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All Publications

  • Examining the NEUROG2 lineage and associated gene expression in human cortical organoids

    Authors: Vasan L., Chinchalongporn V., Saleh F., Zinyk D., Ke C., Suresh H., Ghazale H., Belfiore L., Touahri Y., Oproescu A. M., Patel S., Rozak M., Amemiya Y., Han S., Moffat A., Black S. E., McLaurin J. A., Near J., Seth A., Goubran M., Reiner O., Gillis J., Wang C., Okawa S. & Schuurmans C. (2025), Development (Cambridge). 152, 2, dev202703

  • Sengers syndrome caused by biallelic TIMM29 variants and RNAi silencing in Drosophila orthologue recapitulates the human phenotype

    Authors: Shalata A., Saada A., Mahroum M., Hadid Y., Furman C., Shalata Z. E., Desnick R. J., Lorber A., Khoury A., Higazi A., Shaag A., Barash V., Spiegel R., Vlodavsky E., Rustin P., Pietrokovski S., Manov I., Gieger D., Tal G., Salzberg A. & Mandel H. (2025), Human Genomics. 19, 21

  • Piezo2 in sensory neurons regulates systemic and adipose tissue metabolism

    Authors: Passini F. S., Bornstein B., Rubin S., Kuperman Y., Krief S., Masschelein E., Mehlman T., Brandis A., Addadi Y., Shalom S. H. O., Richter E. A., Yardeni T., Tirosh A., De Bock K. & Zelzer E. (2025), Cell Metabolism.

  • A framework for neural organoids, assembloids and transplantation studies

    Authors: Pașca S. P., Arlotta P., Bateup H. S., Camp J. G., Cappello S., Gage F. H., Knoblich J. A., Kriegstein A. R., Lancaster M. A., Ming G. L., Novarino G., Okano H., Parmar M., Park I. H., Reiner O., Song H., Studer L., Takahashi J., Temple S., Testa G., Treutlein B., Vaccarino F. M., Vanderhaeghen P. & Young-Pearse T. (2025), Nature. 639, 8054, p. 315-320

  • Limited column formation in the embryonic growth plate implies divergent growth mechanisms during pre- and postnatal bone development

    Authors: Rubin S., Agrawal A., Seewald A., Lian M. J., Gottdenker O., Villoutreix P., Baule A., Stern T. & Zelzer E. (2024), eLife. 13

  • Putting together pieces of the LIN28A pathway puzzle

    Authors: Yilmaz A., Gurhan G. & Hanna J. H. (2024),

  • Temporal BMP4 effects on mouse embryonic and extraembryonic development

    Authors: Hadas R., Rubinstein H., Mittnenzweig M., Mayshar Y., Ben-Yair R., Cheng S., Aguilera-Castrejon A., Reines N., Orenbuch A., Lifshitz A., Chen D., Elowitz M. B., Zernicka-Goetz M., Hanna J. H., Tanay A. & Stelzer Y. (2024), Nature. 634, 8034, p. 652-661

  • SNX10 regulates osteoclastogenic cell fusion and osteoclast size in mice

    Authors: Barnea-Zohar M., Stein M., Reuven N., Winograd-Katz S., Lee S., Addadi Y., Arman E., Tuckermann J., Geiger B. & Elson A. (2024), Journal of Bone and Mineral Research. 39, 10, p. 1503-1517

  • Flagellar stator genes control a trophic shift from obligate to facultative predation and biofilm formation in a bacterial predator

    Authors: Mookherjee A., Mitra M., Sason G., Jose P. A., Martinenko M., Pietrokovski S. & Jurkevitch E. (2024), mBio. 15, 8, e0071524

  • Egg multivesicular bodies elicit an LC3-associated phagocytosis-like pathway to degrade paternal mitochondria after fertilization

    Authors: Ben-Hur S., Sernik S., Afar S., Kolpakova A., Politi Y., Gal L., Florentin A., Golani O., Sivan E., Dezorella N., Morgenstern D., Pietrokovski S., Schejter E., Yacobi-Sharon K. & Arama E. (2024), Nature Communications. 15, 5715

  • Criteria for the standardization of stem-cell-based embryo models

    Authors: Martinez Arias A., Rivron N., Moris N., Tam P., Alev C., Fu J., Hadjantonakis A. K., Hanna J. H., Minchiotti G., Pourquie O., Sheng G., Solnica Krezel L., Veenvliet J. V. & Warmflash A. (2024),

  • Expanding and Enriching the LncRNA GeneDisease Landscape Using the GeneCaRNA Database

    Authors: Aggarwal S., Rosenblum C., Gould M., Ziman S., Barshir R., Zelig O., Guan-Golan Y., Iny-Stein T., Safran M., Pietrokovski S. & Lancet D. (2024), Biomedicines. 12, 6, 1305

  • Loss-of-function cancer-linked mutations in the EIF4G2 non-canonical translation initiation factor

    Authors: Meril S., Bahlsen M., Eisenstein M., Savidor A., Levin Y., Bialik S., Pietrokovski S. & Kimchi A. (2024), Life Science Alliance. 7, 3, e202302338

  • Runx3, Brn3a and Isl1 interplay orchestrates the transcriptional program in the early stages of proprioceptive neuron development

    Authors: Orlovsky K., Appel E., Hantisteanu S., Olender T., Lotem J., Levanon D. & Groner Y. (2024), PLoS Genetics. 20, 12, e1011401

  • Passive shaping of intra- and intercellular m6A dynamics via mRNA metabolism

    Authors: Dierks D., Shachar R., Nir R., Garcia-Campos M. A., Uzonyi A., Toth U., Rossmanith W., Lasman L., Slobodin B., Hanna J. H., Antebi Y., Scherz-Shouval R. & Schwartz S. (2024), eLife. 13, RP100448

  • Depletion of Mettl3 in cholinergic neurons causes adult-onset neuromuscular degeneration

    Authors: Dermentzaki G., Furlan M., Tanaka I., Leonardi T., Rinchetti P., Passos P. M., Bastos A., Ayala Y. M., Hanna J. H., Przedborski S., Bonanomi D., Pelizzola M. & Lotti F. (2024), Cell Reports. 43, 4, 113999

  • Guided-attention and gated-aggregation network for medical image segmentation

    Authors: Fiaz M., Noman M., Cholakkal H., Anwer R. M., Hanna J. & Khan F. S. (2024), Pattern Recognition. 156, 110812

  • Multigenerational inheritance drives symbiotic interactions of the bacterium Bacillus subtilis with its plant host

    Authors: Gilhar O., Ben-Navi L. R., Olender T., Aharoni A., Friedman J. & Kolodkin-Gal I. (2024), Microbiological Research. 286, 127814

  • A role for TGFβ signaling in Gli1+ tendon and enthesis cells

    Authors: Song L., Golman M., Abraham A. C., Zelzer E. & Thomopoulos S. (2024), FASEB Journal. 38, 6, e23568

  • Osteoclast Methods in Protein Phosphatase Research

    Authors: Reuven N., Barnea-Zohar M. & Elson A. (2024), Protein Tyrosine Phosphatases. Thevenin D. & Muller J. P. (eds.). p. 57-79

  • Modeling primary microcephaly with human brain organoids reveals fundamental roles of CIT kinase activity

    Authors: Pallavicini G., Moccia A., Iegiani G., Parolisi R., Peirent E. R., Berto G. E., Lorenzati M., Tshuva R. Y., Ferraro A., Balzac F., Turco E., Salvi S. U., Myklebust H. F., Wang S., Eisenberg J., Chitale M., Girgla N. S., Boda E., Reiner O., Buffo A., Di Cunto F. & Bielas S. L. (2024), Journal of Clinical Investigation. 134, 21, e175435

  • A patterned human neural tube model using microfluidic gradients

    Authors: Xue X., Kim Y. S., Ponce-Arias A. I., OLaughlin R., Yan R. Z., Kobayashi N., Tshuva R. Y., Tsai Y. H., Sun S., Zheng Y., Liu Y., Wong F. C., Surani A., Spence J. R., Song H., Ming G. L., Reiner O. & Fu J. (2024), Nature. 628, 8007, p. 391-399

  • Metabolic inputs in the probiotic bacterium Lacticaseibacillus rhamnosus contribute to cell-wall remodeling and increased fitness

    Authors: Suissa R., Olender T., Malitsky S., Golani O., Turjeman S., Koren O., Meijler M. M. & Kolodkin-Gal I. (2023), npj Biofilms and Microbiomes. 9, 1, 71

  • A pathogenic variant in the uncharacterized RNF212B gene results in severe aneuploidy male infertility and repeated IVF failure

    Authors: Gershoni M., Braun T., Hauser R., Barda S., Lehavi O., Malcov M., Frumkin T., Kalma Y., Pietrokovski S., Arama E. & Kleiman S. E. (2023), HGG advances. 4, 3, 100189

  • Structural and biochemical analysis of a novel atypically split intein reveals a conserved histidine specific to cysteine-less inteins

    Authors: Pasch T., Schröder A., Kattelmann S., Eisenstein M., Pietrokovski S., Kümmel D. & Mootz H. D. (2023), Chemical Science. 14, 19, p. 5204-5213

  • Complete human day 14 post-implantation embryo models from naive ES cells

    Authors: Oldak B., Wildschutz E., Bondarenko V., Comar M., Zhao C., Aguilera-Castrejon A., Tarazi S., Viukov S., Pham T. X. A., Ashouokhi S., Lokshtanov D., Roncato F., Ariel E., Rose M., Livnat N., Shani T., Joubran C., Cohen R., Addadi Y., Chemla M., Kedmi M., Keren-Shaul H., Pasque V., Petropoulos S., Lanner F., Novershtern N. & Hanna J. H. (2023), Nature. 622, 7983, p. 562-573

  • Induced epigenetic changes memorized across generations in mice

    Authors: Cheng S., Mayshar Y. & Stelzer Y. (2023),

  • Single-nucleus multiomic mapping of m6A methylomes and transcriptomes in native populations of cells with sn-m6A-CT

    Authors: Hamashima K., Wong K. W., Sam T. W., Teo J. H. J., Taneja R., Le M. T., Li Q. J., Hanna J. H., Li H. & Loh Y. H. (2023), Molecular Cell. 83, 17, p. 3205-3216.e5

  • The mechanosensitive ion channel ASIC2 mediates both proprioceptive sensing and spinal alignment

    Authors: Bornstein B., Watkins B., Passini F. S., Blecher R., Assaraf E., Sui X. M., Brumfeld V., Tsoory M., Kröger S. & Zelzer E. (2023), Experimental Physiology. 109, 1, p. 135-147

  • LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways

    Authors: Kshirsagar A., Doroshev S. M., Gorelik A., Olender T., Sapir T., Tsuboi D., Rosenhek-Goldian I., Malitsky S., Itkin M., Argoetti A., Mandel-Gutfreund Y., Cohen S. R., Hanna J. H., Ulitsky I., Kaibuchi K. & Reiner O. (2023), Nature Communications. 14, 1, 3293

  • Molecular characterization of the intact mouse muscle spindle using a multi-omics approach

    Authors: Bornstein B., Heinemann-Yerushalmi L., Krief S., Adler R., Dassa B., Leshkowitz D., Kim M., Bewick G., Banks R. W. & Zelzer E. (2023), eLife. 12, e81843

  • BASP1 down-regulates RANKL-induced osteoclastogenesis

    Authors: Anuj A., Reuven N., Roberts S. G. & Elson A. (2023), Experimental Cell Research. 431, 1, 113758

  • Time-aligned hourglass gastrulation models in rabbit and mouse

    Authors: Mayshar Y., Raz O., Cheng S., Ben-Yair R., Hadas R., Reines N., Mittnenzweig M., Ben-Kiki O., Lifshitz A., Tanay A. & Stelzer Y. (2023), Cell. 186, 12, p. 2610-2627.e18

  • HNRNPU's multi-tasking is essential for proper cortical development

    Authors: Sapir T. & Reiner O. (2023), BioEssays. 45, 9, 2300039

  • 3D Mitochondria Instance Segmentation with Spatio-Temporal Transformers

    Authors: Thawakar O., Anwer R. M., Laaksonen J., Reiner O., Shah M. & Khan F. S. (2023), Medical Image Computing and Computer Assisted Intervention MICCAI 2023 - 26th International Conference, Proceedings. p. 613-623

  • Instruction of epigenetic states from DNA sequences

    Authors: Stelzer Y. (2023), Nature reviews. Molecular cell biology. 24, 3, p. 164

  • Improving 3D Medical Image Segmentation at Boundary Regions using Local Self-attention and Global Volume Mixing

    Authors: Abdul Kareem D. N., Fiaz M., Novershtern N., Hanna J. & Cholakkal H. (2023), IEEE Transactions on Artificial Intelligence. 5, 6, p. 1-12

  • A single-cell census of mouse limb development identifies complex spatiotemporal dynamics of skeleton formation

    Authors: Markman S., Zada M., David E., Giladi A., Amit I. & Zelzer E. (2023), Developmental Cell. 58, 7, p. 565-581.e4

  • m6A RNA modification regulates innate lymphoid cell responses in a lineage-specific manner

    Authors: Zhang Y., Zhang W., Zhao J., Ito T., Jin J., Aparicio A. O., Zhou J., Guichard V., Fang Y., Que J., Urban J. F., Hanna J. H., Ghosh S., Wu X., Ding L., Basu U. & Huang Y. (2023), Nature Immunology. 24, 8, p. 1256-1264

  • The Emerging Roles of LIS1 Biomechanics in Cellular and Cortical Homeostasis

    Authors: Kshirsagar A. & Reiner O. (2023), Neocortical Neurogenesis in Development and Evolution. Huttner W. (eds.). p. 365-396

  • Editorial: Pluripotent stem cell engineered 3D structures for disease modeling and tissue repairing

    Authors: Qiang L., Lane M. A., Doege C. A., Reiner O. & Fischer I. (2023), Frontiers in Cellular Neuroscience. 17, 1146143

  • Histone exchange sensors reveal variant specific dynamics in mouse embryonic stem cells

    Authors: Dunjic M., Jonas F., Yaakov G., More R., Mayshar Y., Rais Y., Barkai N. & Stelzer Y. (2023), Nature Communications. 14, 1, 3791

  • Evidence of shared transcriptomic dysregulation of HNRNPU-related disorder between human organoids and embryonic mice

    Authors: Ressler A. K., Sampaio G. L., Dugger S. A., Sapir T., Krizay D., Boland M. J., Reiner O. & Goldstein D. B. (2023), iScience. 26, 1, 105797

  • Calcium carbonate mineralization is essential for biofilm formation and lung colonization

    Authors: Cohen-Cymberknoh M., Kolodkin-Gal D., Keren-Paz A., Peretz S., Brumfeld V., Kapishnikov S., Suissa R., Shteinberg M., McLeod D., Maan H., Patrauchan M., Zamir G., Kerem E. & Kolodkin-Gal I. (2022), iScience. 25, 5, 104234

  • Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development

    Authors: Lau K., Rubinstein H., Gantner C., Hadas R., Amadei G., Stelzer Y. & Zernicka-Goetz M. (2022), Cell Stem Cell. 29, 10, p. 1445-1458

  • YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation

    Authors: Grenov A., Hezroni H., Lasman L., Hanna J. H. & Shulman Z. (2022), Cell Reports. 39, 5, 110778

  • Imaging flow cytometry reveals a dual role for exopolysaccharides in biofilms: To promote self-adhesion while repelling non-self-community members

    Authors: Maan H., Povolotsky T. L., Porat Z., Itkin M., Malitsky S. & Kolodkin-Gal I. (2022), Computational and Structural Biotechnology Journal. 20, p. 15-25

  • Resolving the conflict between antibiotic production and rapid growth by recognition of peptidoglycan of susceptible competitors

    Authors: Maan H., Itkin M., Malitsky S., Friedman J. & Kolodkin-Gal I. (2022), Nature Communications. 13, 1, 431

  • Molecular genetics for probiotic engineering: dissecting lactic acid bacteria

    Authors: Suissa R., Oved R., Jankelowitz G., Turjeman S., Koren O. & Kolodkin-Gal I. (2022), Trends in microbiology (Regular ed.). 30, 3, p. 293-306

  • A mineralizing pool of Gli1-expressing progenitors builds the tendon enthesis and demonstrates therapeutic potential

    Authors: Fang F., Xiao Y., Zelzer E., Leong K. W. & Thomopoulos S. (2022), Cell Stem Cell. 29, 12, p. 1669-1684.e6

  • Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate

    Authors: Parichha A., Suresh V., Chatterjee M., Kshirsagar A., Ben-Reuven L., Olender T., Taketo M. M., Radosevic V., Bobic-Rasonja M., Trnski S., Holtzman M. J., Jovanov-Milosevic N., Reiner O. & Tole S. (2022), Nature Communications. 13, 1, 633

  • The roles of intracellular and extracellular calcium in Bacillus subtilis biofilms

    Authors: Keren-Paz A., Maan H., Karunker I., Olender T., Kapishnikov S., Dersch S., Kartvelishvily E., Wolf S. G., Gal A., Graumann P. L. & Kolodkin-Gal I. (2022), iScience. 25, 6, 104308

  • Stabilization of hESCs in two distinct substates along the continuum of pluripotency

    Authors: Dekel C., Morey R., Hanna J., Laurent L. C., Ben-Yosef D. & Amir H. (2022), iScience. 25, 12, 105469

  • The Products of Probiotic Bacteria Effectively Treat Persistent Enterococcus faecalis Biofilms

    Authors: Safadi S., Maan H., Kolodkin-Gal I., Tsesis I. & Rosen E. (2022), Pharmaceutics. 14, 4, 751

  • Abnormalities in Cortical GABAergic Interneurons of the Primary Motor Cortex Caused by Lis1 (Pafah1b1) Mutation Produce a Non-drastic Functional Phenotype

    Authors: Domínguez-Sala E., Valdés-Sánchez L., Canals S., Reiner O., Pombero A., García-López R., Estirado A., Pastor D., Geijo-Barrientos E. & Martínez S. (2022), Frontiers in Cell and Developmental Biology. 10, 769853

  • The Future of Parkinson's Disease Research: A New Paradigm of Human Specific Investigation Is Necessary and Possible

    Authors: Cassotta M., Geerts H., Harbom L., Outeiro T. F., Pediaditakis I., Reiner O., Schildknecht S., Schwamborn J. C., Bailey J., Herrmann K. & Hogberg H. T. (2022), ALTEX, alternatives to animal experimentation. 39, 4, p. 694-709

  • Human primed and naïve PSCs are both able to differentiate into trophoblast stem cells

    Authors: Viukov S., Shani T., Bayerl J., Aguilera-Castrejon A., Oldak B., Sheban D., Tarazi S., Stelzer Y., Hanna J. H. & Novershtern N. (2022), Stem Cell Reports. 17, 11, p. 2484-2500

  • The origins and formation of bone-resorbing osteoclasts

    Authors: Elson A., Anuj A., Barnea-Zohar M. & Reuven N. (2022), Bone (New York, N.Y.). 164, 116538

  • Embryo model completes gastrulation to neurulation and organogenesis

    Authors: Amadei G., Handford C. E., Qiu C., De Jonghe J., Greenfeld H., Tran M., Martin B. K., Chen D., Aguilera-Castrejon A., Hanna J. H., Elowitz M., Hollfelder F., Shendure J., Glover D. M. & Zernicka-Goetz M. (2022), Nature (London). 610, 7930, p. 143-153

  • Context-dependent differences in the functional responses of Lactobacillaceae strains to fermentable sugars

    Authors: Suissa R., Oved R., Maan H., Hadad U., Gilhar O., Meijler M. M., Koren O. & Kolodkin-Gal I. (2022), Frontiers in Microbiology. 13, 949932

  • A nomenclature consensus for nervous system organoids and assembloids

    Authors: Pasca S. P., Arlotta P., Bateup H. S., Camp J. G., Cappello S., Gage F. H., Knoblich J. A., Kriegstein A. R., Lancaster M. A., Ming G., Muotri A. R., Park I., Reiner O., Song H., Studer L., Temple S., Testa G., Treutlein B. & Vaccarino F. M. (2022), Nature. 609, 7929, p. 907-910

  • Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs

    Authors: Tarazi S., Aguilera Castrejon A., Joubran C., Ghanem N., Ashouokhi S., Roncato F., Wildschutz E., Haddad M., Oldak B., Gomez-Cesar E., Livnat N., Viukov S., Lukshtanov D., Naveh Tassa S., Rose M., Issaq - Hanna S., Raanan C., Brenner O. J., Kedmi M., Keren-Shaul H., Lapidot T., Maza I., Novershtern N. & Hanna J. (. (2022), Cell. 185, 18, p. 3290-3306.e25

  • SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity

    Authors: Sheban D., Shani T., Maor R., Aguilera-Castrejon A., Mor N., Oldak B., Shmueli M. D., Eisenberg-Lerner A., Bayerl J., Hebert J., Viukov S., Chen G., Kacen A., Krupalnik V., Chugaeva V., Tarazi S., Rodríguez-delaRosa A., Zerbib M., Ulman A., Masarwi S., Kupervaser M., Levin Y., Shema E., David Y., Novershtern N., Hanna J. H. & Merbl Y. (2022), Molecular Cell. 82, 1, p. 106-122.e9

  • Recent insights into mammalian natural and synthetic ex utero embryogenesis

    Authors: Oldak B., Aguilera-Castrejon A. & Hanna J. H. (2022), Current opinion in genetics & development. 77, 101988

  • Neonatal Enthesis Healing Involves Noninflammatory Acellular Scar Formation through Extracellular Matrix Secretion by Resident Cells

    Authors: Vinestock R. C., Felsenthal N., Assaraf E., Katz E., Rubin S., Heinemann-Yerushalmi L., Krief S., Dezorella N., Levin-Zaidman S., Tsoory M., Thomopoulos S. & Zelzer E. (2022), American Journal of Pathology. 192, 8, p. 1122-1135

  • Brain Organization and Human Diseases

    Authors: Sapir T., Sela-Donenfeld D., Karlinski M. & Reiner O. (2022), Cells (Basel, Switzerland). 11, 10, 1642

  • Pls1 Is a Peroxisomal Matrix Protein with a Role in Regulating Lysine Biosynthesis

    Authors: David Y., Castro I. G., Yifrach E., Bibi C., Katawi E., Har-Shai D. Y., Brodsky S., Barkai N., Ravid T., Eisenstein M., Pietrokovski S., Schuldiner M. & Zalckvar E. (2022), Cells. 11, 9, 1426

  • The intrinsic and extrinsic effects of TET proteins during gastrulation

    Authors: Cheng S., Mittnenzweig M., Mayshar Y., Lifshitz A., Dunjic M., Rais Y., Ben-Yair R., Gehrs S., Chomsky E., Mukamel Z., Rubinstein H., Schlereth K., Reines N., Orenbuch A., Tanay A. & Stelzer Y. (2022), Cell. 185, 17, p. 3169-3185.e20

  • Balanced gene dosage control rather than parental origin underpins genomic imprinting

    Authors: Weinberg-Shukron A., Ben Yair R., Takahashi N., Dunjic M., Shtrikman A., Edwards C. A., Ferguson-Smith A. & Stelzer Y. (2022), Nature Communications. 13, 4391

  • Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex

    Authors: Sapir T., Kshirsagar A., Gorelik A., Olender T., Porat Z., Scheffer I. E., Goldstein D. B., Devinsky O. & Reiner O. (2022), Nature Communications. 13, 1, 4209

  • A single-embryo, single-cell time-resolved model for mouse gastrulation

    Authors: Mittnenzweig M., Mayshar Y., Cheng S., Ben Yair R., Hadas R., Rais Y., Chomsky E., Reines N., Uzonyi A., Lumerman L., Lifshitz A., Mukamel Z., Orenbuch A. H., Tanay A. & Stelzer Y. (2021), Cell. 184, 11, p. 2825-2842.e22

  • Editorial: Complement in the Development and Regeneration of the Nervous System

    Authors: Brennan F. H., Coulthard L. G., Alawieh A. M., Reiner O. & Pekna M. (2021), Frontiers in Immunology. 12, 694810

  • Deciphering the principles of the RNA editing code via large-scale systematic probing

    Authors: Uzonyi A., Nir R., Shliefer O., Stern-Ginossar N., Antebi Y., Stelzer Y., Levanon E. Y. & Schwartz S. (2021), Molecular Cell. 81, 11, p. 2374-2387.e3

  • Application of 3D MAPs pipeline identifies the morphological sequence chondrocytes undergo and the regulatory role of GDF5 in this process

    Authors: Rubin S., Agrawal A., Stegmaier J., Krief S., Felsenthal N., Svorai J., Addadi Y., Villoutreix P., Stern T. & Zelzer E. (2021), Nature Communications. 12, 1, p. 1-16, 5363

  • Multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution

    Authors: Dierks D., Garcia-Campos M. A., Uzonyi A., Safra M., Edelheit S., Rossi A., Sideri T., Varier R. A., Brandis A., Stelzer Y., van Werven F., Scherz-Shouval R. & Schwartz S. (2021), Nature Methods. 18, 9, p. 1060-1067

  • Bacillus subtilis Colonization of Arabidopsis thaliana Roots Induces Multiple Biosynthetic Clusters for Antibiotic Production

    Authors: Maan H., Gilhar O., Porat Z. & Kolodkin-Gal I. (2021), Frontiers in Cellular and Infection Microbiology. 11, 722778

  • Editorial: Developmental Biology and Regulation of Osteoclasts

    Authors: Gabet Y., Neumann D., Levaot N., Elson A. & Sims N. A. (2021), Frontiers in Cell and Developmental Biology. 9, 769320

  • Voices of biotech research

    Authors: Annabi N., Baker M., Boettiger A., Chakraborty D., Chen Y., Corbett K. S., Correia B., Dahlman J., de Oliveira T., Ertuerk A., Yanik M. F., Henaff E., Huch M., Iliev I. D., Jacobs T., Junca H., Keung A., Kolodkin-Gal I., Krishnaswamy S., Lancaster M., Macosko E., Martínez-Núñez M. A., Miura K., Molloy J., Cruz A. O., Platt R. J., Posey, Jr A. D., Shao H., Simunovic M., Slavov N., Takebe T., Vandenberghe L. H., Varshney R. K. & Wang J. (2021),

  • Principles of signaling pathway modulation for enhancing human naive pluripotency induction

    Authors: Bayerl J., Ayyash M., Shani T., Manor Y. S., Gafni O., Massarwa R., Kalma Y., Aguilera-Castrejon A., Zerbib M., Amir H., Sheban D., Geula S., Mor N., Weinberger L., Naveh Tassa S., Krupalnik V., Oldak B., Livnat N., Tarazi S., Wildschutz E., Tawil S., Ashouokhi S., Lasman L., Rotter V., Hanna S., Ben-Yosef D., Novershtern N., Viukov S. & Hanna J. H. (2021), Cell Stem Cell. 28, 9, p. 1549-1565.e12

  • Role of OSCAR Signaling in Osteoclastogenesis and Bone Disease

    Authors: Nedeva I. R., Vitale M., Elson A., Hoyland J. A. & Bella J. (2021), Frontiers in Cell and Developmental Biology. 9, 641162

  • Immunofluorescent Staining of Adult Murine Paraffin-Embedded Skeletal Tissue

    Authors: Felsenthal N. & Zelzer E. (2021), Skeletal Development and Repair. Hilton M. J. (eds.). p. 337-344

  • More than movement: the proprioceptive system as a new regulator of musculoskeletal biology

    Authors: Bornstein B., Konstantin N., Alessandro C., Tresch M. C. & Zelzer E. (2021), Current Opinion in Physiology. 20, p. 77-89

  • An SNX10-dependent mechanism downregulates fusion between mature osteoclasts

    Authors: Barnea Zohar M., Winograd-Katz S., Shalev M., Arman E., Reuven N., Roth L., Golani O., Stein M., Thalji F., Kanaan M., Tuckermann J., Geiger B. & Elson A. (2021), Journal of Cell Science. 134, 9, jcs254979

  • PTPRJ promotes osteoclast maturation and activity by inhibiting Cbl-mediated ubiquitination of NFATc1 in late osteoclastogenesis

    Authors: Shalev M., Arman E., Stein M., Cohen-Sharir Y., Brumfeld V., Kapishnikov S., Royal I., Tuckermann J. & Elson A. (2021), FEBS Journal. 288, 15, p. 4702-4723

  • Runx1 and Runx3 drive progenitor to T-lineage transcriptome conversion in mouse T cell commitment via dynamic genomic site switching

    Authors: Shin B., Hosokawa H., Romero-Wolf M., Zhou W., Masuhara K., Tobin V. R., Levanon D., Groner Y. & Rothenberg E. V. (2021), Proceedings of the National Academy of Sciences of the United States of America. 118, 4, 2019655118

  • Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis

    Authors: Aguilera-Castrejon A., Shani T., Ghanem N., Itzkovich C., Slomovich S., Tarazi S., Bayerl J., Chugaeva V., Ayyash M., Ashouokhi S., Sheban D., Livnat N., Lasman L., Viukov S., Zerbib M., Addadi Y., Rais Y., Cheng S., Keren-Shaul H., Stelzer Y., Shlomo R., Massarwa R., Novershtern N. & Hanna J. H. (2021), Nature (London). 593, 7857, p. 119-124

  • Sorting Nexin 10 as a Key Regulator of Membrane Trafficking in Bone-Resorbing Osteoclasts: Lessons Learned From Osteopetrosis

    Authors: Elson A., Stein M., Rabie G., Barnea-Zohar M., Winograd-Katz S., Reuven N., Shalev M., Sekeres J., Kanaan M., Tuckermann J. & Geiger B. (2021), Frontiers in Cell and Developmental Biology. 9, 671210

  • Bi-fated tendon-to-bone attachment cells are regulated by shared enhancers and KLF transcription factors

    Authors: Kult S., Olender T., Osterwalder M., Markman S., Leshkowitz D., Krief S., Blecher-Gonen R., Ben-Moshe S., Farack L., Keren-Shaul H., Salame T. M., Capellini T. D., Itzkovitz S., Amit I., Visel A. & Zelzer E. (2021), eLife. 10, p. 1-29, 55361

  • Production and analysis of human primordial germ celllike cells

    Authors: Mitsunaga S., Shioda K., Hanna J. H., Isselbacher K. J. & Shioda T. (2021), Testicular Germ Cell Tumors: Methods and Protocols. Vol. 2195. p. 125-145

  • Modeling human neuronal migration deficits in 3D

    Authors: Reiner O., Parichha A. & Sapir T. (2021), Current Opinion in Neurobiology. 66, p. 30-36

  • Weaponizing volatiles to inhibit competitor biofilms from a distance

    Authors: Hou Q., Keren-Paz A., Korenblum E., Oved R., Malitsky S. & Kolodkin-Gal I. (2021), npj Biofilms and Microbiomes. 7, 1, 2

  • BCKDK regulates the TCA cycle through PDC in the absence of PDK family during embryonic development

    Authors: Heinemann-Yerushalmi L., Bentovim L., Felsenthal N., Vinestock R. C., Michaeli N., Krief S., Silberman A., Cohen M., Ben-Dor S., Brenner O., Haffner-Krausz R., Itkin M., Malitsky S., Erez A. & Zelzer E. (2021), Developmental Cell. 56, 8, p. 1182-1194.e6

  • The germinal center reaction depends on RNA methylation and divergent functions of specific methyl readers

    Authors: Grenov A. C., Moss L., Edelheit S., Cordiner R., Schmiedel D., Biram A., Hanna J. H., Jensen T. H., Schwartz S. & Shulman Z. (2021), Journal of Experimental Medicine. 218, 10, e20210360

  • Use of iPSC-derived brain organoids to study human brain evolution

    Authors: Reiner O., Sapir T. & Parichha A. (2021), Recent Advances in iPSC Technology. Vol. 5. p. 157-177

  • Control of Foxp3 induction and maintenance by sequential histone acetylation and DNA demethylation

    Authors: Li J., Xu B., He M., Zong X., Cunningham T., Sha C., Fan Y., Cross R., Hanna J. H. & Feng Y. (2021), Cell reports (Cambridge). 37, 11, 110124

  • Neuronal deletion of Wwox, associated with WOREE syndrome, causes epilepsy and myelin defects

    Authors: Repudi S., Steinberg D. J., Elazar N., Breton V. L., Aquilino M. S., Saleem A., Abu-Swai S., Vainshtein A., Eshed-Eisenbach Y., Vijayaragavan B., Behar O., Hanna J. J., Peles E., Carlen P. L. & Aqeilan R. I. (2021), Brain. 144, 10, p. 3061-3077

  • Ex Utero Culture of Mouse Embryos from Pregastrulation to Advanced Organogenesis

    Authors: Aguilera-Castrejon A. & Hanna J. H. (2021), Nature. 593, 176, p. 119-124, e63160

  • Emerging Roles of Functional Bacterial Amyloids in Gene Regulation, Toxicity, and Immunomodulation

    Authors: Salinas N., Povolotsky T. L., Landau M. & Kolodkin-Gal I. (2021), Microbiology and molecular biology reviews : MMBR. 85, 1, 00062-20

  • Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis

    Authors: Marmor-Kollet H., Siany A., Kedersha N., Knafo N., Rivkin N., Danino Y. M., Moens T. G., Olender T., Sheban D., Cohen N., Dadosh T., Addadi Y., Ravid R., Eitan C., Toth Cohen B., Hofmann S., Riggs C. L., Advani V. M., Higginbottom A., Cooper-Knock J., Hanna J. H., Merbl Y., Van Den Bosch L., Anderson P., Ivanov P., Geiger T. & Hornstein E. (2020), Molecular Cell. 80, 5, p. 876-891

  • Biochemical and Structural Characterization of an Unusual and Naturally Split Class 3 Intein

    Authors: Hoffmann S., Terhorst T. M. E., Singh R. K., Kuemmel D., Pietrokovski S. & Mootz H. D. (2020), ChemBioChem. 2, p. 364-373

  • Nucleokinesis

    Authors: Reiner O. & Karzbrun E. (2020), Cellular Migration and Formation of Axons and Dendrites. p. 305-322

  • Using multi-organ culture systems to study Parkinsons disease

    Authors: Reiner O., Sapir T. & Parichha A. (2020), Molecular Psychiatry. 26, 3, p. 725-735

  • Metabolic Microenvironments Drive Microbial Differentiation and Antibiotic Resistance

    Authors: Povolotsky T. L., Keren-Paz A. & Kolodkin-Gal I. (2020),

  • International consensus recommendations on the diagnostic work-up for malformations of cortical development

    Authors: Oegema R., Barakat T. S., Wilke M., Stouffs K., Amrom D., Aronica E., Bahi-Buisson N., Conti V., Fry A. E., Geis T., Gomez Andres D., Parrini E., Pogledic I., Said E., Soler D., Valor L. M., Zaki M. S., Mirzaa G., Dobyns W. B., Reiner O., Guerrini R., Pilz D. T., Hehr U., Leventer R. J., Jansen A. C., Mancini G. M. S. & Di Donato N. (2020), Nature Reviews Neurology. 16, 11, p. 618-635

  • Characterization of Endoplasmic Reticulum (ER) in Human Pluripotent Stem Cells Revealed Increased Susceptibility to Cell Death upon ER Stress

    Authors: Ha T. W., Jeong J. H., Shin H., Kim H. K., Im J. S., Song B. H., Hanna J., Oh J. S., Woo D., Han J. & Lee M. R. (2020), Cells. 9, 5, 1078

  • The extracellular matrix protein TasA is a developmental cue that maintains a motile subpopulation within Bacillus subtilis biofilms

    Authors: Steinberg N., Keren-Paz A., Hou Q., Doron S., Yanuka-Golub K., Olender T., Hadar R., Rosenberg G., Jain R., Camara-Almiron J., Romero D., van Teeffelen S. & Kolodkin-Gal I. (2020), Science Signaling. 13, 632, 8905

  • Cell type-specific actions of Bcl11b in early T-lineage and group 2 innate lymphoid cells

    Authors: Hosokawa H., Romero-Wolf M., Yang Q., Motomura Y., Levanon D., Groner Y., Moro K., Tanaka T. & Rothenberg E. (2020), Journal of Experimental Medicine. 217, 1, 20190972

  • Context-dependent functional compensation between Ythdf m6A reader proteins

    Authors: Lasman L., Krupalnik V., Viukov S., Mor N., Aguilera-Castrejon A., Schneir D., Bayerl J., Mizrahi O., Peles S., Tawil S., Sathe S., Nachshon A., Shani T., Zerbib M., Kilimnik I., Aigner S., Shankar A., Mueller J. R., Schwartz S., Stern-Ginossar N., Yeo G. W., Geula S., Novershtern N. & Hanna J. H. (2020), Genes and Development. 34, 19-20, p. 1373-1391

  • Brain organoids as a model system for human neurodevelopment in health and disease

    Authors: Reiner O. & Karzbrun E. (2020), Patterning and Cell Type Specification in the Developing CNS and PNS. p. 205-221

  • Role of m(6)A in Embryonic Stem Cell Differentiation and in Gametogenesis

    Authors: Lasman L., Hanna J. H. & Novershtern N. (2020), Epigenomes. 4, 1, 5

  • Harvesting the complex pathways of antibiotic production and resistance of soil bacilli for optimizing plant microbiome

    Authors: Hou Q. & Kolodkin-Gal I. (2020), FEMS Microbiology Ecology. 96, 9, 142

  • LifeTime and improving European healthcare through cell-based interceptive medicine

    Authors: Rajewsky N., Almouzni G., Amit I., Tanay A. & Reiner O. (2020), Nature. 587, 7834, p. 377-386

  • Dasatinib response in acute myeloid leukemia is correlated with FLT3/ITD, PTPN11 mutations and a unique gene expression signature

    Authors: Tavor S., Shalit T., Chapal Ilani N., Moskovitz Y., Livnat N., Groner Y., Barr H., Minden M. D., Plotnikov A., Deininger M. W., Kaushansky N. & Shlush L. I. (2020), Haematologica. 105, 12, p. 2795-2804

  • Runx3 prevents spontaneous colitis by directing the differentiation of anti-inflammatory mononuclear phagocytes

    Authors: Hantisteanu S., Dicken Y., Negreanu V., Goldenberg D., Brenner O., Leshkowitz D., Lotem J., Levanon D. & Groner Y. (2020), PLoS ONE. 15, 5, e0233044

  • Complement System in Brain Architecture and Neurodevelopmental Disorders

    Authors: Magdalon J., Mansur F., Teles e Silva A. L., de Goes V. A., Reiner O. & Sertie A. L. (2020), Frontiers in Neuroscience. 14, 23

  • Generation of human endothelium in pig embryos deficient in ETV2

    Authors: Das S., Koyano-Nakagawa N., Gafni O., Maeng G., Singh B. N., Rasmussen T., Pan X., Choi K., Mickelson D., Gong W., Pota P., Weaver C. V., Kren S., Hanna J. H., Yannopoulos D., Garry M. G. & Garry D. J. (2020), Nature Biotechnology. 38, 3, p. 297-302

  • Toward spatial identities in human brain organoids-on-chip induced by morphogen-soaked beads

    Authors: Ben-Reuven L. & Reiner O. (2020), Bioengineering. 7, 4, p. 1-17, 164

  • beta-Catenin safeguards the ground state of mouse pluripotency by strengthening the robustness of the transcriptional apparatus

    Authors: Zhang M., Lai Y., Krupalnik V., Guo P., Guo X., Zhou J., Xu Y., Yu Z., Liu L., Jiang A., Li W., Ma G., Li N., Fu X., Lv Y., Jiang M., Tariq M., Kanwal S., Liu H., Xu X., Zhang H., Huang Y., Wang L., Chen S., Babarinde I. A., Luo Z., Wang D., Zhou T., Ward C., He M., Ibanez D. P., Li Y., Zhou J., Yuan J., Feng Y., Arumugam K., Di Vicino U., Bao X., Wu G., Schambach A., Wang H., Sun H., Gao F., Qin B., Hutchins A. P., Doble B. W., Hartmann C., Cosma M. P., Qin Y., Xu G., Chen R., Volpe G., Chen L., Hanna J. H. & Esteban M. A. (2020), Science Advances. 6, 29, 1593

  • A brick in the wall: Discovering a novel mineral component of the biofilm extracellular matrix

    Authors: Keren-Paz A. & Kolodkin-Gal I. (2020), New Biotechnology. 56, p. 9-15

  • Massive osteopetrosis caused by non-functional osteoclasts in R51Q SNX10 mutant mice

    Authors: Stein M., Barnea-Zohar M., Shalev M., Arman E., Brenner O. J., Winograd-Katz S., Gerstung J., Thalji F., Kanaan M., Elinav H., Stepensky P., Geiger B., Tuckermann J. & Elson A. (2020), Bone. 136, 115360

  • Piezo2 expressed in proprioceptive neurons is essential for skeletal integrity

    Authors: Assaraf E., Blecher R., Heinemann-Yerushalmi L., Krief S., Carmel Vinestock R., Biton I. E., Brumfeld V., Rotkopf R., Avisar E., Agar G. & Zelzer E. (2020), Nature Communications. 11, 1, 3168

  • A new MEIOB mutation is a recurrent cause for azoospermia and testicular meiotic arrest

    Authors: Gershoni M., Hauser R., Barda S., Lehavi O., Arama E., Pietrokovski S. & Kleiman S. E. (2019), Human Reproduction. 34, 4, p. 666-671

  • Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules

    Authors: Zviran A., Mor N., Rais Y., Gingold H., Peles S., Chomsky E., Viukov S., Buenrostro J. D., Scognamiglio R., Weinberger L., Manor Y. S., Krupalnik V., Zerbib M., Hezroni H., Jaitin D. A., Larastiaso D., Gilad S., Benjamin S., Gafni O., Mousa A., Ayyash M., Sheban D., Bayerl J., Aguilera-Castrejon A., Massarwa R., Maza I., Hanna S., Stelzer Y., Ulitsky I., Greenleaf W. J., Tanay A., Trumpp A., Amit I., Pilpel Y., Novershtern N. & Hanna J. H. (2019), Cell Stem Cell. 24, 2, p. 328-341.e9

  • Indole derivatives maintain the status quo between beneficial biofilms and their plant hosts

    Authors: Ganin H., Kemper N., Meir S., Rogachev I., Ely S., Massalha H., Mandabi A., Keren-Paz A., Shanzer A., Meijler M., Malitsky S., Aharoni A. & Kolodkin-Gal I. (2019), Molecular Plant-Microbe Interactions. 32, 8, p. 1013-1025

  • Phosphorylation of the phosphatase PTPROt at Tyr(399) is a molecular switch that controls osteoclast activity and bone mass in vivo

    Authors: Roth L., Wakim J., Wasserman E., Shalev M., Arman E., Stein M., Brumfeld V., Sagum C. A., Bedford M. T., Tuckermann J. & Elson A. (2019), Science Signaling. 12, 563, aau0240

  • Dynamics of cortical progenitors and production of subcerebral neurons are altered in embryos of a maternal inflammation model for autism

    Authors: Ben-Reuven L. & Reiner O. (2019), Molecular Psychiatry.

  • Interplay of LIS1 and MeCP2: Interactions and Implications With the Neurodevelopmental Disorders Lissencephaly and Rett Syndrome

    Authors: Keidar L., Gerlitz G., Kshirsagar A., Tsoory M., Olender T., Wang X., Yang Y., Chen Y., Yang Y., Voineagu I. & Reiner O. (2019), Frontiers in Cellular Neuroscience. 13, 370

  • Kinetic modeling of DUSP regulation in herceptin-resistant HER2-positive breast cancer

    Authors: Buiga P., Elson A., Tabernero L. & Schwartz J. M. (2019), Genes. 10, 8, 568

  • Building Bridges Between the Clinic and the Laboratory: A Meeting Review - Brain Malformations: A Roadmap for Future Research

    Authors: Sapir T., Barakat T. S., Paredes M. F., Lerman-Sagie T., Aronica E., Klonowski W., Nguyen L., Ben Zeev B., Bahi-Buisson N., Leventer R., Rachmian N. & Reiner O. (2019), Frontiers in Cellular Neuroscience. 13, 434

  • The people behind the papers - Shai Eyal and Elazar Zelzer

    Authors: Eyal S. & Zelzer E. (2019), Development. 146, 14, 182733

  • Modelling the role of dual specificity phosphatases in herceptin resistant breast cancer cell lines

    Authors: Buiga P., Elson A., Tabernero L. & Schwartz J. (2019), Computational Biology and Chemistry. 80, p. 138-146

  • Bone morphology is regulated modularly by global and regional genetic programs

    Authors: Eyal S., Kult S., Rubin S., Krief S., Felsenthal N., Pineault K. M., Leshkowitz D., Salame T., Addadi Y., Wellik D. M. & Zelzer E. (2019), Development. 146, 14, dev167882

  • A novel nonosteocytic regulatory mechanism of bone modeling

    Authors: Ofer L., Dean M. N., Zaslansky P., Kult S., Shwartz Y., Zaretsky J., Griess-Fishheimer S., Monsonego-Ornan E., Zelzer E. & Shahar R. (2019), PLoS Biology. 17, 2, 3000140

  • Deciphering the "m6A Code" via Antibody-Independent Quantitative Profiling

    Authors: Garcia-Campos M. A., Edelheit S., Toth U., Safra M., Shachar R., Viukov S., Winkler R., Nir R., Lasman L., Brandis A., Hanna J. H., Rossmanith W. & Schwartz S. (2019), Cell. 178, 3, p. 731-747

  • Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs

    Authors: Song Y., van den Berg P. R., Markoulaki S., Soldner F., Dall'Agnese A., Henninger J. E., Drotar J., Rosenau N., Cohen M. A., Young R. A., Semrau S., Stelzer Y. & Jaenisch R. (2019), Molecular Cell. 75, 5, p. 905-920.e6

  • Generation of Human Primordial Germ Cell-like Cells at the Surface of Embryoid Bodies from Primed-pluripotency Induced Pluripotent Stem Cells

    Authors: Mitsunaga S., Shioda K., Isselbacher K. J., Hanna J. H. & Shioda T. (2019), Jove-Journal Of Visualized Experiments. 143, e58297

  • A cancer associated somatic mutation in LC3B attenuates its binding to E1-like ATG7 protein and subsequent lipidation

    Authors: Nuta G. C., Gilad Y., Gershoni M., Sznajderman A., Schlesinger T., Bialik S., Eisenstein M., Pietrokovski S. & Kimchi A. (2019), Autophagy. 15, 3, p. 438-452

  • Stem Cell-Derived Human Gametes: The Public Engagement Imperative

    Authors: Adashi E. Y., Cohen I. G., Hanna J. H., Surani A. M. & Hayashi K. (2019), Trends in Molecular Medicine. 25, 3, p. 165-167

  • The Plant Host Induces Antibiotic Production To Select the Most-Beneficial Colonizers

    Authors: Ogran A., Yardeni E. H., Keren-Paz A., Bucher T., Jain R., Gilhar O. & Kolodkin-Gal I. (2019), Applied and Environmental Microbiology. 85, 13, UNSP e0051

  • Stage-specific requirement for Mettl3-dependent m(6)A mRNA methylation during haematopoietic stem cell differentiation

    Authors: Lee H., Bao S., Qian Y., Geula S., Leslie J., Zhang C., Hanna J. H. & Ding L. (2019), Nature Cell Biology. 21, p. 700-709

  • m6A modification controls the innate immune response to infection by targeting type I interferons

    Authors: Winkler R., Gillis E., Lasman L., Safra M., Geula S., Soyris C., Nachshon A., Tai-Schmiedel J., Friedman N., Le-Trilling V. T. K., Trilling M., Mandelboim M., Hanna J. H., Schwartz S. & Stern-Ginossar N. (2019), Nature Immunology. 20, 2, p. 173-182

  • The N-6-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy

    Authors: Dorn L. E., Lasman L., Chen J., Xu X., Hund T. J., Medvedovic M., Hanna J. H., van Berlo J. H. & Accornero F. (2019), Circulation. 139, 4, p. 533-545

  • Protein tyrosine phosphatase alpha inhibits hypothalamic leptin receptor signaling and regulates body weight in vivo

    Authors: Cohen-Sharir Y., Kuperman Y., Apelblat D., den Hertog J., Spiegel I., Knobler H. & Elson A. (2019), FASEB Journal. 33, 4, p. 5101-5111

  • An active beta-lactamase is a part of an orchestrated cell wall stress resistance network of Bacillus subtilis and related rhizosphere species

    Authors: Bucher T., Keren-Paz A., Hausser J., Olender T., Cytryn E. & Kolodkin-Gal I. (2019), Environmental Microbiology. 21, 3, p. 1068-1085

  • The HERV-K accessory protein Np9 controls viability and migration of teratocarcinoma cells

    Authors: Chan S. M., Sapir T., Park S., Rual J., Contreras-Galindo R., Reiner O. & Markovitz D. M. (2019), PLoS ONE. 14, 2, 0212970

  • Universally non-immunogenic iPSCs

    Authors: Shani T. & Hanna J. H. (2019), Nature Biomedical Engineering. 3, 5, p. 337-338

  • The roles of protein tyrosine phosphatases in bone-resorbing osteoclasts

    Authors: Shalev M. & Elson A. (2019), Biochimica Et Biophysica Acta-Molecular Cell Research. 1866, 1, p. 114-123

  • The Interactome of Palmitoyl-Protein Thioesterase 1 (PPT1) Affects Neuronal Morphology and Function

    Authors: Sapir T., Segal M., Grigoryan G., Hansson K. M., James P., Segal M. & Reiner O. (2019), Frontiers in Cellular Neuroscience. 13, 92

  • Brain organoidsA bottom-up approach for studying human neurodevelopment

    Authors: Karzbrun E. & Reiner O. (2019), Bioengineering. 6, 1, 9

  • RUNX represses Pmp22 to drive neurofibromagenesis

    Authors: Hall A., Choi K., Liu W., Rose J., Zhao C., Yu Y., Na Y., Cai Y., Coover R. A., Lin Y., Dombi E., Kim M., Levanon D., Groner Y., Boscolo E., Pan D., Liu P. P., Lu Q. R., Ratner N., Huang G. & Wu J. (2019), Science Advances. 5, 4, 8389

  • Applying the handicap principle to biofilms: condition-dependent signalling in Bacillus subtilis microbial communities

    Authors: Harris K. D. & Kolodkin-Gal I. (2019), Environmental Microbiology. 21, 2, p. 531-540

  • Common cellular origin and diverging developmental programs for different sesamoid bones

    Authors: Eyal S., Rubin S., Krief S., Levin L. & Zelzer E. (2019), Development. 146, 4, dev167452

  • A mesophilic cysteine-less split intein for protein trans-splicing applications under oxidizing conditions

    Authors: Bhagawati M., Terhorst T. M. E., Fuesser F., Hoffmann S., Pasch T., Pietrokovski S. & Mootz H. D. (2019), Proceedings of the National Academy of Sciences of the United States of America. 116, 44, p. 22164-22172

  • Regulation of dual specificity phosphatases in breast cancer during initial treatment with Herceptin: a Boolean model analysis

    Authors: Buiga P., Elson A., Tabernero L. & Schwartz J. (2018), BMC Systems Biology. 12, Suppl 1, p. 13-24, 11

  • Complement C3 Affects Rac1 Activity in the Developing Brain

    Authors: Gorelik A., Sapir T., Ben-Reuven L. & Reiner O. (2018), Frontiers in Molecular Neuroscience. 11, 150

  • An On-Chip Method for Long-Term Growth and Real-Time Imaging of Brain Organoids

    Authors: Karzbrun E., Tshuva R. Y. & Reiner O. (2018), Current Protocols in Cell Biology. 81, 1, e62

  • RAS Regulates the Transition from Naive to Primed Pluripotent Stem Cells

    Authors: Altshuler A., Verbuk M., Bhattacharya S., Abramovich I., Haklai R., Hanna J. H., Kloog Y., Gottlieb E. & Shalom-Feuerstein R. (2018), Stem Cell Reports. 10, 3, p. 1088-1101

  • Unfolding the folds: How the biomechanics of the extracellular matrix contributes to cortical gyrification

    Authors: Karlinski M. & Reiner O. (2018), Opera Medica et Physiologica. 4, 2, p. 63-70

  • Stepping out of the shadows: Oncogenic and tumor-promoting protein tyrosine phosphatases

    Authors: Elson A. (2018), International Journal of Biochemistry and Cell Biology. 96, p. 135-147

  • Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency

    Authors: Mor N., Rais Y., Sheban D., Peles S., Aguilera-Castrejon A., Zviran A., Elinger D., Viukov S., Geula S., Krupalnik V., Zerbib M., Chomsky E., Lasman L., Shani T., Bayerl J., Gafni O., Hanna S., Buenrostro J. D., Hagai T., Masika H., Vainorius G., Bergman Y., Greenleaf W. J., Esteban M. A., Elling U., Levin Y., Massarwa R., Merbl Y., Novershtern N. & Hanna J. H. (2018), Cell Stem Cell. 23, 3, p. 412-425

  • MTCH2-mediated mitochondrial fusion drives exit from naive pluripotency in embryonic stem cells

    Authors: Bahat A., Goldman A., Zaltsman Y., Khan D. H., Halperin C., Amzallag E., Krupalnik V., Mullokandov M., Silberman A., Erez A., Schimmer A. D., Hanna J. H. & Gross A. (2018), Nature Communications. 9, 1, 5132

  • NKp46 Receptor-Mediated Interferon-gamma Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis

    Authors: Glasner A., Levi A., Enk J., Isaacson B., Viukov S., Orlanski S., Scope A., Neuman T., Enk C. D., Hanna J. H., Sexl V., Jonjic S., Seliger B., Zitvogel L. & Mandelboim O. (2018), Immunity. 48, 1, p. 107-+

  • Micro-CT X-ray imaging exposes structured diffusion barriers within biofilms

    Authors: Keren-Paz A., Brumfeld V., Oppenheimer-Shaanan Y. & Kolodkin-Gal I. (2018), npj Biofilms and Microbiomes. 4, 8

  • Novel antibiofilm chemotherapies target nitrogen from glutamate and glutamine

    Authors: Hassanov T., Karunker I., Steinberg N., Erez A. & Kolodkin-Gal I. (2018), Scientific Reports. 8, 1, 7097

  • Human brain organoids on a chip reveal the physics of folding

    Authors: Karzbrun E., Kshirsagar A., Cohen S. R., Hanna J. H. & Reiner O. (2018), Nature Physics. 14, 5, p. 515-522

  • New functions for the proprioceptive system in skeletal biology

    Authors: Blecher R., Heinemann-Yerushalmi L., Assaraf E., Konstantin N., Chapman J. R., Cope T. C., Bewick G. S., Banks R. W. & Zelzer E. (2018), Philosophical Transactions of the Royal Society B: Biological Sciences. 373, 1759, 20170327

  • Human brain organoids on a chip to study development and disease

    Authors: Karzbrun E., Kshirsagar A. & Reiner O. (2018), Opera Medica et Physiologica. 4, p. 12

  • Development of migrating tendon-bone attachments involves replacement of progenitor populations

    Authors: Felsenthal N., Rubin S., Stern T., Krief S., Pal D., Pryce B. A., Schweitzer R. & Zelzer E. (2018), Development. 145, 24, 165381

  • Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies

    Authors: Gamliel M., Goldman-Wohl D., Isaacson B., Gur C., Stein N., Yamin R., Berger M., Grunewald M., Keshet E., Rais Y., Bornstein C., David E., Jelinski A., Eisenberg I., Greenfield C., Ben-David A., Imbar T., Gilad R., Haimov-Kochman R., Mankuta D., Elami-Suzin M., Amit I., Hanna J. H., Yagel S. & Mandelboim O. (2018), Immunity. 48, 5, p. 951-962.e5

  • Collective Vortex-Like Movement of Bacillus subtilis Facilitates the Generation of Floating Biofilms

    Authors: Steinberg N., Rosenberg G., Keren-Paz A. & Kolodkin-Gal I. (2018), Frontiers in Microbiology. 9, 590

  • Cortical progenitor biology: key features mediating proliferation versus differentiation

    Authors: Uzquiano A., Gladwyn-Ng I., Nguyen L., Reiner O., Goetz M., Matsuzaki F. & Francis F. (2018), Journal of Neurochemistry. 146, 5, p. 500-525

  • Notch Activation by Shootin1 Opposing Activities on 2 Ubiquitin Ligases

    Authors: Sapir T., Levy T., Kozer N., Shin I., Zamor V., Haffner-Krausz R., McGlade J. C. & Reiner O. (2018), Cerebral Cortex. 28, 9, p. 3115-3128

  • The Role of m(6)A/m-RNA Methylation in Stress Response Regulation

    Authors: Engel M., Eggert C., Kaplick P. M., Eder M., Roeh S., Tietze L., Namendorf C., Arloth J., Weber P., Rex-Haffner M., Geula S., Jakovcevski M., Hanna J. H., Leshkowitz D., Uhr M., Wotjak C. T., Schmidt M. V., Deussing J. M., Binder E. B. & Chen A. (2018), Neuron. 99, 2, p. 389-403.e9

  • Modulating cell state to enhance suspension expansion of human pluripotent stem cells

    Authors: Lipsitz Y. Y., Woodford C., Yin T., Hanna J. H. & Zandstra P. W. (2018), Proceedings Of The National Academy Of Sciences Of The United States Of America-Biological Sciences. 115, 25, p. 6369-6374

  • A Coated Sponge: Toward Neonatal Brain Repair

    Authors: Reiner O. & Sapir T. (2018),

  • The PTPROt tyrosine phosphatase functions as an obligate haploinsufficient tumor suppressor in vivo in B-cell chronic lymphocytic leukemia

    Authors: Wakim J., Arman E., Becker Herman S., Kramer M. P., Bakos E., Shachar I. & Elson A. (2017), Oncogene. 36, 26, p. 3686-3694

  • A multiplexed screening method for pluripotency

    Authors: Plotnikov A., Kozer N., Krupalnik V., Peles S., Mor N., Rais Y., Hanna J. H. & Barr H. M. (2017), Stem Cell Research. 23, p. 158-162

  • Runx3 in Immunity, Inflammation and Cancer

    Authors: Lotem J., Levanon D., Negreanu V., Bauer O., Hantisteanu S., Dicken J. & Groner Y. (2017), RUNX PROTEINS IN DEVELOPMENT AND CANCER. VanWijnen A., Neil JC., Speck NA., Liu P., Groner Y. & Ito Y. (eds.). p. 369-393 (trueAdvances in Experimental Medicine and Biology).

  • Increased NK cell immunity in a transgenic mouse model of NKp46 overexpression

    Authors: Glasner A., Isaacson B., Viukov S., Neuman T., Friedman N., Mandelboim M., Sexl V., Hanna J. H. & Mandelboim O. (2017), Scientific Reports. 7, 1, 13090

  • m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover

    Authors: Ke S., Pandya-Jones A., Saito Y., Fak J. J., Vagbo C. B., Geula S., Hanna J. H., Black D. L., Darnell J. E. & Darnell R. B. (2017), GENES & DEVELOPMENT. 31, 10, p. 990-1006

  • From Prokaryotes to Cancer: Glutamine Flux in Multicellular Units

    Authors: Erez A. & Kolodkin-Gal I. (2017), Trends in Endocrinology and Metabolism. 28, 9, p. 637-644

  • Beyond the wall: can D-amino acids and small molecule inhibitors eliminate infections?

    Authors: Kolodkin-Gal I. (2017), Future Medicinal Chemistry. 9, 9, p. 843-846

  • Architects of nature: growing buildings with bacterial biofilms

    Authors: Dade-Robertson M., Keren-Paz A., Zhang M. & Kolodkin-Gal I. (2017), Microbial Biotechnology. 10, 5, p. 1157-1163

  • OCT4 impedes cell fate redirection by the melanocyte lineage master regulator MITF in mouse ESCs

    Authors: Sheinboim D., Maza I., Dror I., Parikh S., Krupalnik V., Bell R. E., Zviran A., Suita Y., Hakim O., Mandel-Gutfreund Y., Khaled M., Hanna J. H. & Levy C. (2017), Nature Communications. 8, 1, 1022

  • Developmental activities of the complement pathway in migrating neurons

    Authors: Gorelik A., Sapir T., Haffner-Krausz R., Olender T., Woodruff T. M. & Reiner O. (2017), Nature Communications. 8, 15096

  • Serping1/C1 inhibitor affects cortical development in a cell autonomous and non-cell autonomous manner

    Authors: Gorelik A., Sapir T., Woodruff T. M. & Reiner O. (2017), Frontiers in Cellular Neuroscience. 11, 169

  • Protective role of soluble receptor for advanced glycation end-products in patients with non-alcoholic fatty liver disease

    Authors: Zelber-Sagi S., Salomone F., Kolodkin-Gal I., Erez N., Buch A., Yeshua H., Webb M., Halpern Z. & Shibolet O. (2017), Digestive and Liver Disease. 49, 5, p. 523-529

  • The landscape of sex-differential transcriptome and its consequent selection in human adults

    Authors: Gershoni M. & Pietrokovski S. (2017), BMC Biology. 15, 1, 7

  • Bacilli glutamate dehydrogenases diverged via coevolution of transcription and enzyme regulation

    Authors: Noda Garcia G. L., Romero M. L. R., Longo L. M., Kolodkin-Gal I. & Tawfik D. (2017), EMBO Reports. 18, 7, p. 1139-1149

  • The Proprioceptive System Regulates Morphologic Restoration of Fractured Bones

    Authors: Blecher R., Krief S., Galili T., Assaraf E., Stern T., Anekstein Y., Agar G. & Zelzer E. (2017), Cell Reports. 20, 8, p. 1775-1783

  • Identification and Characterization of Differentially-Regulated Type IVb Pilin Genes Necessary for Predation in Obligate Bacterial Predators /631/326/1320 /631/326/325 /38 article

    Authors: Avidan O., Petrenko M., Becker R., Beck S., Linscheid M., Pietrokovski S. & Jurkevitch E. (2017), Scientific Reports. 7, 1, 1013

  • Transcriptional programs that control expression of the autoimmune regulator gene Aire

    Authors: Herzig Y., Nevo S., Bornstein C., Brezis M. R., Ben-Hur S., Shkedy A., Eisenberg-Bord M., Levi B., Delacher M., Goldfarb Y., David E., Weinberger L., Viukov S., Ben-Dor S., Giraud M., Hanna J. H., Breiling A., Lyko F., Amit I., Feuerer M. & Abramson J. (2017), Nature Immunology. 18, 2, p. 161-172

  • Development of a screening system for inteins active in protein splicing based on intein insertion into the LacZ alpha-peptide

    Authors: Neugebauer M., Bocker J., Matern J., Pietrokovski S. & Mootz H. (2017), Biological Chemistry. 398, 1, p. 57-67

  • A familial study of azoospermic men identifies three novel causative mutations in three new human azoospermia genes

    Authors: Gershoni M., Hauser R., Yogev L., Lehavi O., Azem F., Yavetz H., Pietrokovski S. & Kleiman S. E. (2017), Genetics in Medicine. 19, 9, p. 998-1006

  • Mechanical regulation of musculoskeletal system development

    Authors: Felsenthal N. & Zelzer E. (2017), Development (Cambridge). 144, 23, p. 4271-4283

  • The Leo Sachs legacy: A pioneers journey through hematopoiesis

    Authors: Lotem J. & Groner Y. (2017), International Journal of Developmental Biology. 61, 3-5, p. 127-136

  • The Proprioceptive System Masterminds Spinal Alignment: Insight into the Mechanism of Scoliosis

    Authors: Blecher R., Krief S., Galili T., Biton I. E., Stern T., Assaraf E., Levanon D., Appel E., Anekstein Y., Agar G., Groner Y. & Zelzer E. (2017), Developmental Cell. 42, 4, p. 388-399.e3

  • Proteomics insights into infantile neuronal ceroid lipofuscinosis (CLN1) point to the involvement of cilia pathology in the disease

    Authors: Segal Salto S. M., Hansson K., Sapir T., Kaplan A., Levy T., Schweizer M., Frotscher M., James P. & Reiner O. (2017), Human Molecular Genetics. 26, 9, p. 1678-1693

  • Relevance of iPSC-derived human PGC-like cells at the surface of embryoid bodies to prechemotaxis migrating PGCs

    Authors: Mitsunaga S., Odajima J., Yawata S., Shioda K., Owa C., Isselbacher K. J., Shioda T. & Hanna J. (. (2017), Proceedings Of The National Academy Of Sciences Of The United States Of America-Physical Sciences. 114, 46, p. E9913-E9922

  • Receptor Protein Tyrosine Phosphatase alpha-Mediated Enhancement of Rheumatoid Synovial Fibroblast Signaling and Promotion of Arthritis in Mice

    Authors: Stanford S. M., Svensson M. N. D., Sacchetti C., Pilo C. A., Wu D. J., Kiosses W. B., Hellvard A., Bergum B., Muench G. R. A., Elly C., Liu Y., den Hertog J., Elson A., Sap J., Mydel P., Boyle D. L., Corr M., Firestein G. S. & Bottini N. (2016), Arthritis & Rheumatology. 68, 2, p. 359-369

  • Modeling the autistic cell: iPSCs recapitulate developmental principles of syndromic and nonsyndromic ASD

    Authors: Ben-Reuven L. & Reiner O. (2016), Development Growth and Differentiation. 58, 5, p. 481-491

  • Corrigendum: Failure to replicate the STAP cell phenomenon (vol 525, pg E6, 2015)

    Authors: De Los Angeles A., Ferrari F., Fujiwara Y., Mathieu R., Lee S., Lee S., Tu H., Ross S., Chou S., Minh Nguyen, Wu Z., Theunissen T. W., Powell B. E., Imsoonthornruksa S., Chen J., Borkent M., Krupalnik V., Lujan E., Wernig M., Hanna J. H., Hochedlinger K., Pei D., Jaenisch R., Deng H., Orkin S. H., Park P. J. & Daley G. Q. (2016),

  • Parent-of-Origin DNA Methylation Dynamics during Mouse Development

    Authors: Stelzer Y., Wu H., Song Y., Shivalila C. S., Markoulaki S. & Jaenisch R. (2016), Cell reports (Cambridge). 16, 12, p. 3167-3180

  • Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs

    Authors: Chen J., Shishkin A. A., Zhu X., Kadri S., Maza I., Guttman M., Hanna J. H., Regev A. & Garber M. (2016), GENOME BIOLOGY. 17, 1, 19

  • PTH Induces Systemically Administered Mesenchymal Stem Cells to Migrate to and Regenerate Spine Injuries

    Authors: Sheyn D., Shapiro G., Tawackoli W., Jun D. S., Koh Y., Kang K. B., Su S., Da X., Ben-David S., Bez M., Yalon E., Antebi B., Avalos P., Stern T., Zelzer E., Schwarz E. M., Gazit Z., Pelled G., Bae H. M. & Gazit D. (2016), Molecular Therapy. 24, 2, p. 318-330

  • Production of Osteoclasts for Studying Protein Tyrosine Phosphatase Signaling

    Authors: Finkelshtein E., Levy-Apter E. & Elson A. (2016), Protein Tyrosine Phosphatases. Pulido R. (eds.). p. 283-300 (trueMethods in Molecular Biology).

  • Not so simple, not so subtle: The interspecies competition between Bacillus simplex and Bacillus subtilis and its impact on the evolution of biofilms

    Authors: Rosenberg G., Steinberg N., Oppenheimer-Shaanan Y., Olender T., Doron S., Ben-Ari J., Sirota-Madi A., Bloom-Ackermann Z. & Kolodkin-Gal I. (2016), npj Biofilms and Microbiomes. 2, 15027

  • Regulation of receptor-type protein tyrosine phosphatases by their C-terminal tail domains

    Authors: Barnea M., Olender T., Bedford M. T. & Elson A. (2016), Biochemical Society Transactions. 44, 5, p. 1295-1303

  • Toxin-Antitoxin systems eliminate defective cells and preserve symmetry in Bacillus subtilis biofilms

    Authors: Bloom-Ackermann Z., Steinberg N., Rosenberg G., Oppenheimer-Shaanan Y., Pollack D., Ely S., Storzi N., Levy A. & Kolodkin-Gal I. (2016), Environmental Microbiology. 18, 12, p. 5032-5047

  • Editing DNA Methylation in the Mammalian Genome

    Authors: Liu X. S., Wu H., Ji X., Stelzer Y., Wu X., Czauderna S., Shu J., Dadon D., Young R. A. & Jaenisch R. (2016), Cell (Cambridge). 167, 1, p. 233-247.e17

  • An ensemble of regulatory elements controls Runx3 spatiotemporal expression in subsets of dorsal root ganglia proprioceptive neurons

    Authors: Appe E., Weissmann S., Salzberg Y., Orlovsky K., Negreanu V., Tsoory M., Raanan C., Feldmesser E., Bernstein Y., Wolstein O., Levanon D. & Groner Y. (2016), GENES & DEVELOPMENT. 30, 23, p. 2607-2622

  • Dynamic stem cell states: Naive to primed pluripotency in rodents and humans

    Authors: Weinberger L., Ayyash M., Novershtern N. & Hanna J. (2016), Nature Reviews Molecular Cell Biology. 17, 3, p. 155-169

  • Deposition of collagen type I onto skeletal endothelium reveals a new role for blood vessels in regulating bone morphology

    Authors: Ben Shoham S. A., Rot C., Stern T., Krief S., Akiva A., Dadosh T., Sabany H., Lu Y., Kadler K. E. & Zelzer E. (2016), Development (Cambridge). 143, 21, p. 3933-3943

  • An extended cyclic di-GMP network in the predatory bacterium Bdellovibrio bacteriovorus

    Authors: Rotem O., Nesper J., Borovok I., Gorovits R., Kolot M., Pasternak Z., Shin I., Glatter T., Pietrokovski S., Jenal U. & Jurkevitch E. (2016), Journal of Bacteriology. 198, 1, p. 127-137

  • Joint Development Involves a Continuous Influx of Gdf5-Positive Cells

    Authors: Shwartz Y., Viukov S., Krief S. & Zelzer E. (2016), Cell Reports. 15, 12, p. 2577-2587

  • Reversible cysteine acylation regulates the activity of human palmitoyl-protein thioesterase 1 (PPT1)

    Authors: Segal-Salto M., Sapir T. & Reiner O. (2016), PLoS ONE. 11, 1, e0146466

  • Transport of membrane-bound mineral particles in blood vessels during chicken embryonic bone development

    Authors: Kerschnitzki M., Akiva A., Ben Shoham S. A., Koifman N., Shimoni E., Rechav K., Arraf A. A., Schultheiss T. M., Talmon Y., Zelzer E., Weiner S. & Addadi L. (2016), Bone. 83, p. 65-72

  • Quorum-sensing Cascades Governing Bacterial Multicellular Communities

    Authors: Bloom-Ackermann Z., Ganin H. & Kolodkin-Gal I. (2016), Israel Journal of Chemistry. 56, 5, p. 302-309

  • Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression

    Authors: Soldner F., Stelzer Y., Shivalila C. S., Abraham B. J., Latourelle J. C., Barrasa M. I., Goldmann J., Myers R. H., Young R. A. & Jaenisch R. (2016), Nature (London). 533, 7601, p. 95-99

  • Eradication of Enterococcus faecalis Biofilms on Human Dentin

    Authors: Rosen E., Tsesis I., Elbahary S., Storzi N. & Kolodkin-Gal I. (2016), Frontiers in Microbiology. 7

  • Escherichia coli quorum-sensing EDF, a peptide generated by novel multiple distinct mechanisms and regulated by trans-translation

    Authors: Kumar S., Kolodkin-Gal I., Vesper O., Alam N., Schueler-Furman O., Moll I. & Engelberg-Kulka H. (2016), mBio. 7, 1, 02034-15

  • Cancer therapeutic approach based on conformational stabilization of mutant p53 protein by small peptides

    Authors: Tal P., Eizenberger S., Cohen E., Goldfinger N., Pietrokovski S., Oren M. & Rotter V. (2016), Oncotarget. 7, 11, p. 11817-11837

  • Co-ChIP enables genome-wide mapping of histone mark co-occurrence at single-molecule resolution

    Authors: Weiner A., Lara Astiaso A. D., Krupalnik V., Gafni O., David E., Winter D. R., Hanna J. H. & Amit I. (2016), Nature biotechnology. 34, 9, p. 953-961

  • An essential role for UTX in resolution and activation of bivalent promoters

    Authors: Dhar S. S., Lee S., Chen K., Zhu G., Oh W., Allton K., Gafni O., Kim Y. Z., Tomoiga A. S., Barton M. C., Hanna J. H., Wang Z., Li W. & Lee M. G. (2016), Nucleic Acids Research. 44, 8, p. 3659-3674

  • Regulation of neuronal migration, an emerging topic in autism spectrum disorders

    Authors: Reiner O., Karzbrun E., Kshirsagar A. & Kaibuchi K. (2016), Journal of Neurochemistry. 136, 3, p. 440-456

  • Spatio-Temporal assembly of functional mineral scaffolds within microbial biofilms

    Authors: Oppenheimer-Shaanan Y., Sibony-Nevo O., Bloom-Ackermann Z., Suissa R., Steinberg N., Kartvelishvily E., Brumfeld V. & Kolodkin-Gal I. (2016), npj Biofilms and Microbiomes. 2, 15031

  • Development of a subset of forelimb muscles and their attachment sites requires the ulnar-mammary syndrome gene Tbx3

    Authors: Colasanto M. P., Eyal S., Mohassel P., Bamshad M., Bonnemann C. G., Zelzer E., Moon A. M. & Kardon G. (2016), Disease Models & Mechanisms. 9, 11, p. 1257-1269

  • Tracing Dynamic Changes of DNA Methylation at Single-Cell Resolution

    Authors: Stelzer Y., Shivalila C. S., Soldner F., Markoulaki S. & Jaenisch R. (2015), Cell (Cambridge). 163, 1, p. 218-229

  • The spinal muscular atrophy with pontocerebellar hypoplasia gene VRK1 regulates neuronal migration through an Amyloid-β precursor protein-dependent mechanism

    Authors: Vinograd-Byk H., Sapir T., Cantarero L., Lazo P. A., Zeligson S., Lev D., Lerman-Sagie T., Renbaum P., Reiner O. & Levy-Lahad E. (2015), Journal of Neuroscience. 35, 3, p. 936-942

  • The Matrix Reloaded: How Sensing the Extracellular Matrix Synchronizes Bacterial Communities

    Authors: Steinberg N. & Kolodkin-Gal I. (2015), Journal of Bacteriology. 197, 13, p. 2092-2103

  • Disturbance of the bacterial cell wall specifically interferes with biofilm formation

    Authors: Bucher T., Oppenheimer-Shaanan Y., Savidor A., Bloom-Ackermann Z. & Kolodkin-Gal I. (2015), Environmental Microbiology Reports. 7, 6, p. 990-1004

  • SOX17 is a critical specifier of human primordial germ cell fate

    Authors: Irie N., Weinberger L., Tang W. W., Kobayashi T., Viukov S., Manor Y. S., Dietmann S., Hanna J. H. & Surani M. A. (2015), Cell. 160, 1-2, p. 253-268

  • Non-cell autonomous and non-catalytic activities of ATX in the developing brain

    Authors: Greenman R., Gorelik A., Sapir T., Baumgart J., Zamor V., Segal Salto S. M., Levin-Zaidman S., Aidinis V., Aoki J., Nitsch R., Vogt J. & Reiner O. (2015), Frontiers in Neuroscience. 9, MAR, 53

  • Derivation of novel human ground state naive pluripotent stem cells (vol 504, pg 282, 2013): Derivation of novel human ground state naive pluripotent stem cells

    Authors: Gafni O., Weinberger L., Mansour A. A., Manor Y. S., Chomsky E., Ben-Yosef D., Kalma Y., Viukov S., Maza I., Zviran A., Rais Y., Shipony Z., Mukamel Z., Krupalnik V., Zerbib M., Geula S., Caspi I., Schneir D., Shwartz T., Gilad S., Amann-Zalcenstein D., Benjamin S., Amit I., Tanay A., Massarwa R., Novershtern N. & Hanna J. H. (2015), Nature. 520, 7549, p. 710

  • Lymphatic vessels arise from specialized angioblasts within a venous niche

    Authors: Nicenboim J., Malkinson G., Lupo T., Asaf L., Sela Y., Mayseless O., Gibbs-Bar L., Senderovich N., Hashimshony T., Shin M. S., Jerafi-Vider A., Avraham-Davidi I., Krupalnik V., Hofi R., Almog G., Astin J. W., Golani O., Ben-Dor S., Crosier P. S., Herzog W., Lawson N. D., Hanna J. H., Yanai I. & Yaniv K. (2015), Nature. 522, 7554, p. 56-61

  • Cell-cycle progress in obligate predatory bacteria is dependent upon sequential sensing of prey recognition and prey quality cues

    Authors: Rotem O., Pasternak Z., Shimoni E., Belausov E., Porat Z., Pietrokovski S. & Jurkevitch E. (2015), Proceedings of the National Academy of Sciences of the United States of America. 112, 44, p. E6028-E6037

  • m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

    Authors: Geula S., Moshitch-Moshkovitz S., Dominissini D., Mansour A. A., Kol N., Salmon-Divon M., Hershkovitz V., Peer E., Mor N., Manor Y. S., Ben-Haim M., Eyal E., Yunger S., Pinto Y., Jaitin D. A., Viukov S., Rais Y., Krupalnik V., Chomsky E., Zerbib M., Maza I., Rechavi Y., Massarwa R., Hanna S., Amit I., Levanon E. Y., Amariglio N., Stern-Ginossar N., Novershtern N., Rechavi G. & Hanna J. H. (2015), Science. 347, 6225, p. 1002-1006

  • On the development of the patella

    Authors: Eyal S., Blitz E., Shwartz Y., Akiyama H., Schweitzer R. & Zelzer E. (2015), Development (Cambridge). 142, 10, p. 1831-1839

  • Runx1 Transcription Factor Is Required for Myoblasts Proliferation during Muscle Regeneration

    Authors: Umansky K., Gruenbaum-Cohen Y., Tsoory M., Feldmesser E., Goldenberg D., Brenner O. & Groner Y. (2015), PLoS Genetics. 11, 8, e1005457

  • Runx3 at the interface of immunity, inflammation and cancer

    Authors: Lotem J., Levanon D., Negreanu V., Bauer O., Hantisteanu S., Dicken J. & Groner Y. (2015), Biochimica Et Biophysica Acta-Reviews On Cancer. 1855, 2, p. 131-143

  • Failure to replicate the STAP cell phenomenon

    Authors: De Los Angeles L. A. A., Ferrari F., Fujiwara Y., Mathieu R., Lee S., Lee S., Tu H., Ross S., Chou S., Nguyen M., Wu Z., Theunissen T. W., Powell B. E., Imsoonthornruksa S., Chen J., Borkent M., Krupalnik V., Lujan E., Wernig M., Hanna J. H., Hochedlinger K., Pei D., Jaenisch R., Deng H., Orkin S. H., Park P. J. & Daley G. Q. (2015), Nature. 525, 7570, p. E6-E9

  • Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors

    Authors: Maza I., Caspi I., Zviran A., Chomsky E., Rais Y., Viukov S., Geula S., Buenrostro J., Weinberger L., Krupalnik V., Hanna S., Zerbib M., Dutton J., Greenleaf W., Massarwa R., Novershtern N. & Hanna J. (2015), Nature biotechnology. 33, 7, p. 769-774

  • Absence of α-and β-dystroglycan is associated with Walker-Warburg syndrome

    Authors: Riemersma M., Mandel H., Van Beusekom E., Gazzoli I., Roscioli T., Eran A., Gershoni-Baruch R., Gershoni M., Pietrokovski S., Vissers L. E., Lefeber D. J., Willemsen M. A., Wevers R. A. & Van Bokhoven H. (2015), Neurology. 84, 21, p. 2177-2182

  • Vascular patterning regulates interdigital cell death by a ros-mediated mechanism

    Authors: Eshkar-Oren I., Krief S., Ferrara N., Elliott A. M. & Zelzer E. (2015), Development (Cambridge). 142, 4, p. 672-680

  • Deterministic direct reprogramming of somatic cells to pluripotency (vol 502, pg 65, 2013): Deterministic direct reprogramming of somatic cells to pluripotency (Nature (2013) 502 (65-70) DOI: 10.1038/nature12587)

    Authors: Rais Y., Zviran A., Geula S., Gafni O., Chomsky E., Viukov S., Mansour A. A., Caspi I., Krupalnik V., Zerbib M., Maza I., Mor N., Baran D., Weinberger L., Jaitin D. A., Lara-Astiaso D., Blecher-Gonen R., Shipony Z., Mukamel Z., Hagai T., Gilad S., Amann-Zalcenstein D., Tanay A., Amit I., Novershtern N. & Hanna J. H. (2015), Nature. 520, 7549, p. 710-710

  • Differentiation of human parthenogenetic pluripotent stem cells reveals multiple tissue- and isoform-specific imprinted transcripts

    Authors: Stelzer Y., Bar S., Bartok O., Afik S., Ronen D., Kadener S. & Benvenisty N. (2015), Cell reports (Cambridge). 11, 2, p. 308-320

  • Genomic-wide transcriptional profiling in primary myoblasts reveals Runx1-regulated genes in muscle regeneration

    Authors: Umansky K. B., Feldmesser E. & Groner Y. (2015), Genomics Data. 6, p. 120-122

  • Loss of osteoblast Runx3 produces severe congenital osteopenia

    Authors: Bauer O., Sharir A., Kimura A., Hantisteanu S., Takeda S. & Groner Y. (2015), Molecular and Cellular Biology. 35, 7, p. 1097-1109

  • Isometric scaling in developing long bones is achieved by an optimal epiphyseal growth balance

    Authors: Stern T., Aviram R., Rot C., Galili T., Sharir A., Achrai N. K., Keller Y., Shahar R. & Zelzer E. (2015), PLoS Biology. 13, 8, A014

  • Artificial Sweeteners Induce Glucose Intolerance by Altering the Gut Microbiota: Editorial comment

    Authors: Suez J., Korem T., Zeevi D., Zilberman-Schapira G., Thaiss C. A., Maza O., Israeli D., Zmora N., Gilad S., Weinberger A., Kuperman Y., Harmelin A., Kolodkin-Gal I., Shapiro H., Halpern Z., Segal E. & Elinav E. (2015),

  • A pathway to bone: Signaling molecules and transcription factors involved in chondrocyte development and maturation

    Authors: Kozhemyakina E., Lassar A. B. & Zelzer E. (2015), Development (Cambridge). 142, 5, p. 817-831

  • Artificial sweeteners induce glucose intolerance by altering the gut microbiota

    Authors: Suez J., Korem T., Zeevi D., Zilberman-Schapira G., Thaiss C. A., Maza O., Israeli D., Zmora N., Gilad S., Weinberger A., Kuperman Y., Harmelin A., Kolodkin-Gal I., Shapiro H., Halpern Z., Segal E. & Elinav E. (2014), Nature. 514, 7521, p. 181-186

  • Adaptor protein GRB2 promotes Src tyrosine kinase activation and podosomal organization by protein-tyrosine phosphatase ∈ in osteoclasts

    Authors: Levy-Apter E., Finkelshtein E., Vemulapalli V., Li S. S. -., Bedford M. T. & Elson A. (2014), Journal of Biological Chemistry. 289, 52, p. 36048-36058

  • Protein tyrosine phosphatases ε and α perform nonredundant roles in osteoclasts

    Authors: Finkelshtein E., Lotinun S., Levy-Apter E., Arman E., den Hertog J., Baron R. & Elson A. (2014), Molecular Biology of the Cell. 25, 11, p. 1808-1818

  • Nonradioactive in situ hybridization on skeletal tissue sections

    Authors: Shwartz Y. & Zelzer E. (2014), Skeletal Development and Repair. Hilton M. (eds.). p. 203-215

  • Correction: Systematic identification of culture conditions for induction and maintenance of naive human pluripotency (Cell Stem Cell (2014) 15 (471-487))

    Authors: Theunissen T. W., Powell B. E., Wang H., Mitalipova M., Faddah D. A., Reddy J., Fan Z. P., Maetzel D., Ganz K., Shi L., Lungjangwa T., Imsoonthornruksa S., Stelzer Y., Rangarajan S., D'Alessio A., Zhang J., Gao Q., Dawlaty M. M., Young R. A., Gray N. S. & Jaenisch R. (2014),

  • A mechanical jack-like mechanism drives spontaneous fracture healing in neonatal mice

    Authors: Rot C., Stern T., Blecher R., Friesem B. & Zelzer E. (2014), Developmental Cell. 31, 2, p. 159-170

  • Lucky iPSCs

    Authors: Zviran A. & Hanna J. H. (2014), GENOME BIOLOGY. 15, 3, 109

  • Systematic identification of culture conditions for induction and maintenance of naive human pluripotency

    Authors: Theunissen T. W., Powell B. E., Wang H., Mitalipova M., Faddah D. A., Reddy J., Fan Z. P., Maetzel D., Ganz K., Shi L., Lungjangwa T., Imsoonthornruksa S., Stelzer Y., Rangarajan S., D'Alessio A., Zhang J., Gao Q., Dawlaty M. M., Young R. A., Gray N. S. & Jaenisch R. (2014), Cell Stem Cell. 15, 4, p. 471-487

  • Pioneer of hematopoietic colony-stimulating factors: Leo Sachs (1924-2013).

    Authors: Sela M. & Groner Y. (2014), Unknown Journal. 111, 5, p. 1664-1665

  • Erratum: Systematic identification of culture conditions for induction and maintenance of naive human pluripotency (Cell Stem Cell (2014) 15 (471-487))

    Authors: Theunissen T. W., Powell B. E., Wang H., Mitalipova M., Faddah D. A., Reddy J., Fan Z. P., Maetzel D., Ganz K., Shi L., Lungjangwa T., Imsoonthornruksa S., Stelzer Y., Rangarajan S., D'Alessio A., Zhang J., Gao Q., Dawlaty M. M., Young R. A., Gray N. S. & Jaenisch R. (2014),

  • Tendon-to-bone attachment: From development to maturity

    Authors: Zelzer E., Blitz E., Killian M. L. & Thomopoulos S. (2014), Birth Defects Research Part C-Embryo Today-Reviews. 102, 1, p. 101-112

  • Metabolic regulation by protein tyrosine phosphatases

    Authors: Knobler H. Y. & Elson A. (2014), Journal of Biomedical Research. 28, 3, p. 157-168

  • Reduced selection and accumulation of deleterious mutations in genes exclusively expressed in men

    Authors: Gershoni M. & Pietrokovski S. (2014), Nature Communications. 5, 4438

  • An atypical naturally split intein engineered for highly efficient protein labeling

    Authors: Thiel I. V., Volkmann G., Pietrokovski S. & Mootz H. D. (2014), ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 53, 5, p. 1306-1310

  • Passage number is a major contributor to genomic structural variations in mouse iPSCs

    Authors: Liu P., Kaplan A., Yuan B., Hanna J. H., Lupski J. R. & Reiner O. (2014), Stem Cells. 32, 10, p. 2657-2667

  • Transcription factor Runx3 regulates interleukin-15-dependent natural Killer cell activation

    Authors: Levanon D., Negreanu V., Lotem J., Bone K. R., Brenner O., Leshkowitz D. & Groner Y. (2014), Molecular and Cellular Biology. 34, 6, p. 1158-1169

  • Mark/Par-1 marking the polarity of migrating neurons

    Authors: Reiner O. & Sapir T. (2014), Cellular and Molecular Control of Neuronal Migration. p. 97-111

  • The noncoding RNA IPW regulates the imprinted DLK1-DIO3 locus in an induced pluripotent stem cell model of Prader-Willi syndrome

    Authors: Stelzer Y., Sagi I., Yanuka O., Eiges R. & Benvenisty N. (2014), Nature Genetics. 46, 6, p. 551-557

  • In and out: an analysis of epibiotic vs periplasmic bacterial predators

    Authors: Pasternak Z., Njagi M., Shani Y., Chanyi R., Rotem O., Lurie-Weinberger M. N., Koval S., Pietrokovski S., Gophna U. & Jurkevitch E. (2014), ISME Journal. 8, 3, p. 625-635

  • Endothelial cells regulate neural crest and second heart field morphogenesis

    Authors: Milgrom-Hoffman M., Michailovici I., Ferrara N., Zelzer E. & Tzahor E. (2014), Biology Open. 3, 8, p. 679-688

  • Carcinogen-induced skin tumor development requires leukocytic expression of the transcription factor Runx3

    Authors: Bauer O., Hantisteanu S., Lotem J. & Groner Y. (2014), Cancer Prevention Research. 7, 9, p. 913-926

  • Stem cells: The quest for the perfect reprogrammed cell

    Authors: Krupalnik V. & Hanna J. H. (2014),

  • Identification of novel imprinted differentially methylated regions by global analysis of human-parthenogenetic-induced pluripotent stem cells

    Authors: Stelzer Y., Ronen D., Bock C., Boyle P., Meissner A. & Benvenisty N. (2013), Stem Cell Reports. 1, 1, p. 79-89

  • Small molecules are natural triggers for the disassembly of biofilms

    Authors: Oppenheimer-Shaanan Y., Steinberg N. & Kolodkin-Gal I. (2013), Trends in Microbiology. 21, 11, p. 594-601

  • Protein tyrosine phosphatases as novel targets in breast cancer therapy

    Authors: Nunes-Xavier C. E., Martin-Perez J., Elson A. & Pulido R. (2013), Biochimica et Biophysica Acta - Reviews on Cancer. 1836, 2, p. 211-226

  • Protein tyrosine phosphatases in health and disease

    Authors: Hendriks W. J. A. J., Elson A., Harroch S., Pulido R., Stoker A. & den Hertog J. (2013), FEBS Journal. 280, 2, p. 708-730

  • Repositioning forelimb superficialis muscles: Tendon attachment and muscle activity enable active relocation of functional myofibers

    Authors: Huang A. H., Riordan T. J., Wang L., Eyal S., Zelzer E., Brigande J. V. & Schweitzer R. (2013), Developmental Cell. 26, 5, p. 544-551

  • Nucleokinesis

    Authors: Reiner O. & Gerlitz G. (2013), Cellular Migration and Formation of Neuronal Connections. p. 261-279

  • Protein Tyrosine Phosphatase Epsilon as a Regulator of Body Weight and Glucose Metabolism

    Authors: Elson A. (2013), Protein Tyrosine Phosphatase Control of Metabolism. Bence K. K. (eds.). p. 187-202

  • Derivation of novel human ground state naive pluripotent stem cells

    Authors: Gafni O., Weinberger L., Mansour A. A., Manor Y. S., Chomsky E., Ben-Yosef D., Kalma Y., Viukov S., Maza I., Zviran A., Rais Y., Shipony Z., Mukamel Z., Krupalnik V., Zerbib M., Geula S., Caspi I., Schneir D., Shwartz T., Gilad S., Amann Zalcenstein D., Benjamin S., Amit I., Tanay A., Massarwa R., Novershtern N. & Hanna J. (. (2013), Nature. 504, 7479, p. 282-286

  • Generation of topically transgenic rats by in utero electroporation and in vivo bioluminescence screening.

    Authors: Vomund S., Sapir T., Reiner O., Silva M. A. S. & Korth C. (2013), Journal of visualized experiments : JoVE. 79, p. e50146

  • One load to rule them all: Mechanical control of the musculoskeletal system in development and aging

    Authors: Shwartz Y., Blitz E. & Zelzer E. (2013), Differentiation. 86, 3, p. 104-111

  • Oct4 shuffles Sox partners to direct cell fate

    Authors: Mansour A. A. & Hanna J. H. (2013), EMBO Journal. 32, 7, p. 917-919

  • The Expression of the Beta Cell-Derived Autoimmune Ligand for the Killer Receptor Nkp46 Is Attenuated in Type 2 Diabetes

    Authors: Gur C., Enk J., Weitman E., Bachar E., Suissa Y., Cohen G., Schyr R. B., Sabanay H., Horwitz E., Glaser B., Dor Y., Pribluda A., Hanna J. H., Leibowitz G. & Mandelboim O. (2013), PLoS ONE. 8, 8, e74033

  • Runx3-mediated transcriptional program in cytotoxic lymphocytes

    Authors: Lotem J., Levanon D., Negreanu V., Leshkowitz D., Friedlander G. & Groner Y. (2013), PLoS ONE. 8, 11, e80467

  • A temporary decrease in mineral density in perinatal mouse long bones

    Authors: Sharir A., Milgram J., Dubnov-Raz G., Zelzer E. & Shahar R. (2013), Bone. 52, 1, p. 197-205

  • Microtubule dynamics alter the interphase nucleus

    Authors: Gerlitz G., Reiner O. & Bustin M. (2013), Cellular and Molecular Life Sciences. 70, 7, p. 1255-1268

  • Tendon-bone attachment unit is formed modularly by a distinct pool of Scx-and Sox9-positive progenitors

    Authors: Blitz E., Sharir A., Akiyama H. & Zelzer E. (2013), Development (Cambridge). 140, 13, p. 2680-2690

  • LIS1 functions in normal development and disease

    Authors: Reiner O. & Sapir T. (2013), Current Opinion in Neurobiology. 23, 6, p. 951-956

  • Oriented covalent immobilization of antibodies for measurement of intermolecular binding forces between zipper-like contact surfaces of split inteins

    Authors: Sorci M., Dassa B., Liu H., Anand G., Dutta A. K., Pietrokovski S., Belfort M. & Belfort G. (2013), Analytical Chemistry. 85, 12, p. 6080-6088

  • Deterministic direct reprogramming of somatic cells to pluripotency

    Authors: Rais Y., Zviran A., Geula S., Gafni O., Chomsky E., Viukov S., Mansour A. A., Caspi I., Krupalnik V., Zerbib M., Maza I., Mor N., Baran D., Weinberger L., Jaitin D. A., Lara Astiaso A. D., Blecher-Gonen R., Shipony Z., Mukamel Z., Hagai T., Gilad S., Amann Zalcenstein D., Tanay A., Amit I., Novershtern N. & Hanna J. (. (2013), Nature. 502, 7469, p. 65-70

  • By their genes ye shall know them: Genomic signatures of predatory bacteria

    Authors: Pasternak Z., Pietrokovski S., Rotem O., Gophna U., Lurie-Weinberger M. N. & Jurkevitch E. (2013), ISME Journal. 7, 4, p. 756-769

  • Addiction of t(8;21) and inv(16) Acute Myeloid Leukemia to Native RUNX1

    Authors: Ben Ami A. O., Friedman D., Leshkowitz D., Goldenberg D., Orlovsky K., Pencovich N., Lotem J., Tanay A. & Groner Y. (2013), Cell Reports. 4, 6, p. 1131-1143

  • Shootin1 Acts in Concert with KIF20B to Promote Polarization of Migrating Neurons

    Authors: Sapir T., Levy T., Sakakibara A., Rabinkov A., Miyata T. & Reiner O. (2013), Journal of Neuroscience. 33, 29, p. 11932-11948

  • Transcriptional Reprogramming of CD11b+Esamhi Dendritic Cell Identity and Function by Loss of Runx3

    Authors: Dicken J., Mildner A., Leshkowitz D., Touw I. P., Hantisteanu S., Groner Y. & Jung S. (2013), PLoS ONE. 8, 10, e77490

  • Cell-Autonomous Function of Runx1 Transcriptionally Regulates Mouse Megakaryocytic Maturation

    Authors: Pencovich N., Jaschek R., Dicken J., Amit A., Lotem J., Tanay A. & Groner Y. (2013), PLoS ONE. 8, 5, e64248

  • Involvement of parental imprinting in the antisense regulation of onco-miR-372-373

    Authors: Stelzer Y., Sagi I. & Benvenisty N. (2013), Nature Communications. 4, 2724

  • Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

    Authors: Yona S., Kim K., Wolf Y., Mildner A., Varol D., Breker M., Strauss-Ayali D., Viukov S., Guilliams M., Misharin A., Hume D. A., Perlman H., Malissen B., Zelzer E. & Jung S. (2013), Immunity. 38, 1, p. 79-91

  • RNF20 and USP44 Regulate Stem Cell Differentiation by Modulating H2B Monoubiquitylation

    Authors: Fuchs G., Shema E., Vesterman R., Kotler E., Wolchinsky Z., Wilder S., Golomb L., Pribluda A., Zhang F., Haj-Yahya M., Feldmesser E., Brik A., Yu X., Hanna J., Aberdam D., Domany E. & Oren M. (2012), Molecular Cell. 46, 5, p. 662-673

  • Tracing the genesis of human embryonic stem cells

    Authors: Pribluda A. & Hanna J. H. (2012),

  • The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a down syndrome mouse model

    Authors: Raveau M., Lignon J. M., Nalesso V., Duchon A., Groner Y., Sharp A. J., Dembele D., Brault V. & Hérault Y. (2012), PLoS Genetics. 8, 5, e1002724

  • Protein Tyrosine Phosphatase Epsilon (PTPe)

    Authors: Elson A. & Rousso Noori L. (2012),

  • Roles of VWRPY motif-mediated gene repression by Runx proteins during T-cell development

    Authors: Seo W., Tanaka H., Miyamoto C., Levanon D., Groner Y. & Taniuchi I. (2012), Immunology and Cell Biology. 90, 8, p. 827-830

  • Clonal allelic predetermination of immunoglobulin-kappa rearrangement

    Authors: Farago M., Rosenbluh C., Tevlin M., Fraenkel S., Schlesinger S., Masika H., Gouzman M., Teng G., Schatz D., Rais Y., Hanna J. H., Mildner A., Jung S., Mostoslavsky G., Cedar H. & Bergman Y. (2012), Nature. 490, 7421, p. 561-+

  • The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming

    Authors: Mansour A. A., Gafni O., Weinberger L., Zviran A., Ayyash M., Rais Y., Krupalnik V., Zerbib M., Amann Zalcenstein D., Maza I., Geula S., Viukov S., Holtzman L., Pribluda A., Canaani E., Horn-Saban S., Amit I., Novershtern N. & Hanna J. H. (2012), Nature. 488, 7411, p. 409-413

  • Muscle contraction controls skeletal morphogenesis through regulation of chondrocyte convergent extension

    Authors: Shwartz Y., Farkas Z., Stern T., Aszódi A. & Zelzer E. (2012), Developmental Biology. 370, 1, p. 154-163

  • Epidermal growth factor receptor (EGFR)-mediated positive feedback of protein-tyrosine phosphatase ε (PTPε) on ERK1/2 and AKT protein pathways is required for survival of human breast cancer cells

    Authors: Nunes-Xavier C. E., Elson A. & Pulido R. (2012), Journal of Biological Chemistry. 287, 5, p. 3433-3444

  • Interkinetic nuclear movement in the ventricular zone of the cortex

    Authors: Reiner O., Sapir T. & Gerlitz G. (2012), Journal of Molecular Neuroscience. 46, 3, p. 516-526

  • HIF1α is a central regulator of collagen hydroxylation and secretion under hypoxia during bone development

    Authors: Bentovim L., Amarilio R. & Zelzer E. (2012), Development (Cambridge). 139, 23, p. 4473-4483

  • Expression profiling during mammary epithelial cell three-dimensional morphogenesis identifies PTPRO as a novel regulator of morphogenesis and ErbB2-mediated transformation

    Authors: Yu M., Lin G., Arshadi N., Kalatskaya I., Xue B., Haider S., Nguyen F., Boutros P. C., Elson A., Muthuswamy L. B., Tonks N. K. & Muthuswamy S. K. (2012), Molecular and Cellular Biology. 32, 19, p. 3913-3924

  • The role of the complement pathway in neuronal migration in the developing brain

    Authors: Gorelik A. & Reiner O. (2012),

  • Positional differences of axon growth rates between sensory neurons encoded by runx3

    Authors: Lallemend F., Sterzenbach U., Hadjab-Lallemend S., Aquino J. B., Castelo-Branco G., Sinha I., Villaescusa J. C., Levanon D., Wang Y., Franck M. C., Kharchenko O., Adameyko I., Linnarsson S., Groner Y., Turner E. & Ernfors P. (2012), EMBO Journal. 31, 18, p. 3718-3729

  • S1P1 inhibits sprouting angiogenesis during vascular development

    Authors: Ben Shoham S. A., Malkinson G., Krief S., Shwartz Y., Ely Y., Ferrara N., Yaniv K. & Zelzer E. (2012), Development (Cambridge). 139, 20, p. 3859-3869

  • Multifaceted modulation of K + channels by protein-tyrosine phosphatase ε tunes neuronal excitability

    Authors: Ebner-Bennatan S., Patrich E., Peretz A., Kornilov P., Tiran Z., Elson A. & Attali B. (2012), Journal of Biological Chemistry. 287, 33, p. 27614-27628

  • MARK2/Par-1 guides the directionality of neuroblasts migrating to the olfactory bulb

    Authors: Mejia-Gervacio S., Murray K., Sapir T., Belvindrah R., Reiner O. & Lledo P. M. (2012), Molecular and Cellular Neuroscience. 49, 2, p. 97-103

  • Author reply to: RUNX3 is expressed in the epithelium of the gastrointestinal tract

    Authors: Levanon D., Negreanu V., Lotem J. & Groner Y. (2012),

  • Ndel1-derived peptides modulate bidirectional transport of injected beads in the squid giant axon

    Authors: Segal M., Soifer I., Petzold H., Howard J., Elbaum M. & Reiner O. (2012), Biology Open. 1, 3, p. 220-231

  • Tau's role in the developing brain: Implications for intellectual disability

    Authors: Sapir T., Frotscher M., Levy T., Mandelkow E. & Reiner O. (2012), Human Molecular Genetics. 21, 8, p. 1681-1692, ddr603

  • Loss of PAFAH1B2 reduces amyloid-β generation by promoting the degradation of amyloid precursor protein C-terminal fragments

    Authors: Page R. M., Münch A., Horn T., Kuhn P. H., Colombo A., Reiner O., Boutros M., Steiner H., Lichtenthaler S. F. & Haass C. (2012), Journal of Neuroscience. 32, 50, p. 18204-18214

  • The heart endocardium is derived from vascular endothelial progenitors

    Authors: Milgrom-Hoffman M., Harrelson Z., Ferrara N., Zelzer E., Evans S. M. & Tzahor E. (2011), Development. 138, 21, p. 4777-4787

  • Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells

    Authors: Carey B. W., Markoulaki S., Hanna J. H., Faddah D. A., Buganim Y., Kim J., Ganz K., Steine E. J., Cassady J. P., Creyghton M. P., Welstead G. G., Gao Q. & Jaenisch R. (2011), Cell Stem Cell. 9, 6, p. 588-598

  • EsBAF safeguards Stat3 binding to maintain pluripotency

    Authors: Novershtern N. & Hanna J. H. (2011), Nature Cell Biology. 13, 8, p. 886-888

  • New modularity of DAP-kinases: Alternative splicing of the DRP-1 gene produces a Zipk-like isoform

    Authors: Shoval Y., Berissi H., Kimchi A. & Pietrokovski S. (2011), PLoS ONE. 6, 3, e17344

  • Absence of Runx3 expression in normal gastrointestinal epithelium calls into question its tumour suppressor function

    Authors: Levanon D., Bernstein Y., Negreanu V., Bone K. R., Pozner A., Eilam R., Lotem J., Brenner O. & Groner Y. (2011), EMBO Molecular Medicine. 3, 10, p. 593-604

  • Regulatory interactions among musculoskeletal tissues during embryonic development

    Authors: Zelzer E. (2011),

  • Muscle force regulates bone shaping for optimal loadbearing capacity during embryogenesis

    Authors: Sharir A., Stern T., Rot C., Shahar R. & Zelzer E. (2011), Development. 138, 15, p. 3247-3259

  • Protein tyrosine phosphatase epsilon affects body weight by downregulating leptin signaling in a phosphorylation-dependent manner

    Authors: Rousso Noori N. L., Knobler H., Levy-Apter E., Kuperman Y., Neufeld - Cohen -. C. A., Keshet Y., Akepati V. R., Klinghoffer R. A., Chen A. & Elson A. (2011), Cell Metabolism. 13, 5, p. 562-572

  • Myosin drives autophagy in a pathway linking Atg1 to Atg9

    Authors: Bialik S., Pietrokovski S. & Kimchi A. (2011), EMBO Journal. 30, 4, p. 629-630

  • Linking cytoplasmic dynein and transport of Rab8 vesicles to the midbody during cytokinesis by the doublecortin domain-containing 5 protein

    Authors: Kaplan A. & Reiner O. (2011), Journal of Cell Science. 124, 23, p. 3989-4000

  • Activity, specificity and structure of I-Bth0305I: A representative of a new homing endonuclease family

    Authors: Taylor G. K., Heiter D. F., Pietrokovski S. & Stoddard B. L. (2011), Nucleic Acids Research. 39, 22, p. 9705-9719

  • Tendon homeostasis: The right pull

    Authors: Sharir A. & Zelzer E. (2011),

  • Identification of plant RAD52 homologs and characterization of the arabidopsis thaliana RAD52-like genes

    Authors: Samach A., Melamed-Bessudo C., Avivi-Ragolski N., Pietrokovski S. & Levy A. (2011), Plant Cell. 23, 12, p. 4266-4279

  • Global analysis of parental imprinting in human parthenogenetic induced pluripotent stem cells

    Authors: Stelzer Y., Yanuka O. & Benvenisty N. (2011), Nature Structural and Molecular Biology. 18, 6, p. 735-741

  • Atg8: An autophagy-related ubiquitin-like protein family

    Authors: Shpilka T., Weidberg H., Pietrokovski S. & Elazar Z. (2011), GENOME BIOLOGY. 12, 7, 226

  • Distinct molecular regulation of glycogen synthase kinase-3α isozyme controlled by its N-terminal region functional role in CALCIUM/CALPAIN signaling

    Authors: Azoulay-Alfaguter I., Yaffe Y., Licht-Murava A., Urbanska M., Jaworsk J., Pietrokovski S., Hirschberg K. & Eldar-Finkelman H. (2011), Journal of Biological Chemistry. 286, 15, p. 13470-13480

  • A Runx1-Smad6 rheostat controls Runx1 activity during embryonic hematopoiesis

    Authors: Knezevic K., Bee T., Wilson N. K., Janes M. E., Kinston S., Polderdijk S., Kolb-Kokocinski A., Ottersbach K., Pencovich N., Groner Y., de Bruijn B. M., Goettgens B. & Pimanda J. E. (2011), Molecular and Cellular Biology. 31, 14, p. 2817-2826

  • Selective loss of glycogen synthase kinase-3α in birds reveals distinct roles for GSK-3 isozymes in tau phosphorylation

    Authors: Alon L. T., Pietrokovski S., Barkan S., Avrahami L., Kaidanovich-Beilin O., Woodgett J. R., Barnea A. & Eldar-Finkelman H. (2011), FEBS Letters. 585, 8, p. 1158-1162

  • Bone mineralization proceeds through intracellular calcium phosphate loaded vesicles: A cryo-electron microscopy study

    Authors: Mahamid J., Sharir A., Gur D., Zelzer E., Addadi L. & Weiner S. (2011), Journal of Structural Biology. 174, 3, p. 527-535

  • ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer

    Authors: Thoms J. A., Birger Y., Foster S., Knezevic K., Kirschenbaum Y., Chandrakanthan V., Jonquieres G., Spensberger D., Wong J. W., Oram S. H., Kinston S. J., Groner Y., Lock R., MacKenzie K. L., Göttgens B., Izraeli S. & Pimanda J. E. (2011), Blood. 117, 26, p. 7079-7089

  • Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex

    Authors: Yamasaki T., Kawasaki H., Arakawa S., Shimizu K., Shimizu S., Reiner O., Okano H., Nishina S., Azuma N., Penninger J. M., Katada T. & Nishina H. (2011), Journal of Neuroscience. 31, 46, p. 16872-16883

  • Omics Data Management and Annotation

    Authors: Harel A., Dalah I., Pietrokovski S., Safran M. & Lancet D. (2011), Bioinformatics For Omics Data. p. 71-96

  • Induced Pluripotent Stem Cells: Their Role in Modeling Disease and Regenerative Medicine

    Authors: Stelzer Y. & Pick M. (2011), Stem Cell-Based Tissue Repair. p. 117-140

  • Dynamic combinatorial interactions of RUNX1 and cooperating partners regulates megakaryocytic differentiation in cell line models

    Authors: Pencovich N., Jaschek R., Tanay A. & Groner Y. (2011), Blood. 117, 1, p. 1-14

  • The STATs on naive iPSC reprogramming

    Authors: Hanna J. H. (2010),

  • Translation regulation of Runx3

    Authors: Bone K. R., Gruper Y., Goldenberg D., Levanon D. & Groner Y. (2010), Blood Cells Molecules And Diseases. 45, 2, p. 112-116

  • PAF-AH catalytic subunits modulate the wnt pathway in developing gabaergic neurons

    Authors: Livnat I., Finkelshtein D., Ghosh I., Arai H. & Reiner O. (2010), FRONTIERS IN CELLULAR NEUROSCIENCE. 4, MAY, 19

  • Substrate Competitive GSK-3 Inhibitors {single bond} strategy and Implications

    Authors: Eldar-Finkelman H., Licht-Murava A., Pietrokovski S. & Eisenstein M. (2010), Biochimica Et Biophysica Acta-Proteins And Proteomics. 1804, 3, p. 598-603

  • In vivo effects of APP are not exacerbated by BACE2 co-overexpression: Behavioural characterization of a double transgenic mouse model

    Authors: Azkona G., Levannon D., Groner Y. & Dierssen M. (2010), Amino Acids. 39, 5, p. 1571-1580

  • Connecting muscles to tendons: Tendons and musculoskeletal development in flies and vertebrates

    Authors: Schweitzer R., Zelzer E. & Volk T. (2010), Development. 137, 17, p. 2807-2817

  • The influence of severe prolonged exercise restriction on the mechanical and structural properties of bone in an avian model

    Authors: Shipov A., Sharir A., Zelzer E., Milgram J., Monsonego-Ornan E. & Shahar R. (2010), Veterinary Journal. 183, 2, p. 153-160

  • Bone ridge patterning during musculoskeletal assembly is mediated through SCX regulation of Bmp4 at the tendon-skeleton junction

    Authors: Zelzer E. & Blitz E. (2010),

  • Connecting muscles to tendons: Tendons and musculoskeletal development in flies and vertebrates (Development 137 (2807-2817))

    Authors: Schweitzer R., Zelzer E. & Volk T. (2010),

  • Ndel1 palmitoylation: A new mean to regulate cytoplasmic dynein activity

    Authors: Shmueli A., Segal M., Sapir T., Tsutsumi R., Noritake J., Bar A., Sapoznik S., Fukata Y., Orr I., Fukata M. & Reiner O. (2010), EMBO Journal. 29, 1, p. 107-119

  • Bone vascularization and trabecular bone formation are mediated by PKBalpha/Akt1 in a gene-dosage-dependent manner: In vivo and ex vivo MRI

    Authors: Vandoorne K., Magland J., Plaks V., Sharir A., Zelzer E., Wehrli F., Hemmings B. A., Harmelin A. & Neeman M. (2010), Magnetic Resonance in Medicine. 64, 1, p. 54-64

  • Meig1 deficiency causes a severe defect in mouse spermatogenesis

    Authors: Salzberg Y., Eldar T., Karminsky O. D., Itach S. B. S., Pietrokovski S. & Don J. (2010), Developmental Biology. 338, 2, p. 158-167

  • A JIP3-regulated GSK3β/DCX signaling pathway restricts axon branching

    Authors: Bilimoria P. M., De La Torre-Ubieta L., Ikeuchi Y., Becker E. B., Reiner O. & Bonni A. (2010), Journal of Neuroscience. 30, 50, p. 16766-16776

  • The novel RUNX3/p33 isoform is induced upon monocyte-derived dendritic cell maturation and downregulates IL-8 expression

    Authors: Puig-Kroeger A., Aguilera-Montilla N., Martinez-Nunez R., Dominguez-Soto A., Sanchez-Cabo F., Martin-Gayo E., Zaballos A., Toribio M. L., Groner Y., Ito Y., Dopazo A., Corcuera M. T., Alonso Martin M. M. J., Vega M. A. & Corbi A. L. (2010), Immunobiology. 215, 9-10, p. 812-820

  • Mutation detection with next-generation resequencing through a mediator genome

    Authors: Wurtzel O., Dori-Bachash M., Pietrokovski S., Jurkevitch E. & Sorek R. (2010), PLoS ONE. 5, 12, e15628

  • Pluripotency and cellular reprogramming: Facts, hypotheses, unresolved issues

    Authors: Hanna J. H., Saha K. & Jaenisch R. (2010), Cell. 143, 4, p. 508-525

  • Splicing of the mycobacteriophage bethlehem DnaB intein: Identification of a new mechanistic class of inteins that contain an obligate block f nucleophile

    Authors: Tori K., Dassa B., Johnson M. A., Southworth M. W., Brace L. E., Ishino Y., Pietrokovski S. & Perler F. B. (2010), Journal of Biological Chemistry. 285, 4, p. 2515-2526