
-
In Synergy: Optimizing CAR T Development and Personalizing Patient Care Using Single-Cell Technologies
-
A non-antibiotic-disrupted gut microbiome is associated with clinical responses to CD19-CAR-T cell cancer immunotherapy
-
Insights into the co-evolution of epithelial cells and fibroblasts in the esophageal tumor microenvironment
-
Actin Filaments Couple thes Protrusive Tips to the Nucleus through the I‐BAR Domain Protein IRSp53 during the Migration of Cells on 1D Fibers
-
Characterisation of knowledge of cancer, illness perceptions and their interaction among high-school students
-
Spatial profiling technologies illuminate the tumor microenvironment
-
Distinct spatiotemporal features of microglia and monocyte-derived macrophages in glioma
-
Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture
-
Large-Scale Immuno-Peptidome Analysis Reveals Recurrent Post-Translational Splicing of Cancer and Immune-Associated Genes
-
Arterial Thromboembolism in Patients With AF and CHA2DS2-VASc Score 0-2 With and Without Cancer
-
Probing lipids relaxation times in breast cancer using magnetic resonance spectroscopic fingerprinting
-
MYC induces immunotherapy and interferon-γ resistance through downregulation of JAK2
-
Mutually communicated model based on multi-parametric MRI for automated segmentation and classification of prostate cancer
-
Targeted delivery of tumor necrosis factor in combination with CCNU induces a T cell-dependent regression of glioblastoma
-
The microbial genotoxin colibactin exacerbates mismatch repair mutations in colorectal tumors
-
EMSY stabilization in KEAP1-mutant lung cancer disrupts genome stability and type I interferon signaling
-
It takes two to tango: the role of tumor-associated macrophages in T cell-directed immune checkpoint blockade therapy
-
Cerebrospinal fluid proteomics indicates immune dysregulation and neuronal dysfunction in antibody associated autoimmune encephalitis
-
Spectrum of Response to Platinum and PARP Inhibitors in Germline BRCA–Associated Pancreatic Cancer in the Clinical and Preclinical Setting
-
Multiplexed, single-molecule, epigenetic analysis of plasma-isolated nucleosomes for cancer diagnostics
-
CAR-T Cell Therapy and the Gut Microbiota
-
The landscape of T cell antigens for cancer immunotherapy
-
Cellular states are coupled to genomic and viral heterogeneity in HPV-related oropharyngeal carcinoma
-
Immunometabolism at the crossroads of obesity and cancer—a Keystone Symposia report
-
Functional Impact of Protein-RNA Variation in Clinical Cancer Analyses
-
Depleting the 19S proteasome regulatory PSMD1 subunit as a cancer therapy strategy
-
Folylpolyglutamate synthetase mRNA G-quadruplexes regulate its cell protrusion localization and enhance a cancer cell invasive phenotype upon folate repletion
-
UV irradiation remodels the specificity landscape of transcription factors
-
A natural goldmine of binding proteins and soluble receptors simplified their translation to blockbuster drugs, all in one decade
-
Fungi and cancer
-
The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC
-
FcyRIIB is a novel immune checkpoint in the tumor microenvironment limiting activity of Treg-targeting antibodies
-
Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy
-
Computational design of BclxL inhibitors that target transmembrane domain interactions
-
A single-molecule liquid biopsy for cancer diagnosis
-
Tackling tumor complexity with single-cell proteomics
-
Early Infiltration of Innate Immune Cells to the Liver Depletes HNF4α and Promotes Extrahepatic Carcinogenesis
-
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis
-
The C-terminal tail of CSNAP attenuates the CSN complex
-
Integrative study of whole exome variation and expression in gingivo-buccal oral squamous cell carcinoma revealed alteration in TLR-activated MAP-Kinase signalling
-
TRAF3 suppression encourages B cell recruitment and prolongs survival of microbiome-intact mice with ovarian cancer
-
Trapping all ERBB ligands decreases pancreatic lesions in a murine model of pancreatic ductal adenocarcinoma
-
Insights into the co-evolution of epithelial cells and fibroblasts in the esophageal tumor microenvironment
-
From gatekeepers to providers: regulation of immune functions by cancer-associated fibroblasts
-
Association between diabetes mellitus and reduced efficacy of pembrolizumab in non–small cell lung cancer
-
The proteasome regulator PSME4 drives immune evasion and abrogates anti-tumor immunity in NSCLC
-
Modulating the proliferative and cytotoxic properties of patient-derived TIL by a synthetic immune niche of immobilized CCL21 and ICAM1
-
Impact of TP53 Genomic Alterations in Large B-Cell Lymphoma Treated With CD19-Chimeric Antigen Receptor T-Cell Therapy
-
Cancer and cell cycle
-
Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression
-
PRC2-indepdendent actions of H3.3K27M in embryonic stem cell differentiation
-
Bispecific antibodies increase the therapeutic window of CD40 agonists through selective dendritic cell targeting
-
Next Generation CD40 Agonistic Antibodies for Cancer Immunotherapy
-
ICAM-1 on Breast Cancer Cells Suppresses Lung Metastasis but Is Dispensable for Tumor Growth and Killing by Cytotoxic T Cells
-
Anti-CTLA-4 antibodies drive myeloid activation and reprogram the tumor microenvironment through Fc gamma R engagement and type I interferon signaling
-
Cancer microbiome
-
Tumor-reactive antibodies evolve from non-binding and autoreactive precursors
-
Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans
-
A new function for the serine protease HtrA2 in controlling radiation-induced senescence in cancer cells
-
Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis
-
DestVI identifies continuums of cell types in spatial transcriptomics data
-
Targeted Drug Delivery for the Treatment of Blood Cancers
-
Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors
-
Breast cancer plasticity is restricted by a LATS1-NCOR1 repressive axis
-
Pseudo-mutant P53 is a unique phenotype of DNMT3A -mutated pre-leukemia
-
Proteomic signature for detection of high-grade ovarian cancer in germline BRCA mutation carriers
-
BREAst Cancer Personalised NuTrition (BREACPNT): dietary intervention in breast cancer survivors treated with endocrine therapy – a protocol for a randomised clinical trial
-
Aptamer-Modified Au Nanoparticles: Functional Nanozyme Bioreactors for Cascaded Catalysis and Catalysts for Chemodynamic Treatment of Cancer Cells
-
Mechanisms of immune activation and regulation: lessons from melanoma
-
Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions
-
ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells
-
The industrial genomic revolution: A new era in neuroimmunology
-
NRas activity is regulated by dynamic interactions with nanoscale signaling clusters at the plasma membrane
-
Comparing Intraperitoneal and Intravenous Personalized ErbB2CAR-T for the Treatment of Epithelial Ovarian Cancer
-
Pediatric glioblastoma cells are sensitive to drugs that inhibit eIF2α dephosphorylation and its phosphomimetic S51D variant
-
Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression
-
Small molecule inhibitor of Igf2bp1 represses Kras and a pro-oncogenic phenotype in cancer cells
-
De novo-designed transmembrane domains tune engineered receptor functions
-
DNA methylation landscape of tumor-associated macrophages reveals pathways, transcription factors, and prognostic value relevant to triple-negative breast cancer patients
-
Downregulation of the Tumor Suppressor TFF1 Is Required during Induction of Colon Cancer Progression by L1
-
Di-genic inheritance of germline POLE and PMS2 pathogenic variants causes a unique condition associated with pediatric cancer predisposition
-
IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells
-
Dependence of ABCB1 transporter expression and function on distinct sphingolipids generated by ceramide synthases-2 and -6 in chemoresistant renal cancer
-
Ex vivo organotypic cultures for synergistic therapy prioritization identify patient-specific responses to combined MEK and Src inhibition in colorectal cancer
-
Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution
-
Polyclonal antibody-induced downregulation of HER1/EGFR and HER2 surpasses the effect of combinations of specific registered antibodies
-
H3-K27M-mutant nucleosomes interact with MLL1 to shape the glioma epigenetic landscape
-
Compartmentalization of the host microbiome: how tumor microbiota shapes checkpoint immunotherapy outcome and offers therapeutic prospects
-
Stochastic transitions as a major source of cancer heterogeneity
-
Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions
-
A coalition to heal—the impact of the cardiac microenvironment
-
Cancer-associated fibroblasts in the single-cell era
-
CD74 as a regulator of transcription in normal B cells
-
An exercise-induced metabolic shield in distant organs blocks cancer progression and metastatic dissemination
-
It's all in the combination: decoding the epigenome for cancer research and diagnostics
-
Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas
-
Cardiovascular Disease Among Patients With AML and CHIP-Related Mutations
-
Immunogenicity and safety of BNT162b2 mRNA vaccine booster in actively treated patients with cancer
-
Aptamer-Functionalized Ce4+-Ion-Modified C-Dots: Peroxidase Mimicking Aptananozymes for the Oxidation of Dopamine and Cytotoxic Effects toward Cancer Cells
-
On the development of a neoantigen vaccine for the prevention of Lynch Syndrome
-
The brain-immune ecosystem: Implications for immunotherapy in defeating neurodegenerative diseases
-
5’isomiR-183-5p|+2 elicits tumor suppressor activity in a negative feedback loop with E2F1
-
Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins
-
BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling
-
The interaction of CD4 + helper T cells with dendritic cells shapes the tumor microenvironment and immune checkpoint blockade response
-
Global DNA Methylation Analysis of Cancer-Associated Fibroblasts Reveals Extensive Epigenetic Rewiring Linked with RUNX1 Upregulation in Breast Cancer Stroma
-
SmMIP-tools: a computational toolset for processing and analysis of single-molecule molecular inversion probes derived data
-
Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism
-
Controls for Phylogeny and Robust Analysis in Pareto Task Inference
-
Cellular and metabolic characteristics of pre-leukemic hematopoietic progenitors with GATA2 haploinsuficiency
-
An activation to memory differentiation trajectory of tumor-infiltrating lymphocytes informs metastatic melanoma outcomes
-
Anti-SARS-CoV-2 immunoadhesin remains effective against Omicron and other emerging variants of concern
-
Divergence of mutational signatures in association with breast cancer subtype
-
A Functional Pre-Screening Platform for Identifying Points of Vulnerability in the Cell Death Map of Human Melanoma Tumors
-
Cytoplasmic forces functionally reorganize nuclear condensates in oocytes
-
Interactive, integrated analysis of single-cell transcriptomic and phylogenetic data with PhyloVision
-
The magnitude of LFA-1/ICAM-1 forces fine-tune TCR-triggered T cell activation
-
Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients
-
Visual barcodes for clonal-multiplexing of live microscopy-based assays
-
Early antitumor activity of oral Langerhans cells is compromised by a carcinogen
-
Nine receptors and binding proteins, four drugs, and one woman: Historical and personal perspectives
-
Genetic insight into Birt–Hogg–Dubé syndrome in Indian patients reveals novel mutations at FLCN
-
Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma
-
DOP53 In-depth characterisation of the serum antibody epitope repertoire in Inflammatory Bowel Disease by high-throughput phage-displayed immunoprecipitation sequencing
-
CXCR4 and CD74 together enhance cell survival in response to macrophage migration-inhibitory factor in chronic lymphocytic leukemia
-
AXL and error-prone DNA replication confer drug resistance and offer strategies to treat EGFR-mutant lung cancer
-
Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis
-
Blockade of the protease ADAM17 ameliorates experimental pancreatitis
-
Brain metastases: Not all tumors are created equal
-
Sex Biases in Cancer and Autoimmune Disease Incidence Are Strongly Positively Correlated with Mitochondrial Gene Expression across Human Tissues
-
Drugging p53 in cancer: one protein, many targets
-
Mitochondrial ROS drive resistance to chemotherapy and immune-killing in hypoxic non-small cell lung cancer
-
Polysome-CAGE of TCL1-driven chronic lymphocytic leukemia revealed multiple N-terminally altered epigenetic regulators and a translation stress signature
-
S6K1 phosphorylates Cdk1 and MSH6 to regulate DNA repair
-
Post-translational modifications reshape the antigenic landscape of the MHC I immunopeptidome in tumors
-
Spatial organization and early signaling of the B-cell receptor in CLL
-
Mouse Modeling Dissecting Macrophage–Breast Cancer Communication Uncovered Roles of PYK2 in Macrophage Recruitment and Breast Tumorigenesis
-
Intratumor heterogeneity and anti-tumor immunity shape one another bidirectionally
-
The microbiome and human cancer
-
Single Instillation of Hypertonic Saline Immediately Following Transurethral Resection of Bladder Tumor for Recurrence Prevention –A Phase I Study
-
Albumin-EDTA-Vanadium Is a Powerful Anti-Proliferative Agent, Following Entrance into Glioma Cells via Caveolae-Mediated Endocytosis
-
Identification of variable stages in murine pancreatic tumors by a multiparametric approach employing hyperpolarized 13C MRSI, 1H diffusivity and 1H T1 MRI
-
Improving deuterium metabolic imaging (DMI) signal‐to‐noise ratio by spectroscopic multi‐echo bSSFP: A pancreatic cancer investigation
-
TP53 missense mutations in PDAC are associated with enhanced fibrosis and an immunosuppressive microenvironment
-
Conformational switches and redox properties of the colon cancer‐associated human lectin ZG16
-
Decoding Cancer Biology One Cell at a Time
-
Learned Super Resolution Ultrasound for Improved Breast Lesion Characterization
-
Melanoma models for the next generation of therapies
-
Spatially organized multicellular immune hubs in human colorectal cancer
-
Breast cancer is marked by specific, Public T-cell receptor CDR3 regions shared by mice and humans
-
Identification of bacteria-derived HLA-bound peptides in melanoma
-
CD84 is a regulator of the immunosuppressive microenvironment in multiple myeloma
-
Chromothripsis drives the evolution of gene amplification in cancer
-
Persistent Inflammatory Stimulation Drives the Conversion of MSCs to Inflammatory CAFs That Promote Pro-Metastatic Characteristics in Breast Cancer Cells
-
Proteomic Profiling of Tissue Exosomes Indicates Continuous Release of Malignant Exosomes in Urinary Bladder Cancer Patients, Even with Pathologically Undetectable Tumour
-
P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression
-
The extracellular matrix protein agrin is essential for epicardial epithelial-to-mesenchymal transition during heart development
-
CYP46A1-APOE axis at the choroid plexus is compromised in Alzheimer's disease but is amenable to rescue
-
Alternative Splicing of the Inhibitory Immune Checkpoint Receptor SLAMF6 Generates a Dominant Positive Form, Boosting T-cell Effector Functions
-
Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles
-
The context-specific roles of urea cycle enzymes in tumorigenesis
-
A Necessary Role for Increased Biglycan Expression during L1-Mediated Colon Cancer Progression
-
Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma
-
Diffusion Is Directional: Innovative Diffusion Tensor Imaging to Improve Prostate Cancer Detection
-
Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies
-
The prospects of tumor chemosensitivity testing at the single-cell level
-
Multiplexed Imaging Analysis of the Tumor-Immune Microenvironment Reveals Predictors of Outcome in Triple-Negative Breast Cancer
-
TENT4A Non-Canonical Poly(A) Polymerase Regulates DNA-Damage Tolerance via Multiple Pathways That Are Mutated in Endometrial Cancer
-
Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models
-
Anti-tumour immunity induces aberrant peptide presentation in melanoma
-
Efficient acquisition of tens of thousands of short tandem repeats in single-cell whole-genome-amplified DNA
-
Coordinated regulation of WNT/β-catenin, c-Met, and integrin signalling pathways by miR-193b controls triple negative breast cancer metastatic traits
-
Clump sequencing exposes the spatial expression programs of intestinal secretory cells
-
Proteomic patterns associated with response to breast cancer neoadjuvant treatment
-
Reduced Lamin A/C Does Not Facilitate Cancer Cell Transendothelial Migration but Compromises Lung Metastasis
-
Targeting nucleotide metabolism as the nexus of viral infections, cancer, and the immune response
-
Immunotherapy for Triple-Negative Breast Cancer
-
Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis
-
Evolution of fibroblasts in the lung metastatic microenvironment is driven by stage-specific transcriptional plasticity
-
The key roles of cancer stem cell-derived extracellular vesicles
-
EGFR in Cancer: Signaling Mechanisms, Drugs, and Acquired Resistance
-
Conformation-Specific Inhibitory Anti-MMP-7 Monoclonal Antibody Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Chemotherapeutic Cell Kill
-
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
-
Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo
-
Clinical Proteomics of Metastatic Melanoma Reveals Profiles of Organ Specificity and Treatment Resistance
-
Biological and therapeutic implications of a unique subtype of NPM1 mutated AML
-
Interacting evolutionary pressures drive mutation dynamics and health outcomes in aging blood
-
Roles for growth factors and mutations in metastatic dissemination
-
A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma
-
Using a Recently Approved Tumor Mutational Burden Biomarker to Stratify Patients for Immunotherapy May Introduce a Sex Bias
-
The evolution of leukaemia from pre‐leukaemic and leukaemic stem cells
-
Tumour inflammation signature and expression of S100A12 and HLA class I improve survival in HPV-negative hypopharyngeal cancer
-
MT1 and MT2 melatonin receptors play opposite roles in brain cancer progression
-
Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis
-
NASH limits anti-tumour surveillance in immunotherapy-treated HCC
-
Combined presentation and immunogenicity analysis reveals a recurrent RAS.Q61K neoantigen in melanoma
-
LFA-1 in T cell priming, differentiation, and effector functions
-
Cancer-associated fibroblasts promote aggressive gastric cancer phenotypes via heat shock factor 1-mediated secretion of extracellular vesicles
-
ACK1 is dispensable for development, skin tumor formation, and breast cancer cell proliferation
-
Proteolysis Targeting Chimeras for BTK Efficiently Inhibit B-Cell Receptor Signaling and Can Overcome Ibrutinib Resistance in CLL Cells
-
The evolutionarily conserved long non-coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms
-
Astrocytes Downregulate Inflammation in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome: Applicability to COVID-19
-
Albumin-Methotrexate Prodrug Analogues That Undergo Intracellular Reactivation Following Entrance into Cancerous Glioma Cells
-
Decoupling epithelial-mesenchymal transitions from stromal profiles by integrative expression analysis
-
Treatment results from a phase I study of WST11 phototherapy (VTP) for upper tract urothelial carcinoma
-
The Collagen-Modifying Enzyme PLOD2 Is Induced and Required during L1-Mediated Colon Cancer Progression
-
Accelerating AXL targeting for TNBC therapy
-
Putative Blood Somatic Mutations in Post-Traumatic Stress Disorder-Symptomatic Soldiers: High Impact of Cytoskeletal and Inflammatory Proteins
-
Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy
-
IRS1 phosphorylation underlies the non-stochastic probability of cancer cells to persist during EGFR inhibition therapy
-
Neoadjuvant vascular-targeted photodynamic therapy improves survival and reduces recurrence and progression in a mouse model of urothelial cancer
-
Transient genomic instability drives tumorigenesis through accelerated clonal evolution
-
Recurrent deletions in clonal hematopoiesis are driven by microhomology-mediated end joining
-
Meningeal lymphoid structures are activated under acute and chronic spinal cord pathologies
-
Aberrant transcriptional and post-transcriptional regulation of SPAG5, a YAP-TAZ-TEAD downstream effector, fuels breast cancer cell proliferation
-
Proteogenomics of glioblastoma associates molecular patterns with survival
-
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation
-
Immunoediting role for major vault protein in apoptotic signaling induced by bacterial N-acyl homoserine lactones
-
Engineered variants of the Ras effector protein RASSF5 (NORE1A) promote anti-cancer activities in lung adenocarcinoma
-
Whole-exome sequencing of HPV positive tonsillar and base of tongue squamous cell carcinomas reveals a global mutational pattern along with relapse-specific somatic variants
-
Microbiome and cancer
-
Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ)
-
MEK inhibition reverses aberrant signaling in melanoma cells through reorganization of NRas and BRAF in self nano-clusters
-
Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts
-
Microtubule destabilization is a critical checkpoint of chemotaxis and transendothelial migration in melanoma cells but not in T cells
-
P32-specific CAR T cells with dual antitumor and antiangiogenic therapeutic potential in gliomas
-
Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis
-
SCIRT lncRNA Restrains Tumorigenesis by Opposing Transcriptional Programs of Tumor-Initiating Cells
-
Tumor cells in light-chain amyloidosis and myeloma show different transcriptional rewiring of normal plasma cell development
-
β2-Integrin Adhesion Regulates Dendritic Cell Epigenetic and Transcriptional Landscapes to Restrict Dendritic Cell Maturation and Tumor Rejection
-
PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
-
Intratumoral heterogeneity in cancer progression and response to immunotherapy
-
Retrospective cell lineage reconstruction in humans by using short tandem repeats
-
Targeting autocrine amphiregulin robustly and reproducibly inhibits ovarian cancer in a syngeneic model: roles for wildtype p53
-
Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response
-
Systematic detection of m6A-modified transcripts at single-molecule and single-cell resolution
-
Deuterium MRSI characterizations of glucose metabolism in orthotopic pancreatic cancer mouse models
-
Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression
-
Effect of Ibrutinib on the IFN Response of Chronic Lymphocytic Leukemia Cells
-
Stromal Expression of the Core Clock Gene Period 2 Is Essential for Tumor Initiation and Metastatic Colonization
-
Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation
-
The microbiome and cytosolic innate immune receptors
-
Myotubularin-related protein 7 activates peroxisome proliferator-activated receptor-gamma
-
Regulation of eIF2α by RNF4 Promotes Melanoma Tumorigenesis and Therapy Resistance
-
Modeling Multiplexed Images with Spatial-LDA Reveals Novel Tissue Microenvironments
-
Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma
-
Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity
-
Genomic retargeting of p53 and CTCF is associated with transcriptional changes during oncogenic HRas-induced transformation
-
A single cell atlas of the human liver tumor microenvironment
-
Induction and characterization of pancreatic cancer in a transgenic pig model
-
Direct stimulation of ERBB2 highlights a novel cytostatic signaling pathway driven by the receptor-Thr(701) phosphorylation
-
Mutant p53 oncogenicity: dominant-negative or gain-of-function?
-
Developments in Vascular-Targeted Photodynamic Therapy for Urologic Malignancies
-
The pro-oncogenic effect of the lncRNA H19 in the development of chronic inflammation-mediated hepatocellular carcinoma
-
Predicting and affecting response to cancer therapy based on pathway-level biomarkers
-
Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth
-
Targeting HER3, a Catalytically Defective Receptor Tyrosine Kinase, Prevents Resistance of Lung Cancer to a Third-Generation EGFR Kinase Inhibitor
-
A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma
-
Interleukin 10 Restores Lipopolysaccharide-Induced Alterations in Synaptic Plasticity Probed by Repetitive Magnetic Stimulation
-
Reduction in MLKL-mediated endosomal trafficking enhances the TRAIL-DR4/5 signal to increase cancer cell death
-
Mitochondrial carrier homolog 2 is necessary for AML survival
-
A framework for advancing our understanding of cancer-associated fibroblasts
-
A single-cell landscape of high-grade serous ovarian cancer
-
Rational design of universal immunotherapy for TfR1-tropic arenaviruses
-
Immune related proteins and tumor infiltrating CD8+lymphocytes in hypopharyngeal cancer in relation to human papillomavirus (HPV) and clinical outcome
-
Pleiotropic tumor suppressor functions of WWOX antagonize metastasis
-
NF-κB-miR-155 axis activation mediates ovulation-induced oncogenic effects in fallopian tube epithelium
-
Modeling biological and genetic diversity in upper tract urothelial carcinoma with patient derived xenografts
-
Optimal multiparametric set-up modelled for best survival outcomes in palliative treatment of liver malignancies: unsupervised machine learning and 3 PM recommendations
-
Single-cell analysis of clonal maintenance of transcriptional and epigenetic states in cancer cells
-
Immunomodulatory Properties of Leishmania Extracellular Vesicles During Host-Parasite Interaction: Differential Activation of TLRs and NF-kappa B Translocation by Dermotropic and Viscerotropic Species
-
The Glioma Stem Cell Model in the Era of Single-Cell Genomics
-
Inter-Tumor Heterogeneity-Melanomas Respond Differently to GM-CSF-Mediated Activation
-
Microbiome genomics for cancer prediction
-
Breast Cancer-Derived Microparticles Reduce Cancer Cell Adhesion, an Effect Augmented by Chemotherapy
-
Time-resolved profiling reveals ATF3 as a novel mediator of endocrine resistance in breast cancer
-
CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy
-
Effect of IV Administration of a Gadolinium-Based Contrast Agent on Breast Diffusion-Tensor Imaging
-
Nanobodies Targeting Prostate-specific Membrane Antigen for the Imaging and Therapy of Prostate Cancer
-
Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models
-
Emerging roles of ECM remodeling processes in cancer
-
Cardiac remodeling secondary to chronic volume overload is attenuated by a novel MMP9/2 blocking antibody
-
Immunological Features of Non-neuronal Brain Cells: Implications for Alzheimer's Disease Immunotherapy
-
A Unified Linear Viscoelastic Model of the Cell Nucleus Defines the Mechanical Contributions of Lamins and Chromatin
-
The human tumor microbiome is composed of tumor type-specific intracellular bacteria
-
The biomarkers of hyperprogressive disease in PD-1/PD-L1 blockage therapy
-
Interleukin-10 Prevents Pathological Microglia Hyperactivation following Peripheral Endotoxin Challenge
-
IL-16 processing in sentinel node regulatory T cells is a factor in bladder cancer immunity
-
Diffusion-weighted breast MRI of malignancies with submillimeter resolution and immunity to artifacts by spatiotemporal encoding at 3T
-
Malignant cell-specific CXCL14 promotes tumor lymphocyte infiltration in oral cavity squamous cell carcinoma
-
Increased circulatory IL-6 during 8-week fluoxetine treatment is a risk factor for suicidal behaviors in youth
-
Wnt/β-catenin target genes in colon cancer metastasis: The special case of l1cam
-
Diffusivity in breast malignancies analyzed for b > 1000 s/mm 2 at 1 mm in‐plane resolutions: Insight from Gaussian and non‐Gaussian behaviors
-
Single-cell genomic approaches for developing the next generation of immunotherapies
-
Lipid Transfer Proteins and Membrane Contact Sites in Human Cancer
-
Dasatinib response in acute myeloid leukemia is correlated with FLT3/ITD, PTPN11 mutations and a unique gene expression signature
-
Bystander IFN-gamma activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment
-
Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia
-
A 20-Year Journey from Axonal Injury to Neurodegenerative Diseases and the Prospect of Immunotherapy for Combating Alzheimer's Disease
-
Intravital imaging of vascular anomalies and extracellular matrix remodeling in orthotopic pancreatic tumors
-
High-resolution optoacoustic imaging of tissue responses to vascular-targeted therapies
-
A Division of Labor between YAP and TAZ in Non-Small Cell Lung Cancer
-
High-Throughput Screen Identifies Host and Microbiota Regulators of Intestinal Barrier Function
-
Identification of a potent and selective covalent Pin1 inhibitor
-
Directed evolution of therapeutic antibodies targeting glycosylation in cancer
-
DNA Repair Biomarker for Lung Cancer Risk and its Correlation With Airway Cells Gene Expression
-
The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic
-
Introducing PIONEER: a project to harness big data in prostate cancer research
-
The potential anti-inflammatory and anti-nociceptive effects of rat hemopressin (PVNFKFLSH) in experimental arthritis
-
Nasopharyngeal carcinoma joins the single-cell party
-
Trypanosoma cruzi-Infected Human Macrophages Shed Proinflammatory Extracellular Vesicles That Enhance Host-Cell Invasion via Toll-Like Receptor 2
-
Characterization of the human tumor microbiome reveals tumor-type specific intra-cellular bacteria
-
beta-Catenin safeguards the ground state of mouse pluripotency by strengthening the robustness of the transcriptional apparatus
-
Transcriptional profiling reveals a subset of human breast tumors that retain wt TP53 but display mutant p53-associated features
-
Modeling Heterogeneity of Triple-Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance
-
Mapping cell phenotypes in breast cancer
-
Dual-Targeted Autoimmune Sword in Fatal Epilepsy: Patient's glutamate receptor AMPA GluR3B peptide autoimmune antibodies bind, induce Reactive Oxygen Species (ROS) in, and kill both human neural cells and T cells
-
Across the Globe: Proteogenomic Landscapes of Lung Cancer
-
Publisher Correction: Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome
-
Metabolic alterations in the tumor microenvironment and their role in oncogenesis
-
Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma
-
Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer
-
Targeting Metabolic Plasticity and flexibility Dynamics for Cancer Therapy
-
Treatment of Multiple Myeloma Using Chimeric Antigen Receptor T Cells with Dual Specificity
-
NOP10 predicts lung cancer prognosis and its associated small nucleolar RNAs drive proliferation and migration
-
The Animal Lectin Galectin-8 Promotes Cytokine Expression and Metastatic Tumor Growth in Mice
-
Deconstructing tumor heterogeneity: the stromal perspective
-
Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome
-
Golgi organization is regulated by proteasomal degradation
-
HSF1 and Molecular Chaperones in Biology and Cancer
-
Roles for receptor tyrosine kinases in tumor progression and implications for cancer treatment
-
Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action
-
Novel Proteome Extraction Method Illustrates a Conserved Immunological Signature of MSI-H Colorectal Tumors.
-
Tumour heterogeneity and the evolutionary trade-offs of cancer
-
Efficient targeted degradation via reversible and irreversible covalent PROTACs
-
PRMT1 inhibition induces differentiation of colon cancer cells
-
Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma
-
Intravital visualization of interactions of murine Peyer's patch-resident dendritic cells with M cells
-
Cellular Origins of the Lymphatic Endothelium: Implications for Cancer Lymphangiogenesis: Implications for Cancer Lymphangiogenesis
-
Fluorescent Silica Nanoparticles to Label Metastatic Tumor Cells in Mineralized Bone Microenvironments
-
Bone marrow dendritic cells support the survival of chronic lymphocytic leukemia cells in a CD84 dependent manner
-
Integration of intra-sample contextual error modeling for improved detection of somatic mutations from deep sequencing
-
Donor cell leukemia: reappearance of gene mutations in donor cells - more than an incidental phenomenon?
-
Proteomic analysis of circulating extracellular vesicles identifies potential markers of breast cancer progression, recurrence, and response
-
Theileria parasites subvert E2F signaling to stimulate leukocyte proliferation
-
Hitting KRAS When It’s Down
-
Targeted therapy and drug resistance in triple-negative breast cancer: the EGFR axis
-
Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression
-
The Role of HSF1 and the Chaperone Network in the Tumor Microenvironment
-
PhISCS-BnB: a fast branch and bound algorithm for the perfect tumor phylogeny reconstruction problem
-
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
-
Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4(+) and PDPN+ CAFs to clinical outcome
-
Tackling the Many Facets of Glioblastoma Heterogeneity
-
Nuclear P38: Roles in Physiological and Pathological Processes and Regulation of Nuclear Translocation
-
Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors
-
Recent insights into the role of L1CAM in cancer initiation and progression
-
Super-resolution Ultrasound Imaging
-
Urinary Exosomes from Bladder Cancer Patients Show a Residual Cancer Phenotype despite Complete Pathological Downstaging
-
Leptin modulates gene expression in the heart and cardiomyocytes towards mitigating ischemia-induced damage
-
Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer
-
miR-17-92 and miR-106b-25 clusters regulate beta cell mitotic checkpoint and insulin secretion in mice
-
Cooperativity between stromal cytokines drives the invasive migration of human breast cancer cells
-
Author Correction: Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells (Scientific Reports, (2017), 7, 1, (16345), 10.1038/s41598-017-16558-0)
-
Prediction of PD-L1 inhibition effects for HIV-infected individuals
-
A universal anti-cancer vaccine: Chimeric invariant chain potentiates the inhibition of melanoma progression and the improvement of survival
-
Tumor diversity and the trade-off between universal cancer tasks
-
Imaging of Red-Shifted Light From Bioluminescent Tumors Using Fluorescence by Unbound Excitation From Luminescence
-
Adipocytes sensitize melanoma cells to environmental TGF-beta cues by repressing the expression of miR-211
-
Inhibition of a pancreatic cancer model by cooperative pairs of clinically approved and experimental antibodies
-
Cancer exome-based identification of tumor neo-antigens using mass spectrometry
-
Immunohistochemical quantification of partial-EMT in oral cavity squamous cell carcinoma primary tumors is associated with nodal metastasis
-
SLAMF9 regulates pDC homeostasis and function in health and disease
-
Long Noncoding RNA MALAT1 Regulates Cancer Glucose Metabolism by Enhancing mTOR-Mediated Translation of TCF7L2
-
Exome Sequencing of ABCB5 Identifies Recurrent Melanoma Mutations that Result in Increased Proliferative and Invasive Capacities
-
SLAMF receptors on normal and malignant B cells
-
The cancer microbiome
-
Single-Cell RNA Sequencing in Cancer: Lessons Learned and Emerging Challenges
-
AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer
-
Deciphering Human Tumor Biology by Single-Cell Expression Profiling
-
PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model
-
The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids
-
KLF4 sensitizes the colon cancer cell HCT-15 to cisplatin by altering the expression of HMGB1 and hTERT
-
Kinetic modeling of DUSP regulation in herceptin-resistant HER2-positive breast cancer
-
In vivo effects of temperature on the heart and pyloric rhythms in the crab Cancer borealis
-
RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBP alpha- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction
-
Liver and Steroid Hormones - Can a Touch of p53 Make a Difference?
-
Genome-wide miRNA methylome analysis in oral cancer: possible biomarkers associated with patient survival
-
Transient p53-Mediated Regenerative Senescence in the Injured Heart
-
Correction: RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells (vol 8, 653, 2018)
-
Hepatitis C virus core protein interacts with cellular metastasis suppressor Nm23-H1 and promotes cell migration and invasion
-
Corrigendum to 'p53 balances between tissue hierarchy and anarchy'
-
Modelling the role of dual specificity phosphatases in herceptin resistant breast cancer cell lines
-
Increased expression of cathepsin D is required for L1-mediated colon cancer progression
-
The role of the microbiome in NAFLD and NASH
-
N-Acetyl-L-Cysteine Supplement in Early Life or Adulthood Reduces Progression of Diabetes in Nonobese Diabetic Mice
-
Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma
-
Resistance to paclitaxel is associated with a variant of the gene BCL2 in multiple tumor types
-
Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion
-
Simultaneous Integration of Multi-omics Data Improves the Identification of Cancer Driver Modules
-
Reduced CTL motility and activity in avascular tumor areas
-
The transcriptional profile of circulating myeloid derived suppressor cells correlates with tumor development and progression in mouse
-
IKK epsilon regulates the breast cancer stem cell phenotype
-
c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression
-
The landscape of tiered regulation of breast cancer cell metabolism
-
The ADAM17 Protease Promotes Tobacco Smoke Carcinogen-induced Lung Tumourigenesis
-
The therapeutic potential of tuftsin-phosphorylcholine in giant cell arteritis
-
Proteomic and genomic signatures of repeat instability in cancer and adjacent normal tissues
-
Proteomic analysis reveals greater abundance of complement and inflammatory proteins in subcutaneous adipose tissue from postpartum cows treated with sodium salicylate
-
A cancer associated somatic mutation in LC3B attenuates its binding to E1-like ATG7 protein and subsequent lipidation
-
Accelerated Hypofractionated Radiation Therapy for Elderly Frail Bladder Cancer Patients Unfit for Surgery or Chemotherapy
-
Cross-Talk between Receptor Tyrosine Kinases AXL and ERBB3 Regulates Invadopodia Formation in Melanoma Cells
-
Daily light and darkness onset and circadian rhythms metabolically synchronize hematopoietic stem cell differentiation and maintenance: The role of bone marrow norepinephrine, tumor necrosis factor, and melatonin cycles
-
The circRNA-microRNA code: emerging implications for cancer diagnosis and treatment
-
Optimizing T-cell receptor avidity with somatic hypermutation
-
Cancer immunotherapy: The dawn of antibody cocktails
-
Increased Expression of MicroRNA 551a by c-Fos Reduces Focal Adhesion Kinase Levels and Blocks Tumorigenesis
-
Melanoma-derived extracellular vesicles instigate proinflammatory signaling in the metastatic microenvironment
-
Nonmuscle myosin IIA and IIB differentially modulate migration and alter gene expression in primary mouse tumorigenic cells
-
Immunization with mannosylated nanovaccines and inhibition of the immune-suppressing microenvironment sensitizes melanoma to immune checkpoint modulators
-
p53: not just a tumor suppressor
-
Gain-of-Function Mutant p53: All the Roads Lead to Tumorigenesis
-
ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer
-
RASA2 and NF1; two-negative regulators of Ras with complementary functions in melanoma
-
UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors
-
Cytokine sensitivity screening highlights BMP4 pathway signaling as a therapeutic opportunity in ER+ breast cancer
-
Histamine releasing factor and elongation factor 1 alpha secreted via malaria parasites extracellular vesicles promote immune evasion by inhibiting specific T cell responses
-
An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma
-
ISG15 induction is required during L1-mediated colon cancer progression and metastasis
-
Single-cell sequencing and its applications in head and neck cancer
-
Microvesicle Proteomic Profiling of Uterine Liquid Biopsy for Ovarian Cancer Early Detection
-
Evolutionary trajectory of leukemic clones and its clinical implications
-
Nuclear ERK: Mechanism of Translocation, Substrates, and Role in Cancer
-
Magnesium transporter 1 (MAGT1) deficiency causes selective defects in N-linked glycosylation and expression of immune-response genes
-
Connections Between Clonal Hematopoiesis, Cardiovascular Disease, and Cancer A Review
-
Specific inhibition of splicing factor activity by decoy RNA oligonucleotides
-
Effectiveness of the combination of vascular targeted photodynamic therapy and anti-cytotoxic T-lymphocyte-associated antigen 4 in a preclinical mouse model of urothelial carcinoma
-
New insights into YAP/TAZ nucleo-cytoplasmic shuttling: new cancer therapeutic opportunities?
-
Bacillus Calmette-Guerin (BCG) therapy lowers the incidence of Alzheimer's disease in bladder cancer patients
-
UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma
-
PIK3CA in cancer: The past 30 years
-
Scaling laws indicate distinct nucleation mechanisms of holes in the nuclear lamina
-
Transmissible inflammation-induced colorectal cancer in inflammasome-deficient mice
-
Exosomes as a storehouse of tissue remodeling proteases and mediators of cancer progression
-
Modulation of MS-like disease by a multi epitope protein is mediated by induction of CD11c(+) CD1lb(+) Grl(+) myeloid-derived dendritic cells
-
MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy
-
Cancer-Associated Eukaryotic Translation Initiation Factor 1A Mutants Impair Rps3 and Rps10 Binding and Enhance Scanning of Cell Cycle Genes
-
STAT3 Post-Translational Modifications Drive Cellular Signaling Pathways in Prostate Cancer Cells
-
MicroRNAs Affect Complement Regulator Expression and Mitochondrial Activity to Modulate Cell Resistance to Complement-Dependent Cytotoxicity
-
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
-
The Genomic and Immune Landscapes of Lethal Metastatic Breast Cancer
-
Potential immunotherapy for Alzheimer disease and age-related dementia
-
Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes
-
The HERV-K accessory protein Np9 controls viability and migration of teratocarcinoma cells
-
Fast dose fractionation using ultra-short laser accelerated proton pulses can increase cancer cell mortality, which relies on functional PARP1 protein
-
Biological implications of clonal hematopoiesis
-
Potentiating vascular-targeted photodynamic therapy through CSF-1R modulation of myeloid cells in a preclinical model of prostate cancer
-
Early Loss of Histone H2B Monoubiquitylation Alters Chromatin Accessibility and Activates Key Immune Pathways That Facilitate Progression of Ovarian Cancer
-
Mutant p53-a potential player in shaping the tumor-stroma crosstalk
-
Self-assembled micellar clusters based on Triton-X-family surfactants for enhanced solubilization, encapsulation, proteins permeability control, and anticancer drug delivery
-
RUNX represses Pmp22 to drive neurofibromagenesis
-
p53 balances between tissue hierarchy and anarchy
-
Facing the future: challenges and opportunities in adoptive T cell therapy in cancer
-
Oxidative stress and therapeutic development in lung cancer
-
The integrated stress response promotes B7H6 expression
-
Veto cells for safer nonmyeloablative haploidentical HSCT and CAR T cell therapy
-
Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence
-
Characterization of inv(3) cell line OCI-AML-20 with stroma-dependent CD34 expression
-
Can immunization with Bacillus Calmette-Guerin (BCG) protect against Alzheimer's disease?
-
Global DNA methylation reflects spatial heterogeneity and molecular evolution of lung adenocarcinomas
-
Hydrophobic Organic Components of Ambient Fine Particulate Matter (PM 2.5) Associated with Inflammatory Cellular Response.
-
Acid-Induced Downregulation of ASS1 Contributes to the Maintenance of Intracellular pH in Cancer
-
Prediction of ultra-high-order antibiotic combinations based on pairwise interactions
-
Data on peptidyl platform-based anticancer drug synthesis and triton-x-based micellar clusters (MCs) self-assembly peculiarities for enhanced solubilization, encapsulation of hydrophobic compounds and their interaction with HeLa cells
-
Phenotypic Screen Identifies JAK2 as a Major Regulator of FAT10 Expression
-
Mutant p53-dependent mitochondrial metabolic alterations in a mesenchymal stem cell-based model of progressive malignancy
-
p53 and the Viral Connection: Back into the Future
-
P53 shades of Hippo
-
The nuclear translocation of the kinases p38 and JNK promotes inflammation-induced cancer
-
Quantitative evaluation of breast cancer response to neoadjuvant chemotherapy by diffusion tensor imaging: Initial results
-
Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers
-
Does cancer strive to minimize the cost of gene expression?
-
Regulation of dual specificity phosphatases in breast cancer during initial treatment with Herceptin: a Boolean model analysis
-
Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma
-
Quantification and tracking of genetically engineered dendritic cells for studying immunotherapy
-
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
-
The Tumor Necrosis Factor Family: Family Conventions and Private Idiosyncrasies
-
Improvement and extension of anti-EGFR targeting in breast cancer therapy by integration with the Avidin-Nucleic-Acid-Nano-Assemblies
-
A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen
-
Mutated MITF-E87R in Melanoma Enhances Tumor Progression via S100A4
-
Systems modelling of the EGFR-PYK2-c-Met interaction network predicts and prioritizes synergistic drug combinations for triple-negative breast cancer
-
A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment
-
Rapid labelling and covalent inhibition of intracellular native proteins using ligand-directed N-acyl-N-alkyl sulfonamide
-
Direct Real-Time Monitoring of Prodrug Activation by Chemiluminescence
-
Intratumoral bacteria may elicit chemoresistance by metabolizing anticancer agents
-
Induction of Nitric-Oxide Metabolism in Enterocytes Alleviates Colitis and Inflammation-Associated Colon Cancer
-
Expansion and Antitumor Cytotoxicity of T-Cells Are Augmented by Substrate-Bound CCL21 and Intercellular Adhesion Molecule 1
-
Stepping out of the shadows: Oncogenic and tumor-promoting protein tyrosine phosphatases
-
International conference on Cell Death in Cancer and Toxicology 2018 (CDCT-2018)
-
Clinical Proteomics of Breast Cancer Reveals a Novel Layer of Breast Cancer Classification
-
Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer
-
Quiescin sulfhydryl oxidase 1 (QSOX1) glycosite mutation perturbs secretion but not Golgi localization
-
Single-Cell Genomics: A Stepping Stone for Future Immunology Discoveries
-
The Proteome of Prostate Cancer Bone Metastasis Reveals Heterogeneity with Prognostic Implications
-
Senescence and Telomere Homeostasis Might Be Involved in Placenta Percreta-Preliminary Investigation
-
NKp46 Receptor-Mediated Interferon-gamma Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis
-
Analysis of enzymatic activity of matrix metalloproteinase (MMP) by collagen zymography in Melanoma
-
Mining Plants for Bacterial Quorum Sensing Modulators
-
SUSHI: Sparsity-Based Ultrasound Super-Resolution Hemodynamic Imaging
-
Randomized Trial of Partial Gland Ablation with Vascular Targeted Phototherapy versus Active Surveillance for Low Risk Prostate Cancer: Extended Followup and Analyses of Effectiveness
-
Fresh water, marine and terrestrial cyanobacteria display distinct allergen characteristics
-
The tolerogenic peptide hCDR1 immunomodulates cytokine and regulatory molecule gene expression in blood mononuclear cells of primary Sjogren's syndrome patients
-
Ex-vivo organ culture as potential prioritization tool for breast cancer targeted therapy
-
Harnessing synthetic lethality to predict the response to cancer treatment
-
Cell-cell adhesion: linking Wnt/β-catenin signaling with partial EMT and stemness traits in tumorigenesis
-
New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins
-
Systemic antitumor immunity by PD-1/PD-L1 inhibition is potentiated by vascular-targeted photodynamic therapy of primary tumors
-
Phagocyte-extracellular matrix crosstalk empowers tumor development and dissemination
-
Prediction of acute myeloid leukaemia risk in healthy individuals
-
CAPN1 is a novel binding partner and regulator of the tumor suppressor NF1 in melanoma
-
Refinement of the endogenous epitope tagging technology allows the identification of a novel NRAS binding partner in melanoma
-
Single cell RNA-seq highlights a role for a partial EMT in head and neck cancer
-
Proceedings From the Fourth Haploidentical Stem Cell Transplantation Symposium (HAPLO2016), San Diego, California, December 1, 2016
-
Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures
-
Dual role of E-cadherin in the regulation of invasive collective migration of mammary carcinoma cells
-
PAX8 activates a p53-p21-dependent pro-proliferative effect in high grade serous ovarian carcinoma
-
An exploratory study of adolescent response to fluoxetine using psychological and biological predictors
-
Toxicity of an Fc-engineered anti-CD40 antibody is abrogated by intratumoral injection and results in durable antitumor immunity
-
A sorafenib-sparing effect in the treatment of thyroid carcinoma cells attained by co-treatment with a novel isoflavone derivative and 1,25 dihydroxyvitamin D3
-
Molecular mechanisms underlying the role of galectin-8 as a regulator of cancer growth and metastasis
-
Nonredundant, highly connected microRNAs control functionality in breast cancer networks
-
Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma
-
A Combination of Approved Antibodies Overcomes Resistance of Lung Cancer to Osimertinib by Blocking Bypass Pathways
-
Rewiring urea cycle metabolism in cancer to support anabolism
-
IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer
-
A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation
-
Microenvironment-induced CD44v6 promotes early disease progression in chronic lymphocytic leukemia
-
A biological-computational human cell lineage discovery platform based on duplex molecular inversion probes
-
Differentiation Between Vasogenic Edema and Infiltrative Tumor in Patients With High-Grade Gliomas Using Texture Patch-Based Analysis
-
Loss of C/EBP-beta LIP drives cisplatin resistance in malignant pleural mesothelioma
-
p53 in Bronchial Club Cells Facilitates Chronic Lung Inflammation by Promoting Senescence
-
Androgen deprivation therapy potentiates the efficacy of vascular targeted photodynamic therapy of prostate cancer xenografts
-
Functional characterization of the p53 "mutome"
-
A modular platform for targeted RNAi therapeutics
-
Efficient Therapeutic Protein Expression Using Retroviral Replicating Vector with 2A Peptide in Cancer Models
-
A Mutant p53-Dependent Embryonic Stem Cell Gene Signature Is Associated with Augmented Tumorigenesis of Stem Cells
-
LATS1 and LATS2 suppress breast cancer progression by maintaining cell identity and metabolic state
-
ICAMs Are Not Obligatory for Functional Immune Synapses between Naive CD4 T Cells and Lymph Node DCs
-
Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition
-
Caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion
-
Small Molecules Co-targeting CKI alpha and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models
-
Increasing intratumor C/EBP- LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer
-
The anti-inflammatory IFITM genes ameliorate colitis and partially protect from tumorigenesis by changing immunity and microbiota
-
The immune system profoundly restricts intratumor genetic heterogeneity
-
Delivery of ROS Generating Anthraquinones Using Reduction-Responsive Peptide-Based Nanoparticles
-
Helminths-based bi-functional molecule, tuftsin-phosphorylcholine (TPC), ameliorates an established murine arthritis
-
MRI radiomics analysis of molecular alterations in low-grade gliomas
-
An oligoclonal antibody durably overcomes resistance of lung cancer to third-generation EGFR inhibitors
-
Soluble SLAMF6 Receptor Induces Strong CD8 + T-cell Effector Function and Improves Anti-Melanoma Activity In Vivo
-
Nanoparticulate vaccine inhibits tumor growth via improved T cell recruitment into melanoma and huHER2 breast cancer
-
A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies
-
The intestinal stem cell regulating gene ASCL2 is required for L1-mediated colon cancer progression
-
Assembly and activation of the Hippo signalome by FAT1 tumor suppressor
-
Optimized dendritic cell vaccination induces potent CD8 T cell responses and anti-tumor effects in transgenic mouse melanoma models
-
A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging
-
TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma
-
Autophagy differentially regulates TNF receptor Fn14 by distinct mammalian Atg8 proteins
-
Arginine and the metabolic regulation of nitric oxide synthesis in cancer
-
Intratumor heterogeneity in epigenetic patterns
-
The oncogenic fusion protein CBFB-SMMHC downregulates CD48 to evade NK cell recognition
-
A phase I-II clinical trial of the anti-CD74 monoclonal antibody milatuzumab in frail patients with refractory chronic lymphocytic leukaemia: A patient based approach
-
LPS-mediated cell surface expression of CD74 promotes the proliferation of B cells in response to MIF
-
The HTLV-1 gp21 fusion peptide inhibits antigen specific T-cell activation in-vitro and in mice
-
Laplacian pyramid based data fusion for high resolution dynamic MRI
-
Brain investigations of rodent disease models by chemical exchange saturation transfer at 21.1T
-
SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors
-
Various stress stimuli rewire the profile of liver secretome in a p53-dependent manner
-
RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells
-
MiRNA-513a-5p inhibits progesterone receptor expression and constitutes a risk factor for breast cancer: The hOrmone and Diet in the ETiology of breast cancer prospective study
-
Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability
-
CD84 regulates PD-1/PD-L1 expression and function in chronic lymphocytic leukemia
-
Altered p53 functionality in cancer-associated fibroblasts contributes to their cancer-supporting features
-
WST11 Vascular Targeted Photodynamic Therapy Effect Monitoring by Multispectral Optoacoustic Tomography (MSOT) in Mice
-
Cancer research in the era of immunogenomics
-
The PTPROt tyrosine phosphatase functions as an obligate haploinsufficient tumor suppressor in vivo in B-cell chronic lymphocytic leukemia
-
Degradation of Bcl-2 by XIAP and ARTS Promotes Apoptosis
-
Dynamic proteomics reveals bimodal protein dynamics of cancer cells in response to HSP90 inhibitor
-
Augmented expression of RUNX1 deregulates the global gene expression of U87 glioblastoma multiforme cells and inhibits tumor growth in mice
-
Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine
-
Runx3 in Immunity, Inflammation and Cancer
-
Diverse p53/DNA binding modes expand the repertoire of p53 response elements
-
A point mutation in the extracellular domain of L1 blocks its capacity to confer metastasis in colon cancer cells via CD10
-
Increased NK cell immunity in a transgenic mouse model of NKp46 overexpression
-
Real Time Laser Speckle Imaging Monitoring Vascular Targeted Photodynamic Therapy
-
A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
-
p53 is essential for DNA methylation homeostasis in naive embryonic stem cells, and its loss promotes clonal heterogeneity
-
Light-Stimulated Generation of Free Radicals by Quinones-Chelators
-
CD84 mediates CLL-microenvironment interactions
-
Contrast enhanced ultrasound imaging can predict vascular-targeted photodynamic therapy induced tumor necrosis in small animals
-
Non-canonical NF kappa B mutations reinforce pro-survival TNF response in multiple myeloma through an autoregulatory RelB: p50 NF kappa B pathway
-
Matrix Mechanosensing: From Scaling Concepts in 'Omics Data to Mechanisms in the Nucleus, Regeneration, and Cancer
-
The short and the long: non-coding RNAs and growth factors in cancer progression
-
Biological and clinical consequences of NPM1 mutations in AML
-
p53 on the crossroad between regeneration and cancer
-
The nonreceptor tyrosine kinase c-Src attenuates SCF(beta-TrCP) E3-ligase activity abrogating Taz proteasomal degradation
-
Metabolic Circuit Involving Free Fatty Acids, microRNA 122, and Triglyceride Synthesis in Liver and Muscle Tissues
-
Can immunotherapy treat neurodegeneration?
-
From Prokaryotes to Cancer: Glutamine Flux in Multicellular Units
-
Fast Vascular Ultrasound Imaging With Enhanced Spatial Resolution and Background Rejection
-
Tumor Suppression by p53: Bring in the Hippo!
-
Next-Generation Proteomics and Its Application to Clinical Breast Cancer Research
-
Activation of Signaling Cascades by Weak Extremely Low Frequency Electromagnetic Fields
-
p21 maintains senescent cell viability under persistent DNA damage response by restraining JNK and caspase signaling
-
Targeting of apoptotic pathways by SMAC or BH3 mimetics distinctly sensitizes paclitaxel-resistant triple negative breast cancer cells
-
Newly Formed Endothelial Cells Regulate Myeloid Cell Activity Following Spinal Cord Injury via Expression of CD200 Ligand
-
Immune deficiency augments the prevalence of p53 loss of heterozygosity in spontaneous tumors but not bi-directional loss of heterozygosity in bone marrow progenitors
-
The human lncRNA LINC-PINT inhibits tumor cell invasion through a highly conserved sequence element
-
Von Hippel-Lindau and Hereditary Pheochromocytoma/Paraganglioma Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood
-
Integrating multiple fitting regression and Bayes decision for cancer diagnosis with transcriptomic data from tumor-educated blood platelets
-
Herpesviruses shape tumour microenvironment through exosomal transfer of viral microRNAs
-
The LATS1 and LATS2 tumor suppressors: beyond the Hippo pathway
-
The microbiome in anti-cancer therapy
-
FXYD5 (dysadherin) may mediate metastatic progression through regulation of the beta-Na+-K+-ATPase subunit in the 4T1 mouse breast cancer model
-
Lymphocyte activation gene 3: a novel therapeutic target in chronic lymphocytic leukemia
-
Classification of High-Grade Glioma into Tumor and Nontumor Components Using Support Vector Machine
-
Regulatory module involving FGF13, miR-504, and p53 regulates ribosomal biogenesis and supports cancer cell survival
-
McPAS-TCR: a manually curated catalogue of pathology-associated T cell receptor sequences
-
SMYD2 lysine methyltransferase regulates leukemia cell growth and regeneration after genotoxic stress
-
Cancer and Central Nervous System Tumor Surveillance in Pediatric Neurofibromatosis 1
-
Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses
-
Pyruvate dehydrogenase has a major role in mast cell function, and its activity is regulated by mitochondrial microphthalmia transcription factor
-
BCAT1 restricts alpha KG levels in AML stem cells leading to IDHmut-like DNA hypermethylation
-
Increased potency of a bi-specific TL1A-ADAM17 (TACE) inhibitor by cell surface targeting
-
p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis
-
Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells
-
A recombinant fungal compound induces anti-proliferative and pro-apoptotic effects on colon cancer cells
-
Death by over-eating: The Gaucher disease associated gene GBA1, identified in a screen for mediators of autophagic cell death, is necessary for developmental cell death in Drosophila midgut
-
Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases
-
miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis
-
Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome
-
Synonymous Somatic Variants in Human Cancer Are Not Infamous: A Plea for Full Disclosure in Databases and Publications
-
Jaspine B induces nonapoptotic cell death in gastric cancer cells independently of its inhibition of ceramide synthase
-
Tracing the origins of relapse in acute myeloid leukaemia to stem cells
-
Bombesin Antagonist-Based Radiotherapy of Prostate Cancer Combined with WST-11 Vascular Targeted Photodynamic Therapy
-
Spontaneous Activation of Antigen-presenting Cells by Genes Encoding Truncated Homo-Oligomerizing Derivatives of CD40
-
Post-translational regulation of p53 function through 20S proteasome-mediated cleavage
-
Pancreatic cancer ascites xenograft-an expeditious model mirroring advanced therapeutic resistant disease
-
Cancer and Central Nervous System Tumor Surveillance in Pediatric Neurofibromatosis 2 and Related Disorders
-
The cancer paradigms of mammalian regeneration: can mammals regenerate as amphibians?
-
AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia
-
The Leo Sachs' legacy: a pioneer's journey through hematopoiesis
-
Genetic and Functional Analysis of GRIN2A in Tumor Samples
-
Systematic Epigenomic Analysis Reveals Chromatin States Associated with Melanoma Progression
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Diverse continuum of CD4+ T-cell states is determined by hierarchical additive integration of cytokine signals
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Culturing CTLs under Hypoxic Conditions Enhances Their Cytolysis and Improves Their Anti-tumor Function
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Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors
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Recommendations for Surveillance for Children with Leukemia-Predisposing Conditions
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RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer
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Receptor Protein Tyrosine Phosphatase alpha-Mediated Enhancement of Rheumatoid Synovial Fibroblast Signaling and Promotion of Arthritis in Mice
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TMPRSS2-ERG fusion protein regulates insulin-like growth factor-1 receptor (IGF1R) gene expression in prostate cancer: involvement of transcription factor Sp1
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Co-targeting of Adenosine Signaling Pathways for Immunotherapy: Potentiation by Fc Receptor Engagement
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Measurement of lymphocyte aggregation by flow cytometry-physiological implications in chronic lymphocytic leukemia
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Wnt signaling in cancer stem cells and colon cancer metastasis.
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MicroRNA-182 targets SMAD7 to potentiate TGF beta-induced epithelial-mesenchymal transition and metastasis of cancer cells
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p53 elevation in human cells halt SV40 infection by inhibiting T-ag expression
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The Relationship Between Plasma Cytokine Levels and Response to Selective Serotonin Reuptake Inhibitor Treatment in Children and Adolescents with Depression and/or Anxiety Disorders
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Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer
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NKG2D ligands mediate immunosurveillance of senescent cells
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Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies
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Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis
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LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer.
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The relationship between the nucleolus and cancer: Current evidence and emerging paradigms
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Tumor macrophages are pivotal constructors of tumor collagenous matrix
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The Hippo pathway, p53 and cholesterol.
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Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL.
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Oncogenic Mutant p53 Gain of Function Nourishes the Vicious Cycle of Tumor Development and Cancer Stem-Cell Formation
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System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis
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FXYD5 Protein Has a Pro-inflammatory Role in Epithelial Cells
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Analysis of Subcellular RNA Fractions Revealed a Transcription-Independent Effect of Tumor Necrosis Factor Alpha on Splicing, Mediated by Spt5.
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Adipose-Induced Retroperitoneal Soft Tissue Sarcoma Tumorigenesis: A Potential Crosstalk between Sarcoma and Fat Cells
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The cybernetics of TNF: Old views and newer ones
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mRNA-based dendritic cell immunization improves survival in ret transgenic mouse melanoma model
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Mutational and network level mechanisms underlying resistance to anti-cancer kinase inhibitors
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Interfering with the Dimerization of the ErbB Receptors by Transmembrane Domain-Derived Peptides Inhibits Tumorigenic Growth in Vitro and in Vivo
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Differential regulated microRNA by wild type and mutant p53 in induced pluripotent stem cells
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The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation.
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p53 mutations promote proteasomal activity
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Dynamics inside the cancer cell attractor reveal cell heterogeneity, limits of stability, and escape
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Non-alcoholic fatty liver and the gut microbiota.
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Widespread parainflammation in human cancer
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A metabolic link between the urea cycle and cancer cell proliferation
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Tumor cell invasion can be blocked by modulators of collagen fibril alignment that control assembly of the extracellular matrix.
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Treatment Effects of WST11 Vascular Targeted Photodynamic Therapy for Urothelial Cell Carcinoma in Swine
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Estrogen Receptor-Targeted Contrast Agents for Molecular Magnetic Resonance Imaging of Breast Cancer Hormonal Status
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Tumor Necrosis Factor Alpha (TNFalpha)
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Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
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Novel p53 target genes secreted by the liver are involved in non-cell-autonomous regulation
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Parkinson disease (PARK) genes are somatically mutated in cutaneous melanoma
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The involvement of mutant Rac1 in the formation of invadopodia in cultured melanoma cells
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The evolution of T-cell depletion in haploidentical stem-cell transplantation
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Microglia Replenished OHSC: A Culture System to Study In Vivo Like Adult Microglia
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Breast MRI: Malignant Cystosarcoma Phyllodes Tumor Exhibits Unique Anisotropic Diffusion
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Optimization of DCE-MRI protocol for the assessment of patients with brain tumors
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Immunotherapy of cancer: from monoclonal to oligoclonal cocktails of anti-cancer antibodies: IUPHAR Review 18.
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Post-translational modification profiling - A novel tool for mapping the protein modification landscape in cancer
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An antibody to amphiregulin, an abundant growth factor in patients' fluids, inhibits ovarian tumors.
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Adjuvant Autologous Melanoma Vaccine for Macroscopic Stage III Disease: Survival, Biomarkers, and Improved Response to CTLA-4 Blockade
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Genetic and Pharmacological Modulation of Akt1 for Improving Ovarian Graft Revascularization in a Mouse Model
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Extracellular matrix and tissue regeneration
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Harnessing the natural inhibitory domain to control TNF alpha Converting Enzyme (TACE) activity in vivo
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Serum thioredoxin reductase is highly increased in mice with hepatocellular carcinoma and its activity is restrained by several mechanisms
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RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer
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Targeting mutant p53 for cancer therapy
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Emerging anti-cancer antibodies and combination therapies targeting HER3/ERBB3
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Tumour suppressor death-associated protein kinase targets cytoplasmic HIF-1 alpha for Th17 suppression
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Intrinsic superoxide dismutase activity of MnO nanoparticles enhances the magnetic resonance imaging contrast
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Genetic manipulation of iron biomineralization enhances MR relaxivity in a ferritin-M6A chimeric complex
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Androgen deprivation therapy potentiates the efficacy of vascular targeted photodynamic therapy of prostate cancer xenografts
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M-sec regulates polarized secretion of inflammatory endothelial chemokines and facilitates CCL2-mediated lymphocyte transendothelial migration
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Fibroblast recruitment as a tool for ovarian cancer detection and targeted therapy
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A module of inflammatory cytokines defines resistance of colorectal cancer to EGFR inhibitors
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Mutational scanning reveals the determinants of protein insertion and association energetics in the plasma membrane.
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Coronary vasculature patterning requires a novel endothelial ErbB2 holoreceptor
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MicroRNAs: Non-coding fine tuners of receptor tyrosine kinase signalling in cancer
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A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns
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A network-based analysis of colon cancer splicing changes reveals a tumorigenesis-favoring regulatory pathway emanating from ELK1
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Use of HLA peptidomics and whole exome sequencing to identify human immunogenic neo-antigens
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The Anticancer Activity of Organotelluranes: Potential Role in Integrin Inactivation
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Breast cancer tumorigenicity is dependent on high expression levels of NAF-1 and the lability of its Fe-S clusters
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Can diffusion tensor anisotropy indices assist in breast cancer detection?
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Cancer therapeutic approach based on conformational stabilization of mutant p53 protein by small peptides
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Proteomic maps of breast cancer subtypes
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Therapeutic Potential of T Cell Chimeric Antigen Receptors (CARs) in Cancer Treatment: Counteracting Off-Tumor Toxicities for Safe CAR T Cell Therapy
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Genomic Alterations Observed in Colitis-Associated Cancers Are Distinct From Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease.
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Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery
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The Proteome of Primary Prostate Cancer
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Role of the microbiome in non-gastrointestinal cancers.
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Differentiation between treatment-related changes and progressive disease in patients with high grade brain tumors using support vector machine classification based on DCE MRI
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Zooming in on selectins in cancer
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Vascular-Targeted Photodynamic Therapy in Prostate Cancer: From Bench to Clinic
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HER2-Targeted Polyinosine/Polycytosine Therapy Inhibits Tumor Growth and Modulates the Tumor Immune Microenvironment
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The tumor as an organ: comprehensive spatial and temporal modeling of the tumor and its microenvironment.
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Parkin Somatic Mutations Link Melanoma and Parkinson's Disease
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Tumor Evolution Inferred by Patterns of microRNA Expression through the Course of Disease, Therapy, and Recurrence in Breast Cancer
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Cellular heterogeneity mediates inherent sensitivity–specificity tradeoff in cancer targeting by synthetic circuits
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A non-aggressive, highly efficient, enzymatic method for dissociation of human brain-tumors and brain-tissues to viable single-cells
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Conjugation of Methotrexate-Amino Derivatives to Macromolecules through Carboxylate Moieties Is Superior Over Conventional Linkage to Amino Residues: Chemical, Cell-Free and In Vitro Characterizations
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Increased number of volatile organic compounds over malignant glottic lesions.
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An essential role for UTX in resolution and activation of bivalent promoters
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SLP76 integrates into the B-cell receptor signaling cascade in chronic lymphocytic leukemia cells and is associated with an aggressive disease course
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Erratum to: ‘Phosphoproteomic analysis reveals Smarcb1 dependent EGFR signaling in Malignant Rhabdoid tumor cells’
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The Wnt target gene L1 in colon cancer invasion and metastasis
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Protein Sialylation Regulates a Gene Expression Signature that Promotes Breast Cancer Cell Pathogenicity
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The EGFR-HER2 module: a stem cell approach to understanding a prime target and driver of solid tumors
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Improved Doxorubicin Encapsulation and Pharmacokinetics of Ferritin-Fusion Protein Nanocarriers Bearing Proline, Serine, and Alanine Elements
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The ERK cascade inhibitors: Towards overcoming resistance
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Chronic centrosome amplification without tumorigenesis
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A statistical framework to model the meeting-in-the-middle principle using metabolomic data: application to hepatocellular carcinoma in the EPIC study
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Examination of HER3 targeting in cancer using monoclonal antibodies
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Preleukemia: The normal side of cancer
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AML evolution from preleukemia to leukemia and relapse.
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Reactivation of epigenetically silenced miR-512 and miR-373 sensitizes lung cancer cells to cisplatin and restricts tumor growth
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Fc gamma Rs Modulate the Anti-tumor Activity of Antibodies Targeting the PD-1/PD-L1 Axis
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A principle of organization which facilitates broad Lamarckian-like adaptations by improvisation.
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In the Hunt for Therapeutic Targets: Mimicking the Growth, Metastasis, and Stromal Associations of Early-Stage Lung Cancer Using a Novel Orthotopic Animal Model
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Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells
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An Interactive Tool for Animating Biology, and Its Use in Spatial and Temporal Modeling of a Cancerous Tumor and Its Microenvironment
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Phosphorylcholine-tuftsin compound prevents development of dextransulfate-sodium-salt induced murine colitis: Implications for the treatment of human inflammatory bowel disease
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Erratum: A Senescence-Inflammatory Switch from Cancer-Inhibitory to Cancer-Promoting Mechanism (vol 24, pg 242, 2013)
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Development of APE1 enzymatic DNA repair assays: low APE1 activity is associated with increase lung cancer risk.
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Quantitative computerized western blotting in detail
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LPS-mediated septic shock is augmented in ceramide synthase 2 null mice due to elevated activity of TNF alpha-converting enzyme
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Phosphoproteomic analysis reveals Smarcb1 dependent EGFR signaling in Malignant Rhabdoid tumor cells
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The functional relevance of somatic synonymous mutations in melanoma and other cancers
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Next generation HLA-haploidentical HSCT
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Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors
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Hyperpolarized NMR of plant and cancer cell extracts at natural abundance
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Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation
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Combining three antibodies nullifies feedback-mediated resistance to erlotinib in lung cancer
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Genomic Classification of Cutaneous Melanoma
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Clonal evolution models of tumor heterogeneity
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Clusterin, a gene enriched in intestinal stem cells, is required for L1-mediated colon cancer metastasis.
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Size controlled protein nanoemulsions for active targeting of folate receptor positive cells
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Age-associated inflammation connects RAS-induced senescence to stem cell dysfunction and epidermal malignancy
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Messenger RNA encoding constitutively active toll-like receptor 4 enhances effector functions of human T cells.
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PYK2 sustains endosomal-derived receptor signalling and enhances epithelial-to-mesenchymal transition
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Label-free in vivo molecular imaging of underglycosylated mucin-1 expression in tumour cells
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Mechanical interplay between invadopodia and the nucleus in cultured cancer cells
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Target discovery for T cell therapy: next steps to advance Immunotherapies
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Chemical cross-linking and native mass spectrometry: A fruitful combination for structural biology
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TOOKAD (R) Soluble focal therapy: pooled analysis of three phase II studies assessing the minimally invasive ablation of localized prostate cancer
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Electron spin resonance microscopic imaging of oxygen concentration in cancer spheroids
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Aging, clonal hematopoiesis and preleukemia: not just bad luck?
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Development of pheochromocytoma in ceramide synthase 2 null mice
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Runx3 at the interface of immunity, inflammation and cancer
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P53-dependent non-coding RNA networks in chronic lymphocytic leukemia
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Regulation and function of Myb-binding protein 1A (MYBBP1A) in cellular senescence and pathogenesis of head and neck cancer
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Dispersal of an ancient retroposon in the TP53 promoter of Bovidae: phylogeny, novel mechanisms, and potential implications for cow milk persistency
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c-Abl forces YAP to switch sides.
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Systemic Gene Silencing in Primary T Lymphocytes Using Targeted Lipid Nanoparticles
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From mass cytometry to cancer prognosis
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Down-regulation of LATS kinases alters p53 to promote cell migration
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Historic recollections: From polymers and proteins to autoimmunity and cancer.
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Tumor-derived osteopontin reprograms normal mammary fibroblasts to promote inflammation and tumor growth in breast cancer
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Folic acid-tagged protein nanoemulsions loaded with CORM-2 enhance the survival of mice bearing subcutaneous A20 lymphoma tumors
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Metabolic dysregulation in monogenic disorders and cancer - finding method in madness.
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c-Abl antagonizes the YAP oncogenic function
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Induction of the intestinal stem cell signature gene SMOC-2 is required for L1-mediated colon cancer progression
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Overshoot during phenotypic switching of cancer cell populations
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PYK2 integrates growth factor and cytokine receptors signaling and potentiates breast cancer invasion via a positive feedback loop
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Aptamer Targeting the ERBB2 Receptor Tyrosine Kinase for Applications in Tumor Therapy
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The nuclear translocation of ERK1/2 as an anticancer target
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Determination of optimal drug dose and light dose index to achieve minimally invasive focal ablation of localised prostate cancer using WST11-vascular-targeted photodynamic (VTP) therapy
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Photodynamic Quenched Cathepsin Activity Based Probes for Cancer Detection and Macrophage Targeted Therapy
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Single Exposure to near Roadway Particulate Matter Leads to Confined Inflammatory and Defense Responses: Possible Role of Metals
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Cancer immunotherapy: More is (much) better
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Combined local blood-brain barrier opening and systemic methotrexate for the treatment of brain tumors
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Cardiac glycosides induced toxicity in human cells expressing alpha 1-, alpha 2-, or alpha 3-isoforms of Na-K-ATPase
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The polyomavirus middle T-antigen oncogene activates the Hippo pathway tumor suppressor Lats in a Src-dependent manner
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Exercising 'veto' power to make haploidentical hematopoietic stem cell transplantation a safe modality for induction of immune tolerance
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MicroRNAs and Growth Factors: An Alliance Propelling Tumor Progression.
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Laparoscopic versus open liver resection for metastatic colorectal cancer
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Sensing Protein Surfaces with Targeted Fluorescent Receptors.
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mRNA-transfected Dendritic Cells Expressing Polypeptides That Link MHC-I Presentation to Constitutive TLR4 Activation Confer Tumor Immunity
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Haploidentical hematopoietic stem cell transplantation: state of art
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Sonicated Protein Fractions of Mycoplasma hyopneumoniae Induce Inflammatory Responses and Differential Gene Expression in a Murine Alveolar Macrophage Cell Line
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Tumor Suppressor Activity of Klotho in Breast Cancer is Revealed by Structure-function Analysis.
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Tumor-specific expression and detection of a CEST reporter gene
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EGF induces microRNAs that target suppressors of cell migration: miR-15b targets MTSS1 in breast cancer
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Tumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant
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Modeling and Predicting Optimal Treatment Scheduling Between the Antiangiogenic Drug Sunitinib and Irinotecan in Preclinical Settings
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Chromosome 7 gain and DNA hypermethylation at the HOXA10 locus are associated with expression of a stem cell related HOX-signature in glioblastoma
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Tumor-Associated and Disease-Associated Autoantibody Repertoires in Healthy Colostrum and Maternal and Newborn Cord Sera
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Recurrent inactivating RASA2 mutations in melanoma
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The Tyrosine Kinase c-Abl Promotes Homeodomain-interacting Protein Kinase 2 (HIPK2) Accumulation and Activation in Response to DNA Damage
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Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer
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Hepatitis B virus induces RNR-R2 expression via DNA damage response activation
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Extracellular matrix regulation of ErbB3 in a subset of wild-type BRAF/NRAS melanoma
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Pathway-based personalized analysis of breast cancer expression data
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Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression
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p53 orchestrates between normal differentiation and cancer
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ErbB3-ErbB2 Complexes as a Therapeutic Target in a Subset of Wild-type BRAF/NRAS Cutaneous Melanomas