All Publications

  • Systematic Detection of Amino Acid Substitutions in Proteomes Reveals Mechanistic Basis of Ribosome Errors and Selection for Translation Fidelity

    Mordret E., Dahan O., Asraf O., Rak R., Yehonadav A., Barnabas G. D., Cox J., Geiger T., Lindner A. B. & Pilpel Y. (2019)
  • Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

    Jaitin D. A., Adlung L., Thaiss C. A., Weiner A., Li B., Descamps H., Lundgren P., Bleriot C., Liu Z., Deczkowska A., Keren-Shaul H., David E., Zmora N., Eldar S. M., Lubezky N., Shibolet O., Hill D. A., Lazar M. A., Colonna M., Ginhoux F., Shapiro H., Elinav E. & Amit I. (2019)
  • Spatial heterogeneity in the mammalian liver

    Ben-Moshe S. & Itzkovitz S. (2019)
  • Cooperativity between stromal cytokines drives the invasive migration of human breast cancer cells

    Elisha Y., Sagi Y., Klein G., Straussman R. & Geiger B. (2019)
  • No guts, no research glory

    Elinav E. (2019)
  • The mitochondrial intermembrane space-facing proteins Mcp2 and Tgl2 are involved in yeast lipid metabolism

    Odendall F., Backes S., Tatsuta T., Weill U., Schuldiner M., Langer T., Herrmann J. M., Rapaport D. & Dimmer K. S. (2019)
  • Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules

    Zviran A., Mor N., Rais Y., Gingold H., Peles S., Chomsky E., Viukov S., Buenrostro J. D., Scognamiglio R., Weinberger L., Manor Y. S., Krupalnik V., Zerbib M., Hezroni H., Jaitin D. A., Larastiaso D., Gilad S., Benjamin S., Gafni O., Mousa A., Ayyash M., Sheban D., Bayerl J., Aguilera-Castrejon A., Massarwa R., Maza I., Hanna S., Stelzer Y., Ulitsky I., Greenleaf W. J., Tanay A., Trumpp A., Amit I., Pilpel Y., Novershtern N. & Hanna J. H. (2019)
  • A niche-dependent myeloid transcriptome signature defines dormant myeloma cells

    Khoo W. H., Ledergor G., Weiner A., Roden D. L., Terry R. L., McDonald M. M., Chai R. C., De Veirman K., Owen K. L., Opperman K. S., Vandyke K., Clark J. R., Seckinger A., Kovacic N., Nguyen A., Mohanty S. T., Pettitt J. A., Xiao Y., Corr A. P., Seeliger C., Novotny M., Lasken R. S., Nguyen T., Oyajobi B. O., Aftab D., Swarbrick A., Parker B., Hewett D. R., Hose D., Vanderkerken K., Zannettino A. C. W., Amit I., Phan T. G. & Croucher P. (2019)
  • Widespread Utilization of Peptide Communication in Phages Infecting Soil and Pathogenic Bacteria

    Stokar-Avihail A., Tal N., Erez Z., Lopatina A. & Sorek R. (2019)
  • Potential roles of gut microbiome and metabolites in modulating ALS in mice

    Blacher E., Bashiardes S., Shapiro H., Rothschild D., Mor U., Dori-Bachash M., Kleimeyer C., Moresi C., Harnik Y., Zur M., Zabari M., Brik R. B., Kviatcovsky D., Zmora N., Cohen Y., Bar N., Levi I., Amar N., Mehlman T., Brandis A., Biton I., Kuperman Y., Tsoory M., Alfahel L., Harmelin A., Schwartz M., Israelson A., Arike L., Johansson M. E. V., Hansson G. C., Gotkine M., Segal E. & Elinav E. (2019)
  • Long Noncoding RNA MALAT1 Regulates Cancer Glucose Metabolism by Enhancing mTOR-Mediated Translation of TCF7L2

    Malakar P., Stein I., Saragovi A., Winkler R., Stern-Ginossar N., Berger M., Pikarsky E. & Karni R. (2019)
  • Sybil-Resilient Conductance-Based Community Growth

    Poupko O., Shahaf G., Shapiro E. & Talmon N. (2019)
  • MetaCell: analysis of single-cell RNA-seq data using K-nn graph partitions

    Baran Y., Bercovich A., Sebe-Pedros A., Lubling Y., Giladi A., Chomsky E., Meir Z., Hoichman M., Lifshitz A. & Tanay A. (2019)
  • The global mass and average rate of rubisco

    Bar-On Y. M. & Milo R. (2019)
  • The cancer microbiome

    Elinav E., Garrett W. S., Trinchieri G. & Wargo J. (2019)
  • A rhlI 5 ' UTR-Derived sRNA Regulates RhlR-Dependent Quorum Sensing in Pseudomonas aeruginosa

    Thomason M. K., Voichek M., Dar D., Addis V., Fitzgerald D., Gottesman S., Sorek R. & Greenberga E. P. (2019)
  • Evolthon: A community endeavor to evolve lab evolution

    Kaminski Strauss S., Schirman D., Jona G., Brooks A. N., Kunjapur A. M., Ba A. N. N., Flint A., Solt A., Mershin A., Dixit A., Yona A. H., Csorgo B., Busby B. P., Hennig B. P., Pal C., Schraivogel D., Schultz D., Wernick D. G., Agashe D., Levi D., Zabezhinsky D., Russ D., Sass E., Tamar E., Herz E., Levy E. D., Church G. M., Yelin I., Nachman I., Gerst J. E., Georgeson J. M., Adamala K. P., Steinmetz L. M., Ruebsam M., Ralser M., Klutstein M., Desai M. M., Walunjkar N., Yin N., Hefetz N. A., Jakimo N., Snitser O., Adini O., Kumar P., Smith R. S. H., Zeidan R., Hazan R., Rak R., Kishony R., Johnson S., Nouriel S., Vonesch S. C., Foster S., Dagan T., Wein T., Karydis T., Wannier T. M., Stiles T., Olin-Sandoval V., Mueller W. F., Bar-On Y. M., Dahan O. & Pilpel Y. (2019)
  • PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model

    Rosenzweig N., Dvir-Szternfeld R., Tsitsou-Kampeli A., Keren-Shaul H., Ben-Yehuda H., Weill-Raynal P., Cahalon L., Kertser A., Baruch K., Amit I., Weiner A. & Schwartz M. (2019)
  • Noise-precision tradeoff in predicting combinations of mutations and drugs

    Tendler A., Zimmer A., Mayo A. & Alon U. (2019)
  • Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas

    Farack L., Golan M., Egozi A., Dezorella N., Halpern K. B., Ben-Moshe S., Garzilli I., Toth B., Roitman L., Krizhanovsky V. & Itzkovitz S. (2019)
  • Infinite Assembly of Folded Proteins in Evolution, Disease, and Engineering

    Garcia-Seisdedos H., Villegas J. A. & Levy E. D. (2019)
  • Central dogma rates and the trade-off between precision and economy in gene expression

    Hausser J., Mayo A., Keren L. & Alon U. (2019)
  • Successful Brincidofovir Treatment of Metagenomics-detected Adenovirus Infection in a Severely Ill Signal Transducer and Activator of Transcription-1-deficient Patient

    Averbuch D., Safadi R., Dar D., Wolf D., Cherniak M., Sorek R. & Amit S. (2019)
  • Systematic interrogation of human promoters

    Weingarten-Gabbay S., Nir R., Lubliner S., Sharon E., Kalma Y., Weinberger A. & Segal E. (2019)
  • Revisiting Trade-offs between Rubisco Kinetic Parameters

    Flamholz A., Prywes N., Moran U., David D., Bar-On Y. M., Oltrogge L. M., Alves R., Savage D. & Milo R. (2019)
  • Coming together to define membrane contact sites

    Scorrano L., De Matteis M. A., Emr S., Giordano F., Hajnoczky G., Kornmann B., Lackner L. L., Levine T. P., Pellegrini L., Reinisch K., Rizzuto R., Simmen T., Stenmark H., Ungermann C. & Schuldiner M. (2019)
  • Overexpression of branched-chain amino acid aminotransferases rescues the growth defects of cells lacking the Barth syndrome-related gene TAZ1

    Antunes D., Chowdhury A., Aich A., Saladi S., Harpaz N., Stahl M., Schuldiner M., Herrmann J. M., Rehling P. & Rapaport D. (2019)
  • The role of the microbiome in NAFLD and NASH

    Kolodziejczyk A. A., Zheng D., Shibolet O. & Elinav E. (2019)
  • Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma

    Li H., van der Leun A. M., Yofe I., Lubling Y., Gelbard-Solodkin D., van Akkooi A. C. J., van den Braber M., Rozeman E. A., Haanen J. B. A. G., Blank C. U., Horlings H. M., David E., Baran Y., Bercovich A., Lifshitz A., Schumacher T. N., Tanay A. & Amit I. (2019)
  • Misincorporation signatures for detecting modifications in mRNA: Not as simple as it sounds

    Sas-Chen A. & Schwartz S. (2019)
  • The rationale and design of the personal diet study, a randomized clinical trial evaluating a personalized approach to weight loss in individuals with pre-diabetes and early-stage type 2 diabetes

    Popp C. J., St-Jules D. E., Hu L., Ganguzza L., Illiano P., Curran M., Li H., Schoenthaler A., Bergman M., Schmidt A. M., Segal E., Godneva A. & Sevick M. A. (2019)
  • Disease-causing mutations in subunits of OXPHOS complex I affect certain physical interactions

    Barshad G., Zlotnikov-Poznianski N., Gal L., Schuldiner M. & Mishmar D. (2019)
  • YeastRGB: comparing the abundance and localization of yeast proteins across cells and libraries

    Dubreuil B., Sass E., Nadav Y., Heidenreich M., Georgeson J. M., Weill U., Duan Y., Meurer M., Schuldiner M., Knop M. & Levy E. D. (2019)
  • Deciphering the "m6A Code" via Antibody-Independent Quantitative Profiling

    Garcia-Campos M. A., Edelheit S., Toth U., Safra M., Shachar R., Viukov S., Winkler R., Nir R., Lasman L., Brandis A., Hanna J. H., Rossmanith W. & Schwartz S. (2019)
  • c-Met activation leads to the establishment of a TGF beta-receptor regulatory network in bladder cancer progression

    Sim W. J., Iyengar P. V., Lama D., Lui S. K. L., Ng H. C., Haviv-Shapira L., Domany E., Kappei D., Tan T. Z., Saie A., Jaynes P. W., Verma C. S., Kumar A. P., Rouanne M., Ha H. K., Radulescu C., ten Dijke P., Eichhorn P. J. A. & Thiery J. P. (2019)
  • Cytotoxicity of 1-deoxysphingolipid unraveled by genome-wide genetic screens and lipidomics in Saccharomyces cerevisiae

    Haribowo A. G., Hannich J. T., Michel A. H., Megyeri M., Schuldiner M., Kornmann B. & Riezman H. (2019)
  • Generation of Human Primordial Germ Cell-like Cells at the Surface of Embryoid Bodies from Primed-pluripotency Induced Pluripotent Stem Cells

    Mitsunaga S., Shioda K., Isselbacher K. J., Hanna J. H. & Shioda T. (2019)
  • Pro-inflammatory Cytokines Alter the Immunopeptidome Landscape by Modulation of HLA-B Expression

    Javitt A., Barnea E., Kramer M. P., Wolf-Levy H., Levin Y., Admon A. & Merbl Y. (2019)
  • Structural variation in the gut microbiome associates with host health

    Zeevi D., Korem T., Godneva A., Bar N., Kurilshikov A., Lotan-Pompan M., Weinberger A., Fu J., Wijmenga C., Zhernakova A. & Segal E. (2019)
  • Dissecting splicing decisions and cell-to-cell variability with designed sequence libraries

    Mikl M., Hamburg A., Pilpel Y. & Segal E. (2019)
  • Transfer of the Septin Ring to Cytokinetic Remnants in ER Stress Directs Age-Sensitive Cell-Cycle Re-entry

    Chao J. T., Pina F., Onishi M., Cohen Y., Lai Y., Schuldiner M. & Niwa M. (2019)
  • High-throughput ultrastructure screening using electron microscopy and fluorescent barcoding

    Bykov Y. S., Cohen N., Gabrielli N., Manenschijn H., Welsch S., Chlanda P., Kukulski W., Patil K. R., Schuldiner M. & Briggs J. A. G. (2019)
  • Citrobacter rodentium induces rapid and unique metabolic and inflammatory responses in mice suffering from severe disease

    Carson D., Barry R., Hopkins E. G. D., Roumeliotis T., Garcia-Weber D., Mullineaux-Sanders C., Elinav E., Arrieumerlou C., Choudhary J. S. & Frankel G. (2019)
  • Dynamic lineage priming is driven via direct enhancer regulation by ERK

    Hamilton W. B., Mosesson Y., Monteiro R. S., Emdal K. B., Knudsen T. E., Francavilla C., Barkai N., Olsen J. V. & Brickman J. M. (2019)
  • Vaginal microbiome transplantation in women with intractable bacterial vaginosis

    Lev-Sagie A., Goldman-Wohl D., Cohen Y., Dori-Bachash M., Leshem A., Mor U., Strahilevitz J., Moses A. E., Shapiro H., Yagel S. & Elinav E. (2019)
  • MARS-seq2.0: an experimental and analytical pipeline for indexed sorting combined with single-cell RNA sequencing

    Keren-Shaul H., Kenigsberg E., Jaitin D. A., David E., Paul F., Tanay A. & Amit I. (2019)
  • Compartmentalized Synthesis of Triacylglycerol at the Inner Nuclear Membrane Regulates Nuclear Organization

    Barbosa A. D., Lim K., Mari M., Edgar J. R., Gal L., Sterk P., Jenkins B. J., Koulman A., Savage D. B., Schuldiner M., Reggiori F., Wigge P. A. & Siniossoglou S. (2019)
  • Global views of proteasome-mediated degradation by mass spectrometry

    Javitt A. & Merbl Y. (2019)
  • Plasmacytoid dendritic cells develop from Ly6D(+) lymphoid progenitors distinct from the myeloid lineage

    Dress R. J., Dutertre C., Giladi A., Schlitzer A., Low I., Shadan N. B., Tay A., Lum J., Kairi M. F. B. M., Hwang Y. Y., Becht E., Cheng Y., Chevrier M., Larbi A., Newell E. W., Amit I., Chen J. & Ginhoux F. (2019)
  • Deep microbial analysis of multiple placentas shows no evidence for a placental microbiome

    Kuperman A. A., Zimmerman A., Hamadia S., Ziv O., Gurevich V., Fichtman B., Gavert N., Straussman R., Rechnitzer H., Barzilay M., Shvalb S., Bornstein J., Ben-Shachar I., Yagel S., Haviv I. & Koren O. (2019)
  • The Transcriptome of Latent Human Cytomegalovirus

    Schwartz M. & Stern-Ginossar N. (2019)
  • Geometric description of self-interaction potential in symmetric protein complexes

    Empereur-Mot C., Garcia-Seisdedos H., Elad N., Dey S. & Levy E. D. (2019)
  • Embrace the fat when getting old

    Adlung L., Amit I. & Elinav E. (2019)
  • Predicting bacterial infection outcomes using single cell RNA-sequencing analysis of human immune cells

    Ben-Moshe N. B., Hen-Avivi S., Levitin N., Yehezkel D., Oosting M., Joosten L. A. B., Netea M. G. & Avraham R. (2019)
  • Genuine Personal Identifiers and Mutual Sureties for Sybil-Resilient Community Formation

    Shahaf G., Shapiro E. & Talmon N. (2019)
  • DC Respond to Cognate T Cell Interaction in the Antigen-Challenged Lymph Node

    Curato C., Bernshtein B., Zupancic E., Dufner A., Jaitin D., Giladi A., David E., Chappell-Maor L., Leshkowitz D., Knobeloch K., Amit I., Florindo H. F. & Jung S. (2019)
  • Diet-microbiota interactions and personalized nutrition

    Kolodziejczyk A. A., Zheng D. & Elinav E. (2019)
  • A Significant Expansion of Our Understanding of the Composition of the Human Microbiome

    Leviatan S. & Segal E. (2019)
  • Toward unrestricted use of public genomic data: Publication interests should not limit access to public data

    Amann R. I., Baichoo S., Blencowe B. J., Bork P., Borodovsky M., Brooksbank C., Chain P. S. G., Colwell R. R., Daffonchio D. G., Danchin A., de Lorenzo V., Dorrestein P. C., Finn R. D., Fraser C. M., Gilbert J. A., Hallam S. J., Hugenholtz P., Ioannidis J. P. A., Jansson J. K., Kim J. F., Klenk H., Klotz M. G., Knight R., Konstantinidis K. T., Kyrpides N. C., Mason C. E., McHardy A. C., Meyer F., Ouzounis C. A., Patrinos A. A. N., Podar M., Pollard K. S., Ravel J., Munoz A. R., Roberts R. J., Rossello-Mora R., Sansone S., Schloss P. D., Schriml L. M., Setubal J. C., Sorek R., Stevens R. L., Tiedje J. M., Turjanski A., Tyson G. W., Ussery D. W., Weinstock G. M., White O., Whitman W. B. & Xenarios I. (2019)
  • Microbiome diurnal rhythmicity and its impact on host physiology and disease risk

    Nobs S. P., Tuganbaev T. & Elinav E. (2019)
  • Cytokine sensitivity screening highlights BMP4 pathway signaling as a therapeutic opportunity in ER+ breast cancer

    Shee K., Jiang A., Varn F. S., Liu S., Traphagen N. A., Owens P., Ma C. X., Hoog J., Cheng C., Golub T. R., Straussman R. & Miller T. W. (2019)
  • Stem Cell-Derived Human Gametes: The Public Engagement Imperative

    Adashi E. Y., Cohen I. G., Hanna J. H., Surani A. M. & Hayashi K. (2019)
  • Regulation of CHD2 expression by the Chaserr long noncoding RNA gene is essential for viability

    Rom A., Melamed L., Gil N., Goldrich M. J., Kadir R., Golan M., Biton I., Perry R. B. & Ulitsky I. (2019)
  • Towards a quantitative view of the global ubiquity of biofilms

    Bar-On Y. M. & Milo R. (2019)
  • Stage-specific requirement for Mettl3-dependent m(6)A mRNA methylation during haematopoietic stem cell differentiation

    Lee H., Bao S., Qian Y., Geula S., Leslie J., Zhang C., Hanna J. H. & Ding L. (2019)
  • The pros, cons, and many unknowns of probiotics

    Suez J., Zmora N., Segal E. & Elinav E. (2019)
  • When Cultures Meet: The Landscape of "Social" Interactions between the Host and Its Indigenous Microbes

    Geva-Zatorsky N., Elinav E. & Pettersson S. (2019)
  • IL-23-producing IL-10Rα-deficient gut macrophages elicit an IL-22-driven proinflammatory epithelial cell response

    Bernshtein B., Curato C., Ioannou M., Thaiss C. A., Gross-Vered M., Kolesnikov M., Wang Q., David E., Chappell-Maor L., Harmelin A., Elinav E., Thakker P., Papayannopoulos V. & Jung S. (2019)
  • Fecal Microbial Transplantation and Its Potential Application in Cardiometabolic Syndrome

    Leshem A., Horesh N. & Elinav E. (2019)
  • m6A modification controls the innate immune response to infection by targeting type I interferons

    Winkler R., Gillis E., Lasman L., Safra M., Geula S., Soyris C., Nachshon A., Tai-Schmiedel J., Friedman N., Le-Trilling V. T. K., Trilling M., Mandelboim M., Hanna J. H., Schwartz S. & Stern-Ginossar N. (2019)
  • An iPSC-Derived Myeloid Lineage Model of Herpes Virus Latency and Reactivation

    Poole E., Huang C. J. Z., Forbester J., Shnayder M., Nachshon A., Kweider B., Basaj A., Smith D., Jackson S. E., Liu B., Shih J., Kiskin F. N., Roche K., Murphy E., Wills M. R., Morrell N. W., Dougan G., Stern-Ginossar N., Rana A. A. & Sinclair J. (2019)
  • You are what you eat: diet, health and the gut microbiota

    Zmora N., Suez J. & Elinav E. (2019)
  • Transmissible inflammation-induced colorectal cancer in inflammasome-deficient mice

    Hu B., Friedman G., Elinav E. & Flavell R. A. (2019)
  • The N-6-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy

    Dorn L. E., Lasman L., Chen J., Xu X., Hund T. J., Medvedovic M., Hanna J. H., van Berlo J. H. & Accornero F. (2019)
  • Corticosteroid signaling at the brain-immune interface impedes coping with severe psychological stress

    Kertser A., Baruch K., Deczkowska A., Weiner A., Croese T., Kenigsbuch M., Cooper I., Tsoory M., Ben-Hamo S., Amit I. & Schwartz M. (2019)
  • Translational Control in Virus-Infected Cells

    Stern-Ginossar N., Thompson S. R., Mathews M. B. & Mohr I. (2019)
  • Yeast ceramide synthases, Lag1 and Lac1, have distinct substrate specificity

    Megyeri M., Prasad R., Volpert G., Sliwa-Gonzalez A., Haribowo A. G., Aguilera-Romero A., Riezman H., Barral Y., Futerman A. H. & Schuldiner M. (2019)
  • Mutual interplay between IL-17-producing γδT (gamma delta T) cells and microbiota orchestrates oral mucosal homeostasis

    Wilharm A., Tabib Y., Nassar M., Reinhardt A., Mizraji G., Sandrock I., Heyman O., Barros-Martins J., Aizenbud Y., Khalaileh A., Eli-Berchoer L., Elinav E., Wilensky A., Foerster R., Bercovier H., Prinz I. & Hovav A. (2019)
  • Germline NPM1 mutations lead to altered rRNA 2 '-O-methylation and cause dyskeratosis congenita

    Nachmani D., Bothmer A. H., Grisendi S., Mele A., Bothmer D., Lee J. D., Monteleone E., Cheng K., Zhang Y., Bester A. C., Guzzetti A., Mitchell C. A., Mendez L. M., Pozdnyakova O., Sportoletti P., Martelli M., Vulliamy T. J., Safra M., Schwartz S., Luzzatto L., Bluteau O., Soulier J., Darnell R. B., Falini B., Dokal I., Ito K., Clohessy J. G. & Pandolfi P. P. (2019)
  • Protein Topology Prediction Algorithms Systematically Investigated in the Yeast Saccharomyces cerevisiae

    Weill U., Cohen N., Fadel A., Ben-Dor S. & Schuldiner M. (2019)
  • Cyclic GMP-AMP signalling protects bacteria against viral infection

    Cohen D., Melamed S., Millman A., Shulman G., Oppenheimer-Shaanan Y., Kacen A., Doron S., Amitai G. & Sorek R. (2019)
  • Accurate detection of m6A RNA modifications in native RNA sequences

    Liu H., Begik O., Lucas M. C., Ramirez J. M., Mason C. E., Wiener D., Schwartz S., Mattick J. S., Smith M. A. & Novoa E. M. (2019)
  • ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma

    Srivastava S., Nataraj N. B., Sekar A., Ghosh S., Bornstein C., Drago-Garcia D., Roth L., Romaniello D., Marrocco I., David E., Gilad Y., Lauriola M., Rotkopf R., Kimchi A., Haga Y., Tsutsumi Y., Mirabeau O., Surdez D., Zinovyev A., Delattre O., Kovar H., Amit I. & Yarden Y. (2019)
  • Evolution of intron splicing towards optimized gene expression is based on various Cis- and Trans-molecular mechanisms

    Frumkin I., Yofe I., Bar-Ziv R., Gurvich Y., Lu Y., Voichek Y., Towers R., Schirman D., Krebber H. & Pilpel Y. (2019)
  • Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes

    Riquelme E., Zhang Y., Zhang L., Montiel M., Zoltan M., Dong W., Quesada P., Sahin I., Chandra V., San Lucas A., Scheet P., Xu H., Hanash S. M., Feng L., Burks J. K., Do K., Peterson C. B., Nejman D., Tzeng C. D., Kim M. P., Sears C. L., Ajami N., Petrosino J., Wood L. D., Maitra A., Straussman R., Katz M., White J. R., Jenq R., Wargo J. & McAllister F. (2019)
  • Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations

    Rojo R., Raper A., Ozdemir D. D., Lefevre L., Grabert K., Wollscheid-Lengeling E., Bradford B., Caruso M., Gazova I., Sanchez A., Lisowski Z. M., Alves J., Molina-Gonzalez I., Davtyan H., Lodge R. J., Glover J. D., Wallace R., Munro D. A. D., David E., Amit I., Miron V. E., Priller J., Jenkins S. J., Hardingham G. E., Blurton-Jones M., Mabbott N. A., Summers K. M., Hohenstein P., Hume D. A. & Pridans C. (2019)
  • Universally non-immunogenic iPSCs

    Shani T. & Hanna J. H. (2019)
  • Sequence determinants of polyadenylation-mediated regulation

    Slutskin I. V., Weinberger A. & Segal E. (2019)
  • A transcriptome-wide analysis deciphers distinct roles of G1 cyclins in temporal organization of the yeast cell cycle

    Teufel L., Tummler K., Floettmann M., Herrmann A., Barkai N. & Klipp E. (2019)
  • Promethin Is a Conserved Seipin Partner Protein

    Castro I. G., Eisenberg-Bord M., Persiani E., Rochford J. J., Schuldiner M. & Bohnert M. (2019)
  • Single-Cell Analysis of Diverse Pathogen Responses Defines a Molecular Roadmap for Generating Antigen-Specific Immunity

    Blecher-Gonen R., Bost P., Hilligan K. L., David E., Salame T. M., Roussel E., Connor L. M., Mayer J. U., Halpern K. B., Toth B., Itzkovitz S., Schwikowski B., Ronchese F. & Amit I. (2019)
  • Assessment of GFP Tag Position on Protein Localization and Growth Fitness in Yeast

    Weill U., Krieger G., Avihou Z., Milo R., Schuldiner M. & Davidi D. (2019)
  • Transforming medicine with the microbiome

    Zmora N., Soffer E. & Elinav E. (2019)
  • The EXPANDER Integrated Platform for Transcriptome Analysis

    Hait T. A., Maron-Katz A., Sagir D., Amar D., Ulitsky I., Linhart C., Tanay A., Sharan R., Shiloh Y., Elkon R. & Shamir R. (2019)
  • Cell composition analysis of bulk genomics using single-cell data

    Frishberg A., Peshes-Yaloz N., Cohn O., Rosentul D., Steuerman Y., Valadarsky L., Yankovitz G., Mandelboim M., Iraqi F. A., Amit I., Mayo L., Bacharach E. & Gat-Viks I. (2019)
  • Global DNA methylation reflects spatial heterogeneity and molecular evolution of lung adenocarcinomas

    Dietz S., Lifshitz A., Kazdal D., Harms A., Endris V., Winter H., Stenzinger A., Warth A., Sill M., Tanay A. & Sueltmann H. (2019)
  • The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs

    Virtue A. T., McCright S. J., Wright J. M., Jimenez M. T., Mowel W. K., Kotzin J. J., Joannas L., Basavappa M. G., Spencer S. P., Clark M. L., Eisennagel S. H., Williams A., Levy M., Manne S., Henrickson S. E., Wherry E. J., Thaiss C. A., Elinav E. & Henao-Mejia J. (2019)
  • A secretion-enhancing cis regulatory targeting element (SECReTE) involved in mRNA localization and protein synthesis

    Cohen-Zontag O., Baez C., Lim L. Q. J., Olender T., Schirman D., Dahary D., Pilpel Y. & Gerst J. E. (2019)
  • Acid-Induced Downregulation of ASS1 Contributes to the Maintenance of Intracellular pH in Cancer

    Silberman A., Goldman O., Assayag O. B., Jacob A., Rabinovich S., Adler L., Lee J. S., Keshet R., Sarver A., Frug J., Stettner N., Galai S., Persi E., Halpern K. B., Zaltsman-Amir Y., Pode-Shakked B., Eilam R., Anikster Y., Nagamani S. C. S., Ulitsky I., Ruppin E. & Erez A. (2019)
  • Short tandem repeat stutter model inferred from direct measurement of in vitro stutter noise

    Raz O., Biezuner T., Spiro A., Amir S., Milo L., Titelman A., Onn A., Chapal-Ilani N., Tao L., Marx T., Feige U. & Shapiro E. (2019)
  • Prediction of ultra-high-order antibiotic combinations based on pairwise interactions

    Katzir I., Cokol M., Aldridge B. B. & Alon U. (2019)
  • Walk on the wildling side

    Nobs S. P. & Elinav E. (2019)
  • Continuum of Gene-Expression Profiles Provides Spatial Division of Labor within a Differentiated Cell Type

    Adler M., Kohanim Y. K., Tendler A., Mayo A. & Alon U. (2019)
  • Rho-Associated Coiled-Coil Kinase 1 Translocates to the Nucleus and Inhibits Human Cytomegalovirus Propagation

    Eliyahu E., Tirosh O., Dobesova M., Nachshon A., Schwartz M. & Stern-Ginossar N. (2019)
  • Peer power - A women's peer-mentoring program at the workplace:: example from the academia

    Levy-Tzedek S., Moran G. S., Alon U. & Sal-Man N. (2018)
  • Design principles of the paradoxical feedback between pancreatic alpha and beta cells

    Garzilli I. & Itzkovitz S. (2018)
  • Single cell dissection of plasma cell heterogeneity in symptomatic and asymptomatic myeloma

    Ledergor G., Weiner A., Zada M., Wang S., Cohen Y. C., Gatt M. E., Snir N., Magen H., Koren-Michowitz M., Herzog-Tzarfati K., Keren-Shaul H., Bornstein C., Rotkopf R., Yofe I., David E., Yellapantula V., Kay S., Salai M., Ben Yehuda D., Nagler A., Shvidel L., Orr-Urtreger A., Halpern K. B., Itzkovitz S., Landgren O., San-Miguel J., Paiva B., Keats J. J., Papaemmanuil E., Avivi I., Barbash G. I., Tanay A. & Amit I. (2018)
  • Microglial immune checkpoint mechanisms

    Deczkowska A., Amit I. & Schwartz M. (2018)
  • Revealing the cellular degradome by mass soectrometry analysis of proteasome-cleaved peptides

    Wolf-Levy H., Javitt A., Eisenberg-Lerner A., Kacenl A., Ulman A., Sheban D., Dassa B., Fishbain-Yoskovitz V., Carmona-Rivera C., Kramer M. P., Nudel N., Regevl I., Zahavi L., Elinger D., Kaplan M. J., Morgenstern D., Levin Y. & Merbl Y. (2018)
  • Environment dominates over host genetics in shaping human gut microbiota

    Rothschild D., Weissbrod O., Barkan E., Kurilshikov A., Korem T., Zeevi D., Costea P. I., Godneva A., Kalka I. N., Bar N., Shilo S., Lador D., Vila A. V., Zmora N., Pevsner-Fischer M., Israeli D., Kosower N., Malka G., Wolf B. C., Avnit-Sagi T., Lotan-Pompan M., Weinberger A., Halpern Z., Carmi S., Fu J., Wijmenga C., Zhernakova A., Elinav E. & Segal E. (2018)
  • Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies

    Haimon Z., Volaski A., Orthgiess J., Boura-Halfon S., Varol D., Shemer A., Yona S., Zuckerman B., David E., Chappell-Maor L., Bechmann I., Gericke M., Ulitsky I. & Jung S. (2018)
  • Hypercalcemia: a consultant's approach

    Auron A. & Alon U. S. (2018)
  • Contemporary Phage Biology: From Classic Models to New Insights

    Ofir G. & Sorek R. (2018)
  • Viruses cooperate to defeat bacteria

    Bernheim A. & Sorek R. (2018)
  • Endocytosis as a stabilizing mechanism for tissue homeostasis

    Adler M., Mayo A., Zhou X., Franklin R. A., Jacox J. B., Medzhitov R. & Alon U. (2018)
  • mRNA-seq whole transcriptome profiling of fresh frozen versus archived fixed tissues

    Ben-Moshe N. B., Gilad S., Perry G., Benjamin S., Balint-Lahat N., Pavlovsky A., Halperin S., Markus B., Yosepovich A., Barshack I., Gal-Yam E. N., Domany E., Kaufman B. & Dadiani M. (2018)
  • Loss of MicroRNA-21 Influences the Gut Microbiota, Causing Reduced Susceptibility in a Murine Model of Colitis

    Johnston D. G. W., Williams M. A., Thaiss C. A., Cabrera-Rubio R., Raverdeau M., McEntee C., Cotter P. D., Elinav E., O'Neill L. A. J. & Corr S. C. (2018)
  • Sequential BMP7/TGF-beta 1 signaling and microbiota instruct mucosal Langerhans cell differentiation

    Capucha T., Koren N., Nassar M., Heyman O., Nir T., Levy M., Zilberman-Schapira G., Zelentova K., Eli-Berchoer L., Zenke M., Hieronymus T., Wilensky A., Bercovier H., Elinav E., Clausen B. E. & Hovav A. (2018)
  • Salient experiences are represented by unique transcriptional signatures in the mouse brain

    Mukherjee D., Ignatowska-Jankowska B. M., Itskovits E., Gonzales B. J., Turm H., Izakson L., Haritan D., Bleistein N., Cohen C., Amit I., Shay T., Grueter B., Zaslaver A. & Citri A. (2018)
  • RAS Regulates the Transition from Naive to Primed Pluripotent Stem Cells

    Altshuler A., Verbuk M., Bhattacharya S., Abramovich I., Haklai R., Hanna J. H., Kloog Y., Gottlieb E. & Shalom-Feuerstein R. (2018)
  • DISARM is a widespread bacterial defence system with broad anti-phage activities

    Ofir G., Melamed S., Sberro H., Mukamel Z., Silverman S., Yaakov G., Doron S. & Sorek R. (2018)
  • Systematic mapping of contact sites reveals tethers and a function for the peroxisome-mitochondria contact

    Shai N., Yifrach E., van Roermund C. W. T., Cohen N., Bibi C., Ijlst L., Cavellini L., Meurisse J., Schuster R., Zada L., Mari M. C., Reggiori F. M., Hughes A. L., Escobar-Henriques M., Cohen M. M., Waterham H. R., Wanders R. J. A., Schuldiner M. & Zalckvar E. (2018)
  • Programming cells and tissues New toolkits of biological parts allow powerful cell programming by synthetic biologists

    Glass D. S. & Alon U. (2018)
  • PDB-wide identification of biological assemblies from conserved quaternary structure geometry

    Dey S., Ritchie D. W. & Levy E. D. (2018)
  • Natural genetic variation for expression of a SWEET transporter among wild species of Solanum lycopersicum (tomato) determines the hexose composition of ripening tomato fruit

    Shammai A., Petreikov M., Yeselson Y., Faigenboim A., Moy-Komemi M., Cohen S., Cohen D., Besaulov E., Efrati A., Houminer N., Bar M., Ast T., Schuldiner M., Klemens P. A. W., Neuhaus E., Baxter C. J., Rickett D., Bonnet J., White R., Giovannoni J. J., Levin I. & Schaffer A. (2018)
  • Meiotic Recombination: Genetics' Good Old Scalpel

    Slomka S. & Pilpel Y. (2018)
  • Noise-Seeded Developmental Pattern Formation in Filamentous Cyanobacteria

    Arbel-Goren R., Di Patti F., Fanelli D. & Stavans J. (2018)
  • Translational control of ERK signaling through miRNA/4EHP-directed silencing

    Jafarnejad S. M., Chapat C., Matta-Camacho E., Gelbart I. A., Hesketh G. G., Arguello M., Garzia A., Kim S., Attig J., Shapiro M., Morita M., Khoutorsky A., Alain T., Christos G. G., Stern-Ginossar N., Tuschl T., Gingras A., Duchaine T. F. & Sonenberg N. (2018)
  • The biomass distribution on Earth

    Bar-On Y. M., Phillips R. & Milo R. (2018)
  • An ER surface retrieval pathway safeguards the import of mitochondrial membrane proteins in yeast

    Hansen K. G., Aviram N., Laborenz J., Bibi C., Meyer M., Spang A., Schuldiner M. & Herrmann J. M. (2018)
  • Variants in PUS7 Cause Intellectual Disability with Speech Delay, Microcephaly, Short Stature, and Aggressive Behavior

    De Brouwer A. P. M., Abou Jamra R., Koertel N., Soyris C., Polla D. L., Safra M., Zisso A., Powell C. A., Rebelo-Guiomar P., Dinges N., Morin V., Stock M., Hussain M., Shahzad M., Riazuddin S., Ahmed Z. M., Pfundt R., Schwarz F., de Boer L., Reis A., Grozeva D., Raymond F. L., Riazuddin S., Koolen D. A., Minczuk M., Roignant J., van Bokhoven H. & Schwartz S. (2018)
  • A repressor-decay timer for robust temporal patterning in embryonic Drosophila neuroblast lineages

    Averbukh I., Lai S., Doe C. Q. & Barkai N. (2018)
  • Inferring and using protein quaternary structure information from crystallographic data

    Dey S. & Levy E. D. (2018)
  • Evolutionary trade-offs and the structure of polymorphisms

    Sheftel H., Szekely P., Mayo A., Sella G. & Alon U. (2018)
  • Dramatic action: A theater-based paradigm for analyzing human interactions

    Liron Y., Raindel N. & Alon U. (2018)
  • Pax6 regulation of Sox9 in the mouse retinal pigmented epithelium controls its timely differentiation and choroid vasculature development

    Cohen-Tayar Y., Cohen H., Mitiagin Y., Abravanel Z., Levy C., Idelson M., Reubinoff B., Itzkovitz S., Raviv S., Kaestner K. H., Blinder P., Elkon R. & Ashery-Padan R. (2018)
  • Sybil-Resilient Reality-Aware Social Choice

    Shahaf G., Shapiro E. & Talmon N. (2018)
  • Incorporating Reality into Social Choice

    Shapiro E. & Talmon N. (2018)
  • Repertoires of tRNAs: The Couplers of Genomics and Proteomics

    Rak R., Dahan O. & Pilpel Y. (2018)
  • Bile acids in glucose metabolism in health and disease

    Shapiro H., Kolodziejczyk A. A., Halstuch D. & Elinav E. (2018)
  • Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer

    Shee K., Yang W., Hinds J. W., Hampsch R. A., Varn F. S., Traphagen N. A., Patel K., Cheng C., Jenkins N. P., Kettenbach A. N., Demidenko E., Owens P., Faber A. C., Golub T. R., Straussman R. & Miller T. W. (2018)
  • Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency

    Mor N., Rais Y., Sheban D., Peles S., Aguilera-Castrejon A., Zviran A., Elinger D., Viukov S., Geula S., Krupalnik V., Zerbib M., Chomsky E., Lasman L., Shani T., Bayerl J., Gafni O., Hanna S., Buenrostro J. D., Hagai T., Masika H., Vainorius G., Bergman Y., Greenleaf W. J., Esteban M. A., Elling U., Levin Y., Massarwa R., Merbl Y., Novershtern N. & Hanna J. H. (2018)
  • Role of the gut microbiota in nutrition and health

    Valdes A. M., Walter L., Segal E. & Spector T. D. (2018)
  • Single-Cell Genomics: A Stepping Stone for Future Immunology Discoveries

    Giladi A. & Amit I. (2018)
  • Temporal Stability of the Healthy Human Skin Microbiome Following Dead Sea Climatotherapy

    Brandwein M., Fuks G., Israel A., Al-Ashhab A., Nejman D., Straussman R., Hodak E., Harari M., Steinberg D., Bentwich Z., Shental N. & Meshner S. (2018)
  • MTCH2-mediated mitochondrial fusion drives exit from naive pluripotency in embryonic stem cells

    Bahat A., Goldman A., Zaltsman Y., Khan D. H., Halperin C., Amzallag E., Krupalnik V., Mullokandov M., Silberman A., Erez A., Schimmer A. D., Hanna J. H. & Gross A. (2018)
  • NKp46 Receptor-Mediated Interferon-gamma Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis

    Glasner A., Levi A., Enk J., Isaacson B., Viukov S., Orlanski S., Scope A., Neuman T., Enk C. D., Hanna J. H., Sexl V., Jonjic S., Seliger B., Zitvogel L. & Mandelboim O. (2018)
  • The Helix Twist: Damage and Repair Follows the DNA Minor Groove

    Kotler E. & Segal E. (2018)
  • Aggregation over Metric Spaces: Proposing and Voting in Elections, Budgeting, and Legislation

    Shahaf G., Shapiro E. & Talmon N. (2018)
  • Phospho-regulation of ATOH1 Is Required for Plasticity of Secretory Progenitors and Tissue Regeneration

    Tomic G., Morrissey E., Kozar S., Ben-Moshe S., Hoyle A., Azzarelli R., Kemp R., Chilamakuri C. S. R., Itzkovitz S., Philpott A. & Winton D. J. (2018)
  • Bacterial Noncoding RNAs Excised from within Protein-Coding Transcripts

    Dar D. & Sorek R. (2018)
  • Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT

    Suez J., Zmora N., Zilberman-Schapira G., Mor U., Dori-Bachash M., Bashiardes S., Zur M., Regev-Lehavi D., Brik R. B., Federici S., Horn M., Cohen Y., Moor A. E., Zeevi D., Korem T., Kotler E., Harmelin A., Itzkovitz S., Maharshak N., Shibolet O., Pevsner-Fischer M., Shapiro H., Sharon I., Halpern Z., Segal E. & Elinav E. (2018)
  • Virus-Induced Changes in mRNA Secondary Structure Uncover cis-Regulatory Elements that Directly Control Gene Expression

    Mizrahi O., Nachshon A., Shitrit A., Gelbart I. A., Dobesova M., Brenner S., Kahana C. & Stern-Ginossar N. (2018)
  • Immune cell type 'fingerprints' at the basis of outcome diversity of human infection

    Hen-Avivi S. & Avraham R. (2018)
  • Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting

    Cohen M., Giladi A., Gorki A., Galbard Solodkin D., Zada M., Hladik A., Miklosi A., Salame T., Halpern K. B., David E., Itzkovitz S., Harkany T., Knapp S. & Amit I. (2018)
  • A model for 'sustainable' US beef production

    Eshel G., Shepon A., Shaket T., Cotler B. D., Gilutz S., Giddings D., Raymo M. E. & Milo R. (2018)
  • Production of Spliced Long Noncoding RNAs Specifies Regions with Increased Enhancer Activity

    Gil N. & Ulitsky I. (2018)
  • Robust stochastic Turing patterns in the development of a one-dimensional cyanobacterial organism

    Di Patti F., Lavacchi L., Arbel-Goren R., Schein-Lubomirsky L., Fanelli D. & Stavans J. (2018)
  • Regulation of Neuroregeneration by Long Noncoding RNAs

    Perry R. B., Hezroni H., Goldrich M. J. & Ulitsky I. (2018)
  • Cnidarian Cell Type Diversity and Regulation Revealed by Whole-Organism Single-Cell RNA-Seq

    Sebe-Pedros A., Saudemont B., Chomsky E., Plessier F., Mailhe M., Renno J., Loe-Mie Y., Lifshitz A., Mukamel Z., Schmutz S., Novault S., Steinmetz P. R. H., Spitz F., Tanay A. & Marlow H. (2018)
  • Epigenetic Control of Expression Homeostasis during Replication Is Stabilized by the Replication Checkpoint

    Voichek Y., Mittelman K., Gordon Y., Bar-Ziv R., Smit D. L., Shenhav R. & Barkai N. (2018)
  • Dissection of Influenza Infection In Vivo by Single-Cell RNA Sequencing

    Steuerman Y., Cohen M., Peshes-Yaloz N., Valadarsky L., Cohn O., David E., Frishberg A., Mayo L., Bacharach E., Amit I. & Gat-Viks I. (2018)
  • Probiotics administration following sleeve gastrectomy surgery: a randomized double-blind trial

    Sherf-Dagan S., Zelber-Sagi S., Zilberman-Schapira G., Webb M., Buch A., Keidar A., Raziel A., Sakran N., Goitein D., Goldenberg N., Mahdi J. A., Pevsner-Fischer M., Zmora N., Dori-Bachash M., Segal E., Elinav E. & Shibolet O. (2018)
  • Extensive reshaping of bacterial operons by programmed mRNA decay

    Dar D. & Sorek R. (2018)
  • Prediction of acute myeloid leukaemia risk in healthy individuals

    Abelson S., Collord G., Ng S. W. K., Weissbrod O., Mendelson Cohen N., Niemeyer E., Barda N., Zuzarte P. C., Heisler L., Sundaravadanam Y., Luben R., Hayat S., Wang T. T., Zhao Z., Cirlan I., Pugh T. J., Soave D., Ng K., Latimer C., Hardy C., Raine K., Jones D., Hoult D., Britten A., McPherson J. D., Johansson M., Mbabaali F., Eagles J., Miller J. K., Pasternack D., Timms L., Krzyzanowski P., Awadalla P., Costa R., Segal E., Bratman S. V., Beer P., Behjati S., Martincorena I., Wang J. C. Y., Bowles K. M., Quirós J. R., Karakatsani A., La Vecchia C., Trichopoulou A., Salamanca-Fernández E., Huerta J. M., Barricarte A., Travis R. C., Tumino R., Masala G., Boeing H., Panico S., Kaaks R., Krämer A., Sieri S., Riboli E., Vineis P., Foll M., McKay J., Polidoro S., Sala N., Khaw K., Vermeulen R., Campbell P. J., Papaemmanuil E., Minden M. D., Tanay A., Balicer R. D., Wareham N. J., Gerstung M., Dick J. E., Brennan P., Vassiliou G. S. & Shlush L. I. (2018)
  • The opportunity cost of animal based diets exceeds all food losses

    Shepon A., Eshel G., Noor E. & Milo R. (2018)
  • Interactions between short and long noncoding RNAs

    Ulitsky I. (2018)
  • RNA editing in bacteria: occurrence, regulation and significance

    Bar-Yaacov D., Pilpel Y. & Dahan O. (2018)
  • Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing

    Shnayder M., Nachshon A., Krishn B., Poole E., Boshkov A., Binyamin A., Maza I., Sinclair J., Schwartz M. & Stern-Ginossar N. (2018)
  • Human brain organoids on a chip reveal the physics of folding

    Karzbrun E., Kshirsagar A., Cohen S. R., Hanna J. H. & Reiner O. (2018)
  • Paired-cell sequencing enables spatial gene expression mapping of liver endothelial cells

    Halpern K. B., Shenhav R., Massalha H., Toth B., Egozi A., Massasa E. E., Medgalia C., David E., Giladi A., Moor A. E., Porat Z., Amit I. & Itzkovitz S. (2018)
  • Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner

    Thion M. S., Low D., Silvin A., Chen J., Grisel P., Schulte-Schrepping J., Blecher R., Ulas T., Squarzoni P., Hoeffel G., Coulpier F., Siopi E., David F. S., Scholz C., Shihui F., Lum J., Amoyo A. A., Larbi A., Poidinger M., Buttgereit A., Lledo P., Greter M., Chan J. K. Y., Amit I., Beyer M., Schultze J. L., Schlitzer A., Pettersson S., Ginhoux F. & Garel S. (2018)
  • Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures

    Lee J. S., Adler L., Karathia H., Carmel N., Rabinovich S., Auslander N., Keshet R., Stettner N., Silberman A., Agemy L., Helbling D., Eilam R., Sun Q., Brandis A., Malitsky S., Itkin M., Weiss H., Pinto S., Kalaora S., Levy R., Barnea E., Admon A., Dimmock D., Stern-Ginossar N., Scherz A., Nagamani S. C. S., Unda M., Wilson D. M., Elhasid R., Carracedo A., Samuels Y., Hannenhalli S., Ruppin E. & Erez A. (2018)
  • Towards utilization of the human genome and microbiome for personalized nutrition

    Bashiardes S., Godneva A., Elinav E. & Segal E. (2018)
  • Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection

    Thaiss C. A., Levy M., Grosheva I., Zheng D., Soffer E., Blacher E., Braverman S., Tengeler A. C., Barak O., Elazar M., Ben-Zeev R., Lehavi-Regev D., Katz M. N., Pevsner-Fischer M., Gertler A., Halpern Z., Harmelin A., Aamar S., Serradas P., Grosfeld A., Shapiro H., Geiger B. & Elinav E. (2018)
  • Global Cryptodemocracy Is Possible and Desirable

    Shapiro E. (2018)
  • Identification of a unique Staphylococcus aureus ribosomal signature in severe atopic dermatitis

    Brandwein M., Fuks G., Israel A., Nejman D., Straussman R., Hodak E., Harari M., Steinberg D., Bentwich Z., Shental N. & Meshner S. (2018)
  • Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

    Deczkowska A., Keren-Shaul H., Weiner A., Colonna M., Schwartz M. & Amit I. (2018)
  • Quantitative species-level ecology of reef fish larvae via metabarcoding

    Kimmerling N., Zuqert O., Amitai G., Gurevich T., Armoza-Zvuloni R., Kolesnikov I., Berenshtein I., Melamed S., Gilad S., Benjamin S., Rivlin A., Ohavia M., Paris C. B., Holzman R., Kiflawi M. & Sorek R. (2018)
  • Subepithelial telocytes are an important source of Wnts that supports intestinal crypts

    Shoshkes-Carmel M., Wang Y. J., Wangensteen K. J., Toth B., Kondo A., Massassa E. E., Itzkovitz S. & Kaestner K. H. (2018)
  • Genome-wide SWAp-Tag yeast libraries for proteome exploration

    Weill U., Yofe I., Sass E., Stynen B., Davidi D., Natarajan J., Ben-Menachem R., Avihou Z., Goldman O., Harpaz N., Chuartzman S., Kniazev K., Knoblach B., Laborenz J., Boos F., Kowarzyk J., Ben-Dor S., Zalckvar E., Herrmann J. M., Rachubinski R. A., Pines O., Rapaport D., Michnick S. W., Levy E. D. & Schuldiner M. (2018)
  • The GET pathway can increase the risk of mitochondrial outer membrane proteins to be mistargeted to the ER

    Vitali D. G., Sinzel M., Bulthuis E. P., Kolb A., Zabel S., Mehlhorn D. G., Costa B. F., Farkas A., Clancy A., Schuldiner M., Grefen C., Schwappach B., Borgese N. & Rapaport D. (2018)
  • A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation

    Kotler E., Shani O., Goldfeld G., Lotan-Pompan M., Tarcic O., Gershoni A., Hopf T. A., Marks D. S., Oren M. & Segal E. (2018)
  • Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment

    Lauridsen F. K. B., Jensen T. L., Rapin N., Aslan D., Wilhelmson A. S., Pundhir S., Rehn M., Paul F., Giladi A., Hasemann M. S., Serup P., Amit I. & Porse B. T. (2018)
  • Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells

    Bornstein C., Nevo S., Giladi A., Kadouri N., Pouzolles M., Gerbe F., David E., Machado A., Chuprin A., Toth B., Goldberg O., Itzkovitz S., Taylor N., Jay P., Zimmermann V. S., Abramson J. & Amit I. (2018)
  • m(1)A within cytoplasmic mRNAs at single nucleotide resolution: a reconciled transcriptome-wide map

    Schwartz S. (2018)
  • Fold-change Response of Photosynthesis to Step Increases of Light Level

    Tendler A., Wolf B. C., Tiwari V., Alon U. & Danon A. (2018)
  • Spatial Reconstruction of Single Enterocytes Uncovers Broad Zonation along the Intestinal Villus Axis

    Moor A. E., Harnik Y., Ben-Moshe S., Massasa E. E., Rozenberg M., Eilam R., Halpern K. B. & Itzkovitz S. (2018)
  • Viral Short ORFs and Their Possible Functions

    Finkel Y., Stern-Ginossar N. & Schwartz M. (2018)
  • Decay of the Stress-Induced Ligand MICA Is Controlled by the Expression of an Alternative 3 ' Untranslated Region

    Toledano T., Vitenshtein A., Stern-Ginossar N., Seidel E. & Mandelboim O. (2018)
  • From the Human Cell Atlas to dynamic immune maps in human disease

    Adlung L. & Amit I. (2018)
  • The bone marrow is patrolled by NK cells that are primed and expand in response to systemic viral activation

    Milo I., Blecher-Gonen R., Barnett-Itzhaki Z., Bar-Ziv R., Tal O., Gurevich I., Feferman T., Drexler I., Amit I., Bousso P. & Shakhar G. (2018)
  • Functional characterization of the p53 "mutome"

    Kotler E., Segal E. & Oren M. (2018)
  • Application of Algebraic Topology to homologous recombination of DNA

    Braslavsky I. & Stavans J. (2018)
  • The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses

    Berger C. N., Crepin V. F., Roumeliotis T. I., Wright J. C., Serafini N., Pevsner-Fischer M., Yu L., Elinav E., Di Santo J. P., Choudhary J. S. & Frankel G. (2018)
  • High-resolution RNA 3 '-ends mapping of bacterial Rho-dependent transcripts

    Dar D. & Sorek R. (2018)
  • Host genetics and microbiome associations through the lens of genome wide association studies

    Weissbrod O., Rothschild D., Barkan E. & Segal E. (2018)
  • A Bird's-Eye View of Enzyme Evolution: Chemical, Physicochemical, and Physiological Considerations

    Davidi D., Longo L. M., Jablonska J., Milo R. & Tawfik D. S. (2018)
  • Positioning Europe for the EPITRANSCRIPTOMICS challenge

    Jantsch M., Quattrone A., O'Connell M., Helm M., Frye M., Macias-Gonzales M., Ohman M., Ameres S., Willems L., Fuks F., Oulas A., Vanacova S., Nielsen H., Bousquet-Antonelli C., Motorin Y., Roignant J., Balatsos N., Dinnyes A., Baranov P., Kelly V., Lamm A., Rechavi G., Pelizzola M., Liepins J., Holodnuka Kholodnyuk I., Zammit V., Ayers D., Drablos F., Dahl J. A., Bujnicki J., Jeronimo C., Almeida R., Neagu M., Costache M., Bankovic J., Banovic B., Kyselovic J., Valor L. M., Selbert S., Pir P., Demircan T., Cowling V., Schäfer M., Rossmanith W., Lafontaine D., David A., Carre C., Lyko F., Schaffrath R. & Schwartz S. (2018)
  • Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies

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  • A General Path-Based Representation for Predicting Program Properties

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  • Single molecule approaches for studying gene regulation in metabolic tissues

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  • Translating microbiome futures

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  • Early metazoan cell type diversity and the evolution of multicellular gene regulation

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  • Mind the Organelle Gap - Peroxisome Contact Sites in Disease

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  • Genome-wide C-SWAT library for high-throughput yeast genome tagging

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  • The anti-inflammatory IFITM genes ameliorate colitis and partially protect from tumorigenesis by changing immunity and microbiota

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  • Creative exploration as a scale-invariant search on a meaning landscape

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  • A Visual Framework for Classifying Determinants of Cell Size

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  • Circuit Design Features of a Stable Two-Cell System

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  • Database for High Throughput Screening Hits (dHITS): a simple tool to retrieve gene specific phenotypes from systematic screens done in yeast

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  • Identification of seipin-linked factors that act as determinants of a lipid droplet subpopulation

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  • A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies

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  • Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis

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  • The Role of m(6)A/m-RNA Methylation in Stress Response Regulation

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  • Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features

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  • On the journey from nematode to human, scientists dive by the zebrafish cell lineage tree

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  • Combining Developmental and Perturbation-Seq Uncovers Transcriptional Modules Orchestrating Neuronal Remodeling

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  • A Bacterial Growth Law out of Steady State

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  • Modulating cell state to enhance suspension expansion of human pluripotent stem cells

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  • Codon usage of highly expressed genes affects proteome-wide translation efficiency

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  • Unraveling the determinants of microRNA mediated regulation using a massively parallel reporter assay

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  • Sieving through gut models of colonization resistance

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  • Altered p53 functionality in cancer-associated fibroblasts contributes to their cancer-supporting features

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  • Impaired immune surveillance accelerates accumulation of senescent cells and aging

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  • Dynamic proteomics reveals bimodal protein dynamics of cancer cells in response to HSP90 inhibitor

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  • Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine

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  • Post-translational modification profiling-functional proteomics for the analysis of immune regulation

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  • RNA editing in bacteria recodes multiple proteins and regulates an evolutionarily conserved toxin-antitoxin system

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  • The path towards microbiome-based metabolite treatment

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  • Coupling phenotypic persistence to DNA damage increases genetic diversity in severe stress

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  • Systematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulence

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  • Ectopic colonization of oral bacteria in the intestine drives T(H)1 cell induction and inflammation

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  • Saccharomyces cerevisiae cells lacking Pex3 contain membrane vesicles that harbor a subset of peroxisomal membrane proteins

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  • Communication between viruses guides lysis-lysogeny decisions

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  • Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation

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  • Dynamic zonation of liver polyploidy

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  • Inflammasomes and intestinal inflammation

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  • Placebo can enhance creativity

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  • Increased NK cell immunity in a transgenic mouse model of NKp46 overexpression

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  • Genomic Characterization of Murine Monocytes Reveals C/EBP beta Transcription Factor Dependence of Ly6C(-) Cells

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  • Multiscale 3D Genome Rewiring during Mouse Neural Development

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  • p53 is essential for DNA methylation homeostasis in naive embryonic stem cells, and its loss promotes clonal heterogeneity

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  • Combining Deep Sequencing, Proteomics, Phosphoproteomics, and Functional Screens To Discover Novel Regulators of Sphingolipid Homeostasis

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  • Cellular Consequences of Diminished Protein O-Mannosyltransferase Activity in Baker's Yeast

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  • Optimal Regulatory Circuit Topologies for Fold-Change Detection

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  • Buffering Global Variability of Morphogen Gradients

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  • m(6)A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover

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  • Citrobacter rodentium Subverts ATP Flux and Cholesterol Homeostasis in Intestinal Epithelial Cells In Vivo

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  • Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators

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  • Principles of Systems Biology, No. 14

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  • Cell-cycle dynamics of chromosomal organization at single-cell resolution

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  • The Genetic Requirements for Pentose Fermentation in Budding Yeast

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  • MICROBIOLOGY Intracellular signaling in CRISPR-Cas defense

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  • The human lncRNA LINC-PINT inhibits tumor cell invasion through a highly conserved sequence element

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  • Syp1 regulates the clathrin-mediated and clathrin-independent endocytosis of multiple cargo proteins through a novel sorting motif

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  • Editorial overview: Systems biology for biotechnology

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  • NFIL-trating the Host Circadian Rhythm-Microbes Fine-Tune the Epithelial Clock

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  • OCT4 impedes cell fate redirection by the melanocyte lineage master regulator MITF in mouse ESCs

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  • Principles of cellular resource allocation revealed by condition-dependent proteome profiling

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  • Principles of Systems Biology, No. 21

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  • An Endogenously Tagged Fluorescent Fusion Protein Library in Mouse Embryonic Stem Cells

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  • Targeting and translocation of proteins to the endoplasmic reticulum at a glance

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  • Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress

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  • Lessons on enzyme kinetics from quantitative proteomics

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  • Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses

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  • Coordinated Pulses of mRNA and of Protein Translation or Degradation Produce EGF-Induced Protein Bursts

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  • A pathway of targeted autophagy is induced by DNA damage in budding yeast

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  • RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure

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  • GAS6 is a key homeostatic immunological regulator of host-commensal interactions in the oral mucosa

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  • A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease

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  • Efficient and Accurate Translation Initiation Directed by TISU Involves RPS3 and RPS10e Binding and Differential Eukaryotic Initiation Factor 1A Regulation

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  • Exhaustive search of linear information encoding protein-peptide recognition

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  • Iron affects Ire1 clustering propensity and the amplitude of endoplasmic reticulum stress signaling

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  • Engineering carbon fixation in E. coil: from heterologous RuBisCO expression to the Calvin-Benson-Bassham cycle: from heterologous RuBisCO expression to the Calvin-Benson-Bassham cycle

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  • Global mRNA polarization regulates translation efficiency in the intestinal epithelium

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  • Two novel effectors of trafficking and maturation of the yeast plasma membrane H+-ATPase

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  • Sequence features of viral and human Internal Ribosome Entry Sites predictive of their activity

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  • Cap-binding protein 4EHP effects translation silencing by microRNAs

    Chapat C., Jafarnejad S. M., Matta-Camacho E., Hesketh G. G., Gelbart I. A., Attig J., Gkogkas C. G., Alain T., Stern-Ginossar N., Fabian M. R., Gingras A., Duchaine T. F. & Sonenberg N. (2017)
  • MicroRNA-142 controls thymocyte proliferation

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  • TRUB1 is the predominant pseudouridine synthase acting on mammalian mRNA via a predictable and conserved code

    Safra M., Nir R., Farouq D., Slutzkin I. V. & Schwartz S. (2017)
  • Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq

    Medaglia C., Giladi A., Stoler-Barak L., De Giovanni M., Salame T. M., Biram A., David E., Li H., Iannacone M., Shulman Z. & Amit I. (2017)
  • Analysis of blood-based gene expression in idiopathic Parkinson disease

    Shamir R., Klein C., Amar D., Vollstedt E., Bonin M., Usenovic M., Wong Y. C., Maver A., Poths S., Safer H., Corvol J., Lesage S., Lavi O., Deuschl G., Kuhlenbaeumer G., Pawlack H., Ulitsky I., Kasten M., Riess O., Brice A., Peterlin B. & Krainc D. (2017)
  • Scaling single-cell genomics from phenomenology to mechanism

    Tanay A. & Regev A. (2017)
  • Evidence for a cytoplasmic pool of ribosome-free mRNAs encoding inner membrane proteins in Escherichia coli

    Benhalevy D., Biran I., Bochkareva E. S., Sorek R. & Bibi E. (2017)
  • Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome

    Schwartzman O., Savino A. M., Gombert M., Palmi C., Cario G., Schrappe M., Eckert C., von Stackelberg A., Huang J., Hameiri-Grossman M., Avigad S., te Kronnie G., Geron I., Birger Y., Rein A., Zarfati G., Fischer U., Mukamel Z., Stanulla M., Biondi A., Cazzaniga G., Vetere A., Wagner B. K., Chen Z., Chen S., Tanay A., Borkhardt A. & Izraeli S. (2017)
  • Sub-cellular mRNA localization modulates the regulation of gene expression by small RNAs in bacteria

    Teimouri H., Korkmazhan E., Stavans J. & Levine E. (2017)
  • Science Forum: The Human Cell Atlas

    Regev A., Teichmann S. A., Lander E. S., Amt I., Benoist C., Birney E., Bodenmiller B., Campbell P., Carninci P., Clatworthy M., Clevers H., Deplancke B., Dunham I., Eberwine J., Elis R., Enard W., Farmer A., Fugger L., Gottgens B., Hacohen N., Haniffa M., Hemberg M., Kim S., Klenerman P., Kriegstein A., Lein E. D., Linnarsson S., Lundberg E., Lundeberg J., Majumder P., Marioni J. C., Merad M., Mhlanga M., Nawijin M., Netea M., Nolan G., Pe'er D., Phillipakis A., Ponting C. P., Quake S., Reik W., Rozenblatt-Rosen O., Sanes J., Satija R., Schumacher T. N., Shalek A., Shapiro E., Sharma P., Shin J. W., Stegle O. & (2017)
  • Single-cell spatial reconstruction reveals global division of labour in the mammalian liver

    Halpern K. B., Shenhav R., Matcovitch-Natan O., Toth B., Lemze D., Golan M., Massasa E. E., Baydatch S., Landen S., Moor A. E., Brandis A., Giladi A., Stokar-Avihail A., David E., Amit I. & Itzkovitz S. (2017)
  • Genome-wide identification and expression profiling of long non-coding RNAs in auditory and vestibular systems

    Ushakov K., Koffler-Brill T., Rom A., Perl K., Ulitsky I. & Avraham K. B. (2017)
  • Dynamic Proteomics of Herpes Simplex Virus Infection

    Drayman N., Karin O., Mayo A., Danon T., Shapira L., Rafael D., Zimmer A., Bren A., Kobiler O. & Alon U. (2017)
  • Post-dieting weight gain: the role of persistent microbiome changes

    Thaiss C. A., Shapiro H. & Elinav E. (2017)
  • Dysbiosis and the immune system

    Levy M., Kolodziejczyk A. A., Thaiss C. A. & Elinav E. (2017)
  • Maya Schuldiner

    Schuldiner M. (2017)
  • Lighting Up ERK Activity

    Shilo B. & Barkai N. (2017)
  • The gut microbiome and hypertension

    Pevsner-Fischer M., Blacher E., Tatirovsky E., Ben-Dov I. & Elinav E. (2017)
  • Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner

    Deczkowska A., Matcovitch-Natan O., Tsitsou-Kampeli A., Ben-Hamo S., Dvir-Szternfeld R., Spinrad A., Singer O., David E., Winter D. R., Smith L. K., Kertser A., Baruch K., Rosenzweig N., Terem A., Prinz M., Villeda S., Citri A., Amit I. & Schwartz M. (2017)
  • A reduced-dimensionality approach to uncovering dyadic modes of body motion in conversations

    Gaziv G., Noy L., Liron Y. & Alon U. (2017)
  • The genetic basis for the adaptation of E-coli to sugar synthesis from CO2

    Herz E., Antonovsky N., Bar-On Y., Davidi D., Gleizer S., Prywes N., Noda-Garcia L., Frisch K. L., Zohar Y., Wernick D. G., Savidor A., Barenholz U. & Milo R. (2017)
  • Vesicles Spread Susceptibility to Phages

    Ofir G. & Sorek R. (2017)
  • Optimality and sub-optimality in a bacterial growth law

    Towbin B. D., Korem Y., Bren A., Doron S., Sorek R. & Alon U. (2017)
  • Systematic Investigation of Transcription Factor Activity in the Context of Chromatin Using Massively Parallel Binding and Expression Assays

    Levo M., Avnit-Sagi T., Lotan-Pompan M., Kalma Y., Weinberger A., Yakhini Z. & Segal E. (2017)
  • Role of biomechanical forces in hyperfiltration-mediated glomerular injury in congenital anomalies of the kidney and urinary tract

    Srivastava T., Thiagarajan G., Alon U. S., Sharma R., El-Meanawy A., McCarthy E. T., Savin V. J. & Sharma M. (2017)
  • AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia

    Zhou F., Liu Y., Rohde C., Pauli C., Gerloff D., Koehn M., Misiak D., Baeumer N., Cui C., Goellner S., Oellerich T., Serve H., Garcia-Cuellar M., Slany R., Maciejewski J. P., Przychodzen B., Seliger B., Klein H., Bartenhagen C., Berdel W. E., Dugas M., Taketo M. M., Farouq D., Schwartz S., Regev A., Hebert J., Sauvageau G., Pabst C., Huettelmaier S. & Mueller-Tidow C. (2017)
  • Systematic Epigenomic Analysis Reveals Chromatin States Associated with Melanoma Progression

    Fiziev P., Akdemir K. C., Miller J. P., Keung E. Z., Samant N. S., Sharma S., Natale C. A., Terranova C. J., Maitituoheti M., Amin S. B., Martinez-Ledesma E., Dhamdhere M., Axelrad J. B., Shah A., Cheng C. S., Mahadeshwar H., Seth S., Barton M. C., Protopopov A., Tsai K. Y., Davies M. A., Garcia B. A., Amit I., Chin L., Ernst J. & Rai K. (2017)
  • Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain

    Varol D., Mildner A., Blank T., Shemer A., Barashi N., Yona S., David E., Boura-Halfon S., Segal-Hayoun Y., Chappell-Maor L., Keren-Shaul H., Leshkowitz D., Hornstein E., Fuhrmann M., Amit I., Maggio N., Prinz M. & Jung S. (2017)
  • Proteins evolve on the edge of supramolecular self-assembly

    Garcia-Seisdedos H., Empereur-Mot C., Elad N. & Levy E. D. (2017)
  • The remedy within: will the microbiome fulfill its therapeutic promise?

    Thaiss C. A. & Elinav E. (2017)
  • The Role of the Immune System in Metabolic Health and Disease

    Zmora N., Bashiardes S., Levy M. & Elinav E. (2017)
  • Method for Labeling Transcripts in Individual Escherichia coli Cells for Single-molecule Fluorescence In Situ Hybridization Experiments

    Arbel-Goren R., Shapira Y. & Stavans J. (2017)
  • Gene Architectures that Minimize Cost of Gene Expression

    Frumkin I., Schirman D., Rotman A., Li F., Zahavi L., Mordret E., Asraf O., Wu S., Levy S. F. & Pilpel Y. (2017)
  • Breaking the population barrier by single cell analysis: one host against one pathogen

    Mills E. & Avraham R. (2017)
  • Microbiome at the Frontier of Personalized Medicine

    Kashyap P. C., Chia N., Nelson H., Segal E. & Elinav E. (2017)
  • Energetic cost of building a virus

    Mahmoudabadi G., Milo R. & Phillips R. (2017)
  • Computational prediction of regulatory, premature transcription termination in bacteria

    Millman A., Dar D., Shamir M. & Sorek R. (2017)
  • Model-based analysis of DNA replication profiles: predicting replication fork velocity and initiation rate by profiling free-cycling cells

    Gispan A., Carmi M. & Barkai N. (2017)
  • Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation

    Lim A. I., Li Y., Lopez-Lastra S., Stadhouders R., Paul F., Casrouge A., Serafini N., Puel A., Bustamante J., Surace L., Masse-Ranson G., David E., Strick-Marchand H., Le Bourhis B. L., Cocchi R., Topazio D., Graziano P., Muscarella L. A., Rogge L., Norel X., Sallenave J., Allez M., Graf T., Hendriks R. W., Casanova J., Amit I., Yssel H. & Di Santo S. J. P. (2017)
  • APOL1-Mediated Cell Injury Involves Disruption of Conserved Trafficking Processes

    Kruzel-Davila E., Shemer R., Ofir A., Bavli-Kertselli I., Darlyuk-Saadon I., Oren-Giladi P., Wasser W. G., Magen D., Zaknoun E., Schuldiner M., Salzberg A., Kornitzer D., Marelja Z., Simons M. & Skorecki K. (2017)
  • Our Gut Microbiome: The Evolving Inner Self

    Kundu P., Blacher E., Elinav E. & Pettersson S. (2017)
  • Expression homeostasis during DNA replication

    Voichek Y., Bar-Ziv R. & Barkai N. (2017)
  • Gene architectures that minimize cost of gene expression

    Frumkin I., Schirman D., Rotman A. & Pilpel Y. (2017)
  • Cinacalcet as an alternative to phosphate therapy in X-linked hypophosphataemic rickets

    Alon U. S., Jarka D., Monachino P. J., VanSickle J. S. & Srivastava T. (2017)
  • Creative foraging: An experimental paradigm for studying exploration and discovery

    Hart Y., Mayo A. E., Mayo R., Rozenkrantz L., Tendler A., Alon U. & Noy L. (2017)
  • Next-generation sequencing technologies for detection of modified nucleotides in RNAs

    Schwartz S. & Motorin Y. (2017)
  • Spatial transcriptomics: paving the way for tissue-level systems biology

    Moor A. E. & Itzkovitz S. (2017)
  • Relevance of iPSC-derived human PGC-like cells at the surface of embryoid bodies to prechemotaxis migrating PGCs

    Mitsunaga S., Odajima J., Yawata S., Shioda K., Owa C., Isselbacher K. J., Shioda T. & Hanna J. (. (2017)
  • Biphasic response as a mechanism against mutant takeover in tissue homeostasis circuits

    Karin O. & Alon U. (2017)
  • Bread Affects Clinical Parameters and Induces Gut Microbiome-Associated Personal Glycemic Responses

    Korem T., Zeevi D., Zmora N., Weissbrod O., Bar N., Lotan-Pompan M., Avnit Sagi S. T., Kosower N., Malka G., Rein M., Suez J., Goldberg B. Z., Weinberger A., Levy A., Elinav E. & Segal E. (2017)
  • Corrigendum: TRUB1 is the predominant pseudouridine synthase acting on mammalian mRNA via a predictable and conserved code

    Safra M., Nir R., Farouq D., Vainberg Slutskin I. & Schwartz S. (2017)
  • High-Resolution Dissection of Conducive Reprogramming Trajectory to Ground State Pluripotency

    Zviran A., Mor N., Rais Y., Gingold H., Peles S., Chomsky E., Viukov S., Buenrostro J. D., Weinberger L., Manor Y. S., Krupalnik V., Zerbib M., Hezroni H., Jaitin D. A., Larastiaso D., Gilad S., Benjamin S., Mousa A., Ayyash M., Sheban D., Bayerl J., Aguilera Castrejon A., Massarwa R., Maza I., Hanna S., Amit I., Stelzer Y., Ulitsky I., Greenleaf W. J., Pilpel Y., Novershtern N. & Hanna J. H. (2017)
  • Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale

    Morgenstern M., Stiller S. B., Luebbert P., Peikert C. D., Dannenmaier S., Drepper F., Weill U., Hoess P., Feuerstein R., Gebert M., Bohnert M., van der Laan d. L. M., Schuldiner M., Schuetze C., Oeljeklaus S., Pfanner N., Wiedemann N. & Warscheid B. (2017)
  • Microbiome-Modulated Metabolites at the Interface of Host Immunity

    Blacher E., Levy M., Tatirovsky E. & Elinav E. (2017)
  • Characterization of proteome dynamics during growth in oleate reveals a new peroxisome-targeting receptor

    Yifrach E., Chuartzman S., Dahan N., Maskit S., Zada L., Weill U., Yofe I., Olender T., Schuldiner M. & Zalckvar E. (2016)
  • Microglia development follows a stepwise program to regulate brain homeostasis.

    Matcovitch-Natan O., Winter D. R., Giladi A., Vargas Aguilar A. S., Spinrad A., Sarrazin S., Ben-Yehuda H., David E., Zelada Gonzalez G. F., Perrin P., Keren-Shaul H., Gury M., Lara-Astaiso D., Thaiss C. A., Cohen M., Bahar Halpern H. K., Baruch K., Deczkowska A., Lorenzo Vivas V. E., Itzkovitz S., Elinav E., Sieweke M. H., Schwartz M. & Amit I. (2016)
  • Corrigendum: Failure to replicate the STAP cell phenomenon (vol 525, pg E6, 2015)

    De Los Angeles A., Ferrari F., Fujiwara Y., Mathieu R., Lee S., Lee S., Tu H., Ross S., Chou S., Minh Nguyen, Wu Z., Theunissen T. W., Powell B. E., Imsoonthornruksa S., Chen J., Borkent M., Krupalnik V., Lujan E., Wernig M., Hanna J. H., Hochedlinger K., Pei D., Jaenisch R., Deng H., Orkin S. H., Park P. J. & Daley G. Q. (2016)
  • Biological causal links on physiological and evolutionary time scales.

    Karmon A. & Pilpel Y. (2016)
  • The Genetic Program of Pancreatic beta-Cell Replication In Vivo

    Klochendler A., Caspi I., Corem N., Moran M., Friedlich O., Elgavish S., Nevo Y., Helman A., Glaser B., Eden A., Itzkovitz S. & Dor Y. (2016)
  • Accuracy of Answers to Cell Lineage Questions Depends on Single-Cell Genomics Data Quality and Quantity.

    Spiro A. & Shapiro E. (2016)
  • 3 ' UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells

    Hoffman Y., Bublik D. R., Ugalde A. P., Elkon R., Biniashvili T., Agami R., Oren M. & Pilpel Y. (2016)
  • Environmentally Optimal, Nutritionally Aware Beef Replacement Plant-Based Diets.

    Eshel G., Shepon A., Noor E. & Milo R. (2016)
  • CRISPR-Cas adaptation: insights into the mechanism of action.

    Amitai G. & Sorek R. (2016)
  • Talking about cross-talk: the immune system and the microbiome.

    Zeevi D., Korem T. & Segal E. (2016)
  • Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs

    Chen J., Shishkin A. A., Zhu X., Kadri S., Maza I., Guttman M., Hanna J. H., Regev A. & Garber M. (2016)
  • A Tunable Mechanism Determines the Duration of the Transgenerational Small RNA Inheritance in C. elegans

    Houri-Ze'evi L., Korem Y., Sheftel H., Faigenbloom L., Toker I. A., Dagan Y., Awad L., Degani L., Alon U. & Rechavi O. (2016)
  • Expression homeostasis during DNA replication

    Voichek Y., Bar-Ziv R. & Barkai N. (2016)
  • Mice lacking WRB reveal differential biogenesis requirements of tail-anchored proteins in vivo

    Rivera-Monroy J., Musiol L., Unthan-Fechner K., Farkas A., Clancy A., Coy-Vergara J., Weill U., Gockel S., Lin S., Corey D. P., Kohl T., Stroebel P., Schuldiner M., Schwappach B. & Vilardi F. (2016)
  • Interaction of Metabolome and Microbiome Contributes to Dietary Glycemia-induced Age-related Macular Degeneration in Aged C57BL/6J Mice

    Rowan S., Iang S., Chang M., Szymanski L., Korem T., Segal E., Cassalman C., McGuire C., Balea J. D., Clish C. B. & Taylor A. (2016)
  • Would you like to play together? Adults' attachment and the mirror game

    Feniger-Schaal R., Noy L., Hart Y., Koren-Karie N., Mayo A. E. & Alon U. (2016)
  • A systematic view on influenza induced host shutoff

    Bercovich-Kinori A., Tai J., Gelbart I. A., Shitrit A., Ben Moshe M. S., Drori Y., Itzkovitz S., Mandelboim M. & Stern-Ginossar N. (2016)
  • Metabolites: messengers between the microbiota and the immune system

    Levy M., Thaiss C. A. & Elinav E. (2016)
  • LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer.

    Sas-Chen A., Aure M. R., Leibovich L., Carvalho S., Enuka Y., Korner C., Polycarpou-Schwarz M., Lavi S., Nevo N., Kuznetsov Y., Yuan J., Azuaje F., Ulitsky I., Diederichs S., Wiemann S., Yakhini Z., Kristensen V. N., Borresen-Dale A. & Yarden Y. (2016)
  • Rapid evolutionary adaptation to growth on an 'unfamiliar' carbon source.

    Tamari Z., Yona A. H., Pilpel Y. & Barkai N. (2016)
  • > functions of long noncoding RNAs in development and stem cells

    Ulitsky I. & Perry R. (2016)
  • Regulation of membrane trafficking during glucose starvation

    Hong H., Martinez-Marquez J. Y., Gal L., Schuldiner M. & Duncan M. C. (2016)
  • A conserved abundant cytoplasmic long noncoding RNA modulates repression by Pumilio proteins in human cells.

    Tichon A., Gil N., Lubelsky Y., Havkin Solomon S. T., Lemze D., Itzkovitz S., Stern-Ginossar N. & Ulitsky I. (2016)
  • Pyruvate Formate-Lyase Enables Efficient Growth of Escherichia coli on Acetate and Formate

    Zelcbuch L., Lindner S. N., Zegman Y., Slutskin I. V., Antonovsky N., Gleizer S., Milo R. & Bar-Even A. (2016)
  • Natural Diversity in Pentose Fermentation Is Explained by Variations in Histone Deacetylases.

    Tamari Z. & Barkai N. (2016)
  • Repeat Size Determination by Two Molecular Rulers in the Type I-E CRISPR Array

    Goren M. G., Doron S., Globus R., Amitai G., Sorek R. & Qimron U. (2016)
  • SnapShot: Timescales in Cell Biology

    Shamir M., Milo R. & Bar-On Y. (2016)
  • CEACAM1-Mediated Inhibition of Virus Production

    Vitenshtein A., Weisblum Y., Hauka S., Halenius A., Oiknine-Djian E., Tsukerman P., Bauman Y., Bar-On Y., Stern-Ginossar N., Enk J., Ortenberg R., Tai J., Markel G., Blumberg R. S., Hengel H., Jonjic S., Wolf D. G., Adler H., Kammerer R. & Mandelboim O. (2016)
  • Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans.

    Sender R., Fuchs S. & Milo R. (2016)
  • Prediction of multidimensional drug dose responses based on measurements of drug pairs

    Zimmer A., Katzir I., Dekel E., Mayo A. E., Alon U., Arcavi I., Challis P., Chambers K. C., Chen T. -., Cowperthwaite P. S., Gal-Yam A., Hosseinzadeh G., Howell D. A., Inserra C., Kankare E., Magnier E. A., Maguire K., Mazzali P. A., McCully C., Milisavljevic D., Smith K. W., Taubenberger S., Valenti S., Wainscoat R. J., Yaron O. & Young D. R. (2016)
  • Microbiota Diumal Rhythmicity Programs Host Transcriptome Oscillations

    Thaiss C., Levy M., Korem T., Dohnalova L., Shapiro H., Jaitin D., David E., Winter D., Gury-BenAri M., Tatirovsky E., Tuganbaev T., Federici S., Zmora N., Zeevi D., Dori-Bachash M., Pevsner-Fischer M., Kartvelishvily E., Brandis A., Harmelin A., Shibolet O., Halpern Z., Honda K., Amit I., Segal E. & Elinav E. (2016)
  • Use of Metatranscriptomics in Microbiome Research.

    Bashiardes S., Zilberman-Schapira G. & Elinav E. (2016)
  • The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis

    Amit I., Winter D. R. & Jung S. (2016)
  • Young phosphorylation is functionally silent

    Matalon O., Dubreuil B. & Levy E. D. (2016)
  • A perspective on single cell behavior during infection

    Avraham R. & Hung D. T. (2016)
  • Dynamic stem cell states: naive to primed pluripotency in rodents and humans

    Weinberger L., Ayyash M., Novershtern N. & Hanna J. (2016)
  • Natural selection underlies apparent stress-induced mutagenesis in a bacteriophage infection model

    Yosef I., Edgar R., Levy A., Amitai G., Sorek R., Munitz A., Qimron U., Mueller B., Tarkowski P. & Weiss D. (2016)
  • Cinacalcet as adjunctive therapy in pseudohypoparathyroidism type 1b

    Srivastava T., Krudys J., Mardis N. J., Sebestyen-VanSickle J. & Alon U. S. (2016)
  • Regioselectivity of third-row maingroup dicarbides, C2X (X = K-Br) for CO interaction: Fukui function and topological analyses

    Parida S. K., Sahu S., Sharma S., Mao R., Pevsner-Fischer M., Ben-horin S., Elinav E., Zeng Z., Chen B., He Y., Xiang A. P. & Chen M. (2016)
  • eSTGt: a programming and simulation environment for population dynamics

    Spiro A. & Shapiro E. (2016)
  • Non-alcoholic fatty liver and the gut microbiota.

    Bashiardes S., Shapiro H., Rozin S., Shibolet O. & Elinav E. (2016)
  • Persistent microbiome alterations modulate the rate of post-dieting weight regain

    Thaiss C. A., Itav S., Rothschild D., Meijer M. T., Levy M., Moresi C., Dohnalová L., Braverman S., Rozin S., Malitsky S., Dori-Bachash M., Kuperman Y., Biton I., Gertler A., Harmelin A., Shapiro H., Halpern Z., Aharoni A., Segal E. & Elinav E. (2016)
  • PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease

    Baruch K., Deczkowska A., Rosenzweig N., Tsitsou-Kampeli A., Sharif A. M., Matcovitch-Natan O., Kertser A., David E., Amit I. & Schwartz M. (2016)
  • Evolution to the rescue: using comparative genomics to understand long non-coding RNAs

    Ulitsky I. (2016)
  • Mitochondrial 16S rRNA Is Methylated by tRNA Methyltransferase TRMT61B in All Vertebrates

    Bar Yaacov Y. D., Frumkin I., Yashiro Y., Chujo T., Ishigami Y., Chemla Y., Blumberg A., Schlesinger O., Bieri P., Greber B., Ban N., Zarivach R., Alfonta L., Pilpel Y., Suzuki T. & Mishmar D. (2016)
  • Pax6 role in the regulation of retinal pigmented epithelium maturation

    Cohen Y., Blinder P., Idelson M., Reubinoff B., Itzkovitz S. & Ashery-Padan R. (2016)
  • Manipulating the Placebo Response in Experimental Pain by Altering Doctor's Performance Style

    Czerniak E., Biegon A., Ziv A., Karnieli-Miller O., Weiser M., Alon U. & Citron A. (2016)
  • The mutation spectrum in genomic late replication domains shapes mammalian GC content

    Kenigsberg E., Yehuda Y., Marjavaara L., Keszthelyi A., Chabes A., Tanay A. & Simon I. (2016)
  • Exit from Synchrony in Joint Improvised Motion

    Dahan A., Noy L., Hart Y., Mayo A. & Alon U. (2016)
  • Making Sense of the Yeast Sphingolipid Pathway

    Megyeri M., Riezman H., Schuldiner M. & Futerman A. H. (2016)
  • Water-Transfer Slows Aging in Saccharomyces cerevisiae

    Cohen A., Weindling E., Rabinovich E., Nachman I., Fuchs S., Chuartzman S., Gal L., Schuldiner M. & Bar-Nun S. (2016)
  • Energy and protein feed-to-food conversion efficiencies in the US and potential food security gains from dietary changes

    Shepon A., Eshel G., Noor E. & Milo R. (2016)
  • Tumor suppressor crosstalk: Modulation of p53 activity by the Hippo pathway

    Oren M., Furth N., Ben-Moshe N. B., Porat Z., Domany E., Pozniak Y., Geiger T. & Aylon Y. (2016)
  • Combgap Promotes Ovarian Niche Development and Chromatin Association of EcR-BindingRegions in BR-C

    Hitrik A., Popliker M., Gancz D., Mukamel Z., Lifshitz A., Schwartzman O., Tanay A. & Gilboa L. (2016)
  • Parkinson disease (PARK) genes are somatically mutated in cutaneous melanoma.

    Inzelberg R., Samuels Y., Azizi E., Qutob N., Inzelberg L., Domany E., Schechtman E. & Friedman E. (2016)
  • A highly multiplexed and sensitive RNA-seq protocol for simultaneous analysis of host and pathogen transcriptomes.

    Avraham R., Haseley N., Fan A., Bloom-Ackermann Z., Livny J. & Hung D. T. (2016)
  • The multicellular nature of filamentous heterocyst-forming cyanobacteria

    Stavans J., Flores E. & Herrero A. (2016)
  • A Tether is a Tether is a Tether: Tethering at Membrane Contact Sites

    Eisenberg-Bord M., Shai N., Schuldiner M. & Bohnert M. (2016)
  • Distinct biological events generated by ECM proteolysis by two homologous collagenases

    Solomonov I., Zehorai E., Talmi-Frank D., Wolf S. G., Shainskaya A., Zhuravlev A., Kartvelishvily E., Visse R., Levin Y., Kampf N., Jaitin D. A., David E., Amit I., Nagase H. & Sagi I. (2016)
  • Taking it Personally: Personalized Utilization of the Human Microbiome in Health and Disease.

    Zmora N., Zeevi D., Korem T., Segal E. & Elinav E. (2016)
  • Transcriptome dynamics of a broad host-range cyanophage and its hosts

    Doron S., Fedida A., Hernandez-Prieto M. A., Sabehi G., Karunker I., Stazic D., Feingersch R., Steglich C., Futschik M., Lindell D. & Sorek R. (2016)
  • Post-translational modification profiling - A novel tool for mapping the protein modification landscape in cancer

    Eisenberg-Lerner A., Ciechanover A. & Merbl Y. (2016)
  • Extracellular Matrix Proteolysis by MT1-MMP Contributes to InfluenzaInfluenza-Related Tissue Damage and Mortality

    Talmi-Frank D., Altboum Z., Solomonov I., Ziv T., Amit I. & Sagi I. (2016)
  • A role for Rtt109 in buffering gene-dosage imbalance during DNA replication

    Voichek Y., Bar-Ziv R. & Barkai N. (2016)
  • Capturing pairwise and multi-way chromosomal conformations using chromosomal walks

    Olivares-Chauvet P. H., Mukamel Z., Lifshitz A., Schwartzman O., Elkayam N., Lubling Y., Deikus G., Sebra R. & Tanay A. (2016)
  • Voices Of Biotech

    Amit I., Baker D., Barker R., Berger B., Bertozzi C., Bhatia S., Biffi A., Demichelis F., Doudna J., Dowdy S. F., Endy D., Helmstaedter M., Junca H., June C., Kamb S., Khvorova A., Kim D., Kim J., Krishnan Y., Lakadamyali M., Lappalainen T., Lewin S., Liao J., Loman N., Lundberg E., Lynd L., Martin C., Mellman I., Miyawaki A., Mummery C., Nelson K., Paz J., Peralta-Yahya P., Picotti P., Polyak K., Prather K., Qin J., Quake S., Regev A., Rogers J. A., Shetty R., Sommer M., Stevens M., Stolovitzky G., Takahashi M., Tang F., Teichmann S., Torres-Padilla M., Tripathi L., Vemula P., Verdine G., Vollmer F., Wang J., Ying J. Y., Zhang F. & Zhang T. (2016)
  • A two-step patterning process increases the robustness of periodic patterning in the fly eye

    Gavish A. & Barkai N. (2016)
  • The microbiome and innate immunity

    Thaiss C. A., Zmora N., Levy M. & Elinav E. (2016)
  • A Unique Assemblage of Engraved Plaquettes from Ein Qashish South, Jezreel Valley, Israel: Figurative and Non-Figurative Symbols of Late Pleistocene Hunters-Gatherers in the Levant

    Yaroshevich A., Bar-Yosef O., Boaretto E., Caracuta V., Greenbaum N., Porat N., Roskin J. & Alon U. (2016)
  • The Protein Cost of Metabolic Fluxes: Prediction from Enzymatic Rate Laws and Cost Minimization

    Noor E., Flamholz A., Bar-Even A., Davidi D., Milo R. & Liebermeister W. (2016)
  • M-sec regulates polarized secretion of inflammatory endothelial chemokines and facilitates CCL2-mediated lymphocyte transendothelial migration

    Barzilai S., Blecher-Gonen R., Barnett Itzhaki Z., Zauberman A., Lebel-Haziv Y., Amit I. & Alon R. (2016)
  • One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy.

    Yofe I., Weill U., Meurer M., Chuartzman S., Zalckvar E., Goldman O., Ben-Dor S., Schutze C., Wiedemann N., Knop M., Khmelinskii A. & Schuldiner M. (2016)
  • Dynamical compensation in physiological circuits

    Karin O., Swisa A., Glaser B., Dor Y. & Alon U. (2016)
  • Integration of Innate Immune Signaling.

    Thaiss C. A., Levy M., Itav S. & Elinav E. (2016)
  • The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome.

    Gury-BenAri M., Thaiss C. A., Serafini N., Winter D. R., Giladi A., Lara Astiaso A. D., Levy M., Salame T. M., Weiner A., David E., Shapiro H., Dori-Bachash M., Pevsner-Fischer M., Lorenzo Vivas V. E., Keren-Shaul H., Paul F., Harmelin A., Eberl G., Itzkovitz S., Tanay A., Di Santo S. J. P., Elinav E. & Amit I. (2016)
  • Widespread formation of alternative 3 ' UTR isoforms via transcription termination in archaea

    Dar D., Prasse D., Schmitz R. A. & Sorek R. (2016)
  • The Protease Ste24 Clears Clogged Translocons.

    Ast T., Michaelis S. & Schuldiner M. (2016)
  • Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq

    Jaitin D. A., Weiner A., Yofe I., Lara Astiaso D., Keren-Shaul H., David E., Salame T. M., Tanay A., van Oudenaarden A. & Amit I. (2016)
  • Nanoscale Engineering of Designer Cellulosomes

    Gunnoo M., Cazade P., Galera-Prat A., Nash M. A., Czjzek M., Cieplak M., Alvarez B., Morzaev D., Kahana-Edwin S., Yosepovich A., Gal-Yam E. N., Berger R., Barshack I., Domany E. & Kaufman B. (2016)
  • A network-based analysis of colon cancer splicing changes reveals a tumorigenesis-favoring regulatory pathway emanating from ELK1

    Hollander D., Donyo M., Atias N., Mekahel K., Melamed Z., Yannai S., Lev-Maor G., Shilo A., Schwartz S., Barshack I., Sharan R. & Ast G. (2016)
  • Periodic Patterning Of The Drosophila Eye Is Stabilized By The Diffusible Activator Scabrous

    Gavish A., Shwartz A., Weizman A., Schejter E., Shilo B. & Barkai N. (2016)
  • Transcript degradation and noise of small RNA-controlled genes in a switch activated network in Escherichia coli.

    Arbel-Goren R., Tal A., Parasar B., Dym A., Costantino N., Munoz-Garcia J., Court D. L. & Stavans J. (2016)
  • Global characterization of in vivo enzyme catalytic rates and their correspondence to in vitro kcat measurements

    Davidi D., Barenholz U., Goldenfeld M. & Milo R. (2016)
  • A WntD-Dependent Integral Feedback Loop Attenuates Variability in Drosophila Toll Signaling

    Rahimi N., Averbukh I., Haskel Ittah I. M., Degani N., Schejter E., Barkai N. & Shilo B. (2016)
  • An unrecognized function for COPII components in recruiting the viral replication protein BMV 1a to the perinuclear ER

    Li J., Fuchs S., Zhang J., Wellford S., Schuldiner M. & Wang X. (2016)
  • Bursting Through The Cell Cycle

    Ben Moshe M. S. & Itzkovitz S. (2016)
  • The SND proteins constitute an alternative targeting route to the endoplasmic reticulum

    Aviram N., Ast T., Costa E. A., Arakel E. C., Chuartzman S. G., Jan C. H., Hassenteufel S., Dudek J., Jung M., Schorr S., Zimmermann R., Schwappach B., Weissman J. S. & Schuldiner M. (2016)
  • Co-ChIP enables genome-wide mapping of histone mark co-occurrence at single-molecule resolution.

    Weiner A., Lara Astiaso A. D., Krupalnik V., Gafni O., David E., Winter D. R., Hanna J. H. & Amit I. (2016)
  • Protein-fragment complementation assays for large-scale analysis, functional dissection, and spatiotemporal dynamic studies of protein-protein interactions in living cells

    Michnick S. W., Landry C. R., Levy E. D., Diss G., Ear P. H., Kowarzyk J., Malleshaiah M. K., Messier V. & Tchekanda E. (2016)
  • A Minimalistic Resource Allocation Model to Explain Ubiquitous Increase in Protein Expression with Growth Rate

    Barenholz U., Keren L., Segal E. & Milo R. (2016)
  • Massively Parallel Interrogation of the Effects of Gene Expression Levels on Fitness.

    Keren L., Hausser J., Lotan-Pompan M., Vainberg Slutskin S. I., Alisar H., Kaminski S., Weinberger A., Alon U., Milo R. & Segal E. (2016)
  • Glucose becomes one of the worst carbon sources for E-coli on poor nitrogen sources due to suboptimal levels of cAMP

    Bren A., Park J. O., Towbin B. D., Dekel E., Rabinowitz J. D. & Alon U. (2016)
  • Chromatin dynamics during DNA replication.

    Bar-Ziv R., Voichek Y. & Barkai N. (2016)
  • The Cost of Protein Production.

    Kafri M., Metzl-Raz E., Jona G. & Barkai N. (2016)
  • Automated Video Analysis of Non-verbal Communication in a Medical Setting

    Hart Y., Czerniak E., Karnieli-Miller O., Mayo A. E., Ziv A., Biegon A., Citron A. & Alon U. (2016)
  • Role of the microbiome in non-gastrointestinal cancers.

    Pevsner-Fischer M., Tuganbaev T., Meijer M., Zhang S., Zeng Z., Chen M. & Elinav E. (2016)
  • A generic, cost-effective, and scalable cell lineage analysis platform

    Biezuner T., Spiro A., Raz O., Amir S., Milo L., Adar R., Chapal Ilani I. N., Berman V., Fried Y., Ainbinder E., Cohen G., Barr H. M., Halaban R. & Shapiro E. (2016)
  • Circular RNAs are long-lived and display only minimal early alterations in response to a growth factor

    Enuka Y., Lauriola M., Sas-Chen A., Ulitsky I. & Yarden Y. (2016)
  • Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing

    Decque A., Joffre O., Magalhaes J. G., Cossec J., Blecher-Gonen R., Lapaquette P., Silvin' A., Mane N., Joubert P. -., Seeler J., Albert M. L., Amit I., Amigorena S. & Dejean A. (2016)
  • Cracking the epitranscriptome.

    Schwartz S. (2016)
  • No peroxisome is an island - Peroxisome contact sites.

    Shai N., Schuldiner M. & Zalckvar E. (2016)
  • CRISPR-Cas: Spacer Diversity Determines the Efficiency of Defense

    Lopatina A. & Sorek R. (2016)
  • Evolution of domain-peptide interactions to coadapt specificity and affinity to functional diversity

    Kelil A., Levy E. D. & Michnick S. W. (2016)
  • Single molecule approaches for quantifying transcription and degradation rates in intact mammalian tissues.

    Bahar Halpern H. K. & Itzkovitz S. (2016)
  • An essential role for UTX in resolution and activation of bivalent promoters

    Dhar S. S., Lee S., Chen K., Zhu G., Oh W., Allton K., Gafni O., Kim Y. Z., Tomoiga A. S., Barton M. C., Hanna J. H., Wang Z., Li W. & Lee M. G. (2016)
  • Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria

    Dar D., Shamir M., Mellin J. R., Koutero M., Stern-Ginossar N., Cossart P. & Sorek R. (2016)
  • Dealing with Gene-Dosage Imbalance during S Phase

    Bar-Ziv R., Voichek Y. & Barkai N. (2016)
  • Methods for distinguishing between protein-coding and long noncoding RNAs and the elusive biological purpose of translation of long noncoding RNAs

    Housman G. & Ulitsky I. (2016)
  • pH determines the energetic efficiency of the cyanobacterial CO2 concentrating mechanism

    Mangan N. M., Flamholz A., Hood R. D., Milo R. & Savage D. F. (2016)
  • The dihydrofolate reductase protein-fragment complementation assay: A survival-selection assay for large-scale analysis of protein-protein interactions

    Michnick S. W., Levy E. D., Landry C. R., Kowarzyk J. & Messier V. (2016)
  • Sugar Synthesis from CO2 in Escherichia coli

    Antonovsky N., Gleizer S., Noor E., Zohar Y., Herz E., Barenholz U., Zelcbuch L., Amram S., Wides A., Tepper N., Davidi D., Bar-On Y., Bareia T., Wernick D. G., Shani I., Malitsky S., Jona G., Bar-Even A. & Milo R. (2016)
  • Revised Estimates for the Number of Human and Bacteria Cells in the Body.

    Sender R., Fuchs S. & Milo R. (2016)
  • Systematic discovery of cap-independent translation sequences in human and viral genomes

    Weingarten-Gabbay S., Elias-Kirma S., Nir R., Gritsenko A. A., Stern-Ginossar N., Yakhini Z., Weinberger A. & Segal E. (2016)
  • Synthesis And Cell-Free Cloning Of Dna Libraries Using Programmable Microfluidics

    Ben-Yehezkel T., Rival A., Raz O., Cohen R., Marx Z., Camara M., Dubern J., Koch B., Heeb S., Krasnogor N., Delattre C. & Shapiro E. (2016)
  • Cell scientist to watch - Maya Schuldiner

    Bobrowska A. & Schuldiner M. (2015)
  • A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation

    Fields A. P., Rodriguez E. H., Jovanovic M., Stern-Ginossar N., Haas B. J., Mertins P., Raychowdhury R., Hacohen N., Carr S. A., Ingolia N. T., Regev A. & Weissman J. S. (2015)
  • Nuclear Retention of mRNA in Mammalian Tissues

    Halpern K. B., Caspi I., Lemze D., Levy M., Landen S., Elinav E., Ulitsky I. & Itzkovitz S. (2015)
  • Decoding a neural circuit controlling global animal state in C-elegans

    Laurent P., Soltesz Z., Nelson G., Chen C., Arellano-Carbajal F., Levy E. & de Bono M. (2015)
  • Reactivation of epigenetically silenced miR-512 and miR-373 sensitizes lung cancer cells to cisplatin and restricts tumor growth

    Harel S., Ben-Moshe N., Aylon Y., Bublik D., Moskovits N., Toperoff G., Azaiza D., Biagoni F., Fuchs G., Wilder S., Hellman A., Blandino G., Domany E. & Oren M. (2015)
  • Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

    Paul F., Arkin Y., Giladi A., Jaitin D. A., Kenigsberg E., Keren-Shaul H., Winter D., Lara-Astiaso D., Gury M., Weiner A., David E., Cohen N., Lauridsen F. K. B., Haas S., Schlitzer A., Mildner A., Ginhoux F., Jung S., Trumpp A., Porse B. T., Tanay A. & Amit I. (2015)
  • Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples

    Korem T., Zeevi D., Suez J., Weinberger A., Avnit Sagi S. T., Pompan-Lotan M., Matot E., Jona G., Harmelin A., Cohen N., Sirota-Madi A., Thaiss C. A., Pevsner-Fischer M., Sorek R., Xavier R. J., Elinav E. & Segal E. (2015)
  • DNA Crossover Motifs Associated with Epigenetic Modifications Delineate Open Chromatin Regions in Arabidopsis.

    Shilo S., Melamed-Bessudo C., Dorone Y., Barkai N. & Levy A. (2015)
  • Peroxisystem: Harnessing systems cell biology to study peroxisomes

    Schuldiner M. & Zalckvar E. (2015)
  • Diurnal suppression of EGFR signaling by glucocorticoids: implications for tumor progression and treatment

    Lauriola M., Enuka Y., Zeisel A., D'Uva G. M., Roth L., Carvalho S., Solmi R., Domany E. & Yarden Y. (2015)
  • Lipid Droplets Are Essential for Efficient Clearance of Cytosolic Inclusion Bodies

    Moldavski O., Amen T., Levin-Zaidman S., Eisenstein M., Rogachev I., Brandis A., Kaganovich D. & Schuldiner M. (2015)
  • Quantitative visualization of alternative exon expression from RNA-seq data

    Katz Y., Wang E. T., Silterra J., Schwartz S., Wong B., Thorvaldsdottir H., Robinson J. T., Mesirov J. P., Airoldi E. M. & Burge C. B. (2015)
  • Reply to Tichenor: Proposed update to beef greenhouse gas footprint is numerically questionable and well within current uncertainty bounds

    Eshel G., Shepon A., Makov T. & Milo R. (2015)
  • One library to make them all: Streamlining yeast library creation by a SWAp-Tag (SWAT) strategy

    Weill U., Yofe I., Chuartzman S. & Schuldiner M. (2015)
  • Taming the inflammasome

    Levy M., Thaiss C. A. & Elinav E. (2015)
  • Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling.

    Levy M., Thaiss C. A., Zeevi D., Dohnalova L., Zilberman-Schapira G., Mahdi J. A., David E., Savidor A., Korem T., Herzig Y., Pevsner-Fischer M., Shapiro H., Christ A., Harmelin A., Halpern Z., Latz E., Flavell R. A., Amit I., Segal E. & Elinav E. (2015)
  • SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate

    Irie N., Weinberger L., Tang W. W. C., Kobayashi T., Viukov S., Manor Y. S., Dietmann S., Hanna J. H. & Surani M. A. (2015)
  • Third Report on Chicken Genes and Chromosomes 2015

    Schmid M., Smith J., Burt D. W., Aken B. L., Antin P. B., Archibald A. L., Ashwell C., Blackshear P. J., Boschiero C., Brown C. T., Burgess S. C., Cheng H. H., Chow W., Coble D. J., Cooksey A., Crooijmans R. P. M. A., Damas J., Davis R. V. N., de Koning K. D., Delany M. E., Derrien T., Desta T. T., Dunn I. C., Dunn M., Ellegren H., Eoery L., Erb I., Farre M., Fasold M., Fleming D., Flicek P., Fowler K. E., Fresard L., Froman D. P., Garceau V., Gardner P. P., Gheyas A. A., Griffin D. K., Groenen M. A. M., Haaf T., Hanotte O., Hart A., Haesler J., Hedges S. B., Hertel J., Howe K., Hubbard A., Hume D. A., Kaiser P., Kedra D., Kemp S. J., Klopp C., Kniel K. E., Kuo R., Lagarrigue S., Lamont S. J., Larkin D. M., Lawal R. A., Markland S. M., McCarthy F., McCormack H. A., McPherson M. C., Motegi A., Muljo S. A., Muensterberg A., Nag R., Nanda I., Neuberger M., Nitsche A., Notredame C., Noyes H., O'Connor R., O'Hare E. A., Oler A. J., Ommeh S. C., Pais H., Persia M., Pitel F., Preeyanon L., Barja P. P., Pritchett E. M., Rhoads D. D., Robinson C. M., Romanov M. N., Rothschild M., Roux P., Schmidt C. J., Schneider A., Schwartz M. G., Searle S. M., Skinner M. A., Smith C. A., Stadler P. F., Steeves T. E., Steinlein C., Sun L., Takata M., Ulitsky I., Wang Q., Wang Y., Warren W. C., Wood J. M. D., Wragg D. & Zhou H. (2015)
  • Making the case for chromatin profiling: a new tool to investigate the immune-regulatory landscape

    Winter D. R., Jung S. & Amit I. (2015)
  • Noise in gene expression is coupled to growth rate.

    Keren L., Van Dijk D. D., Weingarten-Gabbay S., Davidi D., Jona G., Weinberger A., Milo R. & Segal E. (2015)
  • Derivation of novel human ground state naive pluripotent stem cells (vol 504, pg 282, 2013)

    Gafni O., Weinberger L., Mansour A. A., Manor Y. S., Chomsky E., Ben-Yosef D., Kalma Y., Viukov S., Maza I., Zviran A., Rais Y., Shipony Z., Mukamel Z., Krupalnik V., Zerbib M., Geula S., Caspi I., Schneir D., Shwartz T., Gilad S., Amann-Zalcenstein D., Benjamin S., Amit I., Tanay A., Massarwa R., Novershtern N. & Hanna J. H. (2015)
  • High-Resolution Chromatin Dynamics during a Yeast Stress Response

    Weiner A., Hsieh T. S., Appleboim A., Chen H. V., Rahat A., Amit I., Rando O. J. & Friedman N. (2015)
  • DCs are ready to commit

    Winter D. & Amit I. (2015)
  • Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis

    Rabinovich S., Adler L., Yizhak K., Sarver A., Silberman A., Agron S., Stettner N., Sun Q., Brandis A., Helbling D., Korman S., Itzkovitz S., Dimmock D., Ulitsky I., Nagamani S. C. S., Ruppin E. & Erez A. (2015)
  • MicroRNAs silence the noisy genome

    Hoffman Y. & Pilpel Y. (2015)
  • Partitioning United States' feed consumption among livestock categories for improved environmental cost assessments

    Eshel G., Shepon A., Makov T. & Milo R. (2015)
  • Integration of gene expression and GWAS results supports involvement of calcium signaling in Schizophrenia

    Hertzberg L., Katsel P., Roussos P., Haroutunian V. & Domany E. (2015)
  • Tumor evolution inferred by patterns of miRNA expression through the course of disease, therapy and recurrence in breast cancer

    Dadiani M., Bossel N., Paluch-Shimon S., Peri G., Pavlovski A., Kahana-Edwin S., Balint N., Yosepovich A., Zundelevich A., Gal-Yam E., Berger R., Barshack I., Domany E. & Kaufman B. (2015)
  • Lymphatic vessels arise from specialized angioblasts within a venous niche

    Nicenboim J., Malkinson G., Lupo T., Asaf L., Sela Y., Mayseless O., Gibbs-Bar L., Senderovich N., Hashimshony T., Shin M. S., Jerafi-Vider A., Avraham-Davidi I., Krupalnik V., Hofi R., Almog G., Astin J. W., Golani O., Ben-Dor S., Crosier P. S., Herzog W., Lawson N. D., Hanna J. H., Yanai I. & Yaniv K. (2015)
  • A cellular and regulatory map of the cholinergic nervous system of C. elegans

    Pereira L., Kratsios P. P., Serrano-Saiz E., Sheftel H., Mayo A. E., Hall D. H., White J. G., LeBoeuf B., Garcia L. R., Alon U. & Hobert O. (2015)
  • Chronobiomics: The Biological Clock as a New Principle in Host-Microbial Interactions.

    Thaiss C. A., Levy M. & Elinav E. (2015)
  • Spatial Fluctuations in Expression of the Heterocyst Differentiation Regulatory Gene hetR in Anabaena Filaments

    Corrales-Guerrero L., Tal A., Arbel-Goren R., Mariscal V., Flores E., Herrero A. & Stavans J. (2015)
  • The Moderately Efficient Enzyme: Futile Encounters and Enzyme Floppiness

    Bar-Even A., Milo R., Noor E. & Tawfik D. (2015)
  • Evolutionary tradeoffs, Pareto optimality and the morphology of ammonite shells

    Tendler A., Mayo A. & Alon U. (2015)
  • Personalized Nutrition by Prediction of Glycemic Responses.

    Zeevi D., Korem T., Zmora N., Israeli D., Rothschild D., Weinberger A., Ben-Yacov O., Lador D., Avnit Sagi S. T., Lotan-Pompan M., Suez J., Mahdi J. A., Matot E., Malka G., Kosower N., Rein M., Zilberman-Schapira G., Dohnalova L., Pevsner-Fischer M., Bikovsky R., Halpern Z., Elinav E. & Segal E. (2015)
  • m(6)A mRNA methylation facilitates resolution of naive pluripotency toward differentiation

    Geula S., Moshitch-Moshkovitz S., Dominissini D., Mansour A. A., Kol N., Salmon-Divon M., Hershkovitz V., Peer E., Mor N., Manor Y. S., Ben-Haim M., Eyal E., Yunger S., Pinto Y., Jaitin D. A., Viukov S., Rais Y., Krupalnik V., Chomsky E., Zerbib M., Maza I., Rechavi Y., Massarwa R., Hanna S., Amit I., Levanon E. Y., Amariglio N., Stern-Ginossar N., Novershtern N., Rechavi G. & Hanna J. H. (2015)
  • Each cell counts: Hematopoiesis and immunity research in the era of single cell genomics

    Jaitin D. A., Keren-Shaul H., Elefant N. & Amit I. (2015)
  • Starvation-Dependent Regulation of Golgi Quality Control Links the TOR Signaling and Vacuolar Protein Sorting Pathways

    Dobzinski N., Chuartzman S. G., Kama R., Schuldiner M. & Gerst J. (2015)
  • NF-kappa B Regulation by NLRs: T Cells Join the Club

    Thaiss C. A. & Elinav E. (2015)
  • Rationally designed, heterologous S. cerevisiae transcripts expose novel expression determinants

    Ben-Yehezkel T., Atar S., Zur H., Diament A., Goz E., Marx T., Cohen R., Dana A., Feldman A., Shapiro E. & Tuller T. (2015)
  • Lam6 Regulates the Extent of Contacts between Organelles

    Elbaz-Alon Y., Eisenberg-Bord M., Shinder V., Stiller S., Shimoni E., Wiedemann N., Geiger T. & Schuldiner M. (2015)
  • The J protein Djp1 is involved in the targeting of mitochondrial precursor proteins

    Hansen K. G., Aviram N., Schuldiner M. & Herrmann J. M. (2015)
  • Immunogenetics. Dynamic profiling of the protein life cycle in response to pathogens

    Jovanovic M., Rooney M. S., Mertins P., Przybylski D., Chevrier N., Satija R., Rodriguez E. H., Fields A. P., Schwartz S., Raychowdhury R., Mumbach M. R., Eisenhaure T., Rabani M., Gennert D., Lu D., Delorey T., Weissman J. S., Carr S. A., Hacohen N. & Regev A. (2015)
  • Decoding Viral Infection by Ribosome Profiling

    Stern-Ginossar N. (2015)
  • Systematic Dissection of the Sequence Determinants of Gene 3 ' End Mediated Expression Control

    Shalem O., Sharon E., Lubliner S., Regev I., Lotan-Pompan M., Yakhini Z. & Segal E. (2015)
  • BREX is a novel phage resistance system widespread in microbial genomes

    Goldfarb T., Sberro H., Weinstock E., Cohen O., Doron S., Charpak-Amikam Y., Afik S., Ofir G. & Sorek R. (2015)
  • From mass cytometry to cancer prognosis

    Winter D. R., Ledergor G. & Amit I. (2015)
  • Failure to replicate the STAP cell phenomenon

    De Los Angeles L. A. A., Ferrari F., Fujiwara Y., Mathieu R., Lee S., Lee S., Tu H., Ross S., Chou S., Nguyen M., Wu Z., Theunissen T. W., Powell B. E., Imsoonthornruksa S., Chen J., Borkent M., Krupalnik V., Lujan E., Wernig M., Hanna J. H., Hochedlinger K., Pei D., Jaenisch R., Deng H., Orkin S. H., Park P. J. & Daley G. Q. (2015)
  • Down-regulation of LATS kinases alters p53 to promote cell migration.

    Furth N., Bossel Ben-Moshe B. N., Pozniak Y., Porat Z., Geiger T., Domany E., Aylon Y. & Oren M. (2015)
  • Comparative Hi-C Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture

    Rudan M. V., Barrington C., Henderson S., Ernst C., Odom D. T., Tanay A. & Hadjur S. (2015)
  • A Relay Race on the Evolutionary Adaptation Spectrum

    Yona A. H., Frumkin I. & Pilpel Y. (2015)
  • Ribosome Profiling As A Tool To Decipher Viral Complexity

    Stern-Ginossar N. & Ingolia N. T. (2015)
  • Inflammasomes and the microbiota-partners in the preservation of mucosal homeostasis

    Levy M., Thaiss C. A., Katz M. N., Suez J. & Elinav E. (2015)
  • Transcription factor binding dynamics during human ES cell differentiation

    Tsankov A. M., Gu H., Akopian V., Ziller M. J., Donaghey J., Amit I., Gnirke A. & Meissner A. (2015)
  • Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors

    Maza I., Caspi I., Zviran A., Chomsky E., Rais Y., Viukov S., Geula S., Buenrostro J., Weinberger L., Krupalnik V., Hanna S., Zerbib M., Dutton J., Greenleaf W., Massarwa R., Novershtern N. & Hanna J. (2015)
  • GenoExp: a web tool for predicting gene expression levels from single nucleotide polymorphisms

    Manor O. & Segal E. (2015)
  • Distinct Murine Mucosal Langerhans Cell Subsets Develop from Pre-dendritic Cells and Monocytes

    Capucha T., Mizraji G., Segev H., Blecher-Gonen R., Winter D., Khalaileh A., Tabib Y., Attal T., Nassar M., Zelentsova K., Kisos H., Zenke M., Sere K., Hieronymus T., Burstyn-Cohen T., Amit I., Wilensky A. & Hovav A. (2015)
  • Inferring biological tasks using Pareto analysis of high-dimensional data

    Hart Y., Sheftel H., Hausser J., Szekely P., Ben-Moshe N. B., Korem Y., Tendler A., Mayo A. E. & Alon U. (2015)
  • The Transcription and Translation Landscapes during Human Cytomegalovirus Infection Reveal Novel Host-Pathogen Interactions.

    Tirosh O., Cohen Y., Shitrit A., Shani O., Le-Trilling V. T. K., Trilling M., Friedlander G., Tanenbaum M. & Stern-Ginossar N. (2015)
  • Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses

    Avraham R., Haseley N., Brown D., Penaranda C., Jijon H. B., Trombetta J. J., Satija R., Shalek A. K., Xavier R. J., Regev A. & Hung D. T. (2015)
  • Deterministic direct reprogramming of somatic cells to pluripotency (vol 502, pg 65, 2013)

    Rais Y., Zviran A., Geula S., Gafni O., Chomsky E., Viukov S., Mansour A. A., Caspi I., Krupalnik V., Zerbib M., Maza I., Mor N., Baran D., Weinberger L., Jaitin D. A., Lara-Astiaso D., Blecher-Gonen R., Shipony Z., Mukamel Z., Hagai T., Gilad S., Amann-Zalcenstein D., Tanay A., Amit I., Novershtern N. & Hanna J. H. (2015)
  • Editorial overview: Genome architecture and expression

    Panning B. & Segal E. (2015)
  • Editorial overview: Cell organelles: Organelle communication: new means and new views.

    Schuldiner M. (2015)
  • Corrective jitter motion shows similar individual frequencies for the arm and the finger

    Noy L., Alon U. & Friedman J. (2015)
  • Guanine polynucleotides are self-antigens for human natural autoantibodies and are significantly reduced in the human genome

    Fattal I., Shental N., Ben-Dor S., Molad Y., Gabrielli A., Pokroy-Shapira E., Oren S., Livneh A., Langevitz P., Zandman-Goddard G., Sarig O., Margalit R., Gafter U., Domany E. & Cohen I. R. (2015)
  • Symmetry Breaking in Homo-Oligomers: The Curious Case of Mega-Hemocyanin

    Seisdedos H. G., Steinberg A. & Levy E. D. (2015)
  • The Evolutionary Potential of Phenotypic Mutations

    Yanagida H., Gispan A., Kadouri N., Rozen S., Sharon M., Barkai N. & Tawfik D. S. (2015)
  • Metagenomic cross-talk: the regulatory interplay between immunogenomics and the microbiome.

    Levy M., Thaiss C. A. & Elinav E. (2015)
  • The Mass-Longevity Triangle: Pareto Optimality and the Geometry of Life-History Trait Space.

    Szekely P., Korem Y., Moran U., Mayo A. & Alon U. (2015)
  • Simultaneous measurement of genome-wide transcription elongation speeds and rates of RNA polymerase II transition into active elongation with 4sUDRB-seq

    Fuchs G., Voichek Y., Rabani M., Benjamin S., Gilad S., Amit I. & Oren M. (2015)
  • One library to make them all: Streamlining yeast library creation by a SWAp-Tag (SWAT) strategy

    Weill U., Yofe I., Chuartzman S. & Schuldiner M. (2015)
  • Chromosome 7 gain and DNA hypermethylation at the HOXA10 locus are associated with expression of a stem cell related HOX-signature in glioblastoma

    Kurscheid S., Bady P., Sciuscio D., Samarzija I., Shay T., Vassallo I., Criekinge W. V., Daniel R. T., van den Bent d. B. M. J., Marosi C., Weller M., Mason W. P., Domany E., Stupp R., Delorenzi M. & Hegi M. E. (2015)
  • Recurrent inactivating RASA2 mutations in melanoma

    Arafeh R., Qutob N., Emmanuel R., Keren-Paz A., Madore J., Elkahloun A., Wilmott J. S., Gartner J. J., Di Pizio A., Winograd-Katz S., Sindiri S., Rotkopf R., Dutton-Regester K., Johansson P., Pritchard A. L., Waddell N., Hill V. K., Lin J. C., Hevroni Y., Rosenberg S. A., Khan J., Ben-Dor S., Niv M. Y., Ulitsky I., Mann G. J., Scolyer R. A., Hayward N. K. & Samuels Y. (2015)
  • Bursty Gene Expression in the Intact Mammalian Liver

    Halpern K. B., Tanami S., Landen S., Chapal M., Szlak L., Hutzler A., Nizhberg A. & Itzkovitz S. (2015)
  • A novel regulator determines the extent of contacts between organelles

    Schuldiner M. (2015)
  • Genome-Wide Screens in Saccharomyces cerevisiae Highlight a Role for Cardiolipin in Biogenesis of Mitochondrial Outer Membrane Multispan Proteins.

    Sauerwald J., Jores T., Eisenberg-Bord M., Chuartzman S. G., Schuldiner M. & Rapaport D. (2015)
  • Artificial Sweeteners Induce Glucose Intolerance by Altering the Gut Microbiota: Editorial comment

    Suez J., Korem T., Zeevi D., Zilberman-Schapira G., Thaiss C. A., Maza O., Israeli D., Zmora N., Gilad S., Weinberger A., Kuperman Y., Harmelin A., Kolodkin-Gal I., Shapiro H., Halpern Z., Segal E. & Elinav E. (2015)
  • An In Vivo Metabolic Approach for Deciphering the Product Specificity of Glycerate Kinase Proves that Both E. coli's Glycerate Kinases Generate 2-Phosphoglycerate

    Zelcbuch L., Razo-Mejia M., Herz E., Yahav S., Antonovsky N., Kroytoro H., Milo R. & Bar-Even A. (2015)
  • The Lamarckian chicken and the Darwinian egg

    Pilpel Y. & Rechavi O. (2015)
  • CRISPR adaptation biases explain preference for acquisition of foreign DNA

    Levy A., Goren M. G., Yosef I., Auster O., Manor M., Amitai G., Edgar R., Qimron U. & Sorek R. (2015)
  • The interplay between the innate immune system and the microbiota

    Thaiss C. A., Levy M., Suez J. & Elinav E. (2014)
  • Pregnancy-Associated Listeriosis: Clinical Characteristics and Geospatial Analysis of a 10-Year Period in Israel

    Elinav H., Hershko-Klement A., Valinsky L., Jaffe J., Wiseman A., Shimon H., Braun E., Paitan Y., Block C., Sorek R. & Nir-Paz R. (2014)
  • Epstein-Barr virus antibodies mark systemic lupus erythematosus and scleroderma patients negative for anti-DNA

    Fattal I., Shental N., Molad Y., Gabrielli A., Pokroy-Shapira E., Oren S., Livneh A., Langevitz P., Pauzner R., Sarig O., Gafter U., Domany E. & Cohen I. R. (2014)
  • Aging-induced immunological signature of the brain's choroid plexus negatively regulates neurogenesis and cognitive function

    Deczkowska A., Baruch K., David E., Castellano J. M., Miller O., Kertser A., Berkutzki T., Barnett Itzhaki I. Z., Bezalel D., Wyss-coray T., Amit I. & Schwartz M. (2014)
  • A Comprehensive tRNA Deletion Library Unravels the Genetic Architecture of the tRNA Pool

    Bloom-Ackermann Z., Navon S., Gingold H., Towers R., Pilpel Y. & Dahan O. (2014)
  • Visual account of protein investment in cellular functions

    Liebermeister W., Noor E., Flamholz A., Davidi D., Bernhardt J. & Milo R. (2014)
  • Artificial sweeteners induce glucose intolerance by altering the gut microbiota

    Suez J., Korem T., Zeevi D., Zilberman-Schapira G., Thaiss C. A., Maza O., Israeli D., Zmora N., Gilad S., Weinberger A., Kuperman Y., Harmelin A., Kolodkin-Gal I., Shapiro H., Halpern Z., Segal E. & Elinav E. (2014)
  • Phenotypic noise: effects of post-transcriptional regulatory processes affecting mRNA

    Arbel-Goren R., Tal A. & Stavans J. (2014)
  • A shared architecture for promoters and enhancers

    Weingarten-Gabbay S. & Segal E. (2014)
  • Embracing the void-how much do we really know about targeting and translocation to the endoplasmic reticulum?

    Aviram N. & Schuldiner M. (2014)
  • In pursuit of design principles of regulatory sequences

    Levo M. & Segal E. (2014)
  • The emergence of proteome-wide technologies: systematic analysis of proteins comes of age

    Breker M. & Schuldiner M. (2014)
  • Fur Is the Master Regulator of the Extraintestinal Pathogenic Escherichia coli Response to Serum

    Huja S., Oren Y., Biran D., Meyer S., Dobrindt U., Bernhard J., Becher D., Hecker M., Sorek R. & Ron E. Z. (2014)
  • Peroxisomes are juxtaposed to strategic sites on mitochondria

    Cohen Y., Klug Y., Dimitrov L., Erez Z., Chuartzman S., Elinger D., Yofe I., Soliman K., Gartner J., Thoms S., Schekman R., Elbaz-Alon Y., Zalckvar E. & Schuldiner M. (2014)
  • Host-parasite network structure is associated with community-level immunogenetic diversity

    Pilosof S., Fortuna M. A., Cosson J., Galan M., Kittipong C., Ribas A., Segal E., Krasnov B. R., Morand S. & Bascompte J. (2014)
  • Molecular Rules Governing De Novo Methylation in Cancer

    Nejman D., Straussman R., Steinfeld I., Ruvolo M., Roberts D., Yakhini Z. & Cedar H. (2014)
  • Single cell analysis exposes intratumor heterogeneity and suggests that FLT3-ITD is a late event in leukemogenesis

    Shouval R., Shlush L. I., Yehudai-Resheff S., Ali S., Pery N., Shapiro E., Tzukerman M., Rowe J. M. & Zuckerman T. (2014)
  • Plasticity in the transcriptional and epigenetic circuits regulating dendritic cell lineage specification and function

    Paul F. & Amit I. (2014)
  • Identification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin

    Ziv O., Zeisel A., Mirlas-Neisberg N., Swain U., Nevo R., Ben Chetrit C. N., Martelli M. P., Rossi R., Schiesser S., Canman C. E., Carell T., Geacintov N. E., Falini B., Domany E. & Livneh Z. (2014)
  • Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

    Jaitin D. A., Kenigsberg E., Keren-Shaul H., Elefant N., Paul F., Zaretsky I., Mildner A., Cohen N., Jung S., Tanay A. & Amit I. (2014)
  • Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5 ' Sites

    Schwartz S., Mumbach M. R., Jovanovic M., Wang T., Maciag K., Bushkin G. G., Mertins P., Ter-Ovanesyan D., Habib N., Cacchiarelli D., Sanjana N. E., Freinkman E., Pacold M. E., Satija R., Mikkelsen T. S., Hacohen N., Zhang F., Carr S. A., Lander E. S. & Regev A. (2014)
  • A simple cage-autonomous method for the maintenance of the barrier status of germ-free mice during experimentation

    Hecht G., Bar-Nathan C., Milite G., Alon I., Moshe Y., Greenfeld L., Dotsenko N., Suez J., Levy M., Thaiss C. A., Dafni H., Elinav E. & Harmelin A. (2014)
  • Genetic and Phenotypic Diversity in Breast Tumor Metastases

    Almendro V., Kim H. J., Cheng Y., Goenen M., Itzkovitz S., Argani P., van Oudenaarden O. A., Sukumar S., Michor F. & Polyak K. (2014)
  • The role of chromatin dynamics in immune cell development

    Winter D. R. & Amit I. (2014)
  • Inflammasomes and Metabolic Disease

    Henao-Mejia J., Elinav E., Thaiss C. A. & Flavell R. (2014)
  • Reply to Metson et al.: The importance of phosphorus perturbations

    Eshel G., Shepon A., Makov T. & Milo R. (2014)
  • A Fundamental Trade-off in Covalent Switching and Its Circumvention by Enzyme Bifunctionality in Glucose Homeostasis

    Dasgupta T., Croll D. H., Owen J. A., Vander Heiden H. M. G., Locasale J. W., Alon U., Cantley L. C. & Gunawardena J. (2014)
  • 4sUDRB-seq: measuring genomewide transcriptional elongation rates and initiation frequencies within cells

    Fuchs G., Voichek Y., Benjamin S., Gilad S., Amit I. & Oren M. (2014)
  • The yeast oligopeptide transporter Opt2 is localized to peroxisomes and affects glutathione redox homeostasis

    Elbaz-Alon Y., Morgan B., Clancy A., Amoako T. N. E., Zalckvar E., Dick T. P., Schwappach B. & Schuldiner M. (2014)
  • KSHV 2.0: A Comprehensive Annotation of the Kaposi's Sarcoma-Associated Herpesvirus Genome Using NextGeneration Sequencing Reveals Novel Genomic and Functional Features

    Arias C., Weisburd B., Stern-Ginossar N., Mercier A., Madrid A. S., Bellare P., Holdorf M., Weissman J. S. & Ganem D. (2014)
  • Scaling of dorsal-ventral patterning in the Xenopus laevis embryo

    Ben-Zvi D., Fainsod A., Shilo B. & Barkai N. (2014)
  • Probing the effect of promoters on noise in gene expression using thousands of designed sequences

    Sharon E., Van Dijk D. D., Kalma Y., Keren L., Manor O., Yakhini Z. & Segal E. (2014)
  • COMBINATION OF GENE COPY GAIN AND EPIGENETIC DEREGULATION ARE ASSOCIATED WITH THE ABERRANT EXPRESSION OF A STEM CELL RELATED HOX-SIGNATURE IN GLIOBLASTOMA

    Kurscheid S., Bady P., Sciuscio D., Samarzija I., Shay T., Vassallo I., Van Criekinge C. W., Domany E., Stupp R., Delorenzi M. & Hegi M. (2014)
  • Primers-4-Yeast: a comprehensive web tool for planning primers for Saccharomyces cerevisiae

    Yofe I. & Schuldiner M. (2014)
  • Divergence and Selectivity of Expression-Coupled Histone Modifications in Budding Yeasts

    Mosesson Y., Voichek Y. & Barkai N. (2014)
  • A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation

    Gingold H., Tehler D., Christoffersen N., Nielsen M., Asmar F., Kooistra S., Christophersen N., Christensen L., Borre M., Sorensen K., Andersen L., Andersen C., Hulleman E., Wurdinger T., Ralfkiaer E., Helin K., Gronbaek K., Omtoft T., Waszak S., Dahan O., Pedersen J., Lund A. & Pilpel Y. (2014)
  • Diurnal suppression of EGFR signalling by glucocorticoids and implications for tumour progression and treatment

    Lauriola M., Enuka Y., Zeisel A., D'Uva G., Roth L., Sharon-Sevilla M., Lindzen M., Sharma K., Nevo N., Carvalho S., Cohen-Dvashi H., Kedmi M., Ben Chetrit C. N., Chen A., Solmi R., Wiemann S., Schmitt F., Domany E. & Yarden Y. (2014)
  • Point of View: Correcting the bias against interdisciplinary research

    Shapiro E. (2014)
  • Digital cell quantification identifies global immune cell dynamics during influenza infection

    Altboum Z., Steuerman Y., David E., Barnett Itzhaki I. Z., Valadarsky L., Keren-Shaul H., Meningher T., Mendelson E., Mandelboim M., Gat-Viks I. & Amit I. (2014)
  • Loss of growth homeostasis by genetic decoupling of cell division from biomass growth: implication for size control mechanisms

    Schmidt-Glenewinkel H. & Barkai N. (2014)
  • Lucky iPSCs

    Zviran A. & Hanna J. (2014)
  • Land, irrigation water, greenhouse gas, and reactive nitrogen burdens of meat, eggs, and dairy production in the United States

    Eshel G., Shepon A., Makov T. & Milo R. (2014)
  • Pemphigus vulgaris is characterized by low IgG reactivities to specific self-antigens along with high IgG reactivity to desmoglein 3

    Fattal I., Rimer J., Shental N., Molad Y., Gabrielli A., Livneh A., Sarig O., Goldberg I., Gafter U., Domany E. & Cohen I. R. (2014)
  • A Dynamic Interface between Vacuoles and Mitochondria in Yeast

    Elbaz-Alon Y., Rosenfeld-Gur E., Shinder V., Futerman A. H., Geiger T. & Schuldiner M. (2014)
  • Scaling morphogen gradients during tissue growth by a cell division rule

    Averbukh I., Ben-Zvi D., Mishra S. & Barkai N. (2014)
  • A defect in the RNA-processing protein HNRPDL causes limb-girdle muscular dystrophy 1G (LGMD1G)

    Vieira N. M., Naslavsky M. S., Licinio L., Kok F., Schlesinger D., Vainzof M., Sanchez N., Kitajima J. P., Gal L., Cavacana N., Serafini P. R., Chuartzman S., Vasquez C., Mimbacas A., Nigro V., Pavanello R. C., Schuldiner M., Kunkel L. M. & Zatz M. (2014)
  • Heuristic for Maximizing DNA Reuse in Synthetic DNA Library Assembly

    Blakes J., Raz O., Feige U., Bacardit J., Widera P., Ben-Yehezkel T., Shapiro E. & Krasnogor N. (2014)
  • Intratumor DNA Methylation Heterogeneity Reflects Clonal Evolution in Aggressive Prostate Cancer

    Brocks D., Assenov Y., Minner S., Bogatyrova O., Simon R., Koop C., Oakes C., Zucknick M., Lipka D. B., Weischenfeldt J., Feuerbach L., Lari R. C., Lupien M., Brors B., Korbel J., Schlomm T., Tanay A., Sauter G., Gerhaeuser C. & Plass C. (2014)
  • Sequestration of a two-component response regulator by a riboswitch-regulated noncoding RNA

    Mellin J. R., Koutero M., Dar D., Nahori M., Sorek R. & Cossart P. (2014)
  • miR-661 downregulates both Mdm2 and Mdm4 to activate p53

    Hoffman Y., Bublik D. R., Pilpel Y. & Oren M. (2014)
  • Location of the unique integration site on an Escherichia coli chromosome by bacteriophage lambda DNA in vivo

    Tal A., Arbel-Goren R., Costantino N., Court D. L. & Stavans J. (2014)
  • The quantified cell

    Flamholz A., Phillips R. & Milo R. (2014)
  • Linear Superposition and Prediction of Bacterial Promoter Activity Dynamics in Complex Conditions

    Rothschild D., Dekel E., Hausser J., Bren A., Aidelberg G., Szekely P. & Alon U. (2014)
  • All roads lead to Rome-SRP independent translocation into the endoplasmic reticulum

    Ast T. & Schuldiner M. (2014)
  • The grammar of transcriptional regulation

    Weingarten-Gabbay S. & Segal E. (2014)
  • Pathway Thermodynamics Highlights Kinetic Obstacles in Central Metabolism

    Noor E., Bar-Even A., Flamholz A., Reznik E., Liebermeister W. & Milo R. (2014)
  • Paradoxical Signaling by a Secreted Molecule Leads to Homeostasis of Cell Levels

    Hart Y., Reich-Zeliger S., Antebi Y. E., Zaretsky I., Mayo A. E., Alon U. & Friedman N. (2014)
  • Expansion of CD16 positive and negative human NK cells in response to tumor stimulation

    Tsukerman P., Stern-Ginossar N., Yamin R., Ophir Y., Miller A., Stanietsky N. & Mandelboim O. (2014)
  • The Fire Within: Microbes Inflame Tumors

    Gagliani N., Hu B., Huber S., Elinav E. & Flavell R. A. (2014)
  • Transkingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis

    Thaiss C. A., Zeevi D., Levy M., Zilberman-Schapira G., Suez J., Tengeler A. C., Abramson L., Katz M. N., Korem T., Zmora N., Kuperman Y., Biton I., Gilad S., Harmelin A., Shapiro H., Halpern Z., Segal E. & Elinav E. (2014)
  • The Back and Forth of Cargo Exit from the Endoplasmic Reticulum

    Geva Y. & Schuldiner M. (2014)
  • Yeast phospholipid biosynthesis is linked to mRNA localization

    Hermesh O., Genz C., Yofe I., Sinzel M., Rapaport D., Schuldiner M. & Jansen R. (2014)
  • Inference of Tumor Evolution during Chemotherapy by Computational Modeling and In Situ Analysis of Genetic and Phenotypic Cellular Diversity

    Almendro V., Cheng Y., Randles A., Itzkovitz S., Marusyk A., Ametller E., Gonzalez-Farre X., Munoz M., Russnes H. G., Helland A., Rye I. H., Borresen-Dale A., Maruyama R., van Oudenaarden O. A., Dowsett M., Jones R. L., Reis-Filho J., Gascon P. & Goenen M. (2014)
  • A cytosolic degradation pathway, prERAD, monitors pre-inserted secretory pathway proteins

    Ast T., Aviram N., Chuartzman S. G. & Schuldiner M. (2014)
  • Different subunits belonging to the same protein complex often exhibit discordant expression levels and evolutionary properties

    Matalon O., Horovitz A. & Levy E. D. (2014)
  • Passage Number is a Major Contributor to Genomic Structural Variations in Mouse iPSCs

    Liu P., Kaplan A., Yuan B., Hanna J. H., Lupski J. R. & Reiner O. (2014)
  • Sequential Feedback Induction Stabilizes the Phosphate Starvation Response in Budding Yeast

    Vardi N., Levy S., Gurvich Y., Polacheck T., Carmi M., Jaitin D., Amit I. & Barkai N. (2014)
  • Molecular dissection of the genetic mechanisms that underlie expression conservation in orthologous yeast ribosomal promoters

    Zeevi D., Lubliner S., Lotan-Pompan M., Hodis E., Vesterman R., Weinberger A. & Segal E. (2014)
  • Hierarchy of non-glucose sugars in Escherichia coli

    Aidelberg G., Towbin B. D., Rothschild D., Dekel E., Bren A. & Alon U. (2014)
  • High-resolution metagenomics

    Mick E. & Sorek R. (2014)
  • The cross talk between microbiota and the immune system: metabolites take center stage

    Shapiro H., Thaiss C. A., Levy M. & Elinav E. (2014)
  • Accurate, Model-Based Tuning of Synthetic Gene Expression Using Introns in S. cerevisiae

    Yofe I., Zafrir Z., Blau R., Schuldiner M., Tuller T., Shapiro E. & Ben-Yehezkel T. (2014)
  • Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA

    Schwartz S., Bernstein D. A., Mumbach M. R., Jovanovic M., Herbst R. H., Leon-Ricardo B. X., Engreitz J. M., Guttman M., Satija R., Lander E. S., Fink G. & Regev A. (2014)
  • Checkpoint-independent scaling of the Saccharomyces cerevisiae DNA replication program

    Gispan A., Carmi M. & Barkai N. (2014)
  • Single-cell RNA-seq reveals dynamic paracrine control of cellular variation

    Shalek A. K., Satija R., Shuga J., Trombetta J. J., Gennert D., Lu D., Chen P., Gertner R. S., Gaublomme J. T., Yosef N., Schwartz S., Fowler B., Weaver S., Wang J., Wang X., Ding R., Raychowdhury R., Friedman N., Hacohen N., Park H., May A. P. & Regev A. (2014)
  • OM14 is a mitochondrial receptor for cytosolic ribosomes that supports co-translational import into mitochondria

    Lesnik C., Cohen Y., Atir-Lande A., Schuldiner M. & Arava Y. (2014)
  • The central nervous system microenvironment imprints microglial inability to switch from pro- to anti-inflammatory phenotype

    Matcovitch O., Cohen M., David E., Barnettitzhaki Z., Keren-Shaul H., Blecher-gonen R., Jaitin D. A., Sica A., Amit I. & Schwartz M. (2014)
  • Systematic identification of cell size regulators in budding yeast

    Soifer I. & Barkai N. (2014)
  • The PH gene determines fruit acidity and contributes to the evolution of sweet melons

    Cohen S., Itkin M., Yeselson Y., Tzuri G., Portnoy V., Harel-Baja R., Lev S., Sa'ar U., Davidovitz-Rikanati R., Baranes N., Bar E., Wolf D., Petreikov M., Shen S., Ben-Dor S., Rogachev I., Aharoni A., Ast T., Schuldiner M., Belausov E., Eshed R., Ophir R., Sherman A., Frei B., Neuhaus H. E., Xu Y., Fei Z., Giovannoni J., Lewinsohn E., Tadmor Y., Paris H. S., Katzir N., Burger Y. & Schaffer A. A. (2014)
  • mRNA-programmed translation pauses in the targeting of E. coli membrane proteins.

    Fluman N., Navon S., Bibi E. & Pilpel Y. (2014)
  • Ribosome Profiling Reveals Pervasive Translation Outside of Annotated Protein-Coding Genes

    Ingolia N. T., Brar G. A., Stern-Ginossar N., Harris M. S., Talhouarne G. J. S., Jackson S. E., Wills M. R. & Weissman J. S. (2014)
  • Novel Superactive Leptin Antagonists and their Potential Therapeutic Applications

    Gertler A. & Elinav E. (2014)
  • High-Resolution Mapping of Protein Concentration Reveals Principles of Proteome Architecture and Adaptation

    Levy E. D., Kowarzyk J. & Michnick S. W. (2014)
  • Chronic exposure to TGF beta 1 regulates myeloid cell inflammatory response in an IRF7-dependent manner

    Cohen M., Matcovitch O., David E., Barnett Itzhaki I. Z., Keren-Shaul H., Blecher-Gonen R., Jaitin D. A., Sica A., Amit I. & Schwartz M. (2014)
  • Dynamic and static maintenance of epigenetic memory in pluripotent and somatic cells

    Shipony Z., Mukamel Z., Cohen N. M., Landan G., Chomsky E., Zeliger S. R., Fried Y. C., Ainbinder E., Friedman N. & Tanay A. (2014)
  • Coordination of Gene Expression and Growth-Rate in Natural Populations of Budding Yeast

    Tamari Z., Rosin D., Voichek Y. & Barkai N. (2014)
  • Individuality and Togetherness in Joint Improvised Motion

    Hart Y., Noy L., Feniger-Schaal R., Mayo A. & Alon U. (2014)
  • Analysis of the transcriptional networks underpinning the activation of murine macrophages by inflammatory mediators

    Raza S., Barnett M. W., Barnett Itzhaki I. Z., Amit I., Hume D. A. & Freeman T. C. (2014)
  • Lineage grammars: describing, simulating and analyzing population dynamics

    Spiro A., Cardelli L. & Shapiro E. (2014)
  • NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion

    Wlodarska M., Thaiss C. A., Nowarski R., Henao-Mejia J., Zhang J., Brown E. M., Frankel G., Levy M., Katz M. N., Philbrick W. M., Elinav E., Finlay B. B. & Flavell R. A. (2014)
  • microRNAs and Alu elements in the p53-Mdm2-Mdm4 regulatory network

    Hoffman Y., Pilpel Y. & Oren M. (2014)
  • Aging-induced type I interferon response at the choroid plexus negatively affects brain function

    Baruch K., Deczkowska A., David E., Castellano J. M., Miller O., Kertser A., Berkutzki T., Barnett Itzhaki I. Z., Bezalel D., Wyss-Coray T., Amit I. & Schwartz M. (2014)
  • The Biggest Challenges Facing Young Scientists

    Keays D., Barreiro L., Stuart-Fox D., Brar G., Schuldiner M. & Tahiliani M. (2014)
  • Cooperativity, Specificity, and Evolutionary Stability of Polycomb Targeting in Drosophila

    Schuettengruber B., Elkayam N. O., Sexton T., Entrevan M., Stern S., Thomas A., Yaffe E., Parrinello H., Tanay A. & Cavalli G. (2014)
  • Noise Genetics: Inferring Protein Function by Correlating Phenotype with Protein Levels and Localization in Individual Human Cells

    Farkash-Amar S., Zimmer A., Eden E., Cohen A., Geva Zatorsky Z. N., Cohen L., Milo R., Sigal A., Danon T. & Alon U. (2014)
  • A Negative Feedback Loop of Transcription Factors Specifies Alternative Dendritic Cell Chromatin States

    Bornstein C., Winter D., Barnett Itzhaki I. Z., David E., Kadri S., Garber M. & Amit I. (2014)
  • Using High-Throughput Transcriptomic Data for Prognosis: A Critical Overview and Perspectives

    Domany E. (2014)
  • The Yeast ER-Intramembrane Protease Ypf1 Refines Nutrient Sensing by Regulating Transporter Abundance

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  • Subcellular Transcriptomics-Dissection of the mRNA Composition in the Axonal Compartment of Sensory Neurons

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  • Promoter Sequence Determines the Relationship between Expression Level and Noise

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  • Characterization of an M28 metalloprotease family member residing in the yeast vacuole

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  • Measurements of the Impact of 3 ' End Sequences on Gene Expression Reveal Wide Range and Sequence Dependent Effects

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  • Discovery of Functional Toxin/Antitoxin Systems in Bacteria by Shotgun Cloning

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  • Design and analysis of metabolic pathways supporting formatotrophic growth for electricity-dependent cultivation of microbes

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  • High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis

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  • A Global Transcriptional Switch between the Attack and Growth Forms of Bdellovibrio bacteriovorus

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  • The Yeast P5 Type ATPase, Spf1, Regulates Manganese Transport into the Endoplasmic Reticulum

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  • A versatile genome-scale PCR-based pipeline for high-definition DNA FISH

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  • Computational evaluation of cellular metabolic costs successfully predicts genes whose expression is deleterious

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  • Robust Prediction of Expression Differences among Human Individuals Using Only Genotype Information

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  • Oct4 shuffles Sox partners to direct cell fate

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  • Predicting Disease Risk Using Bootstrap Ranking and Classification Algorithms

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  • The Expression of the Beta Cell-Derived Autoimmune Ligand for the Killer Receptor Nkp46 Is Attenuated in Type 2 Diabetes

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  • The Contribution of Systematic Approaches to Characterizing the Proteins and Functions of the Endoplasmic Reticulum

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  • The Role of Djp1 in Import of the Mitochondrial Protein Mim1 Demonstrates Specificity between a Cochaperone and Its Substrate Protein

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  • Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli

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  • A new algorithm for combinatorial dna library assembly

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  • Harnessing Nanomedicine for Mucosal Theranostics-A Silver Bullet at Last?

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  • Differential Translation Tunes Uneven Production of Operon-Encoded Proteins

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  • The last generation of bacterial growth in limiting nutrient

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  • Holding a grudge: Persisting anti-phage CRISPR immunity in multiple human gut microbiomes

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  • Glycolytic strategy as a tradeoff between energy yield and protein cost

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  • Fixated on fixation: using ChIP to interrogate the dynamics of chromatin interactions

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  • Evolutionary Tradeoffs between Economy and Effectiveness in Biological Homeostasis Systems

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  • The majority of endogenous microRNA targets within Alu elements avoid the microRNA machinery

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  • Deterministic direct reprogramming of somatic cells to pluripotency

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  • The Intestinal Microbiota in Chronic Liver Disease

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  • The geometry of the Pareto front in biological phenotype space

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  • Budding Yeast Escape Commitment to the Phosphate Starvation Program Using Gene Expression Noise

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  • Developmental bias in the evolution of phalanges

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  • Mutation Rules and the Evolution of Sparseness and Modularity in Biological Systems

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  • Semiconductor-based DNA sequencing of histone modification states

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  • A note on the kinetics of enzyme action: A decomposition that highlights thermodynamic effects

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  • Inferring gene expression from ribosomal promoter sequences, a crowdsourcing approach

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  • RNF20 and USP44 Regulate Stem Cell Differentiation by Modulating H2B Monoubiquitylation

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  • Tracing the genesis of human embryonic stem cells

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  • Extensive alternative polyadenylation during zebrafish development

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  • Modeling ductal carcinoma in situ: a HER2-Notch3 collaboration enables luminal filling

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  • Expression Noise and Acetylation Profiles Distinguish HDAC Functions

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  • Regulation of signalling by microRNAs

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  • A mechanical Turing machine: blueprint for a biomolecular computer

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  • Changes in exon-intron structure during vertebrate evolution affect the splicing pattern of exons

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  • Protein abundance is key to distinguish promiscuous from functional phosphorylation based on evolutionary information

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  • Surface Growth of a Motile Bacterial Population Resembles Growth in a Chemostat

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  • Chromosomal duplication is a transient evolutionary solution to stress

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  • Axonal transcription factors signal retrogradely in lesioned peripheral nerve

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  • Efficiency in Evolutionary Trade-Offs

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  • Silencing of a large microRNA cluster on human chromosome 14q32 in melanoma: biological effects of mir-376a and mir-376c on insulin growth factor 1 receptor

    Zehavi L., Avraham R., Barzilai A., Bar-Ilan D., Navon R., Sidi Y., Avni D. & Leibowitz-Amit R. (2012)
  • Ergosterol content specifies targeting of tail-anchored proteins to mitochondrial outer membranes

    Krumpe K., Frumkin I., Herzig Y., Rimon N., Oezbalci C., Bruegger B., Rapaport D. & Schuldiner M. (2012)
  • Design principles of cell circuits with paradoxical components

    Hart Y., Antebi Y. E., Mayo A. E., Friedman N. & Alon U. (2012)
  • Dynamic Proteomics of Human Protein Level and Localization across the Cell Cycle

    Farkash-Amar S., Eden E., Cohen A., Geva Zatorsky Z. N., Cohen L., Milo R., Sigal A., Danon T. & Alon U. (2012)
  • Thermodynamic constraints shape the structure of carbon fixation pathways

    Bar-Even A., Flamholz A., Noor E. & Milo R. (2012)
  • A Systematic Approach to Pair Secretory Cargo Receptors with Their Cargo Suggests a Mechanism for Cargo Selection by Erv14

    Herzig Y., Sharpe H. J., Elbaz Y., Munro S. & Schuldiner M. (2012)
  • Modeling invasive breast cancer: growth factors propel progression of HER2-positive premalignant lesions

    Pradeep C., Zeisel A., Koestler W. J., Lauriola M., Jacob-Hirsch J., Haibe-Kains B., Amariglio N., Ben Chetrit C. N., Emde A. M., Solomonov I., Neufeld G., Piccart M., Sagi I., Sotiriou C., Rechavi G., Domany E., Desmedt C. & Yarden Y. (2012)
  • Clonal allelic predetermination of immunoglobulin-kappa rearrangement

    Farago M., Rosenbluh C., Tevlin M., Fraenkel S., Schlesinger S., Masika H., Gouzman M., Teng G., Schatz D., Rais Y., Hanna J. H., Mildner A., Jung S., Mostoslavsky G., Cedar H. & Bergman Y. (2012)
  • The Single-Nucleotide Resolution Transcriptome of Pseudomonas aeruginosa Grown in Body Temperature

    Wurtzel O., Yoder-Himes D. R., Han K., Dandekar A. A., Edelheit S., Greenberg E. P., Sorek R. & Lory S. (2012)
  • New insights into replication origin characteristics in metazoans

    Cayrou C., Coulombe P., Puy A., Rialle S., Kaplan N., Segal E. & Mechali M. (2012)
  • A vast collection of microbial genes that are toxic to bacteria

    Kimelman A., Levy A., Sberro H., Kidron S., Leavitt A., Amitai G., Yoder-Himes D. R., Wurtzel O., Zhu Y., Rubin E. M. & Sorek R. (2012)
  • Widespread promoter-mediated coordination of transcription and mRNA degradation

    Dori-Bachash M., Shalem O., Manor Y. S., Pilpel Y. & Tirosh I. (2012)
  • The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming

    Mansour A. A., Gafni O., Weinberger L., Zviran A., Ayyash M., Rais Y., Krupalnik V., Zerbib M., Amann Zalcenstein Z. D., Maza I., Geula S., Viukov S., Holtzman L., Pribluda A., Canaani E., Horn-Saban S., Amit I., Novershtern N. & Hanna J. H. (2012)
  • Transcriptome-wide discovery of circular RNAs in Archaea

    Danan M., Schwartz S., Edelheit S. & Sorek R. (2012)
  • Topology of the human and mouse m(6)A RNA methylomes revealed by m(6)A-seq

    Dominissini D., Moshitch-Moshkovitz S., Schwartz S., Salmon-Divon M., Ungar L., Osenberg S., Cesarkas K., Jacob-Hirsch J., Amariglio N., Kupiec M., Sorek R. & Rechavi G. (2012)
  • From catalogue to function

    Segal E. (2012)
  • Dynamic changes in translational efficiency are deduced from codon usage of the transcriptome

    Gingold H., Dahan O. & Pilpel Y. (2012)
  • Decoding Human Cytomegalovirus

    Stern-Ginossar N., Weisburd B., Michalski A., Vu Thuy Khanh Le, Hein M. Y., Huang S., Ma M., Shen B., Qian S., Hengel H., Mann M., Ingolia N. T. & Weissman J. S. (2012)
  • Functional Consequences of Necdin Nucleocytoplasmic Localization

    Lavi-Itzkovitz A., Tcherpakov M., Levy Z., Itzkovitz S., Muscatelli F. & Fainzilber M. (2012)
  • Recursive construction of perfect DNA molecules and libraries from imperfect oligonucleotides

    Linshiz G., Yehezkel T. B. & Shapiro E. (2012)
  • Interactions of subunit CCT3 in the yeast chaperonin CCT/TRiC with Q/N-rich proteins revealed by high-throughput microscopy analysis

    Nadler Holly H. M., Breker M., Gruber R., Azia A., Gymrek M., Eisenstein M., Willison K. R., Schuldiner M. & Horovitz A. (2012)
  • Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters

    Sharon E., Kalma Y., Sharp A., Raveh - Sadka -. S. T., Levo M., Zeevi D., Keren L., Yakhini Z., Weinberger A. & Segal E. (2012)
  • Promoter Nucleosome Organization Shapes the Evolution of Gene Expression

    Rosin D., Hornung G., Tirosh I., Gispan A. & Barkai N. (2012)
  • Robust 4C-seq data analysis to screen for regulatory DNA interactions

    van de Werken d. W. H. J. G., Landan G., Holwerda S. J. B., Hoichman M., Klous P., Chachik R., Splinter E., Valdes-Quezada C., Oz Y., Bouwman B. A. M., Verstegen M. J. A. M., de Wit W. E., Tanay A. & de Laat L. W. (2012)
  • A proof for loop-law constraints in stoichiometric metabolic networks

    Noor E., Lewis N. E. & Milo R. (2012)
  • RNA-seq analysis of small RNPs in Trypanosoma brucei reveals a rich repertoire of non-coding RNAs

    Michaeli S., Doniger T., Gupta S. K., Wurtzel O., Romano M., Visnovezky D., Sorek R., Unger R. & Ullu E. (2012)
  • A Crossroad of microRNAs and Immediate Early Genes (IEGs) Encoding Oncogenic Transcription Factors in Breast Cancer

    Sas-Chen A., Avraham R. & Yarden Y. (2012)
  • Cell lineage analysis of acute leukemia relapse uncovers the role of replication-rate heterogeneity and microsatellite instability

    Shlush L. I., Chapal Ilani I. N., Adar R., Pery N., Maruvka Y., Spiro A., Shouval R., Rowe J. M., Tzukerman M., Bercovich D., Izraeli S., Marcucci G., Bloomfield C. D., Zuckerman T., Skorecki K. & Shapiro E. (2012)
  • miR-10b*, a master inhibitor of the cell cycle, is down-regulated in human breast tumours

    Biagioni F., Ben-Moshe N. B., Fontemaggi G., Canu V., Mori F., Antoniani B., Di Benedetto B. A., Santoro R., Germoni S., De Angelis A. F., Cambria A., Avraham R., Grasso G., Strano S., Muti P., Mottolese M., Yarden Y., Domany E. & Blandino G. (2012)
  • Cell Lineage Analysis of the Mammalian Female Germline

    Reizel Y., Itzkovitz S., Adar R., Elbaz J., Jinich A., Chapal Ilani I. N., Maruvka Y. E., Nevo N., Marx Z., Horovitz I., Wasserstrom A., Mayo A., Shur I., Benayahu D., Skorecki K., Segal E., Dekel N. & Shapiro E. (2012)
  • Using bleach-chase to measure protein half-lives in living cells

    Geva Zatorsky Z. N., Issaeva I., Mayo A., Cohen A., Dekel E., Danon T., Cohen L., Liron Y., Alon U. & Eden E. (2012)
  • Achieving Diversity in the Face of Constraints: Lessons from Metabolism

    Milo R. & Last R. L. (2012)
  • Disentangling signaling gradients generated by equivalent sources

    Rappaport N. & Barkai N. (2012)
  • eQuilibrator: the biochemical thermodynamics calculator

    Flamholz A., Noor E., Bar-Even A. & Milo R. (2012)
  • Teasing Apart Translational and Transcriptional Components of Stochastic Variations in Eukaryotic Gene Expression

    Salari R., Wojtowicz D., Zheng J., Levens D., Pilpel Y. & Przytycka T. M. (2012)
  • A survey of carbon fixation pathways through a quantitative lens

    Bar-Even A., Noor E. & Milo R. (2012)
  • Mode of Regulation and the Insulation of Bacterial Gene Expression

    Sasson V., Shachrai I., Bren A., Dekel E. & Alon U. (2012)
  • Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

    Shibue T., Tischler V., Reinhardt F., Itzkovitz S., Noske A., Zuerrer-Haerdi U., Bell G., Tam W. L., Mani S. A., van Oudenaarden O. A. & Weinberg R. A. (2012)
  • EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF

    Tarcic G., Avraham R., Pines G., Amit I., Shay T., Lu Y., Zwang Y., Katz M., Ben Chetrit C. N., Jacob-Hirsch J., Virgilio L., Rechavi G., Mavrothalassitis G., Mills G. B., Domany E. & Yarden Y. (2012)
  • A Critical Role for the Wnt Effector Tcf4 in Adult Intestinal Homeostatic Self-Renewal

    Itzkovitz S., Koo B., Boj S. F., Korving J., van den Born d. B. M., van Oudenaarden O. A., Robine S. & Clevers H. (2012)
  • Noise-mean relationship in mutated promoters

    Hornung G., Bar-Ziv R., Rosin D., Tokuriki N., Tawfik D., Oren M. & Barkai N. (2012)
  • Identification of CTCF as a master regulator of the clustered protocadherin genes

    Golan Mashiach M. M., Grunspan M., Emmanuel R., Gibbs-Bar L., Dikstein R. & Shapiro E. (2012)
  • An integrated open framework for thermodynamics of reactions that combines accuracy and coverage

    Noor E., Bar-Even A., Flamholz A., Lubling Y., Davidi D. & Milo R. (2012)
  • Differential GC Content between Exons and Introns Establishes Distinct Strategies of Splice-Site Recognition

    Amit M., Donyo M., Hollander D., Goren A., Kim E., Gelfman S., Lev-Maor G., Burstein D., Schwartz S., Postolsky B., Pupko T. & Ast G. (2012)
  • Context-specific microRNA analysis: identification of functional microRNAs and their mRNA targets

    Ben-Moshe N. B., Avraham R., Kedmi M., Zeisel A., Yitzhaky A., Yarden Y. & Domany E. (2012)
  • Confinement to Organelle-Associated Inclusion Structures Mediates Asymmetric Inheritance of Aggregated Protein in Budding Yeast

    Spokoini R., Moldavski O., Nahmias Y., England J. L., Schuldiner M. & Kaganovich D. (2012)
  • Correction: Programmable In Vivo Selection of Arbitrary DNA Sequences

    Ben-Yehezkel T., Biezuner T., Linshiz G., Mazor Y. & Shapiro E. (2012)
  • Evolutionary Trade-Offs, Pareto Optimality, and the Geometry of Phenotype Space

    Shoval O., Sheftel H., Shinar G., Hart Y., Ramote O., Mayo A., Dekel E., Kavanagh K. & Alon U. (2012)
  • Genome-wide Measurement of RNA Folding Energies

    Wan Y., Qu K., Ouyang Z., Kertesz M., Li J., Tibshirani R., Makino D. L., Nutter R. C., Segal E. & Chang H. Y. (2012)
  • CRISPR targeting reveals a reservoir of common phages associated with the human gut microbiome

    Stern A., Mick E., Tirosh I., Sagy O. & Sorek R. (2012)
  • Inferring Divergence of Context-Dependent Substitution Rates in Drosophila Genomes with Applications to Comparative Genomics

    Chachick R. & Tanay A. (2012)
  • Rethinking glycolysis: on the biochemical logic of metabolic pathways

    Bar-Even A., Flamholz A., Noor E. & Milo R. (2012)
  • The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers

    van de Wetering d. W. M., Koo B., Itzkovitz S., Volckmann R., Kung K. S., Koster J., Radulescu S., Myant K., Versteeg R., Sansom O. J., van Es E. J. H., Barker N., van Oudenaarden O. A., Mohammed S., Heck A. J. R. & Clevers H. (2012)
  • Self-Organized Shuttling: Generating Sharp Dorsoventral Polarity in the Early Drosophila Embryo

    Haskel Ittah I. M., Ben-Zvi D., Branski Arieli A. M., Schejter E. D., Shilo B. & Barkai N. (2012)
  • Nucleosome Organization Affects the Sensitivity of Gene Expression to Promoter Mutations

    Hornung G., Oren M. & Barkai N. (2012)
  • MiR-10b Downregulates the Stress-Induced Cell Surface Molecule MICB, a Critical Ligand for Cancer Cell Recognition by Natural Killer Cells

    Tsukerman P., Stern-Ginossar N., Gur C., Glasner A., Nachmani D., Bauman Y., Yamin R., Vitenshtein A., Stanietsky N., Bar-Mag T., Lankry D. & Mandelboim O. (2012)
  • Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeast

    Raveh - Sadka -. S. T., Levo M., Shabi U., Shany B., Keren L., Lotan-Pompan M., Zeevi D., Sharon E., Weinberger A. & Segal E. (2012)
  • A programmable NOR-based device for transcription profile analysis

    Ran T., Douek Y., Milo L. & Shapiro E. (2012)
  • M(odu)LLating the Innate Response

    Blecher-Gonen R. & Amit I. (2012)
  • Efficiency and specificity in microRNA biogenesis

    Barad O., Mann M., Chapnik E., Shenoy A., Blelloch R., Barkai N. & Hornstein E. (2012)
  • Three-Dimensional Folding and Functional Organization Principles of the Drosophila Genome

    Sexton T., Yaffe E., Kenigsberg E., Bantignies F., Leblanc B., Hoichman M., Parrinello H., Tanay A. & Cavalli G. (2012)
  • Prediction of Microbial Growth Rate versus Biomass Yield by a Metabolic Network with Kinetic Parameters

    Adadi R., Volkmer B., Milo R., Heinemann M. & Shlomi T. (2012)
  • A Genome-Wide Analysis of Promoter-Mediated Phenotypic Noise in Escherichia coli

    Silander O. K., Nikolic N., Zaslaver A., Bren A., Kikoin I., Alon U. & Ackermann M. (2012)