-
Survivorship Data in Prostate Cancer: Where Are We and Where Do We Need To Be?
-
Real-Time Model-Based Quantitative Ultrasound and Radar
-
Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma
-
Cancer cell states: Lessons from ten years of single-cell RNA-sequencing of human tumors
-
Potent antitumor activity of anti-HER2 antibody-topoisomerase I inhibitor conjugate based on self-immolative dendritic dimeric-linker
-
Recycled melanoma-secreted melanosomes regulate tumor-associated macrophage diversification
-
IL-23 stabilizes an effector Treg cell program in the tumor microenvironment
-
Longitudinal single-cell data informs deterministic modelling of inflammatory bowel disease
-
Unlocking the Role of Age-Related Changes to Fibroblasts in Pancreatic Cancer
-
ASS1 metabolically contributes to the nuclear and cytosolic p53-mediated DNA damage response
-
CAF-induced physical constraints controlling T cell state and localization in solid tumours
-
Dual targeting of histone deacetylases and myc as potential treatment strategy for h3- k27m pediatric gliomas
-
HSF1 renders NK cells too stressed to respond
-
Meet the authors: Guy Zoltsman and Rina Rosenzweig
-
Retinoic acid, an essential component of the roof plate organizer, promotes the spatiotemporal segregation of dorsal neural fates
-
Exploiting Urea-Carboxylate Synthon for Designing Supramolecular Topical Hydrogel via Simple Organic Salt Formation: Synthesis, Crystal Structures, and Anticancer Behavior against Melanoma B16-F10 Cells
-
Measuring and modeling the dynamics of mitotic error correction
-
Embracing cancer complexity: Hallmarks of systemic disease
-
Human MAIT cells inhibit alloreactive T cell responses and protect against acute graft-versus-host disease
-
Improving Microstructural Estimation in Time-Dependent Diffusion MRI With a Bayesian Method
-
Real-Time Quantitative Ultrasound and Radar Medical Imaging
-
The tumor-driven antibody-mediated immune response in cancer
-
Microbiome modulation of antigen presentation in tolerance and inflammation
-
Cell-penetrating peptide and cationic liposomes mediated siRNA delivery to arrest growth of chronic myeloid leukemia cells in vitro
-
Loss-of-function cancer-linked mutations in the EIF4G2 non-canonical translation initiation factor
-
Mutant IDH inhibitors induce lineage differentiation in IDH-mutant oligodendroglioma
-
ARTS and small-molecule ARTS mimetics upregulate p53 levels by promoting the degradation of XIAP
-
Hypoxia-dependent recruitment of error-prone DNA polymerases to genome replication
-
Emergent seesaw oscillations during cellular directional decision-making
-
Elemental Characterization of Ambient Particulate Matter for a Globally Distributed Monitoring Network: Methodology and Implications
-
Acute Toxicity and Early Prostate Specific Antigen Response After Two-Fraction Stereotactic Radiation Therapy for Localized Prostate Cancer Using Peri-Rectal Spacing Initial Report of the SABR-Dual Trial
-
Cancer Hallmarks: Piecing the Puzzle Together
-
Health impacts of biomass burning aerosols: Relation to oxidative stress and inflammation
-
Single-cell atlas of the human brain vasculature across development, adulthood and disease
-
Crosslinking of Ly6a metabolically reprograms CD8 T cells for cancer immunotherapy
-
A unique chaperoning mechanism in class A JDPs recognizes and stabilizes mutant p53
-
FcγRIIB is an immune checkpoint limiting the activity of Treg-targeting antibodies in the tumor microenvironment
-
Targeting of mutant-p53 and MYC as a novel strategy to inhibit oncogenic SPAG5 activity in triple negative breast cancer
-
Identification of gene fusions associated with amyotrophic lateral sclerosis
-
Genomic linkages dictate cancer evolution
-
Comparative study of immune response to local tumor destruction modalities in a murine breast cancer model
-
From the Inside Out: Exposing the Roles of Urea Cycle Enzymes in Tumors and Their Micro and Macro Environments
-
Targeting Tumor-Associated Sialic Acids Using Chimeric Switch Receptors Based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells
-
Molecular mechanisms underlying the modulation of T-cell proliferation and cytotoxicity by immobilized CCL21 and ICAM1
-
Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity
-
Medical Image Segmentation Using Directional Window Attention
-
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
-
Update on current and new potential immunotherapies in breast cancer, from bench to bedside
-
The role of CCL2/CCR2 axis in cancer and inflammation: The next frontier in nanomedicine
-
PIONEER big data platform for prostate cancer: lessons for advancing future real-world evidence research
-
Molecular imaging of tumor metabolism: Insight from pyruvate- and glucose-based deuterium MRI studies
-
Converging survival trends in non-small cell lung cancer patients with and without brain metastasis receiving state-of-the-art treatment
-
A hybrid epithelial/mesenchymal state in head and neck cancer: A biomarker for survival with differential prognosis by self-reported race
-
CD84 as a therapeutic target for breaking immune tolerance in triple-negative breast cancer
-
The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
-
Mapping the tumor stress network reveals dynamic shifts in the stromal oxidative stress response
-
Protocol for assessing murine cell doublet engagement and subsequent effects using flow cytometry and imaging flow cytometry
-
Site-specific serology unveils cross-reactive monoclonal antibodies targeting influenza A hemagglutinin epitopes
-
Generation of Non-Alloreactive Antiviral Central Memory CD8 Human Veto T Cells for Cell Therapy
-
Motility driven glassy dynamics in confluent epithelial monolayers
-
A snapshot into the transcriptomic landscape of apoptosis and ferroptosis in cancer
-
The oncogenic axis YAP/MYC/EZH2 impairs PTEN tumor suppression activity enhancing lung tumorigenicity
-
Fc-optimized checkpoint antibodies for cancer immunotherapy
-
Detecting bone lesions in X-ray under diverse acquisition conditions
-
A microbial iron fist to fight tumors
-
Exploring the role of artificial intelligence, large language models: Comparing patient-focused information and clinical decision support capabilities to the gynecologic oncology guidelines: Comparing patient-focused information and clinical decision support capabilities to the gynecologic oncology guidelines
-
Bispecific dendritic-T cell engager potentiates anti-tumor immunity
-
Guidelines for minimal information on cellular senescence experimentation in vivo
-
Sonodynamic Therapy for HER2+ Breast Cancer with Iodinated Heptamethine CyanineTrastuzumab Conjugate
-
Structureactivity relationship study of small-molecule inhibitor of Atg12-Atg3 proteinprotein interaction
-
Programming a Ferroptosis-to-Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy
-
Fast T1 mapping MRI in preclinical and clinical settings using subspace-constrained joint-domain reconstructions
-
p16-dependent increase of PD-L1 stability regulates immunosurveillance of senescent cells
-
Oncogenic Calreticulin Induces Immune Escape by Stimulating TGFβ Expression and Regulatory T-cell Expansion in the Bone Marrow Microenvironment
-
Defining myeloid-derived suppressor cells
-
Aberrant nuclei with amplified DNA in cancer
-
Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer
-
High-throughput identification of repurposable neuroactive drugs with potent anti-glioblastoma activity
-
Modeling T cell temporal response to cancer immunotherapy rationalizes development of combinatorial treatment protocols
-
Dasatinib induces endothelial dysfunction leading to impaired recovery from ischaemia
-
Sortilin in Biliary Epithelial Cells Promotes Ductular Reaction and Fibrosis during Cholestatic Injury
-
p53: A tale of complexity and context
-
Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ
-
Myotubularin-related-protein-7 inhibits mutant (G12V) K-RAS by direct interaction
-
CD81-guided heterologous EVs present heterogeneous interactions with breast cancer cells
-
Mutant p53 reactivation restricts the protumorigenic consequences of wild type p53 loss of heterozygosity in Li-Fraumeni syndrome patient-derived fibroblasts
-
Integrative spatial analysis reveals a multi-layered organization of glioblastoma
-
ATF3 characterizes aggressive drug-tolerant persister cells in HGSOC
-
Signaling lymphocytic activation molecule family receptors as potential immune therapeutic targets in solid tumors
-
Loss of EIF4G2 mediates aggressiveness in distinct human endometrial cancer subpopulations with poor survival outcome in patients
-
Melanoma and microbiota: Current understanding and future directions
-
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods
-
Computational pipeline predicting cell death suppressors as targets for cancer therapy
-
Non-canonical BIM-regulated energy metabolism determines drug-induced liver necrosis
-
Tumor cells express and maintain HMGB1 in the reduced isoform to enhance CXCR4-mediated migration
-
Targeting SRSF2 mutations in leukemia with RKI-1447: A strategy to impair cellular division and nuclear structure
-
Glucagon-like peptide-1 analogs activate AMP kinase leading to reversal of the Warburg metabolic switch in breast cancer cells
-
Keeping IPMNs in Check: A Novel Role for the Transcription Factor NKX6-2 in Preserving an Indolent Cell Identity in Pancreatic Cystic Lesions
-
The MAPK Signaling Cascades
-
PRC2-independent actions of H3.3K27M in embryonic stem cell differentiation
-
Cell lipid droplet heterogeneity and altered biophysical properties induced by cell stress and metabolic imbalance
-
In Synergy: Optimizing CAR T Development and Personalizing Patient Care Using Single-Cell Technologies
-
Polarization and motility of one-dimensional multi-cellular trains
-
Prevalence of MRI lesions in men responding to a GP-led invitation for a prostate health check: A prospective cohort study
-
Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma
-
A non-antibiotic-disrupted gut microbiome is associated with clinical responses to CD19-CAR-T cell cancer immunotherapy
-
Clonal heterogeneity in ER+ breast cancer reveals the proteasome and PKC as potential therapeutic targets
-
High-sensitivity deuterium metabolic MRI differentiates acute pancreatitis from pancreatic cancers in murine models
-
A clinical evaluation of an ex vivo organ culture system to predict patient response to cancer therapy
-
Quantification of Invadopodia Formation and Matrix Degradation Activity
-
Early death after a diagnosis of metastatic solid cancerraising awareness and identifying risk factors from the SEER database
-
Actin Filaments Couple the Protrusive Tips to the Nucleus through the I-BAR Domain Protein IRSp53 during the Migration of Cells on 1D Fibers
-
Characterisation of knowledge of cancer, illness perceptions and their interaction among high-school students
-
Deoxyhypusine hydroxylase: A novel therapeutic target differentially expressed in short-term vs long-term survivors of glioblastoma
-
Spatial profiling technologies illuminate the tumor microenvironment
-
C-terminal domain dimerization in yeast Hsp90 is moderately modulated by the other domains
-
Definition of the contribution of an Osteopontin-producing CD11c+ microglial subset to Alzheimers disease
-
Phase II trial of hypomethylating agent combined with nivolumab for acute myeloid leukaemia relapse after allogeneic haematopoietic cell transplantationImmune signature correlates with response
-
Author Correction: Breast cancer plasticity is restricted by a LATS1-NCOR1 repressive axis (doi 10.1038/s41467-022-34863-9 , 28 Nov, 2022)
-
Distinct spatiotemporal features of microglia and monocyte-derived macrophages in glioma
-
L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
-
Identifying a selective inhibitor of autophagy that targets ATG12-ATG3 protein-protein interaction
-
Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture
-
Large-Scale Immunopeptidome Analysis Reveals Recurrent Posttranslational Splicing of Cancer- and Immune-Associated Genes
-
Arterial Thromboembolism in Patients With AF and CHA2DS2-VASc Score 0-2 With and Without Cancer
-
Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours
-
Shearing of surface mucin saps tumor cell strength
-
Probing lipids relaxation times in breast cancer using magnetic resonance spectroscopic fingerprinting
-
Proteomic signature for detection of high-grade ovarian cancer in germline BRCA mutation carriers
-
Neoantigens in cancer immunotherapy: quantity vs. quality
-
Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling
-
MYC Induces Immunotherapy and IFNg Resistance Through Downregulation of JAK2
-
MiR-142-3p is a Critical Modulator of TNF-mediated Neuronal Toxicity in Multiple Sclerosis
-
Nanodot zirconium trisulfide based highly efficient biosensor for early diagnosis of lung cancer
-
Redefining metalloproteases specificity through network proteolysis
-
Green Synthesis of Silver Nanoparticles Using the Leaf Extract of the Medicinal Plant, Uvaria narum and Its Antibacterial, Antiangiogenic, Anticancer and Catalytic Properties
-
Chemically programmable bacterial probes for the recognition of cell surface proteins
-
gUMI-BEAR, a modular, unsupervised population barcoding method to track variants and evolution at high resolution
-
Compromised Blood-Brain Barrier Junctions Enhance Melanoma Cell Intercalation and Extravasation
-
Mutually communicated model based on multi-parametric MRI for automated segmentation and classification of prostate cancer
-
Design, Synthesis, and Structural Insights of a Series of Zn(II)-NSAID Based Coordination Complex Derived Metallogels and Their Plausible Applications in Self Drug Delivery
-
RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer
-
Targeted delivery of tumor necrosis factor in combination with CCNU induces a T cell-dependent regression of glioblastoma
-
RelaxationDiffusion T2ADC Correlations in Breast Cancer Patients: A Spatiotemporally Encoded 3T MRI Assessment
-
The microbial genotoxin colibactin exacerbates mismatch repair mutations in colorectal tumors
-
EMSY stabilization in KEAP1-mutant lung cancer disrupts genome stability and type I interferon signaling
-
It takes two to tango: the role of tumor-associated macrophages in T cell-directed immune checkpoint blockade therapy
-
Spectrum of Response to Platinum and PARP Inhibitors in Germline BRCAAssociated Pancreatic Cancer in the Clinical and Preclinical Setting
-
Multiplexed, single-molecule, epigenetic analysis of plasma-isolated nucleosomes for cancer diagnostics
-
Unanswered questions in prostate cancer - findings of an international multi-stakeholder consensus by the PIONEER consortium
-
Liver receptor homolog-1 (NR5A2) orchestrates hepatic inflammation and TNF-induced cell death
-
DNA methylation landscape of tumor-associated macrophages reveals pathways, transcription factors, and prognostic value relevant to triple-negative breast cancer patients
-
Clonal hematopoiesis in the donor does not adversely affect long-term outcomes following allogeneic hematopoietic stem cell transplantation: result from a 13-year follow-up
-
The tumor microenvironment shows a hierarchy of cell-cell interactions dominated by fibroblasts
-
CAR-T Cell Therapy and the Gut Microbiota
-
The landscape of T cell antigens for cancer immunotherapy
-
Cellular states are coupled to genomic and viral heterogeneity in HPV-related oropharyngeal carcinoma
-
Immunometabolism at the crossroads of obesity and cancera Keystone Symposia report
-
Intracellular bacteria in cancerprospects and debates
-
Functional Impact of Protein-RNA Variation in Clinical Cancer Analyses
-
Depleting the 19S proteasome regulatory PSMD1 subunit as a cancer therapy strategy
-
A Novel Modality Enables New Evidence-Based Individual Risk Stratification That Can Potentially Lead to Decisive Management and Treatment Decisions in Prostate Cancer
-
The prognostic value of beta-1 blockers in patients with non-small-cell lung carcinoma treated with pembrolizumab
-
Resistance of Lung Cancer to EGFR-Specific Kinase Inhibitors: Activation of Bypass Pathways and Endogenous Mutators
-
Deuterium imaging of the Warburg effect at sub-millimolar concentrations by joint processing of the kinetic and spectral dimensions
-
Folylpolyglutamate synthetase mRNA G-quadruplexes regulate its cell protrusion localization and enhance a cancer cell invasive phenotype upon folate repletion
-
UV irradiation remodels the specificity landscape of transcription factors
-
A natural goldmine of binding proteins and soluble receptors simplified their translation to blockbuster drugs, all in one decade
-
Glioma synapses recruit mechanisms of adaptive plasticity
-
Circadian regulation of liver function: from molecular mechanisms to disease pathophysiology
-
Deciphering the involvement of the Hippo pathway co-regulators, YAP/TAZ in invadopodia formation and matrix degradation
-
Methyl-CpG binding domain 2 (Mbd2) is an epigenetic regulator of autism-risk genes and cognition
-
Fungi and cancer
-
Phage-display immunoprecipitation sequencing of the antibody epitope repertoire in inflammatory bowel disease reveals distinct antibody signatures
-
Spatial and temporal mapping of breast cancer lung metastases identify TREM2 macrophages as regulators of the metastatic boundary
-
A Highly Sensitive Flow Cytometric Approach to Detect Rare Antigen-Specific T Cells: Development and Comparison to Standard Monitoring Tools
-
The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC
-
Paradoxical activation of chronic lymphocytic leukemia cells by ruxolitinib in vitro and in vivo
-
Cellular and metabolic characteristics of pre-leukemic hematopoietic progenitors with GATA2 haploinsufficiency
-
Unifying design principles of endocrine gland mass and its regulatory circuits
-
Actin-dependent astrocytic infiltration is a key step for axon defasciculation during remodeling
-
Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy
-
PYK2, a hub of signaling networks in breast cancer progression
-
Identification of Lung Cancer Biomarkers by Nanosensors Based on Titanium Carbide (Ti3C2Tx) MXenes
-
Computational design of BclxL inhibitors that target transmembrane domain interactions
-
Apoptotic cell death in diseaseCurrent understanding of the NCCD 2023
-
Immune escape of colorectal tumours via local LRH-1/Cyp11b1-mediated synthesis of immunosuppressive glucocorticoids
-
TAZ facilitates breast tumor growth by promoting an immune-suppressive tumor microenvironment
-
Hepatitis C virus infects and perturbs liver stem cells
-
A single-molecule liquid biopsy for cancer diagnosis
-
Tackling tumor complexity with single-cell proteomics
-
Clinical trial links oncolytic immunoactivation to survival in glioblastoma
-
Early Infiltration of Innate Immune Cells to the Liver Depletes HNF4α and Promotes Extrahepatic Carcinogenesis
-
Targeting ribosome biogenesis reinforces ERK-dependent senescence in pancreatic cancer
-
Immune checkpoint inhibition mediated with liposomal nanomedicine for cancer therapy
-
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis
-
p21 facilitates chronic lung inflammation via epithelial and endothelial cells
-
The C-terminal tail of CSNAP attenuates the CSN complex
-
Prostate lesions characterization using diffusion-weighted spatiotemporal encoded MRI: Feasibility and initial assessment
-
How Well do Polygenic Risk Scores Identify Men at High Risk for Prostate Cancer? Systematic Review and Meta-Analysis
-
An Increase in Mucin2 Expression Is Required for Colon Cancer Progression Mediated by L1
-
Cholesterol 24-hydroxylase at the choroid plexus contributes to brain immune homeostasis
-
Integrative study of whole exome variation and expression in gingivo-buccal oral squamous cell carcinoma revealed alteration in TLR-activated MAP-Kinase signalling
-
TRAF3 suppression encourages B cell recruitment and prolongs survival of microbiome-intact mice with ovarian cancer
-
Clonal evolution of leukemia from G6PD studies
-
Trapping all ERBB ligands decreases pancreatic lesions in a murine model of pancreatic ductal adenocarcinoma
-
Insights into the co-evolution of epithelial cells and fibroblasts in the esophageal tumor microenvironment
-
Drugging p53 in cancer: one protein, many targets
-
The Actin Network Interfacing Diverse Integrin-Mediated Adhesions
-
Breast Cancer-Secreted Factors Promote Lung Metastasis by Signaling Systemically to Induce a Fibrotic Premetastatic Niche
-
From gatekeepers to providers: regulation of immune functions by cancer-associated fibroblasts
-
αβ+/CD19+-depleted haploidentical stem cell transplantation for children with acute leukemia: Is there a protective effect of increased γδ+ T-cell content in the graft?
-
Association between diabetes mellitus and reduced efficacy of pembrolizumab in nonsmall cell lung cancer
-
Capturing the diversity of protein modifications on presented tumor antigens
-
p53 deficient breast cancer cells reprogram preadipocytes toward tumor-protective immunomodulatory cells
-
Final Results of a Phase i Trial of WST-11 (TOOKAD Soluble) Vascular-targeted Photodynamic Therapy for Upper Tract Urothelial Carcinoma
-
Post-translational modifications reshape the antigenic landscape of the MHC I immunopeptidome in tumors
-
The proteasome regulator PSME4 drives immune evasion and abrogates anti-tumor immunity in NSCLC
-
Modulating the proliferative and cytotoxic properties of patient-derived TIL by a synthetic immune niche of immobilized CCL21 and ICAM1
-
BBB opening by low pulsed electric fields, depicted by delayed-contrast MRI, enables efficient delivery of therapeutic doxorubicin doses into mice brains
-
Impact of TP53 Genomic Alterations in Large B-Cell Lymphoma Treated With CD19-Chimeric Antigen Receptor T-Cell Therapy
-
Cancer and cell cycle
-
Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression
-
Ets21C sustains a pro-regenerative transcriptional program in blastema cells of Drosophila imaginal discs
-
T Cells Promote Metastasis by Regulating Extracellular Matrix Remodeling following Chemotherapy
-
Bispecific antibodies increase the therapeutic window of CD40 agonists through selective dendritic cell targeting
-
Next Generation CD40 Agonistic Antibodies for Cancer Immunotherapy
-
ICAM-1 on Breast Cancer Cells Suppresses Lung Metastasis but Is Dispensable for Tumor Growth and Killing by Cytotoxic T Cells
-
AKTs do not translocate to the nucleus upon stimulation but AKT3 can constitutively signal from the nuclear envelope
-
Anti-CTLA-4 antibodies drive myeloid activation and reprogram the tumor microenvironment through FcγR engagement and type I interferon signaling
-
Cancer microbiome
-
Tumor-reactive antibodies evolve from non-binding and autoreactive precursors
-
A seven-transmembrane protein-TM7SF3, resides in nuclear speckles and regulates alternative splicing
-
A new function for the serine protease HtrA2 in controlling radiation-induced senescence in cancer cells
-
Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis
-
DestVI identifies continuums of cell types in spatial transcriptomics data
-
Targeted Drug Delivery for the Treatment of Blood Cancers
-
Beyond rare disorders: A new era for peroxisomal pathophysiology
-
Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors
-
Breast cancer plasticity is restricted by a LATS1-NCOR1 repressive axis
-
Conjugated Detergent Micelles as a Platform for IgM Purification
-
Pseudo-mutant P53 is a unique phenotype of DNMT3Amutated pre-leukemia
-
BREAst Cancer Personalised NuTrition (BREACPNT): dietary intervention in breast cancer survivors treated with endocrine therapy a protocol for a randomised clinical trial
-
Aptamer-Modified Au Nanoparticles: Functional Nanozyme Bioreactors for Cascaded Catalysis and Catalysts for Chemodynamic Treatment of Cancer Cells
-
Mechanisms of immune activation and regulation: lessons from melanoma
-
A necessary role for increased biglycan expression during L1mediated colon cancer progression
-
Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions
-
Galectin-8, cytokines, and the storm
-
Author Correction: Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability (Genome Biology, (2018), 19, 1, (37), 10.1186/s13059-018-1401-9)
-
ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells
-
The industrial genomic revolution: A new era in neuroimmunology
-
Stabilization of hESCs in two distinct substates along the continuum of pluripotency
-
NRas activity is regulated by dynamic interactions with nanoscale signaling clusters at the plasma membrane
-
Comparing Intraperitoneal and Intravenous Personalized ErbB2CAR-T for the Treatment of Epithelial Ovarian Cancer
-
Pediatric glioblastoma cells are sensitive to drugs that inhibit eIF2α dephosphorylation and its phosphomimetic S51D variant
-
Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression
-
Small molecule inhibitor of Igf2bp1 represses Kras and a pro-oncogenic phenotype in cancer cells
-
De novo-designed transmembrane domains tune engineered receptor functions
-
Space in cancer biology: its role and implications
-
Downregulation of the Tumor Suppressor TFF1 Is Required during Induction of Colon Cancer Progression by L1
-
Di-genic inheritance of germline POLE and PMS2 pathogenic variants causes a unique condition associated with pediatric cancer predisposition
-
A novel role for nucleolin in splice site selection
-
Smoking-induced microbial dysbiosis in health and disease
-
IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells
-
Dependence of ABCB1 transporter expression and function on distinct sphingolipids generated by ceramide synthases-2 and -6 in chemoresistant renal cancer
-
Ex vivo organotypic cultures for synergistic therapy prioritization identify patient-specific responses to combined MEK and Src inhibition in colorectal cancer
-
Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution
-
Polyclonal antibody-induced downregulation of HER1/EGFR and HER2 surpasses the effect of combinations of specific registered antibodies
-
H3-K27M-mutant nucleosomes interact with MLL1 to shape the glioma epigenetic landscape
-
The intricate nature of senescence in development and cell plasticity
-
Compartmentalization of the host microbiome: how tumor microbiota shapes checkpoint immunotherapy outcome and offers therapeutic prospects
-
Stochastic transitions as a major source of cancer heterogeneity
-
Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions
-
A coalition to healthe impact of the cardiac microenvironment
-
Cancer-associated fibroblasts in the single-cell era
-
CD74 as a regulator of transcription in normal B cells
-
An exercise-induced metabolic shield in distant organs blocks cancer progression and metastatic dissemination
-
Fatty acid transport protein 2 interacts with ceramide synthase 2 to promote ceramide synthesis
-
It's all in the combination: decoding the epigenome for cancer research and diagnostics
-
Human primed and naïve PSCs are both able to differentiate into trophoblast stem cells
-
Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas
-
Identification of the central intermediate in the extra-embryonic to embryonic endoderm transition through single-cell transcriptomics
-
Cardiovascular Disease Among Patients With AML and CHIP-Related Mutations
-
Immunogenicity and safety of BNT162b2 mRNA vaccine booster in actively treated patients with cancer
-
Aptamer-Functionalized Ce4+-Ion-Modified C-Dots: Peroxidase Mimicking Aptananozymes for the Oxidation of Dopamine and Cytotoxic Effects toward Cancer Cells
-
Spatiotemporal Omics-Refining the landscape of precision medicine
-
On the development of a neoantigen vaccine for the prevention of Lynch Syndrome
-
The brain-immune ecosystem: Implications for immunotherapy in defeating neurodegenerative diseases
-
5isomiR-183-5p|+2 elicits tumor suppressor activity in a negative feedback loop with E2F1
-
Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins
-
BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling
-
The interaction of CD4+ helper T cells with dendritic cells shapes the tumor microenvironment and immune checkpoint blockade response
-
Global DNA Methylation Analysis of Cancer-Associated Fibroblasts Reveals Extensive Epigenetic Rewiring Linked with RUNX1 Upregulation in Breast Cancer Stroma
-
Designing coordination polymers as multi-drug-self-delivery systems for tuberculosis and cancer therapy: in vitro viability and in vivo toxicity assessment
-
SmMIP-tools: a computational toolset for processing and analysis of single-molecule molecular inversion probes-derived data
-
Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism
-
Controls for Phylogeny and Robust Analysis in Pareto Task Inference
-
Actin filaments couple the protrusive tips to the nucleus through the I-BAR domain protein IRSp53 for migration of elongated cells on 1D fibers
-
An activation to memory differentiation trajectory of tumor-infiltrating lymphocytes informs metastatic melanoma outcomes
-
Anti-SARS-CoV-2 immunoadhesin remains effective against Omicron and other emerging variants of concern
-
Divergence of mutational signatures in association with breast cancer subtype
-
A Functional Pre-Screening Platform for Identifying Points of Vulnerability in the Cell Death Map of Human Melanoma Tumors
-
Interactive, integrated analysis of single-cell transcriptomic and phylogenetic data with PhyloVision
-
Bacterial infection disrupts established germinal center reactions through monocyte recruitment and impaired metabolic adaptation
-
Multi-NSAID-based Zn(
-
Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients
-
MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis
-
Visual barcodes for clonal-multiplexing of live microscopy-based assays
-
Whole-exome sequencing of HPV positive tonsillar and base of tongue squamous cell carcinomas reveals a global mutational pattern along with relapse-specific somatic variants
-
Early antitumor activity of oral Langerhans cells is compromised by a carcinogen
-
Nine receptors and binding proteins, four drugs, and one woman: Historical and personal perspectives
-
Genetic insight into BirtHoggDubé syndrome in Indian patients reveals novel mutations at FLCN
-
Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma
-
DOP53 In-depth characterisation of the serum antibody epitope repertoire in Inflammatory Bowel Disease by high-throughput phage-displayed immunoprecipitation sequencing
-
CXCR4 and CD74 together enhance cell survival in response to macrophage migration-inhibitory factor in chronic lymphocytic leukemia
-
AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer
-
Characteristics & outcomes of cancer patients with COVID-19: A multicentre retrospective study from India
-
Structure-guided design and characterization of a clickable, covalent PARP16 inhibitor
-
Blockade of the protease ADAM17 ameliorates experimental pancreatitis
-
Brain metastases: Not all tumors are created equal
-
Sex Biases in Cancer and Autoimmune Disease Incidence Are Strongly Positively Correlated with Mitochondrial Gene Expression across Human Tissues
-
Expert survey on management of prostate cancer in India: Real-world insights into practice patterns
-
A spatial perspective on bacteria in tumours
-
Spaceflight-Associated Changes of snoRNAs in Peripheral Blood Mononuclear Cells and Plasma ExosomesA Pilot Study
-
Mitochondrial ROS drive resistance to chemotherapy and immune-killing in hypoxic non-small cell lung cancer
-
Polysome-CAGE of TCL1-driven chronic lymphocytic leukemia revealed multiple N-terminally altered epigenetic regulators and a translation stress signature
-
A similarity-based method for predicting enzymatic functions in yeast uncovers a new AMP hydrolase
-
S6K1 phosphorylates Cdk1 and MSH6 to regulate DNA repair
-
Spatial organization and early signaling of the B-cell receptor in CLL
-
Mouse Modeling Dissecting MacrophageBreast Cancer Communication Uncovered Roles of PYK2 in Macrophage Recruitment and Breast Tumorigenesis
-
Intratumor heterogeneity and anti-tumor immunity shape one another bidirectionally
-
Germline genetic biomarkers to stratify patients for personalized radiation treatment
-
The microbiome and human cancer
-
Single Instillation of Hypertonic Saline Immediately Following Transurethral Resection of Bladder Tumor for Recurrence Prevention A Phase I Study
-
The myeloid sarcoma treated by Venetoclax with hypomethylating agent followed by stem cell transplantation: rare case report
-
Albumin-EDTA-Vanadium Is a Powerful Anti-Proliferative Agent, Following Entrance into Glioma Cells via Caveolae-Mediated Endocytosis
-
Identification of variable stages in murine pancreatic tumors by a multiparametric approach employing hyperpolarized 13C MRSI, 1H diffusivity and 1H T1 MRI
-
Improving deuterium metabolic imaging (DMI) signaltonoise ratio by spectroscopic multiecho bSSFP: A pancreatic cancer investigation
-
TP53 missense mutations in PDAC are associated with enhanced fibrosis and an immunosuppressive microenvironment
-
Conformational switches and redox properties of the colon cancerassociated human lectin ZG16
-
Constitutive low expression of antiviral effectors sensitizes melanoma cells to a novel oncolytic virus
-
Vascular-Targeted Photodynamic Therapy for Prostate Cancer
-
Structured elements drive extensive circular RNA translation
-
Decoding cancer biology one cell at a time
-
Learned Super Resolution Ultrasound for Improved Breast Lesion Characterization
-
Melanoma models for the next generation of therapies
-
Spatially organized multicellular immune hubs in human colorectal cancer
-
Breast cancer is marked by specific, Public T-cell receptor CDR3 regions shared by mice and humans
-
Identification of bacteria-derived HLA-bound peptides in melanoma
-
CD84 is a regulator of the immunosuppressive microenvironment in multiple myeloma
-
Chromothripsis drives the evolution of gene amplification in cancer
-
Persistent Inflammatory Stimulation Drives the Conversion of MSCs to Inflammatory CAFs That Promote Pro-Metastatic Characteristics in Breast Cancer Cells
-
Proteomic profiling of tissue exosomes indicates continuous release of malignant exosomes in urinary bladder cancer patients, even with pathologically undetectable tumour
-
P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression
-
Isolation of a gene cluster from Armillaria gallica for the synthesis of armillyl orsellinatetype sesquiterpenoids
-
Relevance of Membrane Contact Sites in Cancer Progression
-
The glycine arginine-rich domain of the RNA-binding protein nucleolin regulates its subcellular localization
-
The extracellular matrix protein agrin is essential for epicardial epithelial-to-mesenchymal transition during heart development
-
CYP46A1-APOE axis at the choroid plexus is compromised in Alzheimer's disease but is amenable to rescue
-
The consumption of cholesterol-enriched diets conditions the development of a subtype of hcc with high aggressiveness and poor prognosis
-
Molecular principles of recruitment and dynamics of guest proteins in liquid droplets
-
Autophagy in major human diseases
-
The Key Role of Patient Involvement in the Development of Core Outcome Sets in Prostate Cancer
-
Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation
-
Alternative splicing of the inhibitory immune checkpoint receptor SLAMF6 generates a dominant positive form, boosting T-cell effector functions
-
Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles
-
Tumour irradiation combined with vascular-targeted photodynamic therapy enhances antitumour effects in pre-clinical prostate cancer
-
BCL-XL blockage in TNBC models confers vulnerability to inhibition of specific cell cycle regulators
-
The context-specific roles of urea cycle enzymes in tumorigenesis
-
Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma
-
Diffusion is directional: Innovative diffusion tensor imaging to improve prostate cancer detection
-
Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies
-
The relationship between the plasma proinflammatory cytokine levels of depressed/anxious children and their parents
-
The prospects of tumor chemosensitivity testing at the single-cell level
-
GDF11 restricts aberrant lipogenesis and changes in mitochondrial structure and function in human hepatocellular carcinoma cells
-
Multiplexed imaging analysis of the tumor-immune microenvironment reveals predictors of outcome in triple-negative breast cancer
-
TENT4A Non-Canonical Poly(A) Polymerase Regulates DNA-Damage Tolerance via Multiple Pathways That Are Mutated in Endometrial Cancer
-
Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models
-
Anti-tumour immunity induces aberrant peptide presentation in melanoma
-
Efficient acquisition of tens of thousands of short tandem repeats in single-cell whole-genome-amplified DNA
-
Coordinated regulation of WNT/β-catenin, c-Met, and integrin signalling pathways by miR-193b controls triple negative breast cancer metastatic traits
-
Clump sequencing exposes the spatial expression programs of intestinal secretory cells
-
β2 Integrin Signaling Cascade in Neutrophils: More Than a Single Function
-
Proteomic patterns associated with response to breast cancer neoadjuvant treatment
-
Reduced lamin a/c does not facilitate cancer cell transendothelial migration but compromises lung metastasis
-
CircRNAs: role in human diseases and potential use as biomarkers
-
Targeting nucleotide metabolism as the nexus of viral infections, cancer, and the immune response
-
Immunotherapy for Triple-Negative Breast Cancer
-
Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis
-
Principles of signaling pathway modulation for enhancing human naive pluripotency induction
-
Evolution of fibroblasts in the lung metastatic microenvironment is driven by stage-specific transcriptional plasticity
-
Circadian Misalignment and Metabolic Disorders: A Story of Twisted Clocks
-
The key roles of cancer stem cell-derived extracellular vesicles
-
TNF-α Regulated Endometrial Stroma Secretome Promotes Trophoblast Invasion
-
Egfr in cancer: Signaling mechanisms, drugs and acquired resistance
-
Conformation-specific inhibitory anti-mmp-7 monoclonal antibody sensitizes pancreatic ductal adenocarcinoma cells to chemotherapeutic cell kill
-
Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo
-
Clinical Proteomics of Metastatic Melanoma Reveals Profiles of Organ Specificity and Treatment Resistance
-
Male predominance in AML is associated with specific preleukemic mutations
-
Biological and therapeutic implications of a unique subtype of NPM1 mutated AML
-
A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion
-
Interacting evolutionary pressures drive mutation dynamics and health outcomes in aging blood
-
Roles for growth factors and mutations in metastatic dissemination
-
A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma
-
Single cell biologya Keystone Symposia report
-
Using a recently approved tumor mutational burden biomarker to stratify patients for immunotherapy may introduce a sex bias
-
Metabolic decisions in development and diseasea Keystone Symposia report
-
The evolution of leukaemia from preleukaemic and leukaemic stem cells
-
Tumour inflammation signature and expression of S100A12 and HLA class I improve survival in HPV-negative hypopharyngeal cancer
-
Reciprocal REGγ-mTORC1 regulation promotes glycolytic metabolism in hepatocellular carcinoma
-
Avidity optimization of a MAGE-A1-specific TCR with somatic hypermutation
-
MT1 and MT2 melatonin receptors play opposite roles in brain cancer progression
-
Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis
-
NASH limits anti-tumour surveillance in immunotherapy-treated HCC
-
Leptin modulates gene expression in the heart, cardiomyocytes and the adipose tissue thus mitigating LPS-induced damage
-
Combined presentation and immunogenicity analysis reveals a recurrent RAS.Q61K neoantigen in melanoma
-
Cancer-associated fibroblasts promote aggressive gastric cancer phenotypes via heat shock factor 1-mediated secretion of extracellular vesicles
-
ACK1 is dispensable for development, skin tumor formation, and breast cancer cell proliferation
-
Proteolysis Targeting Chimeras for BTK Efficiently Inhibit B-Cell Receptor Signaling and Can Overcome Ibrutinib Resistance in CLL Cells
-
Positron Emission Tomography/Computed Tomography with Gallium-68labeled Prostate-specific Membrane Antigen Detects Relapse After Vascular-targeted Photodynamic Therapy in a Prostate Cancer Model
-
R_Enhancement of Biological Activities of Copper(II) Complexes Containing Guanidine Derivatives by Enrofloxacin
-
Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes
-
The evolutionarily conserved long non-coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms
-
Single-cell transcriptomic analyses provide insights into the developmental origins of neuroblastoma
-
Astrocytes Downregulate Inflammation in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome: Applicability to COVID-19
-
Neuronal regulated ire-1-dependent mRNA decay controls germline differentiation in Caenorhabditis elegans
-
Identification of resistance pathways and therapeutic targets in relapsed multiple myeloma patients through single-cell sequencing
-
Natural and cryptic peptides dominate the immunopeptidome of atypical teratoid rhabdoid tumors
-
SMURF2-mediated ubiquitin signaling plays an essential role in the regulation of PARP1 PARylating activity, molecular interactions, and functions in mammalian cells
-
XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis
-
Albumin-Methotrexate Prodrug Analogues That Undergo Intracellular Reactivation Following Entrance into Cancerous Glioma Cells
-
Combined ox40 agonist and pd-1 inhibitor immunotherapy improves the efficacy of vascular targeted photodynamic therapy in a urothelial tumor model
-
Decoupling epithelial-mesenchymal transitions from stromal profiles by integrative expression analysis
-
Treatment results from a phase I study of WST11 phototherapy (VTP) for upper tract urothelial carcinoma
-
The collagenmodifying enzyme plod2 is induced and required during l1mediated colon cancer progression
-
Senescent cells and the incidence of age-related diseases
-
Accelerating AXL targeting for TNBC therapy
-
The AXL-PYK2-PKCα axis as a nexus of stemness circuits in TNBC
-
Putative Blood Somatic Mutations in Post-Traumatic Stress Disorder-Symptomatic Soldiers: High Impact of Cytoskeletal and Inflammatory Proteins
-
Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy
-
IRS1 phosphorylation underlies the non-stochastic probability of cancer cells to persist during EGFR inhibition therapy
-
Host-Dependent Phenotypic Resistance to EGFR Tyrosine Kinase Inhibitors
-
Neoadjuvant vascular-targeted photodynamic therapy improves survival and reduces recurrence and progression in a mouse model of urothelial cancer
-
Transient genomic instability drives tumorigenesis through accelerated clonal evolution
-
Recurrent deletions in clonal hematopoiesis are driven by microhomology-mediated end joining
-
Skin exposure to UVB light induces a skin-brain-gonad axis and sexual behavior
-
Artificial Intelligence and Early Detection of Pancreatic Cancer: 2020 Summative Review
-
Meningeal lymphoid structures are activated under acute and chronic spinal cord pathologies
-
Therapeutic efficacy of 225Ac-PSMA-617 targeted alpha therapy in patients of metastatic castrate resistant prostate cancer after taxane-based chemotherapy
-
Aberrant transcriptional and post-transcriptional regulation of SPAG5, a YAP-TAZ-TEAD downstream effector, fuels breast cancer cell proliferation
-
VEGFC/FLT4-induced cell-cycle arrest mediates sprouting and differentiation of venous and lymphatic endothelial cells
-
Proteogenomics of glioblastoma associates molecular patterns with survival
-
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation
-
Immunoediting role for major vault protein in apoptotic signaling induced by bacterial N-acyl homoserine lactones
-
SelfComplementary Zwitterionic Peptides Direct Nanoparticle Assembly and Enable Enzymatic Selection of Endocytic Pathways
-
Engineered variants of the Ras effector protein RASSF5 (NORE1A) promote anti-cancer activities in lung adenocarcinoma
-
Microbiome and cancer
-
Tumor heterogeneity
-
Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ)
-
MEK inhibition reverses aberrant signaling in melanoma cells through reorganization of nras and braf in self nanoclusters
-
Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts
-
Microtubule destabilization is a critical checkpoint of chemotaxis and transendothelial migration in melanoma cells but not in T cells
-
Beyond cells: The extracellular circulating 20S proteasomes
-
P32-specific CAR T cells with dual antitumor and antiangiogenic therapeutic potential in gliomas
-
Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis
-
SCIRT lncRNA Restrains Tumorigenesis by Opposing Transcriptional Programs of Tumor-Initiating Cells
-
Tumor cells in light-chain amyloidosis and myeloma show distinct transcriptional rewiring of normal plasma cell development
-
Hemopressin as a breakthrough for the cannabinoid field
-
β2-Integrin Adhesion Regulates Dendritic Cell Epigenetic and Transcriptional Landscapes to Restrict Dendritic Cell Maturation and Tumor Rejection
-
PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
-
TSHZ2 is an EGF-regulated tumor suppressor that binds to the cytokinesis regulator PRC1 and inhibits metastasis
-
Mechanism of cholangiocellular damage and repair during cholestasis
-
Intratumoral heterogeneity in cancer progression and response to immunotherapy
-
Retrospective cell lineage reconstruction in humans by using short tandem repeats
-
Targeting autocrine amphiregulin robustly and reproducibly inhibits ovarian cancer in a syngeneic model: roles for wildtype p53
-
Cell Senescence, DNA Damage, and Metabolism
-
Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response
-
Systematic detection of m6A-modified transcripts at single-molecule and single-cell resolution
-
Deuterium MRSI characterizations of glucose metabolism in orthotopic pancreatic cancer mouse models
-
Gatekeepers of the gut: The roles of proteasomes at the gastrointestinal barrier
-
alpha-Actinin-4 drives invasiveness by regulating myosin IIB expression and myosin IIA localization
-
Proteomic analysis of necroptotic extracellular vesicles
-
Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression
-
Bimodal magnetic resonance and optical imaging of extracellular matrix remodelling by orthotopic ovarian tumours
-
Effect of ibrutinib on the ifn response of chronic lymphocytic leukemia cells
-
Stromal Expression of the Core Clock Gene Period 2 Is Essential for Tumor Initiation and Metastatic Colonization
-
Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation
-
The microbiome and cytosolic innate immune receptors
-
Myotubularin-related protein 7 activates peroxisome proliferator-activated receptor-gamma
-
The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway
-
Regulation of eIF2α by RNF4 Promotes Melanoma Tumorigenesis and Therapy Resistance
-
Modeling Multiplexed Images with Spatial-LDA Reveals Novel Tissue Microenvironments
-
Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma
-
Are noncommunicable diseases communicable?
-
Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity
-
Genomic retargeting of p53 and CTCF is associated with transcriptional changes during oncogenic HRas-induced transformation
-
A single cell atlas of the human liver tumor microenvironment
-
Induction and characterization of pancreatic cancer in a transgenic pig model
-
Direct stimulation of ERBB2 highlights a novel cytostatic signaling pathway driven by the receptor-Thr(701) phosphorylation
-
Mutant p53 oncogenicity: dominant-negative or gain-of-function?
-
Developments in Vascular-Targeted Photodynamic Therapy for Urologic Malignancies
-
The pro-oncogenic effect of the lncRNA H19 in the development of chronic inflammation-mediated hepatocellular carcinoma
-
Predicting and affecting response to cancer therapy based on pathway-level biomarkers
-
Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth
-
Targeting HER3, a Catalytically Defective Receptor Tyrosine Kinase, Prevents Resistance of Lung Cancer to a Third-Generation EGFR Kinase Inhibitor
-
A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma
-
Interleukin 10 Restores Lipopolysaccharide-Induced Alterations in Synaptic Plasticity Probed by Repetitive Magnetic Stimulation
-
Reduction in MLKL-mediated endosomal trafficking enhances the TRAIL-DR4/5 signal to increase cancer cell death
-
Mitochondrial carrier homolog 2 is necessary for AML survival
-
A framework for advancing our understanding of cancer-associated fibroblasts
-
A single-cell landscape of high-grade serous ovarian cancer
-
Interleukin-9 regulates macrophage activation in the progressive multiple sclerosis brain
-
Rational design of universal immunotherapy for TfR1-tropic arenaviruses
-
Immune related proteins and tumor infiltrating CD8+lymphocytes in hypopharyngeal cancer in relation to human papillomavirus (HPV) and clinical outcome
-
Pleiotropic tumor suppressor functions of WWOX antagonize metastasis
-
NF-κB-miR-155 axis activation mediates ovulation-induced oncogenic effects in fallopian tube epithelium
-
Modeling biological and genetic diversity in upper tract urothelial carcinoma with patient derived xenografts
-
Optimal multiparametric set-up modelled for best survival outcomes in palliative treatment of liver malignancies: unsupervised machine learning and 3 PM recommendations
-
Single-cell analysis of clonal maintenance of transcriptional and epigenetic states in cancer cells
-
Immunomodulatory Properties of Leishmania Extracellular Vesicles During Host-Parasite Interaction: Differential Activation of TLRs and NF-kappa B Translocation by Dermotropic and Viscerotropic Species
-
The Glioma Stem Cell Model in the Era of Single-Cell Genomics
-
Inter-Tumor Heterogeneity-Melanomas Respond Differently to GM-CSF-Mediated Activation
-
Microbiome genomics for cancer prediction
-
Breast Cancer-Derived Microparticles Reduce Cancer Cell Adhesion, an Effect Augmented by Chemotherapy
-
Time-resolved profiling reveals ATF3 as a novel mediator of endocrine resistance in breast cancer
-
CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy
-
Pharmacological LRH-1/Nr5a2 inhibition limits pro-inflammatory cytokine production in macrophages and associated experimental hepatitis
-
Effect of IV Administration of a Gadolinium-Based Contrast Agent on Breast Diffusion-Tensor Imaging
-
Nanobodies Targeting Prostate-specific Membrane Antigen for the Imaging and Therapy of Prostate Cancer
-
Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models
-
Emerging roles of ECM remodeling processes in cancer
-
Cardiac remodeling secondary to chronic volume overload is attenuated by a novel MMP9/2 blocking antibody
-
Immunological Features of Non-neuronal Brain Cells: Implications for Alzheimer's Disease Immunotherapy
-
A Unified Linear Viscoelastic Model of the Cell Nucleus Defines the Mechanical Contributions of Lamins and Chromatin
-
The human tumor microbiome is composed of tumor type-specific intracellular bacteria
-
Cu(II)-Metallacryptands Self-Assembled to Vesicular Aggregates Capable of Encapsulating and Transporting an Anticancer Drug Inside Cancer Cells
-
The biomarkers of hyperprogressive disease in PD-1/PD-L1 blockage therapy
-
Interleukin-10 Prevents Pathological Microglia Hyperactivation following Peripheral Endotoxin Challenge
-
IL-16 processing in sentinel node regulatory T cells is a factor in bladder cancer immunity
-
Rational Design and Synthesis of Methyl-β-d-galactomalonyl Phenyl Esters as Potent Galectin-8N Antagonists
-
Diffusion-weighted breast MRI of malignancies with submillimeter resolution and immunity to artifacts by spatiotemporal encoding at 3T
-
Malignant cell-specific CXCL14 promotes tumor lymphocyte infiltration in oral cavity squamous cell carcinoma
-
Role of m(6)A in Embryonic Stem Cell Differentiation and in Gametogenesis
-
Increased circulatory IL-6 during 8-week fluoxetine treatment is a risk factor for suicidal behaviors in youth
-
Wnt/β-catenin target genes in colon cancer metastasis: The special case of l1cam
-
The ECM path of senescence in aging: components and modifiers
-
The mitochondrial carrier Citrin plays a role in regulating cellular energy during carcinogenesis
-
Paying the price for standing tall: Fluid mechanics of prostate pathology
-
Diffusivity in breast malignancies analyzed for b>1000s/mm 2 at 1mm inplane resolutions: Insight from Gaussian and nonGaussian behaviors
-
LifeTime and improving European healthcare through cell-based interceptive medicine
-
Single-cell genomic approaches for developing the next generation of immunotherapies
-
Lipid Transfer Proteins and Membrane Contact Sites in Human Cancer
-
Mice defective in interferon signaling help distinguish between primary and secondary pathological pathways in a mouse model of neuronal forms of Gaucher disease
-
Dasatinib response in acute myeloid leukemia is correlated with FLT3/ITD, PTPN11 mutations and a unique gene expression signature
-
Bystander IFN-gamma activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment
-
Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia
-
A 20-Year Journey from Axonal Injury to Neurodegenerative Diseases and the Prospect of Immunotherapy for Combating Alzheimer's Disease
-
Intravital imaging of vascular anomalies and extracellular matrix remodeling in orthotopic pancreatic tumors
-
High-resolution optoacoustic imaging of tissue responses to vascular-targeted therapies
-
A Division of Labor between YAP and TAZ in Non-Small Cell Lung Cancer
-
An increase in IL-6 levels at 6-month follow-up visit is associated with SSRI-emergent suicidality in high-risk children and adolescents treated with fluoxetine
-
High-Throughput Screen Identifies Host and Microbiota Regulators of Intestinal Barrier Function
-
Identification of a potent and selective covalent Pin1 inhibitor
-
Directed evolution of therapeutic antibodies targeting glycosylation in cancer
-
DNA Repair Biomarker for Lung Cancer Risk and its Correlation With Airway Cells Gene Expression
-
The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic
-
Introducing PIONEER: a project to harness big data in prostate cancer research
-
Generation of human endothelium in pig embryos deficient in ETV2
-
The potential anti-inflammatory and anti-nociceptive effects of rat hemopressin (PVNFKFLSH) in experimental arthritis
-
Nasopharyngeal carcinoma joins the single-cell party
-
Trypanosoma cruzi-Infected Human Macrophages Shed Proinflammatory Extracellular Vesicles That Enhance Host-Cell Invasion via Toll-Like Receptor 2
-
Characterization of the human tumor microbiome reveals tumor-type specific intra-cellular bacteria
-
beta-Catenin safeguards the ground state of mouse pluripotency by strengthening the robustness of the transcriptional apparatus
-
Transcriptional profiling reveals a subset of human breast tumors that retain wt TP53 but display mutant p53-associated features
-
Modeling Heterogeneity of Triple-Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance
-
Mapping cell phenotypes in breast cancer
-
Dual-Targeted Autoimmune Sword in Fatal Epilepsy: Patient's glutamate receptor AMPA GluR3B peptide autoimmune antibodies bind, induce Reactive Oxygen Species (ROS) in, and kill both human neural cells and T cells
-
Proteasome-dependent degradation of Smad7 is critical for lung cancer metastasis
-
Across the Globe: Proteogenomic Landscapes of Lung Cancer
-
Publisher Correction: Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome (BMC Biology, (2020), 18, 1, (163), 10.1186/s12915-020-00893-2)
-
Metabolic alterations in the tumor microenvironment and their role in oncogenesis
-
Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma
-
Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer
-
Targeting Metabolic Plasticity and flexibility Dynamics for Cancer Therapy
-
Treatment of Multiple Myeloma Using Chimeric Antigen Receptor T Cells with Dual Specificity
-
NOP10 predicts lung cancer prognosis and its associated small nucleolar RNAs drive proliferation and migration
-
The Animal Lectin Galectin-8 Promotes Cytokine Expression and Metastatic Tumor Growth in Mice
-
Deconstructing tumor heterogeneity: The stromal perspective
-
Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome
-
Identification of a truncated beta 1-chimaerin variant that inactivates nuclear Rac1
-
The microbiota programs DNA methylation to control intestinal homeostasis and inflammation
-
HSF1 and Molecular Chaperones in Biology and Cancer
-
Roles for receptor tyrosine kinases in tumor progression and implications for cancer treatment
-
Dissecting cellular crosstalk by sequencing physically interacting cells
-
Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action
-
Novel Proteome Extraction Method Illustrates a Conserved Immunological Signature of MSI-H Colorectal Tumors.
-
Tumour heterogeneity and the evolutionary trade-offs of cancer
-
Efficient targeted degradation via reversible and irreversible covalent PROTACs
-
PRMT1 inhibition induces differentiation of colon cancer cells
-
Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma
-
Cellular Origins of the Lymphatic Endothelium: Implications for Cancer Lymphangiogenesis: Implications for Cancer Lymphangiogenesis
-
Fluorescent Silica Nanoparticles to Label Metastatic Tumor Cells in Mineralized Bone Microenvironments
-
Bone marrow dendritic cells support the survival of chronic lymphocytic leukemia cells in a CD84 dependent manner
-
Integration of intra-sample contextual error modeling for improved detection of somatic mutations from deep sequencing
-
Donor cell leukemia: reappearance of gene mutations in donor cells - more than an incidental phenomenon?
-
Proteomic analysis of circulating extracellular vesicles identifies potential markers of breast cancer progression, recurrence, and response
-
STING cyclic dinucleotide sensing originated in bacteria
-
Theileria parasites subvert E2F signaling to stimulate leukocyte proliferation
-
Hitting KRAS When Its Down
-
Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest
-
Targeted therapy and drug resistance in triple-negative breast cancer: the EGFR axis
-
Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression
-
The Role of HSF1 and the Chaperone Network in the Tumor Microenvironment
-
Inflammasome activation and regulation: toward a better understanding of complex mechanisms
-
PhISCS-BnB: a fast branch and bound algorithm for the perfect tumor phylogeny reconstruction problem
-
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
-
Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4(+) and PDPN+ CAFs to clinical outcome
-
Tackling the Many Facets of Glioblastoma Heterogeneity
-
Breast cancer associated with paraneoplastic cerebellar degeneration: A case series
-
Nuclear P38: Roles in Physiological and Pathological Processes and Regulation of Nuclear Translocation
-
Less is more: reducing the number of administered chimeric antigen receptor T cells in a mouse model using a mathematically guided approach
-
Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors
-
Synaptic Protein Degradation Controls Sexually Dimorphic Circuits through Regulation of DCC/UNC-40
-
Recent insights into the role of L1CAM in cancer initiation and progression
-
Nutrition Regulates Innate Immunity in Health and Disease
-
Urinary Exosomes from Bladder Cancer Patients Show a Residual Cancer Phenotype despite Complete Pathological Downstaging
-
BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression
-
Leptin modulates gene expression in the heart and cardiomyocytes towards mitigating ischemia-induced damage
-
Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer
-
MIBI-TOF: A multiplexed imaging platform relates cellular phenotypes and tissue structure
-
Cooperativity between stromal cytokines drives the invasive migration of human breast cancer cells
-
Author Correction: Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells (Scientific Reports, (2017), 7, 1, (16345), 10.1038/s41598-017-16558-0)
-
Prediction of PD-L1 inhibition effects for HIV-infected individuals
-
A universal anti-cancer vaccine: Chimeric invariant chain potentiates the inhibition of melanoma progression and the improvement of survival
-
Tumor diversity and the trade-off between universal cancer tasks
-
Imaging of Red-Shifted Light From Bioluminescent Tumors Using Fluorescence by Unbound Excitation From Luminescence
-
Adipocytes sensitize melanoma cells to environmental TGF-beta cues by repressing the expression of miR-211
-
Inhibition of a pancreatic cancer model by cooperative pairs of clinically approved and experimental antibodies
-
A niche-dependent myeloid transcriptome signature defines dormant myeloma cells
-
Cancer exome-based identification of tumor neo-antigens using mass spectrometry
-
Immunohistochemical quantification of partial-EMT in oral cavity squamous cell carcinoma primary tumors is associated with nodal metastasis
-
SLAMF9 regulates pDC homeostasis and function in health and disease
-
Long Noncoding RNA MALAT1 Regulates Cancer Glucose Metabolism by Enhancing mTOR-Mediated Translation of TCF7L2
-
Exome Sequencing of ABCB5 Identifies Recurrent Melanoma Mutations that Result in Increased Proliferative and Invasive Capacities
-
Forces and constraints controlling podosome assembly and disassembly
-
SLAMF receptors on normal and malignant B cells
-
The cancer microbiome
-
Single-Cell RNA Sequencing in Cancer: Lessons Learned and Emerging Challenges
-
AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer
-
GDF11 Implications in Cancer Biology and Metabolism. Facts and Controversies
-
Deciphering Human Tumor Biology by Single-Cell Expression Profiling
-
Molecular Logic as a Means to Assess Therapeutic Antidotes
-
PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model
-
PAR1 Expression Predicts Clinical G-CSF CD34+ HSPC Mobilization and Repopulation Potential in Transplanted Patients
-
The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids
-
Arginine refolds, stabilizes, and restores function of mutant pVHL proteins in animal model of the VHL cancer syndrome
-
KLF4 sensitizes the colon cancer cell HCT-15 to cisplatin by altering the expression of HMGB1 and hTERT
-
Leukocyte-specific siRNA delivery revealing IRF8 as a potential anti-inflammatory target
-
Size-tunable MRI-visible nitroxide-based magnetic mixed micelles: Preparation, stability, and theranostic application
-
Kinetic modeling of DUSP regulation in herceptin-resistant HER2-positive breast cancer
-
In vivo effects of temperature on the heart and pyloric rhythms in the crab Cancer borealis
-
Genome analysis and knowledge-driven variant interpretation with TGex
-
The Nuclear Translocation of Mitogen-Activated Protein Kinases: Molecular Mechanisms and Use as Novel Therapeutic Target
-
Meprin β induces activities of A disintegrin and metalloproteinases 9, 10, and 17 by specific prodomain cleavage
-
RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction
-
Liver and Steroid Hormones - Can a Touch of p53 Make a Difference?
-
Genome-wide miRNA methylome analysis in oral cancer: possible biomarkers associated with patient survival
-
Personalized Nutrition: Are We There Yet?
-
Transient p53-Mediated Regenerative Senescence in the Injured Heart
-
Correction: RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells (vol 8, 653, 2018): RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells (Scientific Reports, (2018), 8, 1, (653), 10.1038/s41598-017-18851-4)
-
Hepatitis C virus core protein interacts with cellular metastasis suppressor Nm23-H1 and promotes cell migration and invasion
-
Corrigendum to 'p53 balances between tissue hierarchy and anarchy'
-
Modelling the role of dual specificity phosphatases in herceptin resistant breast cancer cell lines
-
Increased expression of cathepsin D is required for L1-mediated colon cancer progression
-
The role of the microbiome in NAFLD and NASH
-
N-Acetyl-L-Cysteine Supplement in Early Life or Adulthood Reduces Progression of Diabetes in Nonobese Diabetic Mice
-
Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma
-
Resistance to paclitaxel is associated with a variant of the gene BCL2 in multiple tumor types
-
Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion
-
Molecular pathways of senescence regulate placental structure and function
-
Simultaneous Integration of Multi-omics Data Improves the Identification of Cancer Driver Modules
-
Reduced CTL motility and activity in avascular tumor areas
-
The transcriptional profile of circulating myeloid derived suppressor cells correlates with tumor development and progression in mouse
-
Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis
-
IKK epsilon regulates the breast cancer stem cell phenotype
-
c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression
-
Epigenetics and the microbiome
-
Pro-inflammatory Cytokines Alter the Immunopeptidome Landscape by Modulation of HLA-B Expression
-
The landscape of tiered regulation of breast cancer cell metabolism
-
The Dietary Flavonoid, Luteolin, Negatively Affects Neuronal Differentiation
-
The ADAM17 Protease Promotes Tobacco Smoke Carcinogen-induced Lung Tumourigenesis
-
The therapeutic potential of tuftsin-phosphorylcholine in giant cell arteritis
-
A Mitochondrial VDAC1-Based Peptide Greatly Suppresses Steatosis and NASH-Associated Pathologies in a Mouse Model
-
Proteomic and genomic signatures of repeat instability in cancer and adjacent normal tissues
-
Proteomic analysis reveals greater abundance of complement and inflammatory proteins in subcutaneous adipose tissue from postpartum cows treated with sodium salicylate
-
A cancer associated somatic mutation in LC3B attenuates its binding to E1-like ATG7 protein and subsequent lipidation
-
KLF4 expression in the surgical cut margin is associated with disease relapse of oral squamous cell carcinoma
-
Accelerated Hypofractionated Radiation Therapy for Elderly Frail Bladder Cancer Patients Unfit for Surgery or Chemotherapy
-
Cross-Talk between Receptor Tyrosine Kinases AXL and ERBB3 Regulates Invadopodia Formation in Melanoma Cells
-
Daily light and darkness onset and circadian rhythms metabolically synchronize hematopoietic stem cell differentiation and maintenance: The role of bone marrow norepinephrine, tumor necrosis factor, and melatonin cycles
-
Expanding the Organismal Proteostasis Network: Linking Systemic Stress Signaling with the Innate Immune Response
-
The circRNA-microRNA code: emerging implications for cancer diagnosis and treatment
-
Optimizing T-cell receptor avidity with somatic hypermutation
-
BCR affinity differentially regulates colonization of the subepithelial dome and infiltration into germinal centers within Peyer's patches
-
High efficiency error suppression for accurate detection of low-frequency variants
-
Cancer immunotherapy: The dawn of antibody cocktails
-
Increased Expression of MicroRNA 551a by c-Fos Reduces Focal Adhesion Kinase Levels and Blocks Tumorigenesis
-
Melanoma-derived extracellular vesicles instigate proinflammatory signaling in the metastatic microenvironment
-
A new pyrrole based small molecule from Tinospora cordifolia induces apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity
-
Nonmuscle myosin IIA and IIB differentially modulate migration and alter gene expression in primary mouse tumorigenic cells
-
Immunization with mannosylated nanovaccines and inhibition of the immune-suppressing microenvironment sensitizes melanoma to immune checkpoint modulators
-
CRISPR/Cas9-based Knockout Strategy Elucidates Components Essential for Type 1 Interferon Signaling in Human HeLa Cells
-
p53: not just a tumor suppressor
-
Gain-of-Function Mutant p53: All the Roads Lead to Tumorigenesis
-
ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer
-
RASA2 and NF1; two-negative regulators of Ras with complementary functions in melanoma
-
UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors
-
Role of phospholipase D in migration and invasion induced by linoleic acid in breast cancer cells
-
Ser289 phosphorylation activates both DAPK1 and DAPK2 but in response to different intracellular signaling pathways
-
Cytokine sensitivity screening highlights BMP4 pathway signaling as a therapeutic opportunity in ER+ breast cancer
-
Catalytic degradation of fluorouracil and its derivatives by copper-based nanoparticles
-
An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma
-
The Immune System Computes the State of the Body: Crowd Wisdom, Machine Learning, and Immune Cell Reference Repertoires Help Manage Inflammation
-
ISG15 induction is required during L1-mediated colon cancer progression and metastasis
-
Single-cell sequencing and its applications in head and neck cancer
-
Microvesicle proteomic profiling of uterine liquid biopsy for ovarian cancer early detection
-
Radiation-induced DNA damage response and resistance in colorectal cancer stem-like cells
-
Evolutionary trajectory of leukemic clones and its clinical implications
-
Nuclear ERK: Mechanism of Translocation, Substrates, and Role in Cancer
-
Connections Between Clonal Hematopoiesis, Cardiovascular Disease, and Cancer A Review
-
Effectiveness of the combination of vascular targeted photodynamic therapy and anti-cytotoxic T-lymphocyte-associated antigen 4 in a preclinical mouse model of urothelial carcinoma
-
New insights into YAP/TAZ nucleo-cytoplasmic shuttling: new cancer therapeutic opportunities?
-
Bacillus Calmette-Guerin (BCG) therapy lowers the incidence of Alzheimer's disease in bladder cancer patients
-
UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma
-
PIK3CA in cancer: The past 30 years
-
Scaling laws indicate distinct nucleation mechanisms of holes in the nuclear lamina
-
Transmissible inflammation-induced colorectal cancer in inflammasome-deficient mice
-
Exosomes as a storehouse of tissue remodeling proteases and mediators of cancer progression
-
Modulation of MS-like disease by a multi epitope protein is mediated by induction of CD11c(+) CD1lb(+) Grl(+) myeloid-derived dendritic cells
-
MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy
-
Cancer-Associated Eukaryotic Translation Initiation Factor 1A Mutants Impair Rps3 and Rps10 Binding and Enhance Scanning of Cell Cycle Genes
-
STAT3 Post-Translational Modifications Drive Cellular Signaling Pathways in Prostate Cancer Cells
-
Ceramide domains in health and disease: A biophysical perspective
-
MicroRNAs Affect Complement Regulator Expression and Mitochondrial Activity to Modulate Cell Resistance to Complement-Dependent Cytotoxicity
-
Cholesterol burden in the liver induces mitochondrial dynamic changes and resistance to apoptosis
-
Converting bleomycin into a prodrug that undergoes spontaneous reactivation under physiological conditions
-
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
-
REGγ potentiates TGF-β/Smad signal dependent epithelial-mesenchymal transition in thyroid cancer cells
-
Toward safer haploidnetical hematopoietic stem cell transplantation
-
The Genomic and Immune Landscapes of Lethal Metastatic Breast Cancer
-
Potential immunotherapy for Alzheimer disease and age-related dementia
-
GDF11 exhibits tumor suppressive properties in hepatocellular carcinoma cells by restricting clonal expansion and invasion
-
ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma
-
Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes
-
Ribonucleotide reductase from Fusarium oxysporum does not Respond to DNA replication stress
-
The HERV-K accessory protein Np9 controls viability and migration of teratocarcinoma cells
-
Chromosome segregation errors generate a diverse spectrum of simple and complex genomic rearrangements
-
Fast dose fractionation using ultra-short laser accelerated proton pulses can increase cancer cell mortality, which relies on functional PARP1 protein
-
Biological implications of clonal hematopoiesis
-
Potentiating vascular-targeted photodynamic therapy through CSF-1R modulation of myeloid cells in a preclinical model of prostate cancer
-
Early Loss of Histone H2B Monoubiquitylation Alters Chromatin Accessibility and Activates Key Immune Pathways That Facilitate Progression of Ovarian Cancer
-
Mutant p53-a potential player in shaping the tumor-stroma crosstalk
-
Self-assembled micellar clusters based on Triton-X-family surfactants for enhanced solubilization, encapsulation, proteins permeability control, and anticancer drug delivery
-
RUNX represses Pmp22 to drive neurofibromagenesis
-
p53 balances between tissue hierarchy and anarchy
-
Facing the future: challenges and opportunities in adoptive T cell therapy in cancer
-
Oxidative stress and therapeutic development in lung cancer
-
The integrated stress response promotes B7H6 expression
-
Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence
-
Characterization of inv(3) cell line OCI-AML-20 with stroma-dependent CD34 expression
-
Can immunization with Bacillus Calmette-Guerin (BCG) protect against Alzheimer's disease?
-
Brain and ocular carcinomatosis diagnosed ante-mortem by cerebrospinal fluid and aqueous humor cytology in a dog
-
Global DNA methylation reflects spatial heterogeneity and molecular evolution of lung adenocarcinomas
-
Hydrophobic Organic Components of Ambient Fine Particulate Matter (PM 2.5) Associated with Inflammatory Cellular Response.
-
Acid-Induced Downregulation of ASS1 Contributes to the Maintenance of Intracellular pH in Cancer
-
Prediction of ultra-high-order antibiotic combinations based on pairwise interactions
-
Data on peptidyl platform-based anticancer drug synthesis and triton-x-based micellar clusters (MCs) self-assembly peculiarities for enhanced solubilization, encapsulation of hydrophobic compounds and their interaction with HeLa cells
-
Phenotypic Screen Identifies JAK2 as a Major Regulator of FAT10 Expression
-
Mutant p53-dependent mitochondrial metabolic alterations in a mesenchymal stem cell-based model of progressive malignancy
-
p53 and the Viral Connection: Back into the Future
-
Single cell dissection of plasma cell heterogeneity in symptomatic and asymptomatic myeloma
-
Microglial immune checkpoint mechanisms
-
P53 shades of Hippo
-
The nuclear translocation of the kinases p38 and JNK promotes inflammation-induced cancer
-
Quantitative evaluation of breast cancer response to neoadjuvant chemotherapy by diffusion tensor imaging: Initial results
-
Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers
-
Does cancer strive to minimize the cost of gene expression?
-
Regulation of dual specificity phosphatases in breast cancer during initial treatment with Herceptin: a Boolean model analysis
-
Identification of Trophectoderm-Derived Cripto as an Essential Mediator of Embryo Implantation
-
Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma
-
mRNA-seq whole transcriptome profiling of fresh frozen versus archived fixed tissues
-
Quantification and tracking of genetically engineered dendritic cells for studying immunotherapy
-
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
-
Learning by coincidence: Siamese networks and common variable learning
-
Insulin-induced translocation of IR to the nucleus in insulin responsive cells requires a nuclear translocation sequence
-
The Tumor Necrosis Factor Family: Family Conventions and Private Idiosyncrasies
-
Improvement and extension of anti-EGFR targeting in breast cancer therapy by integration with the Avidin-Nucleic-Acid-Nano-Assemblies
-
A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen
-
Mutated MITF-E87R in Melanoma Enhances Tumor Progression via S100A4
-
Systems modelling of the EGFR-PYK2-c-Met interaction network predicts and prioritizes synergistic drug combinations for triple-negative breast cancer
-
A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment
-
Transport of oxaliplatin species in water-saturated natural soil
-
Decoding the Information Contained in Fluorophore Radiation Patterns
-
Direct Real-Time Monitoring of Prodrug Activation by Chemiluminescence
-
Intratumoral bacteria may elicit chemoresistance by metabolizing anticancer agents
-
Gq-Induced Apoptosis is Mediated by AKT Inhibition That Leads to PKC-Induced JNK Activation
-
Induction of Nitric-Oxide Metabolism in Enterocytes Alleviates Colitis and Inflammation-Associated Colon Cancer
-
Expansion and Antitumor Cytotoxicity of T-Cells Are Augmented by Substrate-Bound CCL21 and Intercellular Adhesion Molecule 1
-
Irreversible modifications of receptor tyrosine kinases
-
Stepping out of the shadows: Oncogenic and tumor-promoting protein tyrosine phosphatases
-
International conference on Cell Death in Cancer and Toxicology 2018 (CDCT-2018)
-
Clinical Proteomics of Breast Cancer Reveals a Novel Layer of Breast Cancer Classification
-
Role of Telomeric TRF2 in Orosphere Formation and CSC Phenotype Maintenance Through Efficient DNA Repair Pathway and its Correlation with Recurrence in OSCC
-
Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer
-
Quiescin sulfhydryl oxidase 1 (QSOX1) glycosite mutation perturbs secretion but not Golgi localization
-
Single-Cell Genomics: A Stepping Stone for Future Immunology Discoveries
-
The Proteome of Prostate Cancer Bone Metastasis Reveals Heterogeneity with Prognostic Implications
-
Uterine Foxl2 regulates the adherence of the Trophectoderm cells to the endometrial epithelium
-
Senescence and Telomere Homeostasis Might Be Involved in Placenta Percreta-Preliminary Investigation
-
NKp46 Receptor-Mediated Interferon-gamma Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis
-
Analysis of enzymatic activity of matrix metalloproteinase (MMP) by collagen zymography in Melanoma
-
A novel role for the interleukin-1 receptor axis in resistance to anti-EGFR therapy
-
SUSHI: Sparsity-Based Ultrasound Super-Resolution Hemodynamic Imaging
-
Randomized Trial of Partial Gland Ablation with Vascular Targeted Phototherapy versus Active Surveillance for Low Risk Prostate Cancer: Extended Followup and Analyses of Effectiveness
-
Fresh water, marine and terrestrial cyanobacteria display distinct allergen characteristics
-
The tolerogenic peptide hCDR1 immunomodulates cytokine and regulatory molecule gene expression in blood mononuclear cells of primary Sjogren's syndrome patients
-
Ex-vivo organ culture as potential prioritization tool for breast cancer targeted therapy
-
Role of β-catenin in cisplatin resistance, relapse and prognosis of head and neck squamous cell carcinoma
-
Harnessing synthetic lethality to predict the response to cancer treatment
-
Cell-cell adhesion: linking Wnt/β-catenin signaling with partial EMT and stemness traits in tumorigenesis
-
Oncogenic addiction to high 26S proteasome level
-
New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins
-
Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis
-
Systemic antitumor immunity by PD-1/PD-L1 inhibition is potentiated by vascular-targeted photodynamic therapy of primary tumors
-
Phagocyte-extracellular matrix crosstalk empowers tumor development and dissemination
-
Prediction of acute myeloid leukaemia risk in healthy individuals
-
Medical Cannabis Use by Hodgkin Lymphoma Patients: Experience of a Single Center
-
Pigment Epithelium-Derived Factor and its Phosphomimetic Mutant Induce JNK-Dependent Apoptosis and P38-Mediated Migration Arrest
-
CAPN1 is a novel binding partner and regulator of the tumor suppressor NF1 in melanoma
-
Refinement of the endogenous epitope tagging technology allows the identification of a novel NRAS binding partner in melanoma
-
Single cell RNA-seq highlights a role for a partial EMT in head and neck cancer
-
Proceedings From the Fourth Haploidentical Stem Cell Transplantation Symposium (HAPLO2016), San Diego, California, December 1, 2016
-
Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures
-
Impact of X-irradiation on microglia
-
Dual role of E-cadherin in the regulation of invasive collective migration of mammary carcinoma cells
-
PAX8 activates a p53-p21-dependent pro-proliferative effect in high grade serous ovarian carcinoma
-
An exploratory study of adolescent response to fluoxetine using psychological and biological predictors
-
Toxicity of an Fc-engineered anti-CD40 antibody is abrogated by intratumoral injection and results in durable antitumor immunity
-
A sorafenib-sparing effect in the treatment of thyroid carcinoma cells attained by co-treatment with a novel isoflavone derivative and 1,25 dihydroxyvitamin D3
-
Molecular mechanisms underlying the role of galectin-8 as a regulator of cancer growth and metastasis
-
Nonredundant, highly connected microRNAs control functionality in breast cancer networks
-
Redox-Active Quinone Chelators: Properties, Mechanisms of Action, Cell Delivery, and Cell Toxicity
-
Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma
-
A Combination of Approved Antibodies Overcomes Resistance of Lung Cancer to Osimertinib by Blocking Bypass Pathways
-
Rewiring urea cycle metabolism in cancer to support anabolism
-
The Kinetics of Growth of Metallo-supramolecular Polyelectrolytes in Solution
-
IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer
-
A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation
-
Patient reported weight loss predicts recurrence rate in renal cell cancer cases after nephrectomy
-
Microenvironment-induced CD44v6 promotes early disease progression in chronic lymphocytic leukemia
-
P38 MAPK pathway and its interaction with TRF2 in cisplatin induced chemotherapeutic response in head and neck cancer
-
A biological-computational human cell lineage discovery platform based on duplex molecular inversion probes
-
Constricted migration increases DNA damage and independently represses cell cycle
-
Differentiation Between Vasogenic Edema and Infiltrative Tumor in Patients With High-Grade Gliomas Using Texture Patch-Based Analysis
-
Quantitative identification of senescent cells in cancer
-
Loss of C/EBP-beta LIP drives cisplatin resistance in malignant pleural mesothelioma
-
p53 in Bronchial Club Cells Facilitates Chronic Lung Inflammation by Promoting Senescence
-
Frustration-induced phases in migrating cell clusters
-
Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance
-
Androgen deprivation therapy potentiates the efficacy of vascular targeted photodynamic therapy of prostate cancer xenografts
-
Functional characterization of the p53 "mutome"
-
A modular platform for targeted RNAi therapeutics
-
Mechanism and medical implications of mammalian autophagy
-
Efficient Therapeutic Protein Expression Using Retroviral Replicating Vector with 2A Peptide in Cancer Models
-
Noncontrast Breast MRI During Pregnancy Using Diffusion Tensor Imaging: A Feasibility Study
-
A Mutant p53-Dependent Embryonic Stem Cell Gene Signature Is Associated with Augmented Tumorigenesis of Stem Cells
-
LATS1 and LATS2 suppress breast cancer progression by maintaining cell identity and metabolic state
-
Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition
-
Positioning Europe for the EPITRANSCRIPTOMICS challenge
-
Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies
-
Caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion
-
Age-related clonal hematopoiesis
-
Small Molecules Co-targeting CKI alpha and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models
-
Increasing intratumor C/EBP- LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer
-
Generation of reactive oxygen species by photosensitizers and their modes of action on proteins
-
The anti-inflammatory IFITM genes ameliorate colitis and partially protect from tumorigenesis by changing immunity and microbiota
-
The immune system profoundly restricts intratumor genetic heterogeneity
-
Delivery of ROS Generating Anthraquinones Using Reduction-Responsive Peptide-Based Nanoparticles
-
Helminths-based bi-functional molecule, tuftsin-phosphorylcholine (TPC), ameliorates an established murine arthritis
-
MRI radiomics analysis of molecular alterations in low-grade gliomas
-
An oligoclonal antibody durably overcomes resistance of lung cancer to third-generation EGFR inhibitors
-
Soluble SLAMF6 Receptor Induces Strong CD8 + T-cell Effector Function and Improves Anti-Melanoma Activity In Vivo
-
Role of p38 MAPK in disease relapse and therapeutic resistance by maintenance of cancer stem cells in head and neck squamous cell carcinoma
-
Nanoparticulate vaccine inhibits tumor growth via improved T cell recruitment into melanoma and huHER2 breast cancer
-
The intestinal stem cell regulating gene ASCL2 is required for L1-mediated colon cancer progression
-
Assembly and activation of the Hippo signalome by FAT1 tumor suppressor
-
Optimized dendritic cell vaccination induces potent CD8 T cell responses and anti-tumor effects in transgenic mouse melanoma models
-
A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging
-
TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma
-
Autophagy differentially regulates TNF receptor Fn14 by distinct mammalian Atg8 proteins
-
Arginine and the metabolic regulation of nitric oxide synthesis in cancer
-
Intratumor heterogeneity in epigenetic patterns
-
The oncogenic fusion protein CBFB-SMMHC downregulates CD48 to evade NK cell recognition
-
A phase I-II clinical trial of the anti-CD74 monoclonal antibody milatuzumab in frail patients with refractory chronic lymphocytic leukaemia: A patient based approach
-
Renal cell cancer: Clinicopathological profile and survival outcomes
-
LPS-mediated cell surface expression of CD74 promotes the proliferation of B cells in response to MIF
-
The HTLV-1 gp21 fusion peptide inhibits antigen specific T-cell activation in-vitro and in mice
-
Laplacian pyramid based data fusion for high resolution dynamic MRI
-
Brain investigations of rodent disease models by chemical exchange saturation transfer at 21.1T
-
SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors
-
Various stress stimuli rewire the profile of liver secretome in a p53-dependent manner
-
RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells
-
MiRNA-513a-5p inhibits progesterone receptor expression and constitutes a risk factor for breast cancer: The hOrmone and Diet in the ETiology of breast cancer prospective study
-
Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability
-
CD84 regulates PD-1/PD-L1 expression and function in chronic lymphocytic leukemia
-
Fas-L promotes the stem cell potency of adipose-derived mesenchymal cells
-
PYK2 negatively regulates the Hippo pathway in TNBC by stabilizing TAZ protein
-
Altered p53 functionality in cancer-associated fibroblasts contributes to their cancer-supporting features
-
Impaired immune surveillance accelerates accumulation of senescent cells and aging
-
WST11 Vascular Targeted Photodynamic Therapy Effect Monitoring by Multispectral Optoacoustic Tomography (MSOT) in Mice
-
Cancer research in the era of immunogenomics
-
The PTPROt tyrosine phosphatase functions as an obligate haploinsufficient tumor suppressor in vivo in B-cell chronic lymphocytic leukemia
-
Degradation of Bcl-2 by XIAP and ARTS Promotes Apoptosis
-
Dynamic proteomics reveals bimodal protein dynamics of cancer cells in response to HSP90 inhibitor
-
Augmented expression of RUNX1 deregulates the global gene expression of U87 glioblastoma multiforme cells and inhibits tumor growth in mice
-
Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine
-
Let-7b and let-7c microRNAs promote histone H2B ubiquitylation and inhibit cell migration by targeting multiple components of the H2B deubiquitylation machinery
-
Activation of the AktCREB signalling axis by a proline-rich heptapeptide confers resistance to stress-induced cell death and inflammation
-
Prediction of drug cocktail effects when the number of measurements is limited
-
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone
-
Runx3 in Immunity, Inflammation and Cancer
-
Dermatopontin augments angiogenesis and modulates the expression of transforming growth factor beta 1 and integrin alpha 3 beta 1 in endothelial cells
-
Diverse p53/DNA binding modes expand the repertoire of p53 response elements
-
Liver receptor homolog-1 (NR5a2) regulates CD95/Fas ligand transcription and associated T-cell effector functions
-
Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation
-
A point mutation in the extracellular domain of L1 blocks its capacity to confer metastasis in colon cancer cells via CD10
-
Increased NK cell immunity in a transgenic mouse model of NKp46 overexpression
-
Real Time Laser Speckle Imaging Monitoring Vascular Targeted Photodynamic Therapy
-
A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
-
p53 is essential for DNA methylation homeostasis in naive embryonic stem cells, and its loss promotes clonal heterogeneity
-
Light-Stimulated Generation of Free Radicals by Quinones-Chelators
-
Cholesterol overload in the liver aggravates oxidative stressmediated DNA damage and accelerates hepatocarcinogenesis
-
CD84 mediates CLL-microenvironment interactions
-
The not-so-long history of zebrafish research in Israel
-
Contrast enhanced ultrasound imaging can predict vascular-targeted photodynamic therapy induced tumor necrosis in small animals
-
CRISPR-assisted receptor deletion reveals distinct roles for ERBB2 and ERBB3 in skin keratinocytes
-
Non-canonical NF kappa B mutations reinforce pro-survival TNF response in multiple myeloma through an autoregulatory RelB: p50 NF kappa B pathway
-
The role of Vimentin in Regulating Cell Invasive Migration in Dense Cultures of Breast Carcinoma Cells
-
Matrix Mechanosensing: From Scaling Concepts in 'Omics Data to Mechanisms in the Nucleus, Regeneration, and Cancer
-
The short and the long: non-coding RNAs and growth factors in cancer progression
-
Biological and clinical consequences of NPM1 mutations in AML
-
Recent Advances of Individual BODIPY and BODIPY-Based Functional Materials in Medical Diagnostics and Treatment
-
P53 on the crossroad between regeneration and cancer
-
The nonreceptor tyrosine kinase c-Src attenuates SCF(β-TrCP) E3-ligase activity abrogating Taz proteasomal degradation
-
Familial chronic lymphocytic leukemia in Israel: A disproportionate distribution among Ashkenazi Jews
-
Metabolic Circuit Involving Free Fatty Acids, microRNA 122, and Triglyceride Synthesis in Liver and Muscle Tissues
-
Can immunotherapy treat neurodegeneration?
-
From Prokaryotes to Cancer: Glutamine Flux in Multicellular Units
-
Fast Vascular Ultrasound Imaging With Enhanced Spatial Resolution and Background Rejection
-
Tumor Suppression by p53: Bring in the Hippo!
-
Next-Generation Proteomics and Its Application to Clinical Breast Cancer Research
-
Activation of Signaling Cascades by Weak Extremely Low Frequency Electromagnetic Fields
-
p21 maintains senescent cell viability under persistent DNA damage response by restraining JNK and caspase signaling
-
Immune tolerance induction by nonmyeloablative haploidentical HSCT combining T-cell depletion and posttransplant cyclophosphamide
-
Monitoring In-Vivo the Mammary Gland Microstructure during Morphogenesis from Lactation to Post-Weaning Using Diffusion Tensor MRI
-
Targeting of apoptotic pathways by SMAC or BH3 mimetics distinctly sensitizes paclitaxel-resistant triple negative breast cancer cells
-
Newly formed endothelial cells regulate myeloid cell activity following spinal cord injury via expression of CD200 ligand
-
Immune deficiency augments the prevalence of p53 loss of heterozygosity in spontaneous tumors but not bi-directional loss of heterozygosity in bone marrow progenitors
-
Quantitative identification of senescent cells in aging and disease
-
Paecilomyces as a Cause of Lymph Nodes Enlargement in Hodgkins Lymphoma
-
The human lncRNA LINC-PINT inhibits tumor cell invasion through a highly conserved sequence element
-
Von Hippel-Lindau and hereditary pheochromocytoma/paraganglioma syndromes: Clinical features, genetics, and surveillance recommendations in childhood
-
Integrating multiple fitting regression and Bayes decision for cancer diagnosis with transcriptomic data from tumor-educated blood platelets
-
Herpesviruses shape tumour microenvironment through exosomal transfer of viral microRNAs
-
The LATS1 and LATS2 tumor suppressors: beyond the Hippo pathway
-
Next generation matrix metalloproteinase inhibitors Novel strategies bring new prospects
-
The microbiome in anti-cancer therapy
-
Pancreatic cancer heterogeneity and response to Mek inhibition
-
FXYD5 (dysadherin) may mediate metastatic progression through regulation of the beta-Na+-K+-ATPase subunit in the 4T1 mouse breast cancer model
-
Continuous treatment with FTS confers resistance to apoptosis and affects autophagy
-
Lymphocyte activation gene 3: A novel therapeutic target in chronic lymphocytic leukemia
-
Targeting of PYK2 synergizes with EGFR antagonists in basal-like TNBC and circumvents HER3-associated resistance via the NEDD4-NDRG1 axis
-
Classification of high-grade glioma into tumor and nontumor components using support vector machine
-
Regulatory module involving FGF13, miR-504, and p53 regulates ribosomal biogenesis and supports cancer cell survival
-
McPAS-TCR: A manually curated catalogue of pathology-associated T cell receptor sequences
-
SMYD2 lysine methyltransferase regulates leukemia cell growth and regeneration after genotoxic stress
-
Cancer and central nervous system tumor surveillance in pediatric neurofibromatosis 1
-
Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses
-
Optimization of two-compartment-exchange-model analysis for dynamic contrast-enhanced mri incorporating bolus arrival time
-
Pyruvate dehydrogenase has a major role in mast cell function, and its activity is regulated by mitochondrial microphthalmia transcription factor
-
BCAT1 restricts alpha KG levels in AML stem cells leading to IDHmut-like DNA hypermethylation
-
p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis
-
Diffusion-Weighted Breast MRI: Clinical Applications and Emerging Techniques
-
Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells
-
A recombinant fungal compound induces anti-proliferative and pro-apoptotic effects on colon cancer cells
-
C/EBP beta LIP augments cell death by inducing osteoglycin
-
Death by over-eating: The Gaucher disease associated gene GBA1, identified in a screen for mediators of autophagic cell death, is necessary for developmental cell death in Drosophila midgut
-
Development of High Affinity and High Specificity Inhibitors of Matrix Metalloproteinase 14 through Computational Design and Directed Evolution
-
Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases
-
Reduced changes in protein compared to mRNA levels across non-proliferating tissues
-
Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq
-
Direct binding of MEK1 and MEK2 to AKT induces Foxo1 phosphorylation, cellular migration and metastasis
-
miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis
-
Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome
-
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer
-
PERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy
-
Synthesis and biological evaluation of novel isoxazolines linked via piperazine to 2- benzoisothiazoles as potent apoptotic agents
-
Synonymous Somatic Variants in Human Cancer Are Not Infamous: A Plea for Full Disclosure in Databases and Publications
-
Jaspine B induces nonapoptotic cell death in gastric cancer cells independently of its inhibition of ceramide synthase
-
Tracing the origins of relapse in acute myeloid leukaemia to stem cells
-
Bombesin antagonist-based radiotherapy of prostate cancer combined with WST-11 vascular targeted photodynamic therapy
-
Suppression of VEGF-induced angiogenesis and tumor growth by Eugenia jambolana, Musa paradisiaca, and Coccinia indica extracts
-
Spontaneous Activation of Antigen-presenting Cells by Genes Encoding Truncated Homo-Oligomerizing Derivatives of CD40
-
Post-translational regulation of p53 function through 20S proteasome-mediated cleavage
-
Pancreatic cancer ascites xenograft-an expeditious model mirroring advanced therapeutic resistant disease
-
Cancer and central nervous system tumor surveillance in pediatric neurofibromatosis 2 and related disorders
-
The cancer paradigms of mammalian regeneration: Can mammals regenerate as amphibians?
-
TM7SF3, a novel p53-regulated homeostatic factor, attenuates cellular stress and the subsequent induction of the unfolded protein response
-
Involvement of Rho GAP GRAF1 in maintenance of epithelial phenotype
-
The Molecular Basis of Toxins' Interactions with Intracellular Signaling via Discrete Portals
-
AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia
-
T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences
-
The Leo Sachs legacy: A pioneers journey through hematopoiesis
-
Genetic and Functional Analysis of GRIN2A in Tumor Samples
-
Systematic Epigenomic Analysis Reveals Chromatin States Associated with Melanoma Progression
-
Mast cell tumour in the third eyelid of a mare
-
Diverse continuum of CD4+ T-cell states is determined by hierarchical additive integration of cytokine signals
-
Role of CDKN2A/p16 expression in the prognostication of oral squamous cell carcinoma
-
Rational design of nanoparticles towards targeting antigen-presenting cells and improved T cell priming
-
EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells
-
Microbiome at the Frontier of Personalized Medicine
-
Culturing CTLs under Hypoxic Conditions Enhances Their Cytolysis and Improves Their Anti-tumor Function
-
Intercellular mRNA trafficking via membrane nanotube-like extensions in mammalian cells
-
Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death
-
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors
-
A pyrrole-based natural small molecule mitigates HSP90 expression in MDA-MB-231 cells and inhibits tumor angiogenesis in mice by inactivating HSF-1
-
Recommendations for surveillance for children with leukemia-predisposing conditions
-
RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer
-
Receptor Protein Tyrosine Phosphatase alpha-Mediated Enhancement of Rheumatoid Synovial Fibroblast Signaling and Promotion of Arthritis in Mice
-
Combinatorial treatment with anacardic acid followed by TRAIL augments induction of apoptosis in TRAIL resistant cancer cells by the regulation of p53, MAPK and NFκβ pathways
-
TMPRSS2-ERG fusion protein regulates insulin-like growth factor-1 receptor (IGF1R) gene expression in prostate cancer: Involvement of transcription factor Sp1
-
The Paradox of p53: What, how, and why?
-
Co-targeting of Adenosine Signaling Pathways for Immunotherapy: Potentiation by Fc Receptor Engagement
-
Measurement of lymphocyte aggregation by flow cytometry-physiological implications in chronic lymphocytic leukemia
-
Wnt signaling in cancer stem cells and colon cancer metastasis
-
MicroRNA-182 targets SMAD7 to potentiate TGFβ-induced epithelial-mesenchymal transition and metastasis of cancer cells
-
Prolonged insulin treatment sensitizes apoptosis pathways in pancreatic β cells
-
p53 elevation in human cells halt SV40 infection by inhibiting T-ag expression
-
Imaging the DNA alkylator melphalan by CEST MRI: An advanced approach to theranostics
-
Spatiotemporal control of interferon-induced JAK/STAT signalling and gene transcription by the retromer complex
-
The Relationship Between Plasma Cytokine Levels and Response to Selective Serotonin Reuptake Inhibitor Treatment in Children and Adolescents with Depression and/or Anxiety Disorders
-
Production of Osteoclasts for Studying Protein Tyrosine Phosphatase Signaling
-
Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells
-
NKG2D ligands mediate immunosurveillance of senescent cells
-
The epigenetic landscape of T cell exhaustion
-
Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies
-
Removing silicone artifacts in diffusion-weighted breast MRI by means of shift-resolved spatiotemporally encoding
-
Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis
-
LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer
-
The relationship between the nucleolus and cancer: Current evidence and emerging paradigms
-
Ellipsoid segmentation model for analyzing light-attenuated 3D confocal image stacks of fluorescent multi-cellular spheroids
-
Tumor macrophages are pivotal constructors of tumor collagenous matrix
-
Towards the emerging crosstalk: ERBB family and steroid hormones
-
The Hippo pathway, p53 and cholesterol
-
Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
-
Oncogenic mutant p53 gain of function nourishes the vicious cycle of tumor development and cancer stem-cell formation
-
System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis
-
Prediction of multidimensional drug dose responses based on measurements of drug pairs
-
Nonthermal ablation by using intravascular oxygen radical generation with WST11: Dynamic tissue effects and implications for focal therapy
-
FXYD5 Protein Has a Pro-inflammatory Role in Epithelial Cells
-
Analysis of subcellular RNA fractions revealed a transcription- independent effect of tumor necrosis factor alpha on splicing, mediated by Spt5
-
Adipose-induced retroperitoneal soft tissue sarcoma tumorigenesis: A potential crosstalk between sarcoma and fat cells
-
The cybernetics of TNF: Old views and newer ones
-
mRNA-based dendritic cell immunization improves survival in ret transgenic mouse melanoma model
-
Mutational and network level mechanisms underlying resistance to anti-cancer kinase inhibitors
-
Interfering with the Dimerization of the ERBB Receptors by Transmembrane Domain-Derived Peptides Inhibits Tumorigenic Growth in Vitro and in Vivo
-
Emerging Role of Dysadherin in Metastasis
-
The liver-specific microRNA-122*, the complementary strand of microRNA-122, acts as a tumor suppressor by modulating the p53/mouse double minute 2 homolog circuitry
-
Differential regulated microRNA by wild type and mutant p53 in induced pluripotent stem cells
-
Identification of a Functional Risk Variant for Pemphigus Vulgaris in the ST18 Gene
-
The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation
-
ESMO/ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016
-
P53 mutations promote proteasomal activity
-
The de-ubiquitylating enzyme DUBA is essential for spermatogenesis in Drosophila
-
Dynamics inside the cancer cell attractor reveal cell heterogeneity, limits of stability, and escape
-
Non-alcoholic fatty liver and the gut microbiota
-
Widespread parainflammation in human cancer
-
DTIE, a novel core promoter element that directs start site selection in TATA-less genes
-
ADAM17 substrate release in proximal tubule drives kidney fibrosis
-
Estrogen receptor-targeted contrast agents for molecular magnetic resonance imaging of breast cancer hormonal status
-
A metabolic link between the urea cycle and cancer cell proliferation
-
The dynamic subcellular localization of ERK: Mechanisms of translocation and role in various organelles
-
PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease
-
Tumor cell invasion can be blocked by modulators of collagen fibril alignment that control assembly of the extracellular matrix
-
Treatment Effects of WST11 Vascular Targeted Photodynamic Therapy for Urothelial Cell Carcinoma in Swine
-
Tumor Necrosis Factor Alpha (TNFalpha)
-
Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma
-
Novel p53 target genes secreted by the liver are involved in non-cell-autonomous regulation
-
Parkinson disease (PARK) genes are somatically mutated in cutaneous melanoma
-
The involvement of mutant Rac1 in the formation of invadopodia in cultured melanoma cells
-
The evolution of T-cell depletion in haploidentical stem-cell transplantation
-
Microglia Replenished OHSC: A Culture System to Study In Vivo Like Adult Microglia
-
Breast MRI: Malignant Cystosarcoma Phyllodes Tumor Exhibits Unique Anisotropic Diffusion
-
Optimization of DCE-MRI protocol for the assessment of patients with brain tumors
-
Immunotherapy of cancer: From monoclonal to oligoclonal cocktails of anti-cancer antibodies: IUPHAR Review 18
-
Post-translational modification profiling - A novel tool for mapping the protein modification landscape in cancer
-
An antibody to amphiregulin, an abundant growth factor in patients' fluids, inhibits ovarian tumors
-
Adjuvant Autologous Melanoma Vaccine for Macroscopic Stage III Disease: Survival, Biomarkers, and Improved Response to CTLA-4 Blockade
-
Genetic and pharmacological modulation of Akt1 for improving ovarian graft revascularization in a mouse model
-
Extracellular matrix and tissue regeneration
-
Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation Machineries
-
Hypoxic repression of pyruvate dehydrogenase activity is necessary for metabolic reprogramming and growth of model tumours
-
Harnessing the natural inhibitory domain to control TNF alpha Converting Enzyme (TACE) activity in vivo
-
Serum thioredoxin reductase is highly increased in mice with hepatocellular carcinoma and its activity is restrained by several mechanisms
-
RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer
-
Targeting mutant p53 for cancer therapy
-
Inferring Cell-State Transition Dynamics from Lineage Trees and Endpoint Single-Cell Measurements
-
Emerging anti-cancer antibodies and combination therapies targeting HER3/ERBB3
-
Tumour suppressor death-associated protein kinase targets cytoplasmic HIF-1α for Th17 suppression
-
Intrinsic superoxide dismutase activity of MnO nanoparticles enhances the magnetic resonance imaging contrast
-
Genetic manipulation of iron biomineralization enhances MR relaxivity in a ferritin-M6A chimeric complex
-
Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement
-
Androgen deprivation therapy potentiates the efficacy of vascular targeted photodynamic therapy of prostate cancer xenografts
-
Monocyte-Derived Macrophages Contribute to Spontaneous Long-Term Functional Recovery after Stroke in Mice
-
Ramucirumab: Boon or bane
-
Fibroblast recruitment as a tool for ovarian cancer detection and targeted therapy
-
A module of inflammatory cytokines defines resistance of colorectal cancer to EGFR inhibitors
-
A novel allosteric mechanism of NF-κB dimerization and DNA binding targeted by an anti-inflammatory drug
-
Coronary vasculature patterning requires a novel endothelial ErbB2 holoreceptor
-
MicroRNAs: Non-coding fine tuners of receptor tyrosine kinase signalling in cancer
-
A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns
-
A network-based analysis of colon cancer Splicing changes reveals a tumorigenesis-favoring regulatory pathway emanating from ELK1
-
Use of HLA peptidomics and whole exome sequencing to identify human immunogenic neo-antigens
-
The Anticancer Activity of Organotelluranes: Potential Role in Integrin Inactivation
-
Breast cancer tumorigenicity is dependent on high expression levels of NAF-1 and the lability of its Fe-S clusters
-
Can diffusion tensor anisotropy indices assist in breast cancer detection?
-
Cancer therapeutic approach based on conformational stabilization of mutant p53 protein by small peptides
-
Proteomic maps of breast cancer subtypes
-
Therapeutic Potential of T Cell Chimeric Antigen Receptors (CARs) in Cancer Treatment: Counteracting Off-Tumor Toxicities for Safe CAR T Cell Therapy
-
Novel therapeutic compound tuftsin-phosphorylcholine attenuates collagen-induced arthritis
-
Genomic Alterations Observed in Colitis-Associated Cancers Are Distinct From Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease
-
Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer
-
Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery
-
The combination of trastuzumab and pertuzumab administered at approved doses may delay development of trastuzumab resistance by additively enhancing antibody-dependent cell-mediated cytotoxicity
-
The Proteome of Primary Prostate Cancer
-
Role of the microbiome in non-gastrointestinal cancers
-
Differentiation between treatment-related changes and progressive disease in patients with high grade brain tumors using support vector machine classification based on DCE MRI
-
Matrix metalloproteinase protein inhibitors: highlighting a new beginning for metalloproteinases in medicine
-
Zooming in on selectins in cancer
-
Vascular-Targeted Photodynamic Therapy in Prostate Cancer: From Bench to Clinic
-
HER2-Targeted Polyinosine/Polycytosine Therapy Inhibits Tumor Growth and Modulates the Tumor Immune Microenvironment
-
Pathology in Practice
-
The tumor as an organ: comprehensive spatial and temporal modeling of the tumor and its microenvironment.
-
Parkin Somatic Mutations Link Melanoma and Parkinson's Disease
-
Tumor evolution inferred by patterns of microRNA expression through the course of disease, therapy, and recurrence in breast cancer
-
FXYD5: Na(+)/K(+)-ATPase Regulator in Health and Disease.
-
Cellular heterogeneity mediates inherent sensitivity-specificity tradeoff in cancer targeting by Synthetic circuits
-
A non-aggressive, highly efficient, enzymatic method for dissociation of human brain-tumors and brain-tissues to viable single-cells
-
Conjugation of methotrexate-amino derivatives to macromolecules through carboxylate moieties is superior over conventional linkage to amino residues: Chemical, cell-free and in vitro characterizations
-
Bortezomib-induced pro-inflammatory macrophages as a potential factor limiting anti-tumour efficacy
-
Axonal Degeneration Is Regulated by a Transcriptional Program that Coordinates Expression of Pro- and Anti-degenerative Factors
-
Increased number of volatile organic compounds over malignant glottic lesions
-
An essential role for UTX in resolution and activation of bivalent promoters
-
SLP76 integrates into the B-cell receptor signaling cascade in chronic lymphocytic leukemia cells and is associated with an aggressive disease course
-
Tuning the proteasome to brighten the end of the journey
-
Erratum to: Phosphoproteomic analysis reveals Smarcb1 dependent EGFR signaling in Malignant Rhabdoid tumor cells
-
Multimodal Correlative Preclinical Whole Body Imaging and Segmentation
-
The Wnt target gene L1 in colon cancer invasion and metastasis
-
Protein Sialylation Regulates a Gene Expression Signature that Promotes Breast Cancer Cell Pathogenicity
-
The EGFR-HER2 module: A stem cell approach to understanding a prime target and driver of solid tumors
-
Improved Doxorubicin Encapsulation and Pharmacokinetics of Ferritin-Fusion Protein Nanocarriers Bearing Proline, Serine, and Alanine Elements
-
The ERK cascade inhibitors: Towards overcoming resistance
-
Inhibition of MMP-9 by green tea catechins and prediction of their interaction by molecular docking analysis
-
Therapy Related Acute Myeloid Leukemia with t(8;16) Mimicking Acute Promyelocytic Leukemia
-
Chronic centrosome amplification without tumorigenesis
-
A statistical framework to model the meeting-in-the-middle principle using metabolomic data: application to hepatocellular carcinoma in the EPIC study
-
Examination of HER3 targeting in cancer using monoclonal antibodies
-
Heparanase of murine effector lymphocytes and neutrophils is not required for their diapedesis into sites of inflammation
-
Preleukemia: The normal side of cancer
-
The tissue specific nature of mesenchymal stem/stromal cells: gaining better understanding for improved clinical outcomes
-
AML evolution from preleukemia to leukemia and relapse
-
The Lys-Specific Molecular Tweezer, CLR01, Modulates Aggregation of the Mutant p53 DNA Binding Domain and Inhibits Its Toxicity
-
Reactivation of epigenetically silenced miR-512 and miR-373 sensitizes lung cancer cells to cisplatin and restricts tumor growth
-
Artificial signal transduction therapy: A futuristic approach to disease treatment
-
FcγRs Modulate the Anti-tumor Activity of Antibodies Targeting the PD-1/PD-L1 Axis
-
In the hunt for therapeutic targets: Mimicking the growth, metastasis, and stromal associations of early-stage lung cancer using a novel orthotopic animal model
-
The spinal muscular atrophy with pontocerebellar hypoplasia gene VRK1 regulates neuronal migration through an Amyloid-β precursor protein-dependent mechanism
-
An interactive tool for animating biology, and its use in spatial and temporal modeling of a cancerous tumor and its microenvironment
-
Phosphorylcholine-tuftsin compound prevents development of dextransulfate-sodium-salt induced murine colitis: Implications for the treatment of human inflammatory bowel disease
-
Perspective: Consider removing inherited from definitions of pesticide resistance
-
Erratum: A Senescence-Inflammatory Switch from Cancer-Inhibitory to Cancer-Promoting Mechanism (vol 24, pg 242, 2013)
-
The role of donor-derived veto cells in nonmyeloablative haploidentical HSCT
-
Development of APE1 enzymatic DNA repair assays: Low APE1 activity is associated with increase lung cancer risk
-
More thoughts on the whole organism challenge
-
Quantitative computerized western blotting in detail
-
LPS-mediated septic shock is augmented in ceramide synthase 2 null mice due to elevated activity of TNFα-converting enzyme
-
Phosphoproteomic analysis reveals Smarcb1 dependent EGFR signaling in Malignant Rhabdoid tumor cells
-
The functional relevance of somatic synonymous mutations in melanoma and other cancers
-
Next generation HLA-haploidentical HSCT
-
The EGFR/ERBB receptor family
-
Endothelial thermotolerance impairs nanoparticle transport in tumors
-
Actin flows mediate a universal coupling between cell speed and cell persistence
-
Hyperpolarized NMR of plant and cancer cell extracts at natural abundance
-
Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis
-
Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation
-
Combining three antibodies nullifies feedback-mediated resistance to erlotinib in lung cancer
-
Genomic Classification of Cutaneous Melanoma
-
Clonal evolution models of tumor heterogeneity
-
Clusterin, a gene enriched in intestinal stem cells, is required for L1-mediated colon cancer metastasis
-
Size controlled protein nanoemulsions for active targeting of folate receptor positive cells
-
Age-associated inflammation connects RAS-induced senescence to stem cell dysfunction and epidermal malignancy
-
Peptide Anchor for Folate-Targeted Liposomal Delivery
-
Messenger RNA encoding constitutively active toll-like receptor 4 enhances effector functions of human T cells.
-
PYK2 sustains endosomal-derived receptor signalling and enhances epithelial-to-mesenchymal transition
-
Label-free in vivo molecular imaging of underglycosylated mucin-1 expression in tumour cells
-
The Parkinson's-associated protein DJ-1 regulates the 20S proteasome
-
A Novel Intravital Imaging Window for Longitudinal Microscopy of the Mouse Ovary
-
Mechanical interplay between invadopodia and the nucleus in cultured cancer cells
-
Target discovery for T cell therapy: Next steps to advance Immunotherapies
-
Chemical cross-linking and native mass spectrometry: A fruitful combination for structural biology
-
TOOKAD® Soluble focal therapy: pooled analysis of three phase II studies assessing the minimally invasive ablation of localized prostate cancer
-
Antibody-carbohydrate recognition from docked ensembles using the automap procedure
-
Electron spin resonance microscopic imaging of oxygen concentration in cancer spheroids
-
Aging, clonal hematopoiesis and preleukemia: not just bad luck?
-
Development of pheochromocytoma in ceramide synthase 2 null mice
-
Runx3 at the interface of immunity, inflammation and cancer
-
P53-dependent non-coding RNA networks in chronic lymphocytic leukemia
-
Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments
-
Regulation and function of Myb-binding protein 1A (MYBBP1A) in cellular senescence and pathogenesis of head and neck cancer
-
Dispersal of an ancient retroposon in the TP53 promoter of Bovidae: Phylogeny, novel mechanisms, and potential implications for cow milk persistency
-
Compressed sensing for longitudinal MRI: An adaptive-weighted approach
-
Regulation of Elg1 activity by phosphorylation
-
c-Abl forces YAP to switch sides.
-
Systemic Gene Silencing in Primary T Lymphocytes Using Targeted Lipid Nanoparticles
-
From mass cytometry to cancer prognosis
-
Down-regulation of LATS kinases alters p53 to promote cell migration
-
Epigenetic silencing of miR-145-5p contributes to brain metastasis
-
Historic recollections: From polymers and proteins to autoimmunity and cancer.
-
Tumor-derived osteopontin reprograms normal mammary fibroblasts to promote inflammation and tumor growth in breast cancer
-
PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells
-
Folic acid-tagged protein nanoemulsions loaded with CORM-2 enhance the survival of mice bearing subcutaneous A20 lymphoma tumors
-
Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli
-
Metabolic dysregulation in monogenic disorders and cancer-finding method in madness
-
C-Abl antagonizes the YAP oncogenic function
-
Induction of the intestinal stem cell signature gene SMOC-2 is required for L1-mediated colon cancer progression
-
Overshoot during phenotypic switching of cancer cell populations
-
Modeling the finger instability in an expanding cell monolayer
-
PYK2 integrates growth factor and cytokine receptors signaling and potentiates breast cancer invasion via a positive feedback loop
-
Aptamer Targeting the ERBB2 Receptor Tyrosine Kinase for Applications in Tumor Therapy
-
The nuclear translocation of ERK1/2 as an anticancer target
-
Determination of optimal drug dose and light dose index to achieve minimally invasive focal ablation of localised prostate cancer using WST11-vascular-targeted photodynamic (VTP) therapy
-
Inferring biological tasks using Pareto analysis of high-dimensional data
-
Photodynamic quenched cathepsin activity based probes for cancer detection and macrophage targeted therapy
-
Single Exposure to near Roadway Particulate Matter Leads to Confined Inflammatory and Defense Responses: Possible Role of Metals
-
Cancer immunotherapy: More is (much) better
-
The role of C/EBP-β LIP in multidrug resistance
-
Combined local blood-brain barrier opening and systemic methotrexate for the treatment of brain tumors
-
Cardiac glycosides induced toxicity in human cells expressing α1-, α2-, or α3-isoforms of Na-K-ATPase
-
Erratum to FcγRs Modulate the Anti-tumor Activity of Antibodies Targeting the PD-1/PD-L1 Axis [Cancer Cell 28, 285-295; September 14, 2015]
-
The polyomavirus middle T-antigen oncogene activates the Hippo pathway tumor suppressor Lats in a Src-dependent manner
-
Exercising 'veto' power to make haploidentical hematopoietic stem cell transplantation a safe modality for induction of immune tolerance
-
MicroRNAs and growth factors: An alliance propelling tumor progression
-
Laparoscopic versus open liver resection for metastatic colorectal cancer
-
Overcoming limitations in diffusion-weighted MRI of breast by spatio-temporal encoding
-
YAP and the drug resistance highway
-
MRNA-transfected Dendritic Cells Expressing Polypeptides That Link MHC-I Presentation to Constitutive TLR4 Activation Confer Tumor Immunity
-
Haploidentical hematopoietic stem cell transplantation: State of art
-
Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody
-
Tumor Suppressor Activity of Klotho in Breast Cancer is Revealed by Structure-function Analysis.
-
Matrix Metalloproteinase Biology
-
Tumor-specific expression and detection of a CEST reporter gene
-
Serum Creatinine Versus Plasma Methotrexate Levels to Predict Toxicities in Children Receiving High-dose Methotrexate
-
Regulation of epithelial cell organization by tuning cell-substrate adhesion
-
EGF induces microRNAs that target suppressors of cell migration: MiR-15b targets MTSS1 in breast cancer
-
Tumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant
-
Receptor tyrosine kinases: Structure, functions and role in human disease
-
Inflammatory mechanisms of infection-associated cancer
-
Modeling and Predicting Optimal Treatment Scheduling Between the Antiangiogenic Drug Sunitinib and Irinotecan in Preclinical Settings
-
Tyrosine phosphorylation of WW proteins
-
Chromosome 7 gain and DNA hypermethylation at the HOXA10 locus are associated with expression of a stem cell related HOX-signature in glioblastoma
-
Tumor-associated and disease-associated autoantibody repertoires in healthy colostrum and maternal and newborn cord sera
-
Biopsy-induced inflammatory conditions improve endometrial receptivity: The mechanism of action
-
Recurrent inactivating RASA2 mutations in melanoma
-
The tyrosine kinase c-Abl promotes homeodomaininteracting protein kinase 2 (HIPK2) accumulation and activation in response to DNA damage
-
Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer
-
Gap geometry dictates epithelial closure efficiency
-
Collective cell motility promotes chemotactic prowess and resistance to chemorepulsion
-
Physics of active jamming during collective cellular motion in a monolayer
-
The cancer genome
-
The MAPK Signaling Cascades
-
The BH3-only protein BID impairs the p38-mediated stress response and promotes hepatocarcinogenesis during chronic liver injury in mice
-
Clinico-Pathological Correlation of β-Catenin and Telomere Dysfunction in Head and Neck Squamous Cell Carcinoma Patients
-
Hepatitis B virus induces RNR-R2 expression via DNA damage response activation
-
Extracellular matrix regulation of ErbB3 in a subset of wild-type BRAF/NRAS melanoma
-
Fluorine-19 labeling of stromal vascular fraction cells for clinical imaging applications
-
Pathway-based personalized analysis of breast cancer expression data
-
Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression
-
P53 orchestrates between normal differentiation and cancer
-
The molecular basis for functional plasticity in type I interferon signaling
-
ErbB3-ErbB2 complexes as a therapeutic target in a subset of wild-type BRAF/NRAS cutaneous melanomas