Host innate immunity and bacterial commensals prevent fungal dysbiosis in Arabidopsis roots
Date:
Lecture / Seminar
Time: 11:30-12:30
Location: VIA ZOOM: https://weizmann.zoom.us/j/98989152393?pwd=a050Mm4rSlEwb2hLN1FiKy9oT24xdz09 Meeting ID: 989 8915 2393 Password: 002663
Lecturer: Prof. Stéphane Hacquard
Organizer: Department of Plant and Environmental Sciences
Details: Department of Plant-Microbe Interactions, Max Planck Institute
Abstract: Understanding how host–microbe homeostasis is controlled and maintained in pla ... Read more Understanding how host–microbe homeostasis is controlled and maintained in plant roots is key to enhance plant productivity. However, the factors that contribute to the maintenance of this equilibrium between plant roots and their multikingdom microbial communities remain largely unknown. Using a microbiota deconstruction-reconstruction approach in gnotobiotic plant systems with synthetic, yet representative communities of bacteria, fungi, and oomycetes, we observe a link between fungal assemblages/load in roots and plant health. We show that modulation of fungal abundance in roots is tightly controlled by a two-layer regulatory circuit involving the host innate immune system on one hand and bacterial root commensals on another hand. We also report that fungi with the most detrimental activities in mono-association experiments with the host are part of the core root mycobiome in nature. Our results shed a light into how host–microbe and microbe–microbe interactions act in concert to prevent fungal dysbiosis in roots, thereby promoting plant health and maintaining growth-promoting activities of multikingdom microbial consortia.Close abstract
