L., Straussman R., Sepich-Poore G. D., Knight R., Iliev I. D., Sears C. L., Bullman S., Jobin C. & Zarour H. M. (2022), Cancer Cell. 40, 12, p. 1443-1447

  • Systemic antibody responses against human microbiota flagellins are overrepresented in chronic fatigue syndrome patients

    Authors: Vogl T., Kalka I. N., Klompus S., Leviatan S., Weinberger A. & Segal E. (2022), Science advances. 8, 38, eabq2422

  • Antibody signatures in inflammatory bowel disease: current developments and future applications

    Authors: Bourgonje A. R., Vogl T., Segal E. & Weersma R. K. (2022), Trends in Molecular Medicine. 28, 8, p. 693-705

  • Effects of personalized diets by prediction of glycemic responses on glycemic control and metabolic health in newly diagnosed T2DM: a randomized dietary intervention pilot trial

    Authors: Rein M., Ben-Yacov O., Godneva A., Shilo S., Zmora N., Kolobkov D., Cohen-Dolev N., Wolf B., Kosower N., Lotan-Pompan M., Weinberger A., Halpern Z., Zelber-Sagi S., Elinav E. & Segal E. (2022), BMC Medicine. 20, 56

  • An Integrated View of Diatom Interactions

    Authors: Vincent F. & Bowler C. (2022), The Molecular Life of Diatoms. p. 59-86

  • Denitrification in foraminifera has an ancient origin and is complemented by associated bacteria

    Authors: Woehle C., Roy A. S., Glock N., Michels J., Wein T., Weissenbach J., Romero D., Hiebenthal C., Gorb S. N., Schonfeld J. & Dagan T. (2022), Proceedings of the National Academy of Sciences. 119, 25, e220019811

  • BREAst Cancer Personalised NuTrition (BREACPNT): dietary intervention in breast cancer survivors treated with endocrine therapy – a protocol for a randomised clinical trial

    Authors: Rein M. S., Dadiani M., Godneva A., Bakalenik-Gavry M., Morzaev-Sulzbach D., Vachnish Y., Kolobkov D., Lotan-Pompan m., Weinberger A., Segal E. & Gal-Yam E. N. (2022), BMJ Open. 12, 11, e062498

  • Prediction of Personal Glycemic Responses to Food for Individuals With Type 1 Diabetes Through Integration of Clinical and Microbial Data

    Authors: Shilo S., Godneva A., Rachmiel M., Korem T., Kolobkov D., Karady T., Bar N., Wolf B. C., Glantz-Gashai Y., Cohen M., Zuckerman Levin N., Shehadeh N., Gruber N., Levran N., Koren S., Weinberger A., Pinhas-Hamiel O. & Segal E. (2022), Diabetes Care. 45, 3, p. 502-511

  • Mechanisms of immune activation and regulation: lessons from melanoma

    Authors: Kalaora S., Nagler A., Wargo J. A. & Samuels Y. (2022), Nature reviews. Cancer. 22, 4, p. 195-207

  • Use of Faecal Transplantation with a Novel Diet for Mild to Moderate Active Ulcerative Colitis: The CRAFT UC Randomised Controlled Trial

    Authors: Sarbagili Shabat C., Scaldaferri F., Zittan E., Hirsch A., Mentella M. C., Musca T., Cohen N. A., Ron Y., Fliss Isakov N., Pfeffer J., Yaakov M., Fanali C., Turchini L., Masucci L., Quaranta G., Kolonimos N., Godneva A., Weinberger A., Kopylov U., Levine A. & Maharshak N. (2022), Journal of Crohn's and Colitis. 16, 3, p. 369-378

  • Resolving the conflict between antibiotic production and rapid growth by recognition of peptidoglycan of susceptible competitors

    Authors: Maan H., Itkin M., Malitsky S., Friedman J. & Kolodkin-Gal I. (2022), Nature Communications. 13, 1, 431

  • Phenotypic correlates of the working dog microbiome

    Authors: Craddock H. A., Godneva A., Rothschild D., Motro Y., Grinstein D., Lotem-Michaeli Y., Narkiss T., Segal E. & Moran-Gilad J. (2022), npj Biofilms and Microbiomes. 8, 66

  • Glucosylated nanoparticles for the oral delivery of antibiotics to the proximal small intestine protect mice from gut dysbiosis

    Authors: Zhang G., Wang Q., Tao W., Jiang W., Elinav E., Wang Y. & Zhu S. (2022), Nature Biomedical Engineering. 6, p. 867-881

  • Smoking-induced microbial dysbiosis in health and disease

    Authors: Shapiro H., Goldenberg K., Ratiner K. & Elinav E. (2022), Clinical science (1979). 136, 18, p. 1371-1387

  • A RORγt+ cell instructs gut microbiota-specific Treg cell differentiation

    Authors: Kedmi R., Najar T. A., Mesa K. R., Grayson A., Kroehling L., Hao Y., Hao S., Pokrovskii M., Xu M., Talbot J., Germino J., Wang J., Lareau C. A., Satpathy A. T., Anderson M. S., Laufer T. M., Aifantis I., Bartleson J. M., Allen P. M., Paidassi H., Gardner J. M., Stoeckius M. & Littman D. R. (2022), Nature. 610, 7933, p. 737-743

  • Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance

    Authors: Suez J., Cohen Y., Valdés-Mas R., Mor U., Dori-Bachash M., Federici S., Zmora N., Leshem A., Heinemann M., Linevsky R., Zur M., Ben-Zeev Brik R., Bukimer A., Eliyahu-Miller S., Metz A., Fischbein R., Sharov O., Malitsky S., Itkin M., Stettner N., Harmelin A., Shapiro H., Stein-Thoeringer C. K., Segal E. & Elinav E. (2022), Cell. 185, 18, p. 3307-3328.e19

  • Microbiome and metabolome features of the cardiometabolic disease spectrum

    Authors: Fromentin S., Forslund S. K., Chechi K., Bar N. & Segal E. (2022), Nature Medicine. 28, 2, p. 303-314

  • Compartmentalization of the host microbiome: how tumor microbiota shapes checkpoint immunotherapy outcome and offers therapeutic prospects

    Authors: Boesch M., Horvath L., Baty F., Pircher A., Wolf D., Spahn S., Straussman R., Tilg H. & Brutsche M. H. (2022), Journal for ImmunoTherapy of Cancer. 10, e005401

  • Precision Nutrition for Type 2 Diabetes

    Authors: Ben-Yacov O. & Rein M. (2022), Precision Medicine in Diabetes. p. 233-249

  • Macrophage metabolism in the intestine is compartment specific and regulated by the microbiota

    Authors: Scott N. A., Lawson M. A., Hodgetts R. J., Le Gall G., Hall L. J. & Mann E. R. (2022), Immunology. 166, 1, p. 138-152

  • The Gut Microbiome of Adults With Type 1 Diabetes and Its Association With the Host Glycemic Control

    Authors: Shilo S., Godneva A., Rachmiel M., Korem T., Bussi Y., Kolobkov D., Karady T., Bar N., Wolf B. C., Glantz-Gashai Y., Cohen M., Levin N. Z., Shehadeh N., Gruber N., Levran N., Koren S., Weinberger A., Pinhas-Hamiel O. & Segal E. (2022), Diabetes Care. 45, 3, p. 555-563

  • Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease

    Authors: Talmor-Barkan Y., Bar N., Shaul A. A., Shahaf N., Godneva A., Bussi Y., Lotan-Pompan M., Weinberger A., Shechter A., Chezar-Azerrad C., Arow Z., Hammer Y., Chechi K., Forslund S. K., Fromentin S., Dumas M., Ehrlich S. D., Pedersen O., Kornowski R. & Segal E. (2022), Nature Medicine. 28, 2, p. 295-302

  • Local and systemic effects of microbiome‐derived metabolites

    Authors: Spivak I., Fluhr L. & Elinav E. (2022), EMBO Reports. 23, 10, e55664

  • Loss-of-function SLC30A2 mutants are associated with gut dysbiosis and alterations in intestinal gene expression in preterm infants

    Authors: Kelleher S. L., Alam S., Rivera O. C., Barber-Zucker S., Zarivach R., Wagatsuma T., Kambe T., Soybel D. I., Wright J. & Lamendella R. (2022), Gut Microbes. 14, 1, 2014739

  • Metaproteome plasticity sheds light on the ecology of the rumen microbiome and its connection to host traits

    Authors: Sasson G., Morais S., Kokou F., Plate K., Trautwein-Schult A., Jami E., Bayer E., Becher D. & Mizrahi I. (2022), The ISME Journal.

  • Context-dependent differences in the functional responses of Lactobacillaceae strains to fermentable sugars

    Authors: Suissa R., Oved R., Maan H., Hadad U., Gilhar O., Meijler M. M., Koren O. & Kolodkin-Gal I. (2022), Frontiers in Microbiology. 13, 949932

  • Designer Liposomic Nanocarriers Are Effective Biofilm Eradicators

    Authors: Kluzek M., Oppenheimer-Shaanan Y., Dadosh T., Morandi M. I., Avinoam O., Raanan C., Goldsmith M., Goldberg R. & Klein J. (2022), ACS Nano. 16, 10, p. 15792-15804

  • Protozoa populations are ecosystem engineers that shape prokaryotic community structure and function of the rumen microbial ecosystem

    Authors: Solomon R., Wein T., Levy B., Eshed S., Dror R., Reiss V., Zehavi T., Furman O., Mizrahi I. & Jami E. (2022), The ISME Journal. 16, 4, p. 1187-1197

  • Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation

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  • The Microbiome Mediates Environmental Effects on Aging

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  • Skin Microbiome Compositional Changes in Atopic Dermatitis Accompany Dead Sea Climatotherapy

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  • The Immune System Computes the State of the Body: Crowd Wisdom, Machine Learning, and Immune Cell Reference Repertoires Help Manage Inflammation

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  • Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes

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  • Applying the handicap principle to biofilms: condition-dependent signalling in Bacillus subtilis microbial communities

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  • The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs

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  • Helminth-Based Product and the Microbiome of Mice with Lupus

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  • Carrying capacity and colonization dynamics of Curvibacter in the hydra host habitat

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  • HflXr, a homolog of a ribosome-splitting factor, mediates antibiotic resistance

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  • Loss of MicroRNA-21 Influences the Gut Microbiota, Causing Reduced Susceptibility in a Murine Model of Colitis

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  • Sequential BMP7/TGF-beta 1 signaling and microbiota instruct mucosal Langerhans cell differentiation

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  • Microbiome-Germline Interactions and Their Transgenerational Implications

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  • Bile acids in glucose metabolism in health and disease

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  • Role of the gut microbiota in nutrition and health

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  • A case study for late Archean and Proterozoic biogeochemical iron- and sulphur cycling in a modern habitatthe Arvadi Spring

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  • Temporal Stability of the Healthy Human Skin Microbiome Following Dead Sea Climatotherapy

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  • Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT

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  • Probiotics administration following sleeve gastrectomy surgery: a randomized double-blind trial

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  • Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner

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  • Towards utilization of the human genome and microbiome for personalized nutrition

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  • Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection

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  • Combining 16S rRNA gene variable regions enables high-resolution microbial community profiling

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  • Assembly of Synthetic Functional Cellulosomal Structures onto the Cell Surface of Lactobacillus plantarum, a Potent Member of the Gut Microbiome

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  • Spatial Reconstruction of Single Enterocytes Uncovers Broad Zonation along the Intestinal Villus Axis

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  • Sporulation capability and amylosome conservation among diverse human colonic and rumen isolates of the keystone starch-degrader Ruminococcus bromii

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  • The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses

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  • Host genetics and microbiome associations through the lens of genome wide association studies

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  • Microbiome facilitated pest resistance: potential problems and uses

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  • Translating microbiome futures

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  • High Levels of CO2 Induce Spoilage by Leuconostoc mesenteroides by Upregulating Dextran Synthesis Genes

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  • The anti-inflammatory IFITM genes ameliorate colitis and partially protect from tumorigenesis by changing immunity and microbiota

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  • Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features

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  • Sieving through gut models of colonization resistance

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  • Insights into microbial involvement in desert varnish formation retrieved from metagenomic analysis

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  • The path towards microbiome-based metabolite treatment

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  • Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation

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  • Inflammasomes and intestinal inflammation

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  • Citrobacter rodentium Subverts ATP Flux and Cholesterol Homeostasis in Intestinal Epithelial Cells In Vivo

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  • Microbiome, metabolites and host immunity

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  • Broad phylogeny and functionality of cellulosomal components in the bovine rumen microbiome

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  • How holobionts get sick-toward a unifying scheme of disease

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  • Irf4-dependent CD103(+) CD11b(+) dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileus

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  • Tuftsin-phosphorylcholine maintains normal gut microbiota in collagen induced arthritic mice

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  • The microbiome in anti-cancer therapy

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  • NFIL-trating the Host Circadian Rhythm-Microbes Fine-Tune the Epithelial Clock

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  • GAS6 is a key homeostatic immunological regulator of host-commensal interactions in the oral mucosa

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  • Involvement of a gut-retina axis in protection against dietary glycemia-induced age-related macular degeneration

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  • Origin-Dependent Variations in the Atmospheric Microbiome Community in Eastern Mediterranean Dust Storms

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  • Quinones are growth factors for the human gut microbiota

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  • Post-dieting weight gain: The role of persistent microbiome changes

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  • Dysbiosis and the immune system

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  • The gut microbiome and hypertension

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  • Metagenomic analysis reveals unusually high incidence of proteorhodopsin genes in the ultraoligotrophic Eastern Mediterranean Sea

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  • Impact of cystic fibrosis disease on archaea and bacteria composition of gut microbiota

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  • The remedy within: will the microbiome fulfill its therapeutic promise?

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  • The Role of the Immune System in Metabolic Health and Disease

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  • Microbiome at the Frontier of Personalized Medicine

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  • Computational prediction of regulatory, premature transcription termination in bacteria

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  • Bread Affects Clinical Parameters and Induces Gut Microbiome-Associated Personal Glycemic Responses

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  • Microbiome-modulated metabolites at the interface of host immunity

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  • Microglia development follows a stepwise program to regulate brain homeostasis

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  • Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling

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  • Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis

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  • Personalized Nutrition by Prediction of Glycemic Responses

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  • Unique organization of extracellular amylases into amylosomes in the resistant starch-utilizing human colonic firmicutes bacterium ruminococcus bromii

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  • Inflammasomes and the microbiota—partners in the preservation of mucosal homeostasis

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  • Time for food: The intimate interplay between nutrition, metabolism, and the circadian clock

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  • Guardians of the gut - murine intestinal macrophages and dendritic cells

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  • Functional phylotyping approach for assessing intraspecific diversity of Ruminococcus albus within the rumen microbiome

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  • Metagenomic cross-talk: The regulatory interplay between immunogenomics and the microbiome

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  • Artificial Sweeteners Induce Glucose Intolerance by Altering the Gut Microbiota: Editorial comment

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  • The interplay between the innate immune system and the microbiota

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  • Artificial sweeteners induce glucose intolerance by altering the gut microbiota

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  • A simple cage-autonomous method for the maintenance of the barrier status of germ-free mice during experimentation

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  • The fire within: Microbes inflame tumors

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  • Transkingdom control of microbiota diurnal oscillations promotes metabolic homeostasis

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  • NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion

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  • Biomass Utilization by Gut Microbiomes

    Authors: White B., Lamed R., Bayer E. & Flint H. (2014), Annual Review of Microbiology. 68, p. 279-296

  • An iron-containing dodecameric heptosyltransferase family modifies bacterial autotransporters in pathogenesis

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  • Zooplankton may serve as transmission vectors for viruses infecting algal blooms in the ocean

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  • Exploring new horizons in microbiome research

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  • Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation

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  • Role of the intestinal microbiome in liver disease

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  • High-resolution microbial community reconstruction by integrating short reads from multiple 16S rRNA regions

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  • Effect of metal oxide nanoparticles on microbial community structure and function in two different soil types

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  • The Intestinal Microbiota in Chronic Liver Disease

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  • In vitro microbiotic fermentation causes an extensive metabolite turnover of rye bran phytochemicals

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