All Publications

  • Single Instillation of Hypertonic Saline Immediately Following Transurethral Resection of Bladder Tumor for Recurrence Prevention –A Phase I Study

    Authors: Modai J., Kovalyonok A., Scherz A., Preise D., Avda Y., Shpunt I., Sasson K., Jaber M., Peretz Y., Croock R., Shilo Y., Ikher S., Lindner U. & Leibovici D. (2021), Bladder Cancer. 7, 2, p. 187-192
  • Identification of variable stages in murine pancreatic tumors by a multiparametric approach employing hyperpolarized 13C MRSI, 1H diffusivity and 1H T1 MRI

    Authors: Martinho R. P., Bao Q., Markovic S., Preise D., Sasson K., Agemy L., Scherz A. & Frydman L. (2021), NMR in Biomedicine. 34, 2, 4446
  • Conformational switches and redox properties of the colon cancer‐associated human lectin ZG16

    Authors: Javitt G., Kinzel A., Reznik N. & Fass D. (2021), The FEBS journal.
  • Decoding Cancer Biology One Cell at a Time

    Authors: Gonzalez Castro L. N., Tirosh I. & Suvà M. L. (2021), Cancer Discovery. 11, 4, p. 960-970
  • Learned Super Resolution Ultrasound for Improved Breast Lesion Characterization

    Authors: Bar-Shira O., Grubstein A., Rapson Y., Suhami D., Atar E., Peri-Hanania K., Rosen R. & Eldar Y. C. (2021),
  • Melanoma models for the next generation of therapies

    Authors: Patton E. E., Mueller K. L., Adams D. J., Anandasabapathy N., Aplin A. E., Bertolotto C., Bosenberg M., Ceol C. J., Chi P., Herlyn M., Holmen S. L., Karreth F. A., Kaufman C. K., Khan S., Kobold S., Leucci E., Levy C., Lombard D. B., Lund A. W., Marie K. L., Marine J. C., Marais R., McMahon M., Robles-Espinoza C. D., Ronai Z. A., Samuels Y., Soengas M. S., Villanueva J., Weeraratna A. T., White R. M., Yeh I., Zhu J., Zon L. I., Hurlbert M. S. & Merlino G. (2021), Cancer Cell.
  • Breast cancer is marked by specific, Public T-cell receptor CDR3 regions shared by mice and humans

    Authors: Gordin M., Philip H., Zilberberg A., Gidoni M., Margalit R., Clouser C., Adams K., Vigneault F., Cohen I. R., Yaari G. & Efroni S. (2021), PLoS Computational Biology. 17, 1, 1008486
  • Identification of bacteria-derived HLA-bound peptides in melanoma

    Authors: Kalaora S., Nagler A., Nejman D., Alon M., Barbolin C., Barnea E., Ketelaars S. L. C., Cheng K., Vervier K., Shental N., Bussi Y., Rotkopf R., Levy R., Benedek G., Trabish S., Dadosh T., Levin-Zaidman S., Geller L. T., Wang K., Greenberg P., Yagel G., Peri A., Fuks G., Bhardwaj N., Reuben A., Hermida L., Johnson S. B., Galloway-Peña J. R., Shropshire W. C., Bernatchez C., Haymaker C., Arora R., Roitman L., Eilam R., Weinberger A., Lotan-Pompan M., Lotem M., Levin Y., Lawley T. D., Adams D. J., Levesque M. P., Besser M. J., Schachter J., Golani O., Segal E., Ruppin E., Kvistborg P., Peterson S. N., Wargo J. A., Straussman R. & Samuels Y. (2021), Nature (London). 592, 7852, p. 138-143
  • CD84 is a regulator of the immunosuppressive microenvironment in multiple myeloma

    Authors: Lewinsky H., Gunes E. G., David K., Radomir L., Kramer M. P., Pellegrino B., Perpinial M., Chen J., He T. F., Mansour A. G., Teng K. Y., Bhattacharya S., Caserta E., Troadec E., Lee P., Feng M., Keats J., Krishnan A., Rosenzweig M., Yu J., Caligiuri M. A., Cohen Y., Shevetz O., Becker-Herman S., Pichiorri F., Rosen S. & Shachar I. (2021), JCI insight. 6, 4, 141683
  • Chromothripsis drives the evolution of gene amplification in cancer

    Authors: Shoshani O., Brunner S. F., Yaeger R., Ly P., Nechemia-Arbely Y., Kim D. H., Fang R., Castillon G. A., Yu M., Li J. S. Z., Sun Y., Ellisman M. H., Ren B., Campbell P. J. & Cleveland D. W. (2021), Nature (London). 591, 7848, p. 137-141
  • Persistent Inflammatory Stimulation Drives the Conversion of MSCs to Inflammatory CAFs That Promote Pro-Metastatic Characteristics in Breast Cancer Cells

    Authors: Rubinstein-Achiasaf L., Morein D., Ben-Yaakov H., Liubomirski Y., Meshel T., Elbaz E., Dorot O., Pichinuk E., Gershovits M., Weil M. & Ben-Baruch A. (2021), Cancers. 13, 6, 1472
  • P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression

    Authors: Yeini E., Ofek P., Pozzi S., Albeck N., Ben-Shushan D., Tiram G., Golan S., Kleiner R., Sheinin R., Israeli Dangoor S., Reich-Zeliger S., Grossman R., Ram Z., Brem H., Hyde T. M., Magod P., Friedmann-Morvinski D., Madi A. & Satchi-Fainaro R. (2021), Nature Communications. 12, 1912
  • The extracellular matrix protein agrin is essential for epicardial epithelial-to-mesenchymal transition during heart development

    Authors: Sun X., Malandraki-Miller S., Kennedy T., Bassat E., Klaourakis K., Zhao J., Gamen E., Vieira J. M., Tzahor E. & Riley P. R. (2021), Development (Cambridge). 148, 9
  • Alternative Splicing of the Inhibitory Immune Checkpoint Receptor SLAMF6 Generates a Dominant Positive Form, Boosting T-cell Effector Functions

    Authors: Hajaj E., Zisman E., Tzaban S., Merims S., Cohen J., Klein S., Frankenburg S., Sade-Feldman M., Tabach Y., Yizhak K., Navon A., Stepensky P., Hacohen N., Peretz T., Veillette A., Karni R., Eisenberg G. & Lotem M. (2021), Cancer immunology research. 9, 6, p. 637-650
  • Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles

    Authors: Tawil N., Bassawon R., Meehan B., Nehme A., Montermini L., Gayden T., De Jay N., Spinelli C., Chennakrishnaiah S., Choi D., Adnani L., Zeinieh M., Jabado N., Kleinman C. L., Witcher M., Riazalhosseini Y., Key N. S., Schiff D., Grover S. P., Mackman N., Couturier C. P., Petrecca K., Suvà M. L., Patel A., Tirosh I., Najafabadi H. & Rak J. (2021), Blood advances. 5, 6, p. 1682-1694
  • The context-specific roles of urea cycle enzymes in tumorigenesis

    Authors: Hajaj E., Sciacovelli M., Frezza C. & Erez A. (2021), Molecular Cell. 81, 18, p. 3749-3759
  • Diffusion Is Directional: Innovative Diffusion Tensor Imaging to Improve Prostate Cancer Detection

    Authors: Shenhar C., Degani H., Ber Y., Baniel J., Tamir S., Benjaminov O., Rosen P., Furman-Haran E. & Margel D. (2021), Diagnostics (Basel). 11, 3, 563
  • Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions

    Authors: Kolodkin-Gal D., Roitman L., Ovadya Y., Azazmeh N., Assouline B., Schlesinger Y., Kalifa R., Horwitz S., Khalatnik Y., Hochner-Ger A., Imam A., Demma J. A., Winter E., Benyamini H., Elgavish S., Khatib A. A., Meir K., Atlan K., Pikarsky E., Parnas O., Dor Y., Zamir G., Ben-Porath I. & Krizhanovsky V. (2021), Gut.
  • Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies

    Authors: Borenstein-Katz A., Warszawski S., Amon R., Eilon M., Cohen-Dvashi H., Leviatan Ben-Arye S., Tasnima N., Yu H., Chen X., Padler-Karavani V., Fleishman S. J. & Diskin R. (2021), Journal of Molecular Biology. 433, 15, 167099
  • The prospects of tumor chemosensitivity testing at the single-cell level

    Authors: Yang C., Yang C., Yarden Y., To K. K. & Fu L. (2021), Drug Resistance Updates. 54, 100741
  • Multiplexed Imaging Analysis of the Tumor-Immune Microenvironment Reveals Predictors of Outcome in Triple-Negative Breast Cancer

    Authors: Patwa A., Yamashita R., Long J., Angelo M., Yankielowicz-Keren L. & Rubin D. L. (2021), Communications Biology. 4, 852
  • Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models

    Authors: Marrocco I., Romaniello D., Vaknin I., Drago‐Garcia D., Oren R., Uribe M. L., Belugali Nataraj N., Ghosh S., Eilam R., Salame T., Lindzen M. & Yarden Y. (2021), EMBO Molecular Medicine. 13144
  • Clump sequencing exposes the spatial expression programs of intestinal secretory cells

    Authors: Manco R., Averbukh I., Porat Z., Bahar Halpern K., Amit I. & Itzkovitz S. (2021), Nature Communications. 12, p. -, 3074
  • Proteomic patterns associated with response to breast cancer neoadjuvant treatment

    Authors: Shenoy A., Belugali Nataraj N., Perry G., Loayza Puch F., Nagel R., Marin I., Balint N., Bossel N., Pavlovsky A., Barshack I., Kaufman B., Agami R., Yarden Y., Dadiani M. & Geiger T. (2021), Molecular Systems Biology. 16, 9, e9443
  • Reduced Lamin A/C Does Not Facilitate Cancer Cell Transendothelial Migration but Compromises Lung Metastasis

    Authors: Roncato F., Regev O., Feigelson S. W., Yadav S. K., Kaczmarczyk L., Levi N., Drago-Garcia D., Ovadia S., Kizner M., Addadi Y., Sabino J. C., Ovadya Y., de Almeida S. F., Feldmesser E., Gerlitz G. & Alon R. (2021), Cancers. 13, 10, 2383
  • Targeting nucleotide metabolism as the nexus of viral infections, cancer, and the immune response

    Authors: Ariav Y., Ch’ng J. H., Christofk H. R., Ron-Harel N. & Erez A. (2021), Science advances. 7, 21, eabg6165
  • The key roles of cancer stem cell-derived extracellular vesicles

    Authors: Su C., Zhang J., Yarden Y. & Fu L. (2021), Signal Transduction and Targeted Therapy. 6, 1, 109
  • EGFR in Cancer: Signaling Mechanisms, Drugs, and Acquired Resistance

    Authors: Uribe M. L., Marrocco I. & Yarden Y. (2021), Cancers. 13, 11, 2748
  • Conformation-Specific Inhibitory Anti-MMP-7 Monoclonal Antibody Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Chemotherapeutic Cell Kill

    Authors: Mohan V., Gaffney J. P., Solomonov I., Levin M., Klepfish M., Akbareian S., Grünwald B., Dym O., Eisenstein M., Yu K. H., Kelsen D. P., Krüger A., Edwards D. R. & Sagi I. (2021), Cancers. 13, 7, 1679
  • Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo

    Authors: Dubiella C., Pinch B. J., Koikawa K., Zaidman D., Poon E., Manz T. D., Nabet B., He S., Resnick E., Rogel A., Langer E. M., Daniel C. J., Seo H., Chen Y., Adelmant G., Sharifzadeh S., Ficarro S. B., Martins da Costa B., Jamin Y., Zimmerman M. W., Lian X., Kibe S., Kozono S., Doctor Z. M., Browne C. M., Yang A., Stoler-Barak L., Shah R. B., Vangos N. E., Geffken E. A., Oren R., Koide E., Sidi S., Shulman Z., Wang C., Marto J. A., Dhe-Paganon S., Look T., Zhou X. Z., Lu K. P., Sears R. C., Chesler L., Gray N. S. & London N. (2021), Nature Chemical Biology. 17, 9, p. 954-963
  • Clinical Proteomics of Metastatic Melanoma Reveals Profiles of Organ Specificity and Treatment Resistance

    Authors: Beck L., Harel M., Yu S., Markovits E., Boursi B., Markel G. & Geiger T. (2021), Clinical Cancer Research. 27, 7, p. 2074-2086
  • Biological and therapeutic implications of a unique subtype of NPM1 mutated AML

    Authors: Mer A. S., Heath E. M., Madani Tonekaboni S. A., Dogan-Artun N., Nair S. K., Murison A., Garcia-Prat L., Shlush L., Hurren R., Voisin V., Bader G. D., Nislow C., Rantalainen M., Lehmann S., Gower M., Guidos C. J., Lupien M., Dick J. E., Minden M. D., Schimmer A. D. & Haibe-Kains B. (2021), Nature Communications. 12, 1054
  • Roles for growth factors and mutations in metastatic dissemination

    Authors: Nataraj N. B., Marrocco I. & Yarden Y. (2021), Biochemical Society Transactions. BST2021004
  • A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma

    Authors: Choi J. E., Sebastian C., Ferrer C. M., Lewis C. A., Sade-Feldman M., LaSalle T., Gonye A., Lopez B. G., Abdelmoula W. M., Regan M. S., Cetinbas M., Pascual G., Wojtkiewicz G. R., Silveira G. G., Boon R., Ross K. N., Tirosh I., Saladi S. V., Ellisen L. W., Sadreyev R. I., Benitah S. A., Agar N. Y., Hacohen N. & Mostoslavsky R. (2021), Nature metabolism. 3, 2, p. 182-195
  • The evolution of leukaemia from pre‐leukaemic and leukaemic stem cells

    Authors: Shlush L. I. & Feldman T. (2021), Journal of Internal Medicine.
  • Tumour inflammation signature and expression of S100A12 and HLA class I improve survival in HPV-negative hypopharyngeal cancer

    Authors: Mints M., Landin D., Näsman A., Mirzaie L., Ursu R. G., Zupancic M., Marklund L., Dalianis T., Munck-Wikland E. & Ramqvist T. (2021), Scientific Reports. 11, 1782
  • MT1 and MT2 melatonin receptors play opposite roles in brain cancer progression

    Authors: Kinker G. S., Ostrowski L. H., Ribeiro P. A., Chanoch R., Muxel S. M., Tirosh I., Spadoni G., Rivara S., Martins V. R., Santos T. G., Markus R. P. & Fernandes P. A. (2021), Journal of Molecular Medicine. 2, p. 289-301
  • Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis

    Authors: Beyaz S., Chung C., Mou H., Bauer-Rowe K. E., Xifaras M. E., Ergin I., Dohnalova L., Biton M., Shekhar K., Eskiocak O., Papciak K., Ozler K., Almeqdadi M., Yueh B., Fein M., Annamalai D., Valle-Encinas E., Erdemir A., Dogum K., Shah V., Alici-Garipcan A., Meyer H. V., Özata D. M., Elinav E., Kucukural A., Kumar P., McAleer J. P., Fox J. G., Thaiss C. A., Regev A., Roper J., Orkin S. H. & Yilmaz Ö. H. (2021), Cell Stem Cell.
  • NASH limits anti-tumour surveillance in immunotherapy-treated HCC

    Authors: Pfister D., Núñez N. G., Pinyol R., Govaere O., Pinter M., Szydlowska M., Gupta R., Qiu M., Deczkowska A., Weiner A., Müller F., Sinha A., Friebel E., Engleitner T., Lenggenhager D., Moncsek A., Heide D., Stirm K., Kosla J., Kotsiliti E., Leone V., Dudek M., Yousuf S., Inverso D., Singh I., Teijeiro A., Castet F., Montironi C., Haber P. K., Tiniakos D., Bedossa P., Cockell S., Younes R., Vacca M., Marra F., Schattenberg J. M., Allison M., Bugianesi E., Ratziu V., Pressiani T., D'Alessio A., Personeni N., Rimassa L., Daly A. K., Scheiner B., Pomej K., Kirstein M. M., Vogel A., Peck-Radosavljevic M., Hucke F., Finkelmeier F., Waidmann O., Trojan J., Schulze K., Wege H., Koch S., Weinmann A., Bueter M., Rössler F., Siebenhüner A., Dosso S. D., Mallm J., Umansky V., Jugold M., Luedde T., Schietinger A., Schirmacher P., Emu B., Augustin H. G., Billeter A., Müller-Stich B., Kikuchi H., Duda D. G., Kütting F., Waldschmidt D., Ebert M. P., Rahbari N., Mei H. E., Schulz A. R., Ringelhan M., Malek N., Spahn S., Bitzer M., Ruiz de Galarreta M., Lujambio A., Dufour J., Marron T. U., Kaseb A., Kudo M., Huang Y., Djouder N., Wolter K., Zender L., Marche P. N., Decaens T., Pinato D. J., Rad R., Mertens J. C., Weber A., Unger K., Meissner F., Roth S., Jilkova Z. M., Claassen M., Anstee Q. M., Amit I., Knolle P., Becher B., Llovet J. M. & Heikenwalder M. (2021), Nature (London).
  • ACK1 is dispensable for development, skin tumor formation, and breast cancer cell proliferation

    Authors: Brandao R., Kwa M. Q., Yarden Y. & Brakebusch C. (2021), FEBS Open Bio. 11, 6, p. 1579-1592
  • Proteolysis Targeting Chimeras for BTK Efficiently Inhibit B-Cell Receptor Signaling and Can Overcome Ibrutinib Resistance in CLL Cells

    Authors: Shorer Arbel Y., Katz B., Gabizon R., Shraga A., Bronstein Y., Kamdjou T., Globerson Levin A., Perry C., Avivi I., London N. & Herishanu Y. (2021), Frontiers in Oncology. 11, 646971
  • Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma

    Authors: Risom T., Glass D., Liu C., Rivero-Gutiérrez B., Baranski A., McCaffrey E., Greenwald N. F., Kagel A., Strand S., Varma S., Kong A., Yankielowicz-Keren L., Srivastava S., Zhu C., Khair Z., Veis D., Deschryver K., Vennam S., Maley C., Hwang E., Marks J., Bendall S. C., Colditz G., West R. & Angelo M. (2021), BioRxiv.
  • The evolutionarily conserved long non-coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms

    Authors: Mather R. L., Parolia A., Carson S. E., Venalainen E., Roig-Carles D., Jaber M., Chu S., Alborelli I., Wu R., Lin D., Nabavi N., Jachetti E., Colombo M. P., Xue H., Pucci P., Ci X., Hawkes C., Li Y., Pandha H., Ulitsky I., Marconett C., Quagliata L., Jiang W., Romero I., Wang Y. & Crea F. (2021), Molecular Oncology.
  • Decoupling epithelial-mesenchymal transitions from stromal profiles by integrative expression analysis

    Authors: Tyler M. & Tirosh I. (2021), Nature Communications. 12, 1, 2592
  • Treatment results from a phase I study of WST11 phototherapy (VTP) for upper tract urothelial carcinoma

    Authors: Nogueira L., Tracey A., Alvim R. G., Reisz P., Sjoberg D. D., Demac Q., Benfante N., Nagar K., Thomas J., Cheng J., Kim K., Solit D. B., Scherz A. J. & Coleman J. (2021), Journal of Clinical Oncology. 39, 6_suppl, p. 460-460
  • The Collagen-Modifying Enzyme PLOD2 Is Induced and Required during L1-Mediated Colon Cancer Progression

    Authors: Cheriyamundath S., Kumar A., Gavert N., Brabletz T. & Ben-Ze’ev A. (2021), International Journal of Molecular Sciences. 22, 7, 3552
  • Accelerating AXL targeting for TNBC therapy

  • The AXL-PYK2-PKCα axis as a nexus of stemness circuits in TNBC

    Authors: Khera L., Vinik Y., Maina F. & Lev S. (2021), Life Science Alliance. 4, 6, e202000985
  • Putative Blood Somatic Mutations in Post-Traumatic Stress Disorder-Symptomatic Soldiers: High Impact of Cytoskeletal and Inflammatory Proteins

    Authors: Sragovich S., Gershovits M., Lam J. C., Li V. O. & Gozes I. (2021), Journal of Alzheimer's Disease. 79, 4, p. 1723-1734
  • Neoadjuvant vascular-targeted photodynamic therapy improves survival and reduces recurrence and progression in a mouse model of urothelial cancer

    Authors: Rosenzweig B., Corradi R. B., Budhu S., Alvim R., Recabal P., La Rosa S., Somma A., Monette S., Scherz A., Kim K. & Coleman J. A. (2021), Scientific Reports. 11, 1, 4842
  • Transient genomic instability drives tumorigenesis through accelerated clonal evolution

    Authors: Shoshani O., Bakker B., de Haan L., Tijhuis A., Wang Y., Kim D. H., Maldonado M., Demarest M., Artates J., Zhengyu O., Mark A., Wardenaar R., Sasik R., Spierings D., Vitre B., Fisch K., Foijer F. & Cleveland D. W. (2021), GENES & DEVELOPMENT. 35, 15-16, p. 1093-1108
  • Recurrent deletions in clonal hematopoiesis are driven by microhomology-mediated end joining

    Authors: Feldman T., Bercovich A., Moskovitz Y., Chapal-Ilani N., Mitchell A., Medeiros J. J. F., Biezuner T., Kaushansky N., Minden M. D., Gupta V., Milyavsky M., Livneh Z., Tanay A. & Shlush L. I. (2021), Nature Communications. 12, 1, 2455
  • Meningeal lymphoid structures are activated under acute and chronic spinal cord pathologies

    Authors: Cohen M., Giladi A., Raposo C., Zada M., Li B., Ruckh J., Deczkowska A., Mohar B., Shechter R., Lichtenstein R. G., Amit I. & Schwartz M. (2021), Life Science Alliance. 4, 1, 202000907
  • Aberrant transcriptional and post-transcriptional regulation of SPAG5, a YAP-TAZ-TEAD downstream effector, fuels breast cancer cell proliferation

    Authors: Canu V., Donzelli S., Sacconi A., Lo Sardo F., Pulito C., Bossel N., Di Benedetto A., Muti P., Botti C., Domany E., Bicciato S., Strano S., Yarden Y. & Blandino G. (2021), Cell Death and Differentiation. 28, 5, p. 1493-1511
  • Proteogenomics of glioblastoma associates molecular patterns with survival

    Authors: Yanovich-Arad G., Ofek P., Yeini E., Mardamshina M., Danilevsky A., Shomron N., Grossman R., Satchi-Fainaro R. & Geiger T. (2021), Cell reports (Cambridge). 34, 9, 108787
  • DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation

    Authors: Batra R. N., Lifshitz A., Vidakovic A. T., Chin S., Sati-Batra A., Sammut S., Provenzano E., Ali H. R., Dariush A., Bruna A., Murphy L., Purushotham A., Ellis I., Green A., Garrett-Bakelman F. E., Mason C., Melnick A., Aparicio S. A. J. R., Rueda O. M., Caldas C. & Tanay A. (2021), Nature Communications. 12, 1, 5406
  • Immunoediting role for major vault protein in apoptotic signaling induced by bacterial N-acyl homoserine lactones

    Authors: Rayo J., Gregor R., Jacob N. T., Dandela R., Dubinsky L., Yashkin A., Aranovich A., Thangaraj M., Ernst O., Barash E., Malitsky S., Florea B. I., Krom B. P., Wiemer E. A. C., Kickhoefer V. A., Rome L. H., Mathison J. C., Kaufmann G. F., Overkleeft H. S., Cravatt B. F., Zor T., Janda K. D., Ulevitch R. J., Kravchenko V. V. & Meijler M. M. (2021), Proceedings of the National Academy of Sciences - PNAS. 118, 12, e201252911
  • Learned Super Resolution Ultrasound for Improved Breast Lesion Characterization

    Authors: Bar-Shira O., Grubstein A., Rapson Y., Suhami D., Atar E., Peri Hanania K., Rosen R. & Eldar Y. (2021),
  • MEK inhibition reverses aberrant signaling in melanoma cells through reorganization of NRas and BRAF in self nano-clusters

    Authors: Yakovian O., Sajman J., Arafeh R., Neve-Oz Y., Alon M., Samuels Y. & Sherman E. (2021), Cancer research (Chicago, Ill.). 81, 5, p. 1279-1292
  • Microtubule destabilization is a critical checkpoint of chemotaxis and transendothelial migration in melanoma cells but not in T cells

    Authors: Roncato F., Regev O., Yadav S. K. & Alon R. (2021), Cell Adhesion & Migration. 15, 1, p. 166-179
  • P32-specific CAR T cells with dual antitumor and antiangiogenic therapeutic potential in gliomas

    Authors: Rousso-Noori L., Mastandrea I., Talmor S., Waks T., Globerson Levin A., Haugas M., Teesalu T., Alvarez-Vallina L., Eshhar Z. & Friedmann-Morvinski D. (2021), Nature Communications. 12, 1, 3615
  • Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis

    Authors: Mathewson N. D., Ashenberg O., Tirosh I., Gritsch S., Perez E. M., Marx S., Jerby-Arnon L., Chanoch-Myers R., Hara T., Richman A. R., Ito Y., Pyrdol J., Friedrich M., Schumann K., Poitras M. J., Gokhale P. C., Gonzalez Castro L. N., Shore M. E., Hebert C. M., Shaw B., Cahill H. L., Drummond M., Zhang W., Olawoyin O., Wakimoto H., Rozenblatt-Rosen O., Brastianos P. K., Liu X. S., Jones P. S., Cahill D. P., Frosch M. P., Louis D. N., Freeman G. J., Ligon K. L., Marson A., Chiocca E. A., Reardon D. A., Regev A., Suvà M. L. & Wucherpfennig K. W. (2021), Cell. 184, 5, p. 1281-1298
  • SCIRT lncRNA Restrains Tumorigenesis by Opposing Transcriptional Programs of Tumor-Initiating Cells

    Authors: Zagorac S., de Giorgio A., Dabrowska A., Kalisz M., Casas-Vila N., Cathcart P., Yiu A., Ottaviani S., Degani N., Lombardo Y., Tweedie A., Nissan T., Vance K. W., Ulitsky I., Stebbing J. & Castellano L. (2021), Cancer Research. 81, 3, p. 580-593
  • PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR

    Authors: Ghosh S., Nataraj N. B., Noronha A., Patkar S., Sekar A., Mukherjee S., Winograd-Katz S., Kramarski L., Verma A., Lindzen M., Garcia D. D., Green J., Eisenberg G., Gil-Henn H., Basu A., Lender Y., Weiss S., Oren M., Lotem M., Geiger B., Ruppin E. & Yarden Y. (2021), Cell reports (Cambridge). 35, 8, 109181
  • Intratumoral heterogeneity in cancer progression and response to immunotherapy

    Authors: Vitale I., Shema E., Loi S. & Galluzzi L. (2021), Nature Medicine. 27, 2, p. 212-224
  • Deuterium MRSI characterizations of glucose metabolism in orthotopic pancreatic cancer mouse models

    Authors: Markovic S., Roussel T., Agemy L., Sasson K., Preise D., Scherz A. & Frydman L. (2021), NMR in Biomedicine. e4569
  • Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression

    Authors: Barnabas G. D., Lee J. S., Shami T., Harel M., Beck L., Selitrennik M., Jerby-Arnon L., Erez N., Ruppin E. & Geiger T. (2021), Cancer research (Chicago, Ill.). 81, 6, p. 1443-1456
  • Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation

    Authors: Wu Y., Chou T., Young L., Hsieh F., Pan H., Mo S., Brown S. B., Chen R., Kimchi A. & Lai M. (2020), Cell Death & Disease. 11, 305
  • The microbiome and cytosolic innate immune receptors

    Authors: Liwinski T., Zheng D. & Elinav E. (2020), Immunological Reviews. 1, p. 207-224
  • Myotubularin-related protein 7 activates peroxisome proliferator-activated receptor-gamma

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